• Title/Summary/Keyword: Interaction Modeling

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The Longitudinal Relationship among Paternal Involvement, Maternal Parenting Stress, Psychosocial Development of Infant during Infancy and Peer Interactions during Childhood (영아기 아버지 양육참여, 어머니 양육스트레스, 영아 심리사회발달과 유아기 또래상호작용 간의 종단적 관계 분석)

  • Jang, Hyo Eun;Kim, Choon Kyung
    • Korean Journal of Child Education & Care
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    • v.18 no.1
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    • pp.77-102
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    • 2018
  • The objectives of this study were to analyze the longitudinal mediation effects of maternal parenting stress and psychosocial development of infant on the influence of paternal involvement during infancy to children's peer interactions. For these objectives, latent growth modeling was used and adapted to the data taken from the Panel Study on Korean Children(PSKC), Wave I (0-year olds) to Wave III (2-year olds) and Wave V(4-year olds) to Wave VII(6-year olds). During a total of six years, 1,018 parent responded. The major results of this study were as follows. First, maternal parenting stress(initial status) had a significant mediating effect on the influence of paternal involvement(initial status) to children's play interaction(initial status). Second, maternal parenting stress(initial status/change rate) had a longitudinal mediating eff ect on the influence of paternal involvements(initial status/change rate) to children's play disruption-disconnection interactions(initial status/change rate). Third, psychosocial development of infants(initial status/change rate) had a longitudinal mediating effect on the influence of paternal involvement(initial status/change rate) to children's play interactions(initial status/change rate). Fourth, psychosocial development of infant(initial status) had a significant mediating effect on the influence of paternal involvement(initial status) to children's play disruption-disconnection interactions(initial status). The implications of the findings of the current study and suggestions for future research were also discussed.

Multi-DOF Real-time Hybrid Dynamic Test of a Steel Frame Structure (강 뼈대 구조물의 다자유도 실시간 하이브리드 동적 실험)

  • Kim, Sehoon;Na, Okpin;Kim, Sungil
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.33 no.2
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    • pp.443-453
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    • 2013
  • The hybrid test is one of the most advanced test methods to predict the structural dynamic behavior with the interaction between a physical substructure and a numerical modeling in the hybrid control system. The purpose of this study is to perform the multi-directional dynamic test of a steel frame structure with the real-time hybrid system and to evaluate the validation of the results. In this study, FEAPH, nonlinear finite element analysis program for hybrid only, was developed and the hybrid control system was optimized. The inefficient computational time was improved with a fixed number iteration method and parallel computational techniques used in FEAPH. Furthermore, the previously used data communication method and the interface between a substructure and an analysis program were simplified in the control system. As the results, the total processing time in real-time hybrid test was shortened up to 10 times of actual measured seismic period. In order to verify the accuracy and validation of the hybrid system, the linear and nonlinear dynamic tests with a steel framed structure were carried out so that the trend of displacement responses was almost in accord with the numerical results. However, the maximum displacement responses had somewhat differences due to the analysis errors in material nonlinearities and the occurrence of permanent displacements. Therefore, if the proper material model and numerical algorithms are developed, the real-time hybrid system could be used to evaluate the structural dynamic behavior and would be an effective testing method as a substitute for a shaking table test.

Classification Tree Analysis to Assess Contributing Factors Influencing Biosecurity Level on Farrow-to-Finish Pig Farms in Korea (분류 트리 기법을 이용한 국내 일괄사육 양돈장의 차단방역 수준에 영향을 미치는 기여 요인 평가)

