• Title/Summary/Keyword: Intensity Analysis

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Scoring System to Predict Malignancy for MRI-Detected Lesions in Breast Cancer Patients: Diagnostic Performance and Effect on Second-Look Ultrasonography (유방암 환자의 MRI에서 발견된 병변의 악성 예측을 위한 점수체계: 진단적 능력과 이차 초음파 결정에 미치는 영향)

  • Young Geol Kwon;Ah Young Park
    • Journal of the Korean Society of Radiology
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    • v.81 no.2
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    • pp.379-394
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    • 2020
  • Purpose To design a scoring system to predict malignancy of additional MRI-detected lesions in breast cancer patients. Materials and Methods Eighty-six lesions (64 benign and 22 malignant) detected on preoperative MRI of 68 breast cancer patients were retrospectively included. The clinico-radiologic features were correlated with the histopathologic results using the Student's t-test, Fisher's exact test, and logistic regression analysis. The scoring system was designed based on the significant predictive features of malignancy, and its diagnostic performance was compared with that of the Breast Imaging-Reporting and Data System (BI-RADS) category. Results Lesion size ≥ 8 mm (p < 0.001), location in the same quadrant as the primary cancer (p = 0.005), delayed plateau kinetics (p = 0.010), T2 isointense (p = 0.034) and hypointense (p = 0.024) signals, and irregular mass shape (p = 0.028) were associated with malignancy. In comparison with the BI-RADS category, the scoring system based on these features with suspicious non-mass internal enhancement increased the diagnostic performance (area under the receiver operating characteristic curve: 0.918 vs. 0.727) and detected three false-negative cases. With this scoring system, 22 second-look ultrasound examinations (22/66, 33.3%) could have been avoided. Conclusion The scoring system based on the lesion size, location relative to the primary cancer, delayed kinetic features, T2 signal intensity, mass shape, and non-mass internal enhancement can provide a more accurate approach to evaluate MRI-detected lesions in breast cancer patients.

Importance of an Integrated Assessment of Functional Disability and Work Ability in Workers Affected by Low Back Pain

  • Fabrizio Russo;Cristina Di Tecco;Simone Russo;Giorgia Petrucci;Gianluca Vadala;Vincenzo Denaro;Sergio Iavicoli
    • Safety and Health at Work
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    • v.15 no.1
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    • pp.66-72
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    • 2024
  • Background: This study examines the relationship between functional disability and work ability in workers affected by low back pain (LBP) through an analysis of correlations between the Oswestry Disability Index (ODI) and Work Ability Index (WAI). The role of personal and work factors on functional disability/work ability levels has also been studied. LBP is the most common musculoskeletal problem and a major disabling health problem worldwide. Its etiology is multifactorial. Multidisciplinary approaches may help reduce the burden of pain and disability and improve job continuity and reintegration at work. Methods: A cohort of 264 patients affected by LBP from an Italian outpatient clinic were included in a clinical diagnostic/therapeutic trial aiming at rehabilitation and return to work through an integrated investigation protocol. Data were collected during the first medical examination using anamnestic and clinical tools. The final sample is composed of 252 patients, 57.1% man, 44.0 % blue collars, 46.4% with the high school degree, 45.6% married. Results: WAI and ODI reported a negative and fair correlation (r = -0.454; p = .000). Workers with acute LBP symptoms have a higher probability of severe disability than those with chronic LBP symptoms. White collars without depressive symptoms reported higher work ability - even in chronic disability conditions-than those with depressive symptoms. Conclusion: The study found that ODI and WAI have a convergent validity and this suggests that the two tools measure capture distinctive aspects of disability related to personal, environmental, and occupational characteristics. The most important and modifiable prognostic factors found for ODI and WAI were depressive symptoms, workday absence, and intensity of back pain. The study also found a mild association between age and ODI. The study's findings highlight the importance of using a multidisciplinary approach to manage and prevent disability due to LBP.

