• The Korean Journal of Pain
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• 제24권1호
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• pp.22-30
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• 2011

Background: Pregabalin has been shown to have analgesic effect in acute pain models. The primary objective was to examine the efficacy a single dose of pregabalin, would have on morphine consumption following lumbar discectomy. Methods: With ethical approval a randomized, placebo-controlled prospective trial was undertaken in 32 patients (ASA I-II, 18-65 years) with radicular low back pain for > 3 months undergoing elective lumbar discectomy. Patients received either oral pregabalin 300 mg (PG Group) or placebo (C Group) one hour before surgery. Pain intensity, the accumulative morphine consumption and adverse effects were recorded for 24 hours following surgery. Functional, psychological and quantitative sensory testing were also assessed. Results: Fourteen patients out of the 32 recruited were randomized to receive pregabalin. Morphine consumption was reduced (absolute difference of 42.3%) between groups with medium effect size. (Mann-Whitney; U =52.5, z-score= 2.84, P = 0.004, r = 0.14). This was not associated with a significant difference in the incidence of adverse effects between the two groups. The median pain intensity (VAS) on movement was not significantly different between groups. Conclusions: A single pre-operative dose of pregabalin (300 mg) did not result in a reduction in pain intensity compared to placebo in this patient cohort but the significant reduction in morphine consumption suggests that a fixed peri-operative dosing regime warrants investigation.

• 한국소음진동공학회논문집
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• 제11권4호
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• pp.22-30
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• 2001

In this paper, active control of vibrational intensity at a reference point in an infinite, elastic plate was discussed. The plate is excised harmonically by a vibrating source, which has a vertical point force. The optimal condition of controller was investigated to minimize the vibrational intensity being transmitted from the vibrating source to a reference point. Hence the method of feedforward control was employed for the control strategy and then the cost function was evaluated to find the optimal control force. Three types of control force (Vertical force, Moment, and Coupling force (a set of vertical force and moment) ) and controller's positions were examined to define the optimal condition of the controller. The vibrational intensity at a reference point was found to be reduced down to a zero level, compared with the uncontrolled case. Especially maximum reduction of vibrational intensity was achieved when the controller was collinearly positioned between a vibrating source and a reference point.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2003년도 추계학술대회논문집
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• pp.333-337
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• 2003

The use of reactive shearing structural intensity to place small patches of constrained layer damping material in order to achieve the largest reduction in the radiated sound power of Air-conditioner outdoor unit is described. The normal surface velocity of each panel was measured using a laser doppler vibrometer. Experimental results indicated that patches of constrained layer damping material placed over areas of high reactive structural intensity reduced the radiated sound power significantly more than patches of the same area placed over areas of low reactive structural intensity

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2012년도 추계학술대회 논문집
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• pp.251-255
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• 2012

Structural intensity has been mainly utilized to identify vibration energy flow in a vessel. In this paper, the structural intensity of a shuttle tanker subjected to H-moment of the main engine was calculated using a finite element model. From the analysis, it was found that the top-bracing elements, which support the main engine onto the hull structure to prevent the excessive transverse vibration of the main engine, play the role of the dominant path and sink for vibration energy flow from the main engine. Therefore, the structural intensity was controlled by the modification of stiffness and damping characteristics of the top-bracing elements. As a result, it is observed that the transverse vibration level at the center of navigation bridge deck decreased after the control of structural intensity.

• 식품과학과 산업
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• 제49권3호
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• pp.29-39
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• 2016

Recently, due to the cognition that obesity is the cause of adult diseases, interests of consumers in low-sugar and low-calorie foods are growing more and more. While various policies are being implemented to reduce sugar contents in processed foods, the reduced sweetness caused by lesser sugar content is complemented by using high-intensity sweeteners. Some of the typical high-intensity sweeteners are sucralose, aspartame, acesulfame potassium and stevia, etc. Since the relative sweetness degree, sweetness profile, and physical properties of these sweeteners should be different from one another, it is important that all these characteristics are well-understood before applying them. Thus, the objective of this study is to introduce the properties and applications of high-intensity sweeteners in order to reduce sugar content of processed foods.

• Parasites, Hosts and Diseases
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• 제58권4호
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• pp.421-430
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• 2020

This study aimed to investigate whether mass drug administration (MDA) intervention has an equivalent effect on reducing the prevalence and intensity of Schistosoma haematobium infection regardless of the baseline values. A repeated cross-sectional survey was performed targeting students of 12 primary schools in Al Jabalain and El Salam districts of White Nile State, Sudan, at both 1 week before and 8 months after the MDA. Prior to the baseline survey, schoolaged children in Al Jabalain had received MDA interventions twice in 4 years, while those in El Salam had not. The baseline prevalence was 9.1% in Al Jabalain and 35.2% in El Salam, which were reduced to 1.8% and 5.5% at 8 months after the MDA, respectively. The corresponding reduction rates were 80.3% and 84.4%, not significant difference between both districts. However, changes in the geometric mean intensity (GMI) of egg counts were significantly different between both districts. The baseline GMIs were 14.5 eggs per 10 ml of urine (EP10) in Al Jabalain and 18.5 EP10 in El Salam, which were reduced to 7.1 and 11.2 EP10 after treatment, respectively. The corresponding reduction rates were 51.0% and 39.5%. In conclusion, MDA interventions were found to bring about similar relative reduction in prevalence regardless of the baseline value; however, the relative reduction in infection intensity was more salient in the district with a low baseline value for both prevalence and intensity. This clearly points to the importance of repeated MDA interventions in endemic areas, which will eventually contribute to schistosomiasis elimination.

