• 대한한방부인과학회지
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• 제20권1호
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• pp.268-276
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• 2007

Purpose : The purpose of this study is to report the effect of oriental treatments for Irritable Bowel Syndrome. Methods : We treated a 57 - year - old female who had severe abdominal pain and discomfort companied by alteration in bowel function, a combination of diarrhea and constipation, with Herb medication ( Daechilgitang-gagambang )and acupuncture therapy at the same time. Results : After oriental medical treatment, the clinical symptom of Irritable Bowel Syndrome was improved. Conclusion : This case study shows that the oriental medical therapy is effective in treating irritable bowel syndrome. So that, it is helpful in decreasing the symptoms of patients and in improving quality of life.

• Journal of Acupuncture Research
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• 제18권5호
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• pp.185-194
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• 2001

Objective : By process of treatment for a case which diagnosed as Atlanto-Axial Fracture-Dislocation and admitted from the 2nd, December, 2000 to the 18th, December, 2000, the results are as follows. Methods : Clinical observation and analysis about a case of Atlanto-Axial Fracture-Dislocation was done, who visited Dong-in-dang Oriental Medicine Hospital. This case is managed by integrated therapy of oriental medicine. This patient was diagnosed as stagnation of Ki and stasis of blood(氣滯血瘀), deficiency of Um of the liver and kidneys(肝腎陰虛) and medicated gamisekyung-tang(加味舒經湯) and kanghwalsokdan-tang(羌話續斷湯). As acupucture treatments, we could get the effective results by providing the patient with acupuncture on the nape, shoulder, Lt upper limb and Rt distant point Conclusion : We could get the effective results that case of Atlanto-Axial Fracture-Dislocation with severe rigid neck and Motor disturb of neck, was treated with oriental medicine and acupuncture therapy.

• 국제물리치료학회지
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• 제10권3호
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• pp.1849-1855
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• 2019

Background: Stroke patients require arm movement exercising for various stimulations in standing position for various stimulations rather than in a sitting position because they require integrated skillful movements, such as stretching, holding, and controlling. Objective: This study was conducted to provide foundational clinical data about lower limb global synkinesis in stroke patients using arm movements in a standing position. Design: Randomized controlled trial. Methods: The subjects were divided into a control group (n = 10) and an experimental group (n = 10), and a pre-test was conducted to evaluate leg global synkinesis (GS) and balance. Intervention method is stretching an arm to hold a ball, repeating supination and pronation of the hand only while maintaining the arm extended as much as possible, repeating shoulder abduction and adduction while holding the pegboard. This was followed by a three-week intervention during which re-measurement was conducted in the same way as was done for the pre-test. Results: The control group showed a significant difference in GS and balance during plantar flexion (p<.05), and the experimental group showed a significant difference in GS and balance during all movements (p<.05, p<.01, respectively). There was a significant difference in GS and balance between the two groups during dorsiflexion (p<.05, p<.01, respectively). Conclusion: The findings demonstrate that human arm movements in a standing position can reduce GS in the affected limb, and balance can be improved by stimulating the surrounding tissues of the affected limb and changing them positively.

• 대한물리치료과학회지
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• 제28권3호
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• pp.76-87
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• 2021

Background: The purpose of this study was to evaluate the effects of power walking and square dancing on middle-aged women with hypertension. Design: Randomized controlled Trial. Methods: 30 middle-aged women with hypertension were selected and divided into two groups. 15 cases in the control group received routine treatment, and 15 cases in the intervention group received community vigorous walking and square dancing intervention on the basis of routine treatment. The intervention time was 40-60minutes/day, 5days/week, total 16 weeks. total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL), angiotensin II (Ang II), Leptin, blood pressure, and heart rate were measured. Results: Body weight, body mass index (BMI), TC, TG, LOW-density lipoprotein, angiotensin II, leptin, systolic blood pressure and heart rate were significantly reduced after power walking and square dancing (p<0.05). After the experiment, TC and TG in the experimental group were lower than those in the control group (p<0.05), while HDL was higher (p<0.05). Conclusion: The results of this study suggest that power walking exercises and square dances are significant effects on lipid mechanism and heart rate.