Development and Verification of Muscle Strength Effectiveness Based on Fitsig® (EMG Prototype)

  • Changjin Ji;Yong-hyun Byun;Sangho Kim
    • Journal of the Korea Society of Computer and Information
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    • v.29 no.5
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    • pp.111-121
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    • 2024
  • With strength training comes the risk of injury and the benefits of exercise. Lack of knowledge and experience or repetitions at excessive intensity can lead to injury. Adequate feedback on an exercise's progress can increase the exercise's effectiveness and reduce injuries by providing scientific data and psychological motivation. This study aimed to validate EMG equipment and examine the effects of 8 weeks of biofeedback training with wireless electromyography. A correlation analysis between the Noraxon device and Fitsig®(EMG Prototype), a well-known instrument in the field of research, showed a moderate correlation. Statistically significant differences in humeral circumference, humeral muscle mass, and biceps and triceps strength were found between the left and right sides of the body over time, with no differences in the type of exercise. Feedback training with real-time EMG was found to be favorable for hypertrophic growth and strength improvement. Future studies should be conducted to investigate its application in sports activities further.

Quantitative Thoracic Magnetic Resonance Criteria for the Differentiation of Cysts from Solid Masses in the Anterior Mediastinum

  • Eui Jin Hwang;MunYoung Paek;Soon Ho Yoon;Jihang Kim;Ho Yun Lee;Jin Mo Goo;Hyungjin Kim;Heekyung Kim;Jeanne B. Ackman
    • Korean Journal of Radiology
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    • v.20 no.5
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    • pp.854-861
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    • 2019
  • Objective: To evaluate quantitative magnetic resonance imaging (MRI) parameters for differentiation of cysts from and solid masses in the anterior mediastinum. Materials and Methods: The development dataset included 18 patients from two institutions with pathologically-proven cysts (n = 6) and solid masses (n = 12) in the anterior mediastinum. We measured the maximum diameter, normalized T1 and T2 signal intensity (nT1 and nT2), normalized apparent diffusion coefficient (nADC), and relative enhancement ratio (RER) of each lesion. RERs were obtained by non-rigid registration and subtraction of precontrast and postcontrast T1-weighted images. Differentiation criteria between cysts and solid masses were identified based on receiver operating characteristics analysis. For validation, two separate datasets were utilized: 15 patients with 8 cysts and 7 solid masses from another institution (validation dataset 1); and 11 patients with clinically diagnosed cysts stable for more than two years (validation dataset 2). Sensitivity and specificity were calculated from the validation datasets. Results: nT2, nADC, and RER significantly differed between cysts and solid masses (p = 0.032, 0.013, and < 0.001, respectively). The following criteria differentiated cysts from solid masses: RER < 26.1%; nADC > 0.63; nT2 > 0.39. In validation dataset 1, the sensitivity of the RER, nADC, and nT2 criteria was 87.5%, 100%, and 75.0%, and the specificity was 100%, 40.0%, and 57.4%, respectively. In validation dataset 2, the sensitivity of the RER, nADC, and nT2 criteria was 90.9%, 90.9%, and 72.7%, respectively. Conclusion: Quantitative MRI criteria using nT2, nADC, and particularly RER can assist differentiation of cysts from solid masses in the anterior mediastinum.

Classification of latent classes and analysis of influencing factors on longitudinal changes in middle school students' mathematics interest and achievement: Using multivariate growth mixture model (중학생들의 수학 흥미와 성취도의 종단적 변화에 따른 잠재집단 분류 및 영향요인 탐색: 다변량 성장혼합모형을 이용하여)

  • Rae Yeong Kim;Sooyun Han
    • The Mathematical Education
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    • v.63 no.1
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    • pp.19-33
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    • 2024
  • This study investigates longitudinal patterns in middle school students' mathematics interest and achievement using panel data from the 4th to 6th year of the Gyeonggi Education Panel Study. Results from the multivariate growth mixture model confirmed the existence of heterogeneous characteristics in the longitudinal trajectory of students' mathematics interest and achievement. Students were classified into four latent classes: a low-level class with weak interest and achievement, a high-level class with strong interest and achievement, a middlelevel-increasing class where interest and achievement rise with grade, and a middle-level-decreasing class where interest and achievement decline with grade. Each class exhibited distinct patterns in the change of interest and achievement. Moreover, an examination of the correlation between intercepts and slopes in the multivariate growth mixture model reveals a positive association between interest and achievement with respect to their initial values and growth rates. We further explore predictive variables influencing latent class assignment. The results indicated that students' educational ambition and time spent on private education positively affect mathematics interest and achievement, and the influence of prior learning varies based on its intensity. The perceived instruction method significantly impacts latent class assignment: teacher-centered instruction increases the likelihood of belonging to higher-level classes, while learner-centered instruction increases the likelihood of belonging to lower-level classes. This study has significant implications as it presents a new method for analyzing the longitudinal patterns of students' characteristics in mathematics education through the application of the multivariate growth mixture model.

