• 대한기계학회논문집A
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• 제20권7호
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• pp.2108-2117
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• 1996

The purpose of this paper is to investigate the influence of the exciter attached for the measurement of natural frequencies when extracting the frequency response functions of the test structure in experimental modal analysis. The procedure is first to model the attached exciter as an additional degree of freedom system and next to verify the suggested model by experimentally extracting the natural frequencies of the test structure with various values of exciter mass, stinger stiffness and attachment position of the exciter on the test structure. It is concluded that as additional degree of freedom system which includes the natural frequency of the exciter itself and axial stiffness of stinger should be considered to quantatively define the coupling effects of structure-exciter interaction on the measured natural frequencies. It is not the mass of the exciter itself but the coupling effect of the additional degree of freedom mass-spring system consisting of exciter body and armature coil that characterizes the natural frequency deviation. Therefore, when the natural frequency of this additional mass-spring system is outside of the test frequency range, the coupling effect of structure-exciter interaction can be minimized.

• Structural Engineering and Mechanics
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• 제26권2호
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• pp.111-126
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• 2007

Dynamic responses of the bridge for a straddle-type monorail subjected to the ground motion of high probability to occur are investigated by means of a three-dimensional traffic-induced vibration analysis to clarify the effect of a train's dynamic system on seismic responses of a monorail bridge. A 15DOFs model is assumed for a car in the monorail train. The validity of developed equations of motion for a monorail train-bridge interaction system is verified by comparison with the field-test data. The inertia effect due to a ground motion is combined with the monorail train-bridge interaction system to investigate the seismic response of the monorail bridge under a moving train. An interesting result is that the dynamic system of the train on monorail bridges can act as a damper during earthquakes. The observation of numerical results also points out that the damper effect due to the dynamic system of the monorail train tends to decrease with increasing speed of the train.

• 전산구조공학
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• 제10권2호
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• pp.243-254
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• 1997

기초 지반상에 존재하는 3차원 골조구조물에 진동을 유발시키는 기계하중, 풍하중, 지진과 같은 동적 하중이 작용한다면, 지반-골조구조물 상호작용계의 동적거동을 해석하여야한다. 따라서, 본 연구에서는 실제 구조물에 근접한 기하학적 형상으로 이상화 시키기 위해, 슬래브와 기초판은 유연성을 갖는 4-절점 판요소, 보.기둥은 2-절점 보요소, 탄성지반은 8-절점 입체요소를 사용하여 유한요소법으로 3차원 상호작용계를 해석하였다. 본 연구의 목적은 지반-골조구조물 상호작용계의 동적 거동을 해석하기 위해, 동적 운동 방정식을 정리한 후 유한요소 프로그램으로 상호작용계의 동적 거동을 해석하는 것이다.

• Journal of Information Processing Systems
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• 제8권3호
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• pp.459-470
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• 2012

Recently, high-throughput technologies such as the two-hybrid system, protein chip, Mass Spectrometry, and the phage display have furnished a lot of data on protein-protein interactions (PPIs), but the data has not been accurate so far and the quantity has also been limited. In this respect, computational techniques for the prediction and validation of PPIs have been developed. However, existing computational methods do not take into account the fact that a PPI is actually originated from the interactions of domains that each protein contains. So, in this work, the information on domain modules of individual proteins has been employed in order to find out the protein interaction relationship. The system developed here, WASPI (Web-based Assistant System for Protein-protein interaction Inference), has been implemented to provide many functional insights into the protein interactions and their domains. To achieve those objectives, several preprocessing steps have been taken. First, the domain module information of interacting proteins was extracted by taking advantage of the InterPro database, which includes protein families, domains, and functional sites. The InterProScan program was used in this preprocess. Second, the homology comparison with the GO (Gene Ontology) and COG (Clusters of Orthologous Groups) with an E-value of $10^{-5}$, $10^{-3}$ respectively, was employed to obtain the information on the function and annotation of each interacting protein of a secondary PPI database in the WASPI. The BLAST program was utilized for the homology comparison.

• Human Ecology Research
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• 제57권1호
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• pp.109-125
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• 2019

Few studies have utilized observational methods in the field of couple research even though using self-report questionnaires is prone to the subjective biases of the reporter. This study validates the Marital Interaction Coding System-Global (MICS-G), a global version of the well-established microanalytic observational coding system, Marital Interaction Coding System (MICS). Participants in the study consisted of 30 married couples with varied levels of marital adjustment who visited one of the Healthy Family and Multicultural Family Support Centers in Seoul, either for couple therapy or the "Marriage Checkup"program. Ten-minute problem-solving discussions were rated by two undergraduate student raters who were trained for 10 hours. Interobserver agreement based on percentage agreement and intraclass correlation coefficients showed a high level of agreement between raters in establishing interrater reliability. Convergent validity was established by: correlations among marital adjustment, psychological aggression, mental health, and MICS-G categories of conflicts, validation, invalidation, facilitation, and withdrawal. MICS-G categories also were successful in discriminating between distressed and nondistressed couples, which provides evidence of discriminant validity for MICS-G. This study showed that MICS-G is a promising method for researchers to observe couple interactions in a more cost-effective way. Methodological issues and practical applications are also discussed.

