• 한국산학기술학회논문지
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• 제13권10호
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• pp.4462-4470
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• 2012

본 연구는 수 과학의 과정중심 통합 활동이 유아들의 과학적 탐구능력과 태도에 미치는 영향에 대해 알아보고 현장에서의 효율적인 교수학습 및 환경구성을 마련하는데 연구의 목적을 두고 있다. 연구대상은 전라북도 I시에 위치한 W대학 부속 유치원 만3세 만5세 유아 89명을 대상으로 각 연령별 발달을 고려한 주제를 각각 선정하여 수 과학의 과정중심 통합 활동을 실행하였다. 자료 분석은 SPSS for Windows 프로그램을 이용하여 대응표본 t검증을 실시하였고, 결과를 요약하면 다음과 같다. 수 과학의 과정중심 통합 활동을 실시한 결과 과학적 탐구 능력과 과학적 태도를 구성하고 있는 각 하위 요인들이 연령별, 성별로 유의한 차이가 있는 것으로 나타났다. 이러한 결과는 수 과학 과정중심 통합 활동이 만3세 5세 유아들에게 긍정적인 영향을 주는 활동임을 시사하고 있다.

• BMB Reports
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• 제49권2호
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• pp.111-115
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• 2016

Caffeine has been proposed to have several beneficial effects on obesity and its related metabolic diseases; however, how caffeine affects adipocyte differentiation has not been elucidated. In this study, we demonstrated that caffeine suppressed 3T3-L1 adipocyte differentiation and inhibited the expression of CCAAT/enhancer binding protein (C/EBP)α and peroxisome proliferator-activated receptor (PPAR)γ, two main adipogenic transcription factors. Anti-adipogenic markers, such as preadipocyte secreted factor (Pref)-1 and Krüppel-like factor 2, remained to be expressed in the presence of caffeine. Furthermore, 3T3-L1 cells failed to undergo typical mitotic clonal expansion in the presence of caffeine. Investigation of hormonal signaling revealed that caffeine inhibited the activation of AKT and glycogen synthase kinase (GSK) 3 in a dose-dependent manner, but not extracellular signal-regulated kinase (ERK). Our data show that caffeine is an anti-adipogenic bioactive compound involved in the modulation of mitotic clonal expansion during adipocyte differentiation through the AKT/GSK3 pathway.

• Applied Microscopy
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• 제51권
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• pp.7.1-7.9
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• 2021

Neuromorphic systems require integrated structures with high-density memory and selector devices to avoid interference and recognition errors between neighboring memory cells. To improve the performance of a selector device, it is important to understand the characteristics of the switching process. As changes by switching cycle occur at local nanoscale areas, a high-resolution analysis method is needed to investigate this phenomenon. Atomic force microscopy (AFM) is used to analyze the local changes because it offers nanoscale detection with high-resolution capabilities. This review introduces various types of AFM such as conductive AFM (C-AFM), electrostatic force microscopy (EFM), and Kelvin probe force microscopy (KPFM) to study switching behaviors.

• 과학교육연구지
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• 제45권2호
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• pp.143-155
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• 2021

본 연구의 목적은 2018년도부터 적용된 2015개정 교육과정의 통합과학과 과학탐구실험의 지난 3년간의 현장적용 실태를 점검하고, 이를 토대로 2022 개정 교육과정 및 고교학점제에 대비하여 두 과목의 개선 방안을 탐색하려는 것이다. 이를 위해 전국에 분포한 고등학교들이 고르게 포함되도록 지역별로 분배, 표집하여 설문조사를 실시하였으며 총 192개 학교의 과학교사가 설문에 참여하였다. 또한 과학과 선택과목 재구조화에 대한 현장전문가의 의견을 조사하기 위해 12명의 고등학교 과학 교사들을 초점집단으로 선정하여 심층면담을 실시하였다. 주요 연구결과를 살펴보면, 설문조사에서 통합과학의 경우 현장적용 3년차를 맞이하여 대부분의 학교에서 6~8단위로 편성·운영하는 것으로 나타났으며, 학급당 통합과학 담당 교사는 3개년도 평균 2~3명으로 나타났다. 과학탐구실험의 경우 학기당 1단위씩 총2개 학기로 편성·운영하는 경우가 가장 많았으며, 부족한 시수를 채우기 위해 여러 명의 과학교사가 과학탐구실험을 담당하고 있는 것으로 나타났다. 심층면담에서 과학교사들은 향후 고교학점제에 대비하여 학기단위 집중이수가 가능한 규모로 통합과학을 축소하고, 핵심역량을 강화하여 재구조화해야 한다고 주장하였다. 연구결과를 토대로 2022개정 교육과정의 고등학교 공통과목 재구조화에 주는 시사점을 학기단위 집중이수가 가능하도록 통합과학을 빅아이디어를 중심으로 재구성하는 방안, 선택과목 수강을 안내할 수 있는 기본 과학개념을 중심으로 과학과 공통과목을 구성하는 방안, 고등학교 1학년 과학과 공통과목을 통한 선택과목 안내 및 진로지도의 필요성, 과학영역간 간학문적, 다학문적 통합·융합 과목을 지도를 위한 교사 전문성 강화의 필요성 등을 제안하였다.