  • Kim, Kyu-Wook;Pak, Son-Il
    • Journal of Veterinary Clinics
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    • v.33 no.2
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    • pp.107-112
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    • 2016
  • The objective of this study was to determine potential contributing factors associated with biosecurity level of farrow-to-finish pig farms and to develop a classification tree model to explore how these factors related to each other based on prediction model. To this end, the author analyzed data (n = 193) extracted from a cross-sectional study of 344 farrow-to-finish farms which was conducted between March and September 2014 aimed to explore swine disease status at farm level. Standardized questionnaires with information about basic demographical data and management practices were collected in each farm by on-site visit of trained veterinarians. For the classification of the data sets regarding biosecurity level as a dependent variable and predictor variables, Chi-squared Automatic Interaction Detection (CHAID) algorithm was applied for modeling classification tree. The statistics of misclassification risk was used to evaluate the fitness of the model in terms of prediction results. Categorical multivariate input data (40 variables) was used to construct a classification tree, and the target variable was biosecurity level dichotomized into low versus high. In general, the level of biosecurity was lower in the majority of farms studied, mainly due to the limited implementation of on-farm basic biosecurity measures aimed at controlling the potential introduction and transmission of swine diseases. The CHAID model illustrated the relative importance of significant predictors in explaining the level of biosecurity; maintenance of medical records of treatment and vaccination, use of dedicated clothing to enter the farm, installing fence surrounding the farm perimeter, and periodic monitoring of the herd using written biosecurity plan in place. The misclassification risk estimate of the prediction model was 0.145 with the standard error of 0.025, indicating that 85.5% of the cases could be classified correctly by using the decision rule based on the current tree. Although CHAID approach could provide detailed information and insight about interactions among factors associated with biosecurity level, further evaluation of potential bias intervened in the course of data collection should be included in future studies. In addition, there is still need to validate findings through the external dataset with larger sample size to improve the external validity of the current model.

The Link between Number of Sales Accounts and Salespeople's Performance (영업사원의 거래처 수와 영업성과 간의 관계에 관한 연구)

  • Cho, Yeonjin
    • Journal of Distribution Science
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    • v.17 no.1
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    • pp.105-115
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    • 2019
  • Purpose - Previous research has shown that a very high level and a very low level of job scope can both be more stressful than intermediate levels of job scope. This study investigates the potential positive and negative effects of the number of accounts handled by sales personnel. The primary objective of this paper is to examine how the number of accounts salespeople handle affects their stress and performance. Research design, data, and methodology - This research conducted the data collection using a survey of salespeople in the pharmaceutical industry. I sent the survey to 420 salespeople, and received 318 usable responses. To assess measurement reliability and validity, I ran an exploratory and confirmatory factor analysis. I also employed structural equation modeling (SEM) to test all hypothesized effects in AMOS and also measured the interaction variable using Ping's (1996) approach. Results - These results show that there are linear and non-linear effects of the number of accounts handled by the salesperson on both role ambiguity and role conflict. First, the number of accounts handled by a salesperson is positively related to role ambiguity and role conflict. Second, the effect of the number of accounts handled on role ambiguity and role conflict decreases as the number of accounts handled by the salesperson increases. Third, as accounts increase from a low level, role stress increases; when the number of accounts reaches an optimal level, role stress decreases; and when the number of accounts increases to a high level, it can be detrimental to the salesperson's role stress. Fourth, while product complexity is positively related to role ambiguity, brand strength is negatively related to both role ambiguity and role conflict. Fifth, the greater the brand strength, the weaker the relationship will be between the number of accounts handled and salesperson role ambiguity. Finally, role ambiguity is positively related to salesperson performance. Conclusion - Too much and too little accounts increase the role ambiguity and role conflict of salespersons. Managers should identify the complex effect of the number of accounts handled by salespeople. Also, when products are complex, managers should provide training to eliminate any complex processes and complex information. These results suggest ways to decrease salespersons' role stress by ensuring an optimal level of the number of accounts and brand strength.

Analysis of Radiation Dose Enhancement for Spread Out Bragg-peak of Proton (확산된 피크의 양성자에서 선량 증강 현상에 대한 분석)

