• Title/Summary/Keyword: Integrative Model

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Effects of Protease Treatment and Animal Behavior on the Dissociative Culture of Aplysia Neurons

  • Lee, Nuribalhae;Rim, Young-Soo;Kaang, Bong-Kiun
    • Animal cells and systems
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    • v.13 no.3
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    • pp.267-274
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    • 2009
  • The dissociative culture technique of Aplysia neuron is one of the key methods that have been used for studies of cellular and molecular mechanisms of neuronal functioning. However, despite the advantages this method offers as an experimental model, its technical efficiency has had room for improvement. In this study, we examined certain putative factors that might affect the culture quality. The effects of neuronal damage induced by physical injuries, heat shock, and surface protein degradation were evaluated along with the correlation between the culture quality and animal behavior. As a result, we found that physical injury can be a critical factor that affects culture quality, whereas the heat shock and surface protein degradation had negligible effect on it. In addition, we discovered that siphon retraction time was not a good measurement for healthy neurons. Based on these findings, we suggest here an improved method in which the degree of physical injury is reduced by means of multiple protease treatment.

Causal Loop Diagrams Model of IT Professionals' Happiness : Through System Dynamics Analysis Approach (IT 전문가 행복 인과관계 다이어그램 모형 : 시스템 다이내믹스 분석 접근법으로)

  • Chang, Yun Hi
    • Journal of Internet Computing and Services
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    • v.17 no.4
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    • pp.161-172
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    • 2016
  • The following research investigates core factors required for IT professionals to achieve and remain happy on their jobs through dynamic and structural CLD and suggests personal, organizational, and government level (happiness) promoting factors. Researcher adopted the system dynamics methodology which is qualitative research techniques pursue behavior probability by using CLD. It spotlights 6 CLD: job satisfaction, organizational commitment, positive sensitivity, negative sensitivity, amicable relationship, job sustainment intention, in addition to numerous factors that affect them from an integrative perspective. It differentiates itself from one-way relationship focused qualitative research to an advanced mutual and realistic perspective exploratory research.

A Basic Study on the Exhibition Design of a Science Museum -Focus on the Case Study on Exhibition System & Prestutation Method of a Museum of Telecommunication- (이공계박물관의 전시디자인에 관한 기초적 연구 -정보통신 박물관의 전시체계와 연출방법에 관한 사례연구를 중심으로-)

  • 김종훈;임채진
    • Korean Institute of Interior Design Journal
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    • no.10
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    • pp.58-68
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    • 1997
  • The core of character and concept in an exhibition space of contemporary museum is that the place for relics and materials changes into the place for spectators, the static exhibition place changes into the dynamic exhibition place, and the place for learning naturally during amusement. In other words, it could convey the conceptual exhibition object which is not the material object called a relic, it could be a place where is to investigate, participate, experience and enjoy with easily method to general public, and ordinary people are supposed to experience with integrative the world of intellectual, cultural and artistic which is inconcionsly rising a dimensiov. In order to response positively the change of these exhibition concept itself, exhibition system will be established through the analysis of realistic exhibition objects with the visulatization of theme or thought of an exhibitiov. In process of conveying image, the effective and concrete exhibition method and technique should be measured in order to realize the communication between spectators and exhibition objects. The purpose of this study is to find the methodology which is enable to establish the exhibition theme and presentation system through the selection and analysis of exhibition objects in major cases of a musem of ecience and engneering, to find the process model till the methodology applies to the space scheme, and to find finally the designed indicators which is applicable to the progress of exhibition desigv.

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Delphi Study about Mathematics Gifted Education Based on STEAM Education (수학영재를 위한 STEAM교육 방안 마련을 위한 델파이 조사)

  • Paik, Heesu
    • School Mathematics
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    • v.15 no.4
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    • pp.867-888
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    • 2013
  • The purpose of this paper was to investigate mathematics gifted educational methods based on STEAM education by Delphi study. As a result by total 3 round Delphi method, the concept of STEAM education for mathematics gifted students was education of developing capacity of Holistic Growth that can communicate diverse people through self-monitoring study as they can find and solve problems with integrative thinking and creative thinking. Thus this elicited the consensual agreements of experts about mathematics gifted educational goals, methods, contents, and evaluations etc. As a follow-up research will be developed mathematics gifted educational model based on STEAM education.