• 한국과학교육학회지
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• 제33권1호
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• pp.208-227
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• 2013

본 연구에서는 중등 과학교사의 통합과학수업을 설계하는 과정에서 나타나는 특징을 심층적으로 사례분석하였다. 이를 위하여 통합과학교육과 관련된 선행 연구와 문헌을 분석하여 이 연구에서 적용할 통합과학이론을 정립한 후, 이를 실제 수업을 설계할 교사(중학교 교사1인, 고등학교 교사 1인)와 공유하였다. 그리고 선행연구에서 적용하였던 '통합과학 5단계 수업 계획서' 양식을 연구진과 교사가 공유하고, 이를 적용하여 교사가 통합과학수업 계획서를 설계하도록 하였다. 통합과학수업을 위한 단원 선정, 교육과정 분석, 구체적인 수업 계획서 설계(8차시분) 등의 모든 과정은 연구진의 컨설팅 내용을 바탕으로 교사가 주도적으로 개발하도록 하였다. 모든 컨설팅 과정은 연구진의 관찰일지로 정리하였으며 협의 과정에서 면담지를 작성하였고, 이를 통하여 수업교사의 수업설계 과정에서의 어려움과 특징을 심층적으로 분석하였다. 연구결과, 중학교 교사와 고등학교 교사는 모두 통합과학수업을 준비하는 데 있어서 많은 어려움을 겪은 것으로 나타났다. 특히 통합과학수업을 위한 전체적인 통합의 방향과 수업주제를 설정하여, 이와 관련된 내용을 선정하고, 수업 내용을 재구성 및 조직화하는 단계에서 가장 어려움을 크게 느낀 것으로 분석되었다.

• Journal of Forest and Environmental Science
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• 제38권2호
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• pp.75-89
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• 2022

The negative impact of monoculture rubber plantations on biodiversity and associated ecological processes/ecosystem services has led to suggestions on the use of integrated land use systems for rubber cultivation and production in order to ensure environmental sustainability. However, there is paucity of information on the effect of such integrated land use systems on the diversity and abundance of the rubber plantation undergrowth. We evaluated and compared undergrowth plant species composition, richness, abundance, diversity and interaction, in three integrated systems (Rubber-Strelitzia reginae Integrated System - RSrIS, Rubber-Podocarpus nagi Integrated System - RPnIS & Naturally Managed Rubber Plantation - NMRP) with three Rubber Monoculture Plantations (RMP₁, RMP₂ & RMP₃) adjacent to the integrated systems, respectively, at the Investigation and Experiment Station of Tropical Crops, Danzhou, Hainan, China. Undergrowth species density was higher in the rubber monocultures than in the integrated systems except in RSrIS. Species richness and diversity were also higher in the monocultures except in NMRP. Species similarity/interaction between the monocultures and the integrated systems was highest between RMP₃ and NMRP. The NRMP proved to be the best model of natural rubber integrated system for the conservation of undergrowth species richness, diversity and interspecific interaction. However, the conservation of undergrowth species in other forms of integrated natural systems can be enhanced by considering the ecology of species to be integrated in terms of their growth characteristics, competitive nature, and ability to grow in association with other species.

