• Archives of Pharmacal Research
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• 제29권12호
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• pp.1171-1178
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• 2006

This study examined the effects of flavors, which are usually added to improve the appeal of pharmaceutical agents, on the viscosity and gelling point of 18% (w/w) aqueous poloxamer 407 solutions. Monoterpenes, esters, alcohols, aldehyde ketones and lactone type flavors were examined. The concentrations of flavor ranged from 0.1 to 1.0%(w/w). After adding a flavor to the aqueous poloxamer 407 solution, the viscosity of the solution was measured using a Brookfield viscometer, and the gelling point was determined from the viscosity vs. temperature plot. The gelling point of the aqueous poloxamer 407 solution decreased with increasing concentration of flavors except for coumarin, vanillin and ethylvanillin. Thermal analysis with DSC showed an interaction between the flavors and poloxamer 407. These results suggest that the flavors bind to the hydrophilic end chains of poloxamer 407, which increases the viscosity, causing gelation at lower temperatures.

• 한국축산식품학회지
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• 제36권3호
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• pp.291-299
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• 2016

Interaction between carcass quality grade and end-point cooking temperature on eating quality of Hanwoo m. longissimus was investigated. Ten (10) of steers were sampled from a commercial population; carcasses with QG 1⁺⁺ (n=5) and QG 1 (n=5) were chosen. Samples were cooked by electric oven at 60 or 82℃ and compared with uncooked control samples. The pH was not affected by cooking temperature but decreased the redness after cooking and steaks cooked at 60℃ were more reddish than steaks cooked at 82℃ in both QG groups. Higher cooking temperature greatly (p<0.05) increased the cooking loss, but there was no significant interaction between cooking temperature and QG on the cooking loss. Moisture is negatively correlated with temperature in both QG while the proportionate relationship between crude fat and end-point temperature found in QG 1⁺⁺. WBSF values were significantly (p<0.05) high for QG 1, while that was significantly (p<0.05) increased when the temperature continues to increase. The increasing quality grade of beef resulted in significant higher (p<0.01) level of TBARS and cooking temperature increased TBARS content. Fatty acid composition was not altered by cooking at both temperatures and also the amount of fat intake was not changed. The current study indicates that eating quality of beef m. longissimus was greatly influenced by end-point temperature being interacted with QG. However, the amount and composition of fat were stable regardless of end-point temperatures. These results will provide a consumer reference to determine cooking conditions and intramuscular fat content.

• 한국초등과학교육학회지:초등과학교육
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• 제37권4호
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• pp.402-415
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• 2018

This study aims to inquire into the U. S. elementary school teachers' storylines for science teaching methods, scientific knowledge and interactions with students. As research subjects, two American elementary school teachers, named Christina and Melissa, were selected. As test tools, this study adopted Storyline Test and semi-structured interviews. Firstly, in regard to the science teaching method, Christina evaluated that she gradually improved her science teaching skills up to positive 6 points, starting from 2 points in the first year of teaching career, while Melissa sustained a stable state with 5 points in the 9th year of teaching career, starting from 1 point in the first year of teaching career. It was found that both the teachers had more confidence in their science teaching methods by participating in various training programs. Secondly, Christina evaluated her scientific knowledge in the first year of teaching career as 4 points, but evaluated her present scientific knowledge as stable as 6 points since she started studying teaching materials actively, discussing with other teachers and having more ability of application through science class integrated with other school subjects, in the 7th year of her teaching career. On the other hand, Melissa evaluated her scientific knowledge in the first year of teaching career as 1 point since she did not exactly know what to teach elementary school students, but in the 6th year of teaching career, she sustained a stable state with points through joint-activities with other teachers. It was found that chances to research with other teachers had important effect on both the teachers' confidence in scientific knowledge. Thirdly, in regard to interactions with students in science class, Christina said that she did not have any interaction with students when instructing inquiry activities in the first year of teaching career, but since the 10th year of her teaching career, she had sustained a stable state with 6 points through active interaction with students, by leading learning projects and science competitive exhibitions, etc. On the other hand, Melissa evaluated her interaction with students in the first year of teaching career as 1 point because her class was reading-oriented, but since the 9th year of teaching career, she had sustained a stable state with 6 points so far, by developing inquiry activity strategies to improve interaction with students. Overall, it was found that inquiry activities played a central role in improving both the teachers' interaction with students.