• Journal of Microbiology and Biotechnology
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• 제12권2호
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• pp.286-291
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• 2002

Histone deacetylase I (HDAC1) works as one of the components in a nucleosome remodeling (NuRD) complex that consists of several proteins, including metastasis-associated protein 1 (MTA1). Since the protein-protein interaction of HDAC1 and MTA1 would appear to be important for both the integrity and functionality of the HDAC1 complex, the interruption of the HDAC1 and MTA1 interaction may be an efficient way to regulate the biological function of the HDAC1 complex. Based on this idea, a yeast two-hybrid system was constructed with HDAC1 and MTA1 expressing vectors in the DNA binding and activation domains, respectively. To verify the efficiency of the assay system, 3,500 microbial metabolite libraries were tested using the paper disc method, and KB0699 was found to inhibit the HDAC1 and MTA1 interaction without any toxicity to the wild-type yeast. Furthermore, KB0699 blocked the interaction of HDAC1 and MTA1 in an in vitro GST pull down assay and induced morphological changes in B16/BL6 melanoma cells, indicating the interruption of the HDAC1 complex function. Accordingly, these results demonstrated that the yeast assay strain developed in this study could be a valuable tool for the isolation of a HDAC1 complex disruptor.

• Structural Engineering and Mechanics
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• 제17권3_4호
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• pp.573-591
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• 2004

A hybrid control system is presented for seismic-resistant building structures with and without soil-structure interaction (SSI). The hybrid control is a damper-actuator-bracing control system composed of passive and active controllers. An intelligent algorithm is developed for the hybrid system, in which the passive damper is designed for minor and moderate earthquakes and the active control is designed to activate when the structural response is greater than a given threshold quantity. Thus, the external energy for active controller can be optimally utilized. In the control of a multistory building, the controller placement is determined by evaluating the optimal location index (OLI) calculated from six earthquake sources. In the study, the soil-structure interaction is considered both in frequency domain and time domain analyses. It is found that the interaction can significantly affect the control effectiveness. In the hybrid control algorithm with intelligent strategy, the working stages of passive and active controllers can be different for a building with and without considering SSI. Thus SSI is essential to be included in predicting the response history of a controlled structure.

• 드라이브 ㆍ 컨트롤
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• 제16권4호
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• pp.65-73
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• 2019

In this study, flow analysis and fluid-solid interaction analysis were conducted on a hollow fiber membrane module used for analysis of dehumidification characteristics. To ensure the reliability of the flow analysis results, the dehumidification experiment was performed under the temperature of 30℃ and relative humidity of 30% RH. The results of the dehumidification experiments were compared with the flow analysis results. The results of dehumidification experiments and flow analysis had a difference of approximately 5%. A 1-Way fluid-solid interaction analysis with various materials was conducted. From the results, it was found that the baffle with the largest shape deformation (polyethylene material) was subjected to 2-way fluid-solid interaction. The analysis of fluid flow and dehumidification characteristics were analyzed according to the shape deformation of the baffle.

• Coupled systems mechanics
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• 제3권3호
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• pp.267-289
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• 2014

A proper physical modeling of infilled building frame-foundation beam-soil mass interaction system is needed to predict more realistic and accurate structural behavior under static vertical loading. This is achieved via finite element method considering the superstructure, foundation and soil mass as a single integral compatible structural unit. The physical modelling is achieved via use of finite element method, which requires the use of variety of isoparametric elements with different degrees of freedom. The unbounded domain of the soil mass has been discretized with coupled finite-infinite elements to achieve computational economy. The nonlinearity of soil mass plays an important role in the redistribution of forces in the superstructure. The nonlinear behaviour of the soil mass is modeled using hyperbolic model. The incremental-iterative nonlinear solution algorithm has been adopted for carrying out the nonlinear elastic interaction analysis of a two-bay two-storey infilled building frame. The frame and the infill have been considered to behave in linear elastic manner, whereas the subsoil in nonlinear elastic manner. In this paper, the computational methodology adopted for nonlinear soil-structure interaction analysis of infilled frame-foundation-soil system has been presented.

• Journal of Advanced Marine Engineering and Technology
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• 제21권4호
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• pp.372-380
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• 1997

This paper describes experimental investigations of helium-air exchange flows through parti¬tioned opening and two-opening. Such exchange flows may occur following rupture accident of stand pipe in high temperature gas cooled reactor. A test vessel with the two types of small open¬ing on top of test cylinder is used for experiments. An estimation method of mass increment is developed and applied to measure the exchange flow rate. A technique of flow visualization by Mach-Zehnder interferometer is provided to recognize the exchange flows. In the case of exchange flow through the partitioned opening, flow passages of upward flow of the helium and downward flow of the air within the opening are separated by vertical partition, and the two flows interact out of entrance and exit of the opening. Therefore, an experiment of the exchange flow through two-opening is made to investigate effect of the fluids interaction of the partitioned opening sys¬tem. As a result of comparison of the exchange flow rates between the two types of the opening system, it is found that the exchange flow rate of the two-opening system is larger than that of the partitioned opening system due to absence of the effect of fluids interaction. Finally, the fluids interaction between the upward and downward flows through the partitioned opening is found to be an important factor on the helium-air exchange flow.