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Population Biology of Korean Pomfret Pampus echinogaster (Basilewsky, 1855) (Perciformes: Stromateidae) on the Western Coast of Korea, Yellow Sea

  • Oh, Chul-Woong;Na, Jong-Hun;Kim, Jin-Koo
    • Animal cells and systems
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    • v.13 no.1
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    • pp.83-89
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    • 2009
  • Investigations were made on population biology of Pampus echinogaster (Basilewsky, 1855) in the coastal areas of Korea, Yellow Sea, between August 2005 and July 2006. Population structure was not significantly different between male and females. Monthly variation of gonadosomatic index (GSI) of both sexes defined spawning period extending from March through July. A similar pattern was also observed in change at maturity stages. For males and females GSI was positively correlated with hepatosomatic index (HSI). Fecundity, ranging from 41,250 to 103,610 eggs, was related to body size, indicating that body size is the useful determinant of fecundity. The sexual maturity ($L_{50}$) was estimated as 14.98 cm TL for males and 19.32 cm TL for females. Parameters of growth estimated by the modified von Bertalanffy growth function model showed that the values of $L_{\infty}$ and K for combined data were 39.12 cm TL and 0.65 $yr^{-1}$. The growth performance index of this study (2.75) was higher than that of the previous study (2.45). This difference could be attributed to sampling method. The recruitment patterns indicated one normally distributed group. Percentage of the recruitment was 51.04% in the spawning season and the highest in August (19.78%).

Performance Evaluation of Nurses in a General Ward Using Data Envelopment Analysis (DEA) (자료포락분석을 활용한 일 병동 간호사의 성과평가 방안)

  • Park, Yeon Hong;Lim, Ji Young
    • Journal of Home Health Care Nursing
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    • v.25 no.1
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    • pp.67-77
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    • 2018
  • Purpose: The purpose of this study was to compare the efficiency of general ward nurses in hospitals using Data Envelopment Analysis (DEA). Methods: Participants were 30 nurses working at a general ward. Input variables were labor cost and time of direct nursing. Output variables were prevention rate of medication error and bedsores, and patient satisfaction. These variables were extracted using literature review and CVI of an expert group. Data were collected from September 18 to October 7, 2017. Data were analyzed using EMS 3.1 program for DEA and descriptive statistics. Results: The average efficiency score of 30 nurses was 0.986, which was very high over all. In the super-efficiency analysis of 11 nurses, their efficiency ranged from 1.0 to 1.047. In addition, when the current output was fixed, the labor cost of nurses did not affect efficiency. Conclusion: This study attempted a new approach concerning performance evaluation of nurses using DEA. This method was useful during appraisal of nurses. We suggest that various input and output variables that were not considered in this study should be added to develop a integrative performance analysis model for nurses.

Developing an Integrated Evaluation Technology for Energy- and Cost-Efficient Building Design Based on BIM in the Real-time Manner

  • Park, Jae Wan;Lee, Yun Gil
    • Architectural research
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    • v.16 no.3
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    • pp.93-100
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    • 2014
  • Existing BIM(Building Information Modeling) based energy evaluation tools cannot be utilized enough for the potential performance of BIM because most of them have not provided the integrated model for energy evaluation, assessment of the material, cost of the construction, and so on. This research aims to propose and develop a new application, EcoBIM, to support an integrated evaluation of the energy and cost efficiencies of the design alternatives within the design process. The proposed application functions as a BIM-based evaluation system that calculates energy-savings performance as well as the construction cost of the alternatives at the design stage. This study mainly focuses on the possibilities of developing the proposed technology. We also suggest an advanced design process using the proposed system, corresponding to changes of national regulations in Korea. This study deduce that EcoBIM can allow architects to make suitable decisions regarding energy- and cost-efficient designs. The proposed design process will allow architects not only to check the eco-friendly performance of design alternatives but also predict the operation cost in a certain period in the future. EcoBIM can prevent large-scale design changes required to obtain environmental certification and enable the owner to make an informed decision about the initial investment of construction according to the result of the analysis of the energy requirement at the design stage.