• 한국유체기계학회 논문집
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• 제7권3호
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• pp.14-22
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• 2004

Bileaflet mechanical valves have the complications such as hemolysis and thromboembolism, leaflet damage, and leaflet break. These complications are related with the fluid velocity and shear stress characteristics of mechanical heart valves. The first aim of the current study is to introduce fluid-structure interaction method for calculation of unsteady and three-dimensional blood flow through bileaflet valve and leaflet behavior interacted with its flow, and to overcome the shortness of the previous studies, where the leaflet motion has been ignored or simplified, by using FSI method. A finite volume computational fluid dynamics code and a finite element structure dynamics code have been used concurrently to solve the flow and structure equations, respectively, to investigate the interaction between the blood flow and leaflet. As a result, it is observed that the leaflet is closing very slowly at the first stage of processing but it goes too fast at the last stage. And the results noted that the low pressure is formed behind leaflet to make the cavitation because of closing velocity three times faster than opening velocity. Also it is observed some fluttering phenomenon when the leaflet is completely opened. And the rebounce phenomenon due to the sudden pressure change of before and after the leaflet just before closing completely. The some of time-delay is presented between the inversion point of ventricle and aorta pressure and closing point of leaflet. The shear stress is bigger and the time of exposure is longer when the flow rate is maximum. So it is concluded that the distribution of shear stress at complete opening stage has big effect on the blood damage, and that the low-pressure region appeared behind leaflet at complete closing stage has also effect on the blood damage.

• Steel and Composite Structures
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• 제9권2호
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• pp.131-158
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• 2009

This paper presents a modelling technique for the nonlinear analysis of composite steel-concrete beams with partial shear interaction. It extends the applicability of two stiffness elements previously derived by the authors using the direct stiffness method, i.e. the 6DOF and the 8DOF elements, to account for material nonlinearities. The freedoms are the vertical displacement, the rotation and the slip at both ends for the 6DOF stiffness element, as well as the axial displacement at the level of the reference axis for the 8DOF stiffness element. The solution iterative scheme is based on the secant method, with the convergence criteria relying on the ratios of the Euclidean norms of both forces and displacements. The advantage of the approach is that the displacement and force fields of the stiffness elements are extremely rich as they correspond to those required by the analytical solution of the elastic partial interaction problem, thereby producing a robust numerical technique. Experimental results available in the literature are used to validate the finite element proposed in the paper. For this purpose, those reported by Chapman and Balakrishnan (1964), Fabbrocino et al. (1998, 1999) and Ansourian (1981) are utilised; these consist of six simply supported beams with a point load applied at mid-span inducing positive bending moment in the beams, three simply supported beams with a point load applied at mid-span inducing negative bending moment in the beams, and six two-span continuous composite beams respectively. Based on these comparisons, a preferred degree of discretisation suitable for the proposed modelling technique expressed as a function of the ratio between the element length and depth is proposed, as is the number of Gauss stations needed. This allows for accurate prediction of the nonlinear response of composite beams.

• 한국작물학회지
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• 제35권1호
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• pp.58-64
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• 1990

최근 국내에서 연구가 시작되고 있는 신규 식물생장조정제인 brassinolide류와 기존의 auxin류를 혼용하였을 경우 상호작용성을 구명하여 농업적 이용의 기초자료를 얻고자 몇가지 생물검정법을 이용하여 상호작용의 결과를 분석해 본 결과를 요약하면 다음과 간다. 1. 벼 엽신기부굴절검정에서는 두 화합물의 저농도 혼용조합에서 길항적인 반응을 보였으나, 대부분의 조합에서는 상가 또는 상승작용을 하였으며, 고농도의 혼용일수록 상승효과가 높았고, IAA가 2, 4-D에 비해 다소 혼용효과가 높았다. 2. 귀리 자엽소신장검정에서는 HBR의 농도에 관계없이 IAA 0.1ppm 이하에서는 상승작용을 하였으나 0.3ppm 이상의 혼용에서는 상가적인 반응을 나타내었다. 3. 무 하배축신장검정에서는 자엽의 유무에 의해 반응이 다르게 나타났는데, 자엽을 제거한 절편에서는 IAA 3ppm과 HBR과의 혼용조합을 제외하고는 대부분의 혼용조합이 길항적인 반응을 보였다. 4. 이상에서와 같이 검정방법간 혼용효과가 뚜렷한 차이가 있었으며, 공시재료에 따라 상호작용의 효과가 다르게 나타났는데 auxin의 함량이 비교적 높은 생장점을 가진 절편에서는 대체로 길항작용을 보인 반면, 선단부를 제거하여 내생호르몬이 불안정한 절편에서는 상가 또는 상승작용을 보였다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2007년도 춘계종합학술대회
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• pp.883-886
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• 2007