• 한국사회복지학
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• 제66권3호
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• pp.101-131
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• 2014

본 연구는 저소득 우울 여성 독거노인을 대상으로 긍정심리와 해결중심의 기법을 통합한 집단 프로그램을 개발하고, 주관적 안녕감을 구성하는 삶의 만족도, 긍정 정서, 부정 정서, 그리고 우울의 측면에서, 개발된 프로그램의 효과와 효과의 지속성을 검증하는 것을 목적으로 하였다. 이를 위해 기존의 긍정심리 프로그램에 해결중심의 기법을 동화적 방식으로 통합하여 저소득 우울 여성 독거노인에게 적합하도록 개발하였다. 프로그램은 매 90분씩 주 1회로 10주간 10회기 진행되었으며, 효과 검증을 위하여 유사 실험설계의 비동일 비교집단 설계가 사용되었다. 실험집단은 긍정심리 해결중심 통합 집단 프로그램 참여집단이고, 비교집단1은 과거에 노인 우울 감소에 효과가 입증된 집단회상 프로그램 참여집단이며, 개입 없이 기존과 동일하게 재가복지서비스만 받는 집단은 비교집단2로 하였다. 연구 결과 긍정심리 해결중심 통합 집단 프로그램 참여자들의 삶의 만족도와 긍정 정서는 높아졌으며, 부정 정서는 낮아져 주관적 안녕감이 향상되었고 우울은 감소하였다. 또한, 집단회상 프로그램과의 효과 비교에서 프로그램 종료 5주 후와 11주 후에도 변화가 유지되는 것이 확인되어 프로그램의 효과와 효과의 지속성이 검증되었다.

• 대한정형도수물리치료학회지
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• 제12권1호
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• pp.16-26
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• 2006

The purpose of this study was to investigate the influence of the various knee angles and ground state on the muscular activities and fatigue of the ankle muscles by integrated electromyograms (iEMG) and median frequency of tibialis anterior (TA), peroneus longus (PL), flexor digitorum longus (FDL) and gastrocnemius (GC). Ten healthy male subjects were participated into stable and balance ball sessions at four angles of knee joint. The surface electromyograms (sEMG) were recorded from the TA, PL, FDL and GC on stable and balance ball with full weight bearing at four knee angles of $0^{\circ}$, $15^{\circ}$, $30^{\circ}$ and $45^{\circ}$. The time serial data of the surface electromyographic signals were transformed into integrated and frequency serial data by fast fourier transformation. On the stable ground, the iEMG signals of the TA, PL, FDL and GC were significantly higher at $45^{\circ}$ and $30^{\circ}$ of knee angles than $0^{\circ}$ and $15^{\circ}$ of knee flexion (p<0.05). On the balance ball, the iEMG of the TA, PL, FDL and GC were significantly higher at $45^{\circ}$ and $30^{\circ}$ of knee angles than $0^{\circ}$ and $15^{\circ}$ of knee flexion (p<0.05). The median frequency of the TA, PL, FDL and GC were significantly lower at $45^{\circ}$ and $30^{\circ}$ of knee angles than $0^{\circ}$ and $15^{\circ}$ of knee on the stable ground (p<0.05). On the balance ball, also the median frequency of the TA, PL, FDL and GC were significantly lower at $45^{\circ}$ and $30^{\circ}$ of knee angles than $0^{\circ}$ and $15^{\circ}$ of knee flexion (p<0.05). The iEMG of the TA, PL, FDL and GC were significantly higher on the balance ball at $0^{\circ}$, $15^{\circ}$, $30^{\circ}$ and $45^{\circ}$ of knee angles compared with stable ground. The median frequency of the TA, PL, FDL and GC were significantly lower on the balance ball at $0^{\circ}$, $15^{\circ}$, $30^{\circ}$ and $45^{\circ}$ of knee angles compared with stable ground. These results indicate that the ground conditions and angles of the knee joint involved to muscular activities and fatigue of ankles muscles, may performed at first on stable ground and then balance ball in order to $0^{\circ}$, $15^{\circ}$, $30^{\circ}$ and $45^{\circ}$ of knee flexion.

• 생명과학회지
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• 제24권11호
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• pp.1238-1243
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• 2014

중간엽줄기세포(mesenchymal stem cell, MSC)은 세포치료로 각광받아 널리 사용되고 있다. 이들은 줄기세포의 분화성을 이용하여 많은 만성질환에 연관되어 치료제로 사용되고 있다. 줄기세포는 다른 화학적 치료법에 비해 많은 장점을 가지고 있다. 왜냐하면 줄기세포치료는 자기자신, 혹은 동종의 세포를 이용한 치료이기 때문에 화학 치료에 비해 부작용이나 치료의 위험성이 덜하다. 그리고 마이크로RNA또한 최근 기 존재와 기능이 밝혀져서 연구되고 있는데 특히 항암, 세포생장촉진 등의 기능을 이용해 항암, 만성질환 치료에 접목되어 치료제로의 역할이 기대된다. 마이크로RNA는 대부분의 대사과정이나 항상성조절에 관여되어있다. 따라서 마이크로RNA가 저 발현 혹은 과 발현하게 되면 만성질환으로 이어지게 된다. 하지만 줄기세포와 마이크로RNA의 상호간 보조효과는 잘 연구되어 있지 않다. 따라서 이들 간의 상관관계를 확인하기 위하여 태반유래 줄기세포(PDSC)와 골수줄기세포(BM-MSC), 대조군으로 섬유아세포(Fibroblast, WI-38)을 사용하여 이들이 발현하는 마이크로RNA 발현을 확인해 보았다. 각각의 MSC 세포주에 대하여 특정 마이크로RNA의 발현량을 확인해 보았다. 결과 PDSC의 경우엔 마이크로RNA-34a의 발현이 높았고 BM-MSC의 경우에는 마이크로RNA-27a, 33a, 33b, 211의 발현이 높은 것을 확인할 수 있었다. 따라서 우리는 각각의 MSC세포주와 그들이 발현하는 기능성 마이크로RNA을 연관지어 효과적인 세포치료에 활용될 수 있을 것을 기대한다.

