• Title/Summary/Keyword: Integrated assembly

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Analysis of the Genome Sequence of Strain GiC-126 of Gloeostereum incarnatum with Genetic Linkage Map

  • Jiang, Wan-Zhu;Yao, Fang-Jie;Fang, Ming;Lu, Li-Xin;Zhang, You-Min;Wang, Peng;Meng, Jing-Jing;Lu, Jia;Ma, Xiao-Xu;He, Qi;Shao, Kai-Sheng;Khan, Asif Ali;Wei, Yun-Hui
    • Mycobiology
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    • v.49 no.4
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    • pp.406-420
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    • 2021
  • Gloeostereum incarnatum has edible and medicinal value and was first cultivated and domesticated in China. We sequenced the G. incarnatum monokaryotic strain GiC-126 on an Illumina HiSeq X Ten system and obtained a 34.52-Mb genome assembly sequence that encoded 16,895 predicted genes. We combined the GiC-126 genome with the published genome of G. incarnatum strain CCMJ2665 to construct a genetic linkage map (GiC-126 genome) that had 10 linkage groups (LGs), and the 15 assembly sequences of CCMJ2665 were integrated into 8 LGs. We identified 1912 simple sequence repeat (SSR) loci and detected 700 genes containing 768 SSRs in the genome; 65 and 100 of them were annotated with gene ontology (GO) terms and KEGG pathways, respectively. Carbohydrate-active enzymes (CAZymes) were identified in 20 fungal genomes and annotated; among them, 144 CAZymes were annotated in the GiC-126 genome. The A mating-type locus (MAT-A) of G. incarnatum was located on scaffold885 at 38.9 cM of LG1 and was flanked by two homeodomain (HD1) genes, mip and beta-fg. Fourteen segregation distortion markers were detected in the genetic linkage map, all of which were skewed toward the parent GiC-126. They formed three segregation distortion regions (SDR1-SDR3), and 22 predictive genes were found in scaffold1920 where three segregation distortion markers were located in SDR1. In this study, we corrected and updated the genomic information of G. incarnatum. Our results will provide a theoretical basis for fine gene mapping, functional gene cloning, and genetic breeding the follow-up of G. incarnatum.

Development of Automated 3D Modeling System to Construct BIM for Railway Bridge (철도 교량의 BIM 구축을 위한 3차원 모델 생성 자동화 시스템 개발)

  • Lee, Heon-Min;Kim, Hyun-Seung;Lee, Il-Soo
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.31 no.5
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    • pp.267-274
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    • 2018
  • For successful BIM settlement, it is a key technic for engineer to design structures in the 3-dimensional digital space and to work out related design documents directly. Lately many BIM tool has been released and each supports their 3-dimensional object libraries. But it is not easy to apply those libraries to design transportation infra structures that were placed along the route(3-dimensional line). Moreover, in case of design changes, it is so difficult to reflect those changes with the integrated model that was assembled by them. Because of they were developed without consideration for redundancy of parameters between objects that were placed nearby or were related each other. In this paper, a method to develop module for modeling and placing 3-dimensional object for transportation infra structures is presented. The modules are employed by a parametric method and can deal with design changes. Also, for a railroad bridge, through developing user interface of the integrated 3-dimensional model that was assembled by those modules the applicability of them was reviewed.

Mechanical Bending Process and Application for a Large Curved Shell Plate by Multiple Point Press Machine (무금형 다점 펀치를 사용한 선체외판의 분할 성형 가공 정보 계산 시스템 개발)

