• Geophysics and Geophysical Exploration
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• v.11 no.2
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• pp.109-115
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• 2008

It is very important to estimate the physical properties of survey area and delineate the geological basement in marine site survey for the design of offshore structures. For the purpose of providing high quality data by means of engineering site survey, it is necessary to apply several survey techniques and carry out the integrated interpretation to each other. In this study, we applied single channel seismic reflection method and OBC (Ocean Bottom Cable) type seismic refraction method at shallow marine. We used a dual boomer-single channel streamer as a source-receiver in seismic reflection survey and airgun source-the developed OBC type streamer in seismic refraction survey. We made 24 channels OBC type streamer which has 4m channel interval and each channel is composed of single hydrophone and preamplifier. We tested the field applicability of the proposed method and applied the typical seismic data processing methods to the obtained reflection data in order to enhance the data quality and image resolution. In order to estimate the geological velocity distribution from refraction data, seismic refraction tomography technique was applied. Therefore, we could successfully perform time-depth conversion using the velocity information as an integrated interpretation. The proposed method could provide reliable geologic information such as sediment layer thickness and 3D basement depth map.

• Journal of Biomedical Engineering Research
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• v.15 no.3
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• pp.317-324
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• 1994

This paper proposed a new method in the implementation of ISDN (integrated services digital network) LAPD (link access procedure on the D-channel) and LAPB (link access procedure on the B-channel) protocols. The proposed method in this paper implement ISDW LAPD protocol through multi-tasking operating system and adopt a kernel part that is changed operating system to target board. The features of implemented system are (1) the para.llel processing of the events generated at each layer, as follows (2) the supporting necessary timers for the implementation of ISDW LAPD protocol from the kernel part by using software, (3) the recommanded SAP (Service Access Point) from CCITT was composed by using port function in the operating system. With the proposed method, the protocols of ISDH layerl, layer2 and layer3 (call control) were implemented by using the kernel part and related tests were carried out by connecting the ISDH terminal simulator to ISDN S-interface system using the ISDN LAPD protocol The results showed that ISDW S-interface terminals could be discriminated by TEI (Terminal Equipment Identifier) assignment in layer 2 (LAPD) and the message transmission of layer 3 was verified by establishing the multi-frame transmission and then through the path established by the LAPD protocol, a user data was tranfered and received on B-channel with LAPB protocol Thererfore, as new efficient ISDN S-interface environment was implemented in the thesis, it was verified that the implemented system can be utilized by connecting ISDW in the future to transfer a medical image data.

• Cartoon and Animation Studies
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• s.49
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• pp.425-464
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• 2017

The Knowledge of the Channel (e) is often used as educational materials; it delivers very short but compelling message of strong or interesting timeliness. However, as the media environment changes, expectations and demands for The Knowledge The Knowledge of the Channel (e) is used in school education and what should be improved upon to increase utilization of educational resources. We surveyed 361 elementary, middle and high school teachers and analyzed the frequency of using, approach and learning activities of The Knowledge of the Channel (e) in school education. We also analyzed difficulties in using it in the school and what improvements should be made. Result show that the frequency of using The Knowledge of the Channel (e) in school is highest in elementary schools, followed by middle school, and then high school. Teachers strongly consider curricular relevance when selecting broadcasting contents for education, and among programs of EBS(Educational Broadcasting System), most frequently use The Knowledge of the Channel (e). The The Knowledge of the Channel (e) is mainly used as an incentive for increasing motivation. When examined by elementary school curriculum, this material is highly utilized in subjects with content such as society, morality, and science, or with approaches that require various perspectives. However, it is difficult for teachers to find materials directly related to their classes, and since other media content similar to The Knowledge of the Channel (e) is abundant, the utilization of The Knowledge of the Channel (e) is decreasing. To improve this, The Knowledge of the Channel (e) needs to improve its platform and transformed the type of The Knowledge of the Channel (e) content being provided on social media.