  • Hwang, Chulhwan;Kim, JungHoon
    • Journal of the Korean Society of Radiology
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    • v.13 no.2
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    • pp.253-260
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    • 2019
  • Radiation dose enhancement is a method of increasing the cross section of interaction, thus increasing the deposited dose. This can contribute to linear energy transfer, LET and relative biological effectiveness, RBE. Previous studies on dose enhancement have been mainly focused on X, ${\gamma}-rays$, but in this study, the dose enhancement was analyzed for proton using Monte Carlo simulation using MCNP6. Based on the mathematical modeling method, energy spectrum and relative intensity of spread out Bragg-peak were calculated, and evaluated dose enhancement factor and dose distribution of dose enhancement material, such as aurum and gadolinium. Dose enhancement factor of 1.085-1.120 folds in aurum, 1.047-1.091 folds in gadolinium was shown. In addition, it showed a decrease of 95% modulation range and practical range. This may lead to an uncertain dose in the tumor tissue as well as dose enhancement. Therefore, it is necessary to make appropriate corrections for spread out Bragg-peak and practical range from mass stopping power. It is expected that Monte Carlo simulation for dose enhancement will be used as basic data for in-vivo and in-vitro experiments.

Development of a Dynamic Downscaling Method using a General Circulation Model (CCSM3) of the Regional Climate Model (MM5) (전지구 모델(CCSM3)을 이용한 지역기후 모델(MM5)의 역학적 상세화 기법 개발)

  • Choi, Jin-Young;Song, Chang-Geun;Lee, Jae-Bum;Hong, Sung-Chul;Bang, Cheol-Han
    • Journal of Climate Change Research
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    • v.2 no.2
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    • pp.79-91
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    • 2011
  • In order to study interactions between climate change and air quality, a modeling system including the downscaling scheme has been developed in the integrated manner. This research focuses on the development of a downscaling method to utilize CCSM3 outputs as the initial and boundary conditions for the regional climate model, MM5. Horizontal/vertical interpolation was performed to convert from the latitude/longitude and hybrid-vertical coordinate for the CCSM3 model to the Lambert-Conformal Arakawa-B and sigma-vertical coordinate for the MM5 model. A variable diagnosis was made to link between different variables and their units of CCSM and MM5. To evaluate the dynamic downscaling performance of this study, spatial distributions were compared between outputs of CCSM/MM5 and NRA/MM5 and statistic analysis was conducted. Temperature and precipitation patterns of CCSM/MM5 in summer and winter showed a similar pattern with those of observation data in East Asia and the Korean Peninsula. In addition, statistical analysis presented that the agreement index (AI) is more than 0.9 and correlation coefficient about 0.9. Those results indicate that the dynamic downscaling system built in this study can be used for the research of interaction between climate change and air quality.

A study on the estimation of wind noise level using the measured wind-speed data in the coastal area of the East Sea (동해 연안에서 관측된 풍속자료를 이용한 바람소음준위 추정 연구)

  • Park, Jisung;Kang, Donghyug;Kim, Mira;Cho, Sungho
    • The Journal of the Acoustical Society of Korea
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    • v.38 no.4
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    • pp.378-386
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    • 2019
  • Unlike ship noise that radiates from moving ships, wind noise is caused by breaking waves as a result of the interaction between the wind and the sea surface. In this paper, WNL (Wind Noise Level) was modeled by considering the noise source of the wind as the bubble cloud generated by the breaking waves. In the modeling, SL( Source Level) of the wind noise was calculated using the wind-speed data measured from the weather buoy operated in the coastal area of the East Sea. At the same time as observing the wind speed, NL (Noise Level) was continuously measured using a self-recording hydrophone deployed near the weather buoy. The modeled WNL according to the wind speed and the measured NL removing the shipping noise from the acoustic raw data were compared in the low-frequency band. The overall trends between the modeled WNL and the measured NL were similar to each other. Therefore, it was confirmed that it is possible to model the WNL in the shallow water considering the SL and distribution depth of bubble cloud caused by the wind.