  • Hwang, Se-Yun;Lee, Jang-Hyun;Ryu, Cheol-Ho;Han, Myung-Soo;Kim, Kwang-Ho;Kim, Kwang-Sik
    • Journal of the Society of Naval Architects of Korea
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    • v.48 no.6
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    • pp.528-538
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    • 2011
  • As a forming method for curved hull plates more efficient than the flame bending, mechanical bending using multi point press forming and die-less forming is discussed in this paper. the mechanical forming is a flexible manufacturing system for automatically forming of hull parts. It is especially suited to varied curved parts. This paper discusses a multiple point pressing machine composed of a pair of reconfigurable punches in order to achieve the rapid forming of curved hull plates using division forming and presents how forming information is obtained from the given design surface. Although the mechanical forming can be efficient in the metal forming, spring back after pressing is a phenomenon which must be carefully considered when quantifying the process variables. If the spring back is not accurately controlled, the fabricated shell plate cannot meet assembly tolerance. This paper describes the principles to calculate the proper stroke of each punch at the divided areas. the strokes are determined by an iterative process of sequential pressing and spring back compensation from an unfolded flat shape to its given design surface. FEA(finite element analysis) is used to simulate the spring back of the plate and the IDA(iterative displacement adjustment) method adjusts the offset of pressing punches from the deformation results and the design surface. The shape deviations of two surfaces due to spring back are compensated by integrated system using FEA and IDA method. For the practical application, It is aimed to develop an integrated system that can automatically perform the compensation process and calculate strokes of punches of the double sides' reconfigurable multiple-press machine and some experimental results obtained with mechanical bending are presented.

A Study on the Integrated Management System of Municipal Solid Waste from Seoul Metropolitan City (서울시 일반폐기물의 통합적 관리체계에 관한 연구)

  • 우세홍;홍상균
    • Journal of Environmental Health Sciences
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    • v.19 no.4
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    • pp.51-58
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    • 1993
  • The integrated solid waste management for Seoul Metropolitan city can be established on the basis of the following hierarchy of priorities: 1. Efforts for source reduction should be propelled by both government and citizens to achieve the effects of resource conservation. The adequate production and consumption which are environmentally amenable and sustainable can be induced by the reasonable imposition of deposit money for waste treatment to one-time use products. To accomplish source reduction effectively, the induction of legal and institutional regulation of producer and consumer participation is requisite. 2. For resource recovery, wastes generated should be recycled as far as practicable. Community residents are responsible to separate discharge, the authorities concerned have responsibility of separate collection, and recycling industry should be assissted through tax reduction and financing. Resource separation facilities can be constructed at Kimpo Metropolitan landfill site for wastes not separately collected due to some unavoidable circumstances. 3. Garbage should be composted. Garbage is uneconomical for incineration, because it has high moisture content and low calorie, thus there is no reason for the incineration of garbage even though garbage is classified into combustibles. Composting facilities can be located at sites which are not densely populated and easily accessible to transportation, for example, Kimpo Metropolitan landfill site. Compost produced can be managed by the authorities for the use of fertilizer to a green tract of suburban land and farms. 4. Nonhazardous combustible wastes not recyclable can be utilized for thermal recovery at the incinerators which are completely equipped with pollution control devices. According to the trend of local autonomy and the equity principle of local autonomous entities, incineration facilities of minimal capacity required can be constructed at each districts of Seoul Metropolitan city which have organized local assembly. In case of Yangcheon district, the economically combustible waste quantity is about 260 tons/day which exceeds 150 tons/day, the incineration capacity of existing facility. But, from now on, waste quantity can be reduced substantially by the intensive efforts of citizens for source reduction and recycling and the institutional support of administrative organizations. Especially, it is indispensable for the government to constitute institutional and technological bases that can recycle paper and plastics form 43% of waste generated. A good time for constructing of incineration facilities for municipal solid waste can be postponed to the time that pollution control technologies of domestic enterprises are fully developed to satisfy the standards of air pollution prevention, because the life expectancy of Kimpo Metropolitan landfill site is about 25 years. Within this period, institutional improvements and technological advancements can be attained, while the air qual. ity of Seoul Metropolitan city can be ameliorated to the level to afford incineration facilities. 5. For final disposal, incombustibles and ash are landfilled sanitarily at Kimpo Metropolitan landfill site.