Improvement of the Thinning System by Exploring the Stand Density Management Criteria for Chamaecyparis obtusa in South Korea (편백림의 임분밀도 관리 기준 탐색을 통한 시업체계 개선)

  • Su Young Jung;Kwang Soo Lee;Hyun Soo Kim;Joon Hyung Park
    • Journal of Korean Society of Forest Science
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    • v.113 no.1
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    • pp.131-142
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    • 2024
  • The purpose of this study was to estimate the optimal stand density criteria for each growth stage of Chamaecyparis obtusa (Siebold & Zucc.) Endl. to achieve the timber production goal for cypress forests and develop an optimal silvicultural system for forest thinning. A relative yield index (Ry) value of 0.75, presented as a stand density management criterion index, was estimated by analyzing the relationship characteristics between the composition ratio and stand density of slender trees from 216 sample plots of the recruited cypress forests. The analysis of the feasibility of achieving each production target in the existing silvicultural system for C. obtusa revealed that the growth rate according to the parameters of forest land productivity, such as site index and thinning intensity according to the increase in age, was not properly reflected. In the thinning system for each timber production target analyzed in this study, 353 high-quality large hardwoods from 498.1 m3/ha, 703 high-quality medium hardwoods from 376.2 m3/ha, and 1,758 small-diameter hardwoods from 249.5 m3/ha could be harvested. Although the silvicultural system prepared on the basis of the results of this study cannot be uniformly applied according to various management goals, this study is meaningful in that it presents empirical reference standards based on the stand density management diagram that reflects the growth characteristics of cypress forests in South Korea.

The effect of R&D investment in Chinese private firms on firm performance and value: The moderating effect of ESG score (중국 민영기업의 R&D 투자가 경영성과와 기업가치에 미치는 영향: ESG 성과지수의 조절효과)

  • Youngsoo Park
    • Analyses & Alternatives
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    • v.8 no.2
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    • pp.87-115
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    • 2024
  • This study examines the effect of R&D investment on firm performance and value of Chinese private firms. Through R&D investment, firms aim to acquire knowledge and technological resources to create innovation and competitive advantage, which ultimately enhances firm performance and value. However, unlike other investments, R&D investments are characterized by high adjustment costs and risks, uncertainty and asymmetric information. In addition, the effect of R&D investment on firm performance and value has been shown to be mixed results due to various internal and external contextual factors. Therefore, this study intends to consider how the ESG activities of firms, which have recently attracted attention, act as a contextual factor in the results of R&D investment. This is because interaction with stakeholders through ESG activities is considered to be an important factor in securing competitive advantages and sustainable growth. In this context, this study measures the effect of a firm's R&D investment on its business performance by dividing it into financial performance and value, respectively, and examines the moderating effect of ESG score on the relationship. Based on empirical analysis of all Chinese private firms from 2010 to 2019, the results show that a firm's R&D investment has a negative impact on performance and a positive impact on value. Furthermore, a high ESG score of private firms positively moderates each relationship, emphasizing the importance of ESG activities.