• 디지털융복합연구
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• 제15권4호
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• pp.511-519
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• 2017

본 연구는 낮 병동 입원 치매 환자를 대상으로 작업치료 융복합활동프로그램을 실시하여, 치매환자의 손 기능, 인지기능, 수단적일상생활활동에 미치는 영향에 대해 알아보았다. 치매환자 34명을 대상으로 작업치료 융복합활동프로그램과 약물을 동시에 실시한 실험군 17명과 약물치료만 한 17명을 대조군으로 하여 24주간 주 8회 192회기로 실시하였다. 중재 전과 후의 손기능을 알아보기 위해 손의 장악력 검사를 실시하였고, 인지기능을 알아보기 위해 MMSE-K와 GDS를 실시하였다. 또한 수단적일상생활활동을 알아보기 위해 K-IADL를 이용하였다. 중재 결과 실험군에서는 손기능, 인지기능 및 수단적 일상생활활동이 유의하게 증진했지만, 약물치료만 한 대조군에서는 손기능, 인지기능, 수단적 일상생활활동의 증진이 보이지 않았다. 따라서 본 연구 결과 작업치료 융복합활동프로그램은 손기능, 인지기능, 수단적일상생활활동에 긍정적인 영향을 미친다는 것을 알 수 있다.

• Journal of Acupuncture Research
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• 제31권2호
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• pp.173-182
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• 2014

Objectives : There are few reports on treatment of thoracic outlet syndrome in the field of traditional Korean medicine. The aim of this study is to report a case of a 29-year-old male patient diagnosed with thoracic outlet syndrome, whose symptoms were relieved after 3-week integrated Korean medical treatment. Methods : A patient diagnosed with thoracic outlet syndrome was admitted into the Korean medicine hospital. The patient had left shoulder pain and left arm numbness. The pain was worse if it had become cold. The patient was treated using Sa-am acupuncture(Daejangseunggyeok), sweet bee venom acupuncture, herbal medicine and other treatment including physical therapy from September 7th to 27th of 2012. Improvement of the patient's symptoms was evaluated by verbal numerical rating scale(VNRS), skin surface temperature difference between the left and right symmetric part of digital infrared thermographic image(DITI). Results : After 3-weeks of treatment, VNRS decreased and skin surface temperature difference between the left and right symmetric part of DITI showed moderate improvement. Conclusions : The results suggest that integrated Korean medical treatment may affect to reduce the symptoms of thoracic outlet syndrome. Further study is needed to evaluate the importance of this report.

• Current Optics and Photonics
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• 제3권6호
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• pp.555-565
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• 2019

Development of a biomarker for predicting tumor-treatment efficacy is a matter of great concern, to reduce time, medical expense, and effort in oncology therapy. In a preclinical study, we hypothesized that the blood-flow parameter based on laser speckle flowmetry (LSF) could be a potential indicator to estimate the efficacy of breast-cancer treatment. To verify this hypothesis, a 13762-MAT-B-III rat breast tumor was grown in a dorsal skinfold window chamber applied to a nude mouse, and the change in blood flow rate (BFR) - or the speckle flow index (SFI) is used together as the same meaning in this manuscript - was longitudinally monitored during tumor growth and metronomic cyclophosphamide treatment. Based on the daily LSF angiogram, several BFR parameters (baseline SFI, normalized SFI, and △rBFR) were compared to tumor size in the normal, treated, and untreated tumor groups. Despite the incomplete tumor treatment, we found that the daily changes in all BFR parameters tended to have partially positive correlation with tumor size. Moreover, we observed that the changes in baseline SFI and normalized SFI responded one day earlier than the tumor shrinkage during chemotherapy. However, daily variations in the hypercapnia-induced △rBFR lagged tumor shrinkage by one day. This study would contribute not only to evaluating tumor vascular response to treatment, but also to monitoring blood-flow-mediated diseases (in brain, skin, and retina) by using LSF in preclinical settings.