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A Study on System Construction to the Product Liability Law-with focus on a small & medium business (제조물책임법에 대응하기 위한 시스템 구축에 관한 연구 -중소기업을 중심으로-)

  • Han, Min-Suk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.6
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    • pp.596-608
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    • 2017
  • In 2002, the government arranged an institutional strategy to make it possible for a consumers to make a claim for damages caused by product defects against a business that produces and sells a product by enforcing the Product Liability Law(hereinafter referred to as 'PL'). On the other hand, due to the recent humidifier sterilizer accident, approximately 12 cases of related bills, such as a revised bill for the product liability law, have been proposed to the National Assembly at present in an effort to introduce the group action system and punitive compensation system for the purpose of the strengthening of the corporate product liability, and consumer damage relief. Ironically, as much as 62.6% of small & medium businesses, which are actual interested parties to this bill, are unaware of this. Many companies are responding to PL with the rationalization of document preparation & storage, clarification of responsibility relations with related business operators, and PL insurance policy purchase, or securing compensation funds as a means of Product Liability Defense(PLD), but the methods of preparation such as this leave much room for limits on the considerations of product design and product safety. This paper presents the individual management system model with more focus on product safety by looking into the clear concept of PL and the countermeasures against it, grasping the relevance between the PL system and individual management system, and integrating the PL response system in preparation for the PL. It is hoped that the result of this research objective will be evaluated as a rational countermeasure for small & medium businesses to respond effectively to the PL.

A Study on Typological Approach for Interior Design Planning (실내계획이론으로서의 유형학적 접근에 관한 연구)

  • 한경희;이선민
    • Korean Institute of Interior Design Journal
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    • no.16
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    • pp.153-160
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    • 1998
  • The past and present time are consistent thinking process system which composed of single concept not separated concept. It's common concept for interior designer to how to realize the thinking process system in actual present day. So this paper was focused on purpose of establishing for procedural process theory by approaching typological process system in interior design process. Interior design being composed of typological thinking process system has been headed as a critical issue to how to transplant well between the design and typological objects. Also we have to be needed to know for the process of visual expression and verbal ability to be able to extract the designer's elements from it. Through the process of visual expression and verbal ability to be able to extract the designer's elements from it. Through the process of visual transformation and analysis we have to extract concepts with united design objects. From these process it should be followed adequate adjudgment on the extracted fragments' assembly and dissociation methods through physical limitation of elements functionality and feasibility's measurements. Therefore from the morphological designed results reflected to typological concepts finished material detail and texture we should be able to take the integrated thinking process system. Lastly interior designer should be able to check whether it was best choice from the consistent design feedback process to ask whether it contains the conceptual design process and new typological objects without non-conformity between past and present days in interior space. Now we should be asked for development of practical design process to be able to realize above assumptions called "Development and Suceeding of Cultural Value System'. Additionally, we have to continue to develop for our true meaning of interior design process, not repetition of past's imitation.tion.

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Effect of Climate Change and Urbanization on Flow and BOD Concentration Duration Curves (기후변화 및 도시화에 따른 유황곡선 및 BOD 농도지속곡선 변화)

  • Park, Kyung-Shin;Chung, Eun-Sung;Kim, Sang-Ug;Lee, Kil-Seong
    • Journal of Korea Water Resources Association
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    • v.42 no.12
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    • pp.1091-1102
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    • 2009
  • This study developed an integrated approach to climate change and urbanization impact assessment by linking models of SDSM (statistical downscaling model), HSPF (hydrological simulation program?Fortran) and ICM (impervious cover model). A case study of the Anyangcheon watershed illustrated how the proposed framework can be used to analyze the impacts of climate change and urbanization in terms of flood control, water security and water quality. The evaluation criteria were the variations of flow and pollutant concentration duration curves. In this study, nine scenarios including three climate (present condition, A1B and A2) and three urbanization scenarios were analyzed using HSPF model. As a result, climate change is a large influence on the flowrate and the urbanization affects the pollutant concentration. Therefore, the impacts of both climate change and urbanization must be included into the watershed management and water resources planning for sustainable development.