The effects of circadian disturbances induced by night shifts on the mouse peripheral tissues

  • Seo, Dong-Hyun;Kim, Han-Sung;Ko, Chang-Yong;Schreiber, Jurgen;Jang, Yeong-Su;Bae, Kiho
    • Animal cells and systems
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    • v.16 no.5
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    • pp.357-365
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    • 2012
  • We have examined the effect of circadian disturbances induced by night shifts (NSs) on the phenotypes of the tibiae and abdominal adipose tissues (ADTs) in a mouse model by using in vivo micro-computed tomography (micro-CT). We found that the volumes of total and visceral ADTs in the night-shifted group of mice were significantly larger (69 and 92%, respectively) than those in the control. The mean polar moment of inertia, cross-sectional thickness, and bone mineral density of the cortical bone in the night-shifted group of mice were less (13, 5, and 3%, respectively) than those in the control. Moreover, the volume and the thickness of growth plates (GPs) of the tibiae in the night-shifted mice were significantly smaller (22 and 20%, respectively) than those in the control. Taken together, our results indicate that disturbances in the mouse circadian rhythms induced by NSs affect the morphological characteristics of cortical bone, the volume and the thickness of GPs, and the volume of ADTs.

The Study on the Inter-Organizational Control of IS Outsourcing Relationship : Building Theory from Case Study (정보시스템 아웃소싱 관계에서 조직간 통제에 관한 연구 : 이론구축을 위한 사례연구)

  • Lee, Sang Kon
    • Journal of Information Technology Services
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    • v.3 no.1
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    • pp.127-146
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    • 2004
  • Recently, Information systems (IS) outsourcing has been becoming a viable strategic alternative in the management of information systems. Accordingly, the demand of research in practice has been changed from how to decide IS outsourcing to how to manage IS outsourcing. However, there is little known about the management of IS outsourcing in existing literature. Moreover, the existing studies suggest conflicting solutions in accordance with their own perspectives : competitive relationship vs. cooperative relationship. The purpose of this study is to address this conflicting result, and consequently to enhance an understanding of IS outsourcing management by introducing the concept of interorganizational control. To meet this purpose, this study adopts Lee(2003)'s integrative model of IS outsourcing management based on the existing literature from different management disciplines and different perspectives, and then conducts four case studies. The result reveals that users, as well as IS manager, play a critical role in controlling IS outsourcing. Moreover, they implement a portfolio of control modes including both informal and formal modes. The result also suggests that the choice of particular control mechanism depends on client, supplier, task, and relationship characteristics.

Neural Mechanisms Underlying Antidepressant-Like Effects of Glycyrrhizae Radix in Rats

  • Park, Hyun-Jung;Shim, Hyun-Soo;Shim, In-Sop;Lee, Tae-Hee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.6
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    • pp.1053-1058
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    • 2010
  • Glycyrrhizae radix (GR) is an herbal medicine commonly used in East Asia for treating a variety of diseases, including stomach disorders. In this study, the antidepressant-like activity of GR was investigated using the forced swimming test (FST) in rats. After the FST, the expression of c-Fos and corticotrophin releasing factor (CRF) was assessed by immunochemistry of brain samples from the paraventricular nucleus of the hypothalamus (PVN). The results of the FST showed that a high dose (400 mg/kg) of extract was very effective in reducing immobility(P<0.01), and increased climbing. In addition, treatment with GR (400 mg/kg) significantly decreased the expression of c-Fos and CRF in the PVN, compared to controls. In conclusion, the findings of this study demonstrated that GR effectively reduced behavioral and physiological depression responses in an animal model of depression, suggesting that GR might be useful in the treatment of clinical depression.