• 한국환경복원기술학회지
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• 제22권6호
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• pp.115-124
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• 2019

In a climate change environment where heat damage and drought occur during a rainy season such as in 2018, a vegetation-based LID system that enables disaster prevention as well as environment improvement is suggested in lieu of an installation-type LID system that is limited to the prevention of floods. However, the quantification of its performance as against construction cost is limited. This study aims to present an experiment environment and evaluation method on quantitative performance, which is required in order to disseminate the vegetation-based LID system. To this end, a 3^rd quartile huff time distribution mass curve was generated for 20-year frequency, 60-minute probable rainfall of 68mm/hr in Cheonan, and effluent was analyzed by recreating artificial rainfall. In order to assess the reliability of the rainfall event simulator, 10 repeat tests were conducted at one-minute intervals for 20 minutes with minimum rainfall intensity of 22.29mm/hr and the maximum rainfall intensity of 140.69mm/hr from the calculated probable rainfall. Effective rainfall as against influent flow was 21.83mm/hr (sd=0.17~1.36, n=20) on average at the minimum rainfall intensity and 142.27mm/hr (sd=1.02~3.25, n=20) on average at the maximum rainfall intensity. In artificial rainfall recreation experiments repeated for three times, the most frequent quartile was found to be the third quartile, which is around 40 minutes after beginning the experiment. The peak flow was observed 70 minutes after beginning the experiment in the experiment zone and after 50 minutes in the control zone. While the control zone recorded the maximum runoff intensity of 2.26mm/min(sd=0.25) 50 minutes after beginning the experiment, the experiment zone recorded the maximum runoff intensity of 0.77mm/min (sd=0.15) 70 minutes after beginning the experiment, which is 20 minutes later than the control zone. Also, the maximum runoff intensity of the experiment zone was 79.6% lower than that of the control zone, which confirmed that vegetation unit-type LID system had rainfall runoff reduction and delay effects. Based on the above findings, the reliability of a lab-level rainfall simulator for monitoring the vegetation-based LID system was reviewed, and maximum runoff intensity reduction and runoff time delay were confirmed. As a result, the study presented a performance evaluation method that can be applied to the pre-design of the vegetation-based LID system for rainfall events on a location before construction.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2023년도 학술발표회
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• pp.170-170
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• 2023

Providing safe and readily available water is vital to maintain public health. One of the most prevalent methods to prevent the spread of waterborne diseases is applying chlorine injection to the treated water before distribution. During the water transmission and distribution, the chlorine will experience a reduction, which can imply potential risks for human health if it falls below the minimum threshold. The ability to determine the appropriate initial intensity of chlorine at the source would be significant to prevent such problems. This study proposes two methods that integrate hydraulic and water quality modeling to determine the suitable intensity of chlorine to be injected into the source water to maintain the minimum chlorine concentration (e.g., 0.2 mg/l) at each demand node. The water quality modeling employs the first-order decay to estimate the rate of chlorine reduction in the water. The first method utilizes a backtracking algorithm to trace the path of water from the demand node to the source during each time step, which helps to accurately determine the travel time through each pipe and node and facilitate the computation of time-dependent chlorine decay in the water delivery process. However, as a backtracking algorithm is computationally intensive, this study also explores an alternative approach using a water age. This approach estimates the elapsed time of water delivery from the source to the demand node and calculate the time-dependent reduction of chlorine in the water. Finally, this study compares the outcomes of two approaches and determines the suitable and effective method for calculating the chlorine intensity at the source to maintain the minimum chlorine level at demand nodes.

• International Journal of Automotive Technology
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• 제6권3호
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• pp.293-303
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• 2005

Bonded dissimilar materials are being increasingly used in automobiles, aircraft, rolling stocks, electronic devices and engineering structures. Bonded dissimilar materials have several material advantages over homogeneous materials such as high strength, high reliability, light weight and vibration reduction. Due to their increased use it is necessary to understand how these materials behave under stress conditions. One important area is the analysis of the stress intensity factors for interface cracks emanating from circular holes in bonded dissimilar materials. In this study, the bonded scarf joint is selected for analysis using a model which has comprehensive mixed-mode components. The stress intensity factors were determined by using the boundary element method (BEM) on the interface cracks. Variations of scarf angles and crack lengths emanating from a centered circular hole and an edged semicircular hole in the Al/Epoxy bonded scarf joints of dissimilar materials are computed. From these results, the stress intensity factor calculations are verified. In addition, the relationship between scarf angle variation and the effect by crack length and holes are discussed.

• 한국정밀공학회지
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• 제19권6호
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• pp.109-118
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• 2002

The vibrational intensity and the dynamic response of a compound vibratory system had been controlled actively by means of a feedforward control method. A compound vibratory system consists of a flexible beam and two discrete systems - a vibrating source and a dynamic absorber. By considering the interactive motions between discrete systems and a flexible beam, the equations of motion for a compound vibratory system were derived using a method of variation of parameters. To define the optimal conditions of a controller the cost function, which denotes a time averaged power flow, was evaluated numerically. The possibility of reductions of both of vibrational intensity and dynamic response at a control point located at a distance from a source were fecund to depend on the positions of a source, a control point and a controller. Especially the presence of a dynamic absorber gives the more reduction on the dynamic response but the less on the vibrational intensity than those without a dynamic absorber.