A study on algal bloom forecast system based on hydro-meteorological factors in the mainstream of Nakdong river using machine learning (머신러닝를 이용한 낙동강 본류 구간 수문-기상인자 조류 예보체계 연구)

  • Taewoo Lee;Soojun Kim;Junhyeong Lee;Kyunghun Kim;Hoyong Lee;Duckgil Kim
    • Journal of Wetlands Research
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    • v.26 no.3
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    • pp.245-253
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    • 2024
  • Blue-green algal bloom, or harmful algal bloom has a negative impact on the aquatic ecosystem and purified water supply system due to oxygen depletion in the water body, odor, and secretion of toxic substances in the freshwater ecosystem. This Blue-green algal bloom is expected to increase in intensity and frequency due to the increase in algae's residence time in the water body after the construction of the Nakdong River weir, as well as the increase in surface temperature due to climate change. In this study, in order to respond to the expected increase in green algae phenomenon, an algal bloom forecast system based on hydro-meteorological factors was presented for preemptive response before issuing a algal bloom warning. Through polyserial correlation analysis, the preceding influence periods of temperature and discharge according to the algal bloom forecast level were derived. Using the decision tree classification, a machine learning technique, Classification models for the algal bloom forecast levels based on temperature and discharge of the preceding period were derived. And a algal bloom forecast system based on hydro-meteorological factors was derived based on the results of the decision tree classification models. The proposed algae forecast system based on hydro-meteorological factors can be used as basic research for preemptive response before blue-green algal blooms.

Analysis of Parameter Optimization Reflecting the Characteristics of Runoff in Small Mountain Catchment (소규모 산지 유역의 유출특성을 반영한 매개변수 최적화 분석)

  • Joungsung Lim;Hojin Lee
    • Journal of the Korean GEO-environmental Society
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    • v.25 no.9
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    • pp.5-14
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    • 2024
  • In Korea, torrential rain frequency and intensity have surged over the past five years (2019-2023), breaking rainfall records. Due to insufficient observation facilities for rainfall and runoff data in small mountainous catchments, preparing for unexpected floods is challenging. This study examines the Bidogyo catchment in Goesan-gun, Chungcheongbuk-do, comparing design flood discharge calculated with optimized parameters versus standard guidelines. Using HEC-HMS and Q-GIS for model construction, five rainfall events were analyzed with data from the National Water Resources Management Information System. The time of concentration (Tc) and storage constant (K) were calculated using the Seokyeongdae formula and model optimization. Results showed that optimized parameters produced higher objective function values for flood events. The design flood discharge varied by -10.7% to 17.3% from the standard guidelines when using optimized parameters. Moreover, optimized parameters yielded flood discharges closer to observed values, highlighting limitations of the Seokyeongdae formula for all catchments. Further research aims to develop suitable parameter estimation methods for small mountainous catchments in Korea.

Effect of a 12-Week Combined Exercise Program on Cardiovascular Function and Electrocardiogram Based ST Segment, QRS in Obese Middle-Aged Women (12주 복합운동 프로그램이 비만 중년여성의 심혈관계 기능과 심전도 기반의 ST 분절, QRS군에 미치는 영향)

  • Jeong-Hee Yun;Ki-Wook Jo;Chang-Hwan Kim
    • Journal of the Korean Applied Science and Technology
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    • v.41 no.3
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    • pp.705-720
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    • 2024
  • This study randomly assigned 24 middle-aged women to determine the effect of a 12-week combined exercise program on cardiovascular function and electrocardiogram-based ST segment and QRS in obese middle-aged women. Analysis of the results was conducted to verify differences within groups and between periods and groups. In terms of cardiovascular function, myocardial oxygen consumption showed a significant decrease in the experimental group during the resting phase and the highest intensity phase during exercise, and an interaction between group and period at rest was also observed. The heart rate recovery rate showed a significant decrease in the experimental group at 2 minutes of recovery, while in the control group, on the contrary, a significant increase was observed. The experimental group showed a significant decrease in systolic blood pressure, and an interaction between group and period was also observed. There was no change in diastolic blood pressure in both the experimental and control groups, and there was a statistically significant decrease in pulse pressure only in the experimental group at the 3-minute recovery stage. In the case of the electrocardiogram, the QRS height in the experimental group showed a significant increase in most cases at rest and at 3, 6, and 9 minutes during the recovery period, while there was no significant difference in the QRS period in both the experimental and control groups, and the ST segment height was significantly increased at rest in the experimental group. appeared to have increased. Therefore, summarizing the results of this study, it is believed that the 12-week combined exercise program has a positive effect in improving cardiovascular function, ventricular contractility in electrocardiograms, and myocardial ischemia in obese middle-aged women.