Design of a Coordinating Mechanism for Multi-Level Scheduling Systems in Supply Chain

  • Lee, Jung-Seung;Kim, Soo
    • Journal of Information Technology Applications and Management
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    • v.19 no.1
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    • pp.37-46
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    • 2012
  • The scheduling problem of large products like ships, airplanes, space shuttles, assembled constructions, and automobiles is very complex in nature. To reduce inherent computational complexity, we often design scheduling systems that the original problem is decomposed into small sub-problems, which are scheduled independently and integrated into the original one. Moreover, the steep growth of communication technology and logistics makes it possible to produce a lot of multi-nation corporation by which products are produced across more than one plant. Therefore vertical and lateral coordination among decomposed scheduling systems is necessary. In this research, we suggest an agent-based coordinating mechanism for multi-level scheduling systems in supply chain. For design of a general coordination mechanism, at first, we propose a grammar to define individual scheduling agents which are responsible to their own plants, and a meta-level coordination agent which is engaged to supervise individual scheduling agents. Second, we suggest scheduling agent communication protocols for each scheduling agent topology which is classified according to the system architecture, existence of coordinator, and direction of coordination. We also suggest a scheduling agent communication language which consists of three layers : Agent Communication Layer, Scheduling Coordination Layer, Industry-specific Layer. Finally, in order to improve the efficiency of communication among scheduling agents we suggest a rough capacity coordination model which supports to monitor participating agents and analyze the status of them. With this coordination mechanism, we can easily model coordination processes of multiple scheduling systems. In the future, we will apply this mechanism to shipbuilding domain and develop a prototype system which consists of a dock-scheduling agent, four assembly-plant-scheduling agents, and a meta-level coordination agent. A series of experiment using the real-world data will be performed to examine this mechanism.

Cognitive Development Evaluation of Haptic Puzzle Game Using a Haptic Pen (촉각펜을 이용한 햅틱 퍼즐게임의 인지 발달 평가)

  • Chung, Dong-Hun
    • Journal of Korea Game Society
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    • v.9 no.4
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    • pp.45-56
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    • 2009
  • It is necessary for young children to integrate the sense of sight, hearing, touch, etc. for developing their emotion and cognition. Thanks to Information and Communication Technology (ICT) development, young children have more opportunities to use various senses in learning process. However, ICT learning method is more focusing on the sense of sight and hearing, and lacks of integrated recognition and this fact leads to the reason why ICT can not be used as a main education tool. Therefore, this study evaluated the influence of wUbi-Pen(haptic device) on cognition using a computer puzzle program. The results show that young children using a haptic pen have greater intention and performance in object assembly, mazes, picture completion in K-WPPSI test than those of non-using haptic pen. This implies that haptic function should be considered in ICT material and indeed useful in various cognition-related symptoms and diseases.

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A Low Insertion Loss CBFGCPW-Microstrip Transition and Its Application to MIC Module Integration (저 손실을 갖는 CBFGCPW-Microstrip 천이 구조의 해석 및 MIC 모듈 집적화에 응용)

  • Lim, Ju-Hyun;Yang, Seong-Sik;Yeom, Kyung-Whan
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.18 no.7
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    • pp.809-818
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    • 2007
  • Generally, carriers on which microwave circuits are mounted are used as building blocks of MIC module for the convenience of MIC assembly and the unit module characterization. However the interconnection of the microstrip-based carriers by wire bonding causes the serious problem of mismatch and results in the higher insertion loss as frequency becomes higher. The gap and the depth between carriers are considered as the main reason of the degradation. The CPW can be the solution to cope with such problem considering its field are dominantly concentrated on the top plane. In this paper, we propose and demonstrate the CBFGCPW to microstrip transition with the low insertion loss that can be applied without causing the MIC carrier interconnection problem.