• 치위생과학회지
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• 제22권2호
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• pp.115-125
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• 2022

Background: In the dental hygiene curriculum, efforts are being made to introduce an integrated curriculum based on the competency of a dental hygienist. Because there is a connection and overlap in learning contents between Dental Nutrition and Oral Biochemistry, which are basic dental hygiene subjects, it is possible to integrate these two subjects. This study aims to derive Nutritional Biochemistry as an integrated curriculum for Dental Nutrition and Oral Biochemistry, and to develop learning goals and competencies for Dental Nutritional Biochemistry. Methods: The learning contents of the integrated curriculum were composed by referring to the contents of the Dental Nutrition and Oral Biochemistry textbooks, and learning goals were derived from the learning contents. Moreover, competency was developed by analyzing the duties of a dental hygienist that can be performed through the learning goals. The Delphi survey was conducted twice to verify the content validity ratio (CVR) of the competence and the learning goal of the integrated curriculum. Results: In the first Delphi survey, the CVR for two competencies was 0.56 or higher. Moreover, it was revised based on expert's opinions, and as a result of the second Delphi survey after the revision, the CVR was either increased or maintained. Eighty-five learning goals were derived by referring to the textbook. According to CVR and expert opinions, after the first Delphi survey, the number of learning goals was reduced to 69. After the second Delphi survey, 68 learning goals were finally derived. Conclusion: The development process of the integrated curriculum conducted in this study can be utilized for integration between subjects in basic dental hygiene.

• 아동학회지
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• 제31권6호
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• pp.51-69
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• 2010

This research involved the conducting of an experiment in order to determine the relative effectiveness of constructivist science education when integrated with art experience and constructivist science education for young children. Forty-one children of five years of age in two daycare center classes were assigned to experimental and comparative groups. The experimental and comparative group participated in 15 units. The experimental group participated in science education integrated with art experience, while the comparative group participated in science education. The analysis of covariance revealed significant differences between the mean scores of the two groups on the posttests for science process skills and attitudes. This indicates that the children in the experimental group performed significantly better on the tests than the children in the comparative group. The results of this study suggest that incorporating constructivist science education activities with art experience are good activities for developing young children's science process skills and attitudes.

• 한국지구과학회지
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• 제40권4호
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• pp.436-445
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• 2019

This study presents how two types of integrated science and engineering lessons affect students' engineering problem solving skills and their perceptions of engineering. In total, 146 middle school students participated in this study. Eighty-six students participated in the Type I lesson (complete engineering design lesson with a science knowledge application) and 60 students participated in the Type II lesson (engineering design without a science knowledge application). Two main datasets, (1) students' Creative Engineering Problem Solving Propensity (CEPSP) measurement scores and (2) open-ended survey questions about students' perceptions of engineering, were collected before and after the lessons. The results of this study show that after participating in the Type I lesson, students' CEPSP scores significantly increased, whereas the CEPSP scores of the students who participated in the Type II lesson did not increase significantly. In addition, students who participated in the Type I lesson perceived engineering and the engineering integrated science lesson differently compared to the students who participated in the Type II lesson. The results of this study show that engineering integrated science, technology, engineering & mathematics (STEM) lessons should include a complete engineering design and a science knowledge application to improve students' engineering problem solving skills.

• Journal of Microbiology and Biotechnology
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• 제21권12호
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• pp.1228-1235
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• 2011

We compared the gene expression among four clinical and five environmental V. vulnificus isolates, using a cDNA microarray containing 131 genes possibly associated with pathogenicity, transport, signal transduction, and gene regulations in the pathogen. cDNAs from total RNAs of these isolates were hybridized into the cDNA microarray using the cDNA of the wild-type strain MO6-24/O as a reference. We focused on selecting differentially expressed (DE) genes between clinical and environmental isolates using a modified t-statistic. We could detect two statistically significant DE genes between virulent isolates and less-virulent isolates with a marginal statistical significance (p-value of 0.008). These were genes putatively encoding pilin and adenlyate cylase. Real time-PCR confirmed that these two selected genes transcribed in significantly higher levels in virulent isolates than in less-virulent isolates. Mutants with lesions in the gene encoding pilin showed significantly higher $LD_{50}$ values than that of wild type.