본 연구는 웹기반 교육 체제에서의 학습자가 교육목표를 달성하는 데 있어 중요한 역할을 하는 인터랙션을 컨텐츠적 측면과 연관지어 분석해 봄으로서 궁극적으로 학습자에게 보다 만족스러운 인터랙션을 제공하는 웹기반 교육 사이트의 설계 전략을 모색하는 데 목적이 있다. 우선 문헌연구를 통해 웹기반 교육과 인터랙션에의 개념 및 의의를 고찰하여 웹기반 교육 설계원리들이 실제 웹기반 교육사이트에서 어떻게 이루어지고 있는지 상호작용 측면에서 분석하여 기존 수업의 어떤 요소를 충분히 활용하고 어떤 요소를 보강하여야 할지 알아보았다. 그 결과 웹기반 교육사이트들은 사회적측면의 인터랙션보다는 시스템측면의 인터랙션으로 '정보'를 전달하기 위한 커뮤니케이션 디자인에 기반한 컬러, 텍스트, 이미지 등 시스템 '각각의 디자인 요소'들과의 인터랙션을 더 활용하고 있는 것으로 나타났다.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2002년도 유체기계 연구개발 발표회 논문집
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• pp.33-40
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• 2002

The hydraulic performance analysis of a pump system composed of an inducer and impeller for the application on turbopumps has been performed using three-dimensional Wavier-Stokes equations. A simple mixing-plane method and a full interaction method are used to simulate inducer/impeller interactions. The computations adopting two methods show almost similar results due to the weak interaction between the inducer and impeller since the inducer outlet blade angle is rather small. But, because the inducer and the impeller are closely spaced near the shroud region at the interface, flow angles at the impeller inlet show different results between two methods. Thus, the full interaction method predicted about $2\%$ higher pump performance than the mixing-plane method. And the effects of prewhirl at the impeller inlet are also investigated. As the inlet flow angle is increased, the head rise and the efficiency are decreased. The computational results are compared with experimental ones. The computational results at the design point show good agreements with experimental data. But the computation was found to under-predict the head rise at high mass flow rates compared to the experiment, further study must be followed in terms of the computation and experiment.

• 한국실내디자인학회논문집
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• 제20권1호
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• pp.173-181
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• 2011

Contemporary architecture has shown interest in surface after breaking off the relation with structure. Also, the development of contemporary media has brought the great change to the surface of architecture. Interaction among the people, architecture, and environment is also the main point of interest in adapting the role of media to the architecture. But contemporary media itself have been applied on surface in architecture lately. So, it is purpose of the study to analyze the contemporary media characteristics application on the surfaces of EXPO pavilions based on the related characteristics of interaction effects. The categories and the contents for the frame of case studies were arranged through document research and field study. Case studies were focused on the pavilions of the World Exposition Shanghai China 2010. Surface can make the interaction between human and architecture more dramatically by the application the role of media. It was analyzed through the study that the interaction level of people is the important issue shared in digital or analog media application on surface of pavilion. The complementary relationship between surface of contemporary architecture and contemporary media can be manipulated and enriched by the application of various style of media on surface.

• BMB Reports
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• 제34권2호
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• pp.102-108
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• 2001

A time-dependent folding process was used to determine whether or not protein disulfide isomerase (PDI) plays an important role in the maturation of nascent lactoferrin polypeptides. Interaction between lactoferrin and PDI was analyzed according to the co-immunoprecipitation of the two proteins. The results indicate that lactoferrin folding requires a significant interaction with PDI and its binding is relatively brief compared to other nascent polypeptides. The amount of lactoferrin interacting with PDI increases up to half a minute and sharply decreases beyond this time point. During the refolding process that follows reduction by DTT, lactoferrin polypeptides heavily interact with PDI and the interaction period was extended compared to the normal folding process. In terms of the temperature effect on PDI-lactoferrin interaction, PDI binds to lactoferrin polypeptides longer at a lower temperature (here, $25^{\circ}C$) than $37^{\circ}C$. The lactoferrin-PDI interaction was also studied in vitro. According to the in vitro experiment data, PDI was still functional in cell lysates assisting lactoferrin folding into the mature form. PDI interacts with lactoferrin polypeptides for an extended period during the folding in vitro. During the refolding process in vitro, intermolecular aggregates and refolding oligomers matured into a functional form after PDI binds to the lactoferrin. These results suggest that PDI provides a prolonged chaperoning activity in the refolding processes and that there appears to be a greater requirement for PDI chaperone activity in the refolding of lactoferrin polypeptides.