Analysis of Changes in Urban Spatial Structure for Balanced Urban Development (도시균형발전을 위한 도시공간구조 변화 진단)

  • KIM, Ho-Yong
    • Journal of the Korean Association of Geographic Information Studies
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    • v.24 no.2
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    • pp.40-51
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    • 2021
  • The purpose of this study is to diagnose urban spatial structures using spatial modeling techniques for balanced urban development as part of sustainable urban growth management. Since urban spatial structure is an interaction of various activities, it is necessary to interpret the analysis results in conjunction with the analysis of changes in spatial structural elements. In this study, population and transportation were approached for research purposes. Population data were applied to the Getis-Ord Gi* method, a spatial statistical technique, to analyze the concentration-decreasing region of the population. Traffic data analyzed the trend of centrality change by applying commuting traffic O-D data to Social Network Analysis techniques. The analysis showed that urban imbalance was growing, and the centrality of transportation was changing. The results of the analysis of spatial structure elements could be interpreted by linking the results of each factor to each neighborhood unit, predicting changes in urban spatial structure and suggesting directions for sustainable urban growth management.These results could also be used as a decision-making tool for various urban growth management policies introduced to cope with rapid urban development and uncontrollable development in many cities around the world.

Systematic Target Screening Revealed That Tif302 Could Be an Off-Target of the Antifungal Terbinafine in Fission Yeast

  • Lee, Sol;Nam, Miyoung;Lee, Ah-Reum;Lee, Jaewoong;Woo, Jihye;Kang, Nam Sook;Balupuri, Anand;Lee, Minho;Kim, Seon-Young;Ro, Hyunju;Choi, Youn-Woong;Kim, Dong-Uk;Hoe, Kwang-Lae
    • Biomolecules & Therapeutics
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    • v.29 no.2
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    • pp.234-247
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    • 2021
  • We used a heterozygous gene deletion library of fission yeasts comprising all essential and non-essential genes for a microarray screening of target genes of the antifungal terbinafine, which inhibits ergosterol synthesis via the Erg1 enzyme. We identified 14 heterozygous strains corresponding to 10 non-essential [7 ribosomal-protein (RP) coding genes, spt7, spt20, and elp2] and 4 essential genes (tif302, rpl2501, rpl31, and erg1). Expectedly, their erg1 mRNA and protein levels had decreased compared to the control strain SP286. When we studied the action mechanism of the non-essential target genes using cognate haploid deletion strains, knockout of SAGA-subunit genes caused a down-regulation in erg1 transcription compared to the control strain ED668. However, knockout of RP genes conferred no susceptibility to ergosterol-targeting antifungals. Surprisingly, the RP genes participated in the erg1 transcription as components of repressor complexes as observed in a comparison analysis of the experimental ratio of erg1 mRNA. To understand the action mechanism of the interaction between the drug and the novel essential target genes, we performed isobologram assays with terbinafine and econazole (or cycloheximide). Terbinafine susceptibility of the tif302 heterozygous strain was attributed to both decreased erg1 mRNA levels and inhibition of translation. Moreover, Tif302 was required for efficacy of both terbinafine and cycloheximide. Based on a molecular modeling analysis, terbinafine could directly bind to Tif302 in yeasts, suggesting Tif302 as a potential off-target of terbinafine. In conclusion, this genome-wide screening system can be harnessed for the identification and characterization of target genes under any condition of interest.

A modeling study of the process of change to a totalitarian state : The Last Man and Venezuela (전체주의 국가로의 변화과정에 대한 모형화 연구 : 최후의 인간과 베네수엘라)

  • Yoon, Hyeongho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.12
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    • pp.709-718
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    • 2020
  • Even after Fukuyama declared "The End of History" in 1989, the challenge to liberal democracy continues. Controversy about totalitarianism is constantly being raised both internally and externally in democratic countries and leaders, as well as the US-China war of supremacy. In this paper, I explored a hypothesis about the totalitarian process, and to explain this hypothesis, I analyzed the case of Venezuela, which was once referred to as a welfare model state. This paper presupposes Fukuyama's insistence on the universality of liberal democracy but considers the last man Nietzsche argues for the last man he assumes. Accordingly, the process of totalitarianism was viewed as a process in which totalitarianism was institutionalized and spread internationally through the linkage and interaction of the last fallen humans, the masses, and totalitarians in the international and domestic environments. According to this hypothesis, the Bol?var Revolution and Chavez show the process of transformation into a typical quasi-totalism. Although the Venezuelan people preferred democracy, they remained the last man who had become a man of "rich consciousness." While investigating this hypothesis, it was confirmed that extensive and interdisciplinary studies such as digital t otalitarianism and the development of science and technology should be followed.