• Biomolecules & Therapeutics
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• v.30 no.5
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• pp.455-464
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• 2022

Efonidipine, a calcium channel blocker, is widely used for the treatment of hypertension and cardiovascular diseases. In our preliminary study using structure-based virtual screening, efonidipine was identified as a potential inhibitor of c-Jun N-terminal kinase 3 (JNK3). Although its antihypertensive effect is widely known, the role of efonidipine in the central nervous system has remained elusive. The present study investigated the effects of efonidipine on the inflammation and cell migration induced by lipopolysaccharide (LPS) using murine BV2 and human HMC3 microglial cell lines and elucidated signaling molecules mediating its effects. We found that the phosphorylations of JNK and its downstream molecule c-Jun in LPS-treated BV2 cells were declined by efonidipine, confirming the finding from virtual screening. In addition, efonidipine inhibited the LPS-induced production of pro-inflammatory factors, including interleukin-1β (IL-1β) and nitric oxide. Similarly, the IL-1β production in LPS-treated HMC3 cells was also inhibited by efonidipine. Efonidipine markedly impeded cell migration stimulated by LPS in both cells. Furthermore, it inhibited the phosphorylation of inhibitor kappa B, thereby suppressing nuclear translocation of nuclear factor-κB (NF-κB) in LPS-treated BV2 cells. Taken together, efonidipine exerts anti-inflammatory and anti-migratory effects in LPS-treated microglial cells through inhibition of the JNK/NF-κB pathway. These findings imply that efonidipine may be a potential candidate for drug repositioning, with beneficial impacts on brain disorders associated with neuroinflammation.

• Asia pacific journal of information systems
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• v.17 no.2
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• pp.83-95
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• 2007

We are motivated by how offline and online firms compete. The Internet made many conventional offline firms build a dynamic online business as another sales channel using their advantages such as brand equity, an existing customer base with comprehensive purchasing data, integrated marketing, economies of scale, and longtime experience with the logistics of order fulfillment and customer service. Even though the hybrid selling using both offline and online channel seems to have advantages over a pure online retailer, all the conventional offline firms are not seen to create an online business. Many conventional offline firms began to launch online business since the Internet era, however, just being online business is not likely to guarantee success. According to Bizate.com's report whether the hybrid channel strategy is successful is still under investigation. For example, consider the classic case of Barnes and Noble versus Amazon.com, Barnes and Noble was already the largest chain of bookstores in the U,S., when Amazon.com was established in 1995, BarnesandNoble.com followed suit in 1997, After suffering losses in its initial years, Amazon finally turned profitable in 2003. In 2004, Amazon's net income was $588 million on revenues of $6.92 billion, while Barnes and Noble earned $143 million on revenues of $4.87 billion, which included BarnesandNoble.com's loss of $21 million on revenues of $420 million. While these examples serve to motivate our thinking, it does not explain when offline firms should venture online. It also does not provide an analytical framework that can generalized to other competitive online-offline situations. We attempt to do this in this paper and analyze a hybrid channel model where a conventional offline firm competes against online firms using its own direct online channels. We are particularly interested in an optimal channel strategy when a conventional offline firm sells its products through its own direct online channel to compete with other rival online firms. We consider two situations where its direct online channel and other online firms are symmetric and asymmetric in the brand effect. The analysis of this paper presents several findings. In the symmetric model where a hybrid firm's online channel is not differentiated from a pure online firm, (i) a conventional offline firm will not launch its online business. In the asymmetric model where a hybrid firm's online channel is differentiated from a pure online firm, (ii) a conventional offline firm can launch its online business if its brand effect is greater than a certain threshold. (iii) there is a positive relationship between its brand effect and online customer costs showing that a conventional offline firm needs more brand effect in order to launch online business as online customer costs decrease. (iv) there is a negative relationship between its brand effect and the number of customers with access to the Internet showing that a conventional offline firm tends to launch its online business when customers with access to the Internet increases.

• Journal of computational fluids engineering
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• v.16 no.2
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• pp.49-55
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• 2011

Turbulent flows with wavy wall are simulated using Residual-based Variational Multiscale Method (RB-VMS) which is proposed by Bazilves et al(2007) as new Large Eddy Simulation methodology. Incompressible Navier-Stokes equations are integrated using Isogeometric analysis which adopt the basis function as NURBS. The Reynolds number is 6760 based on the bulk velocity and averaged channel height. And the amplitude (${\alpha}/{\lambda}$) of wavy wall is 0.05. The computational domain is $2{\lambda}{\times}1.05{\lambda}{\times}{\lambda}$ in the streamwise, wall normal and spanwise direction. Mean quantities and turbulent statistics near wavy wall are compared with DNS results of Cherukat et al.(1998). The predicted results show good agreement with reference data.

• ETRI Journal
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• v.21 no.3
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• pp.22-28
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• 1999

A new tapered TEOS oxide technique has been developed to use field oxide of the power integrated circuits. It provides better uniformity of less than 3 % and reproducibility. On-resistance of P-channel RESURE (REduced SURface Field) LDMOS transistors has been optimized and improved by using a novel simulation and tapered TEOS field oxide on the drift region of the devices. With the similar breakdown voltage, at $V_{gs}$=-0.5V, the specific on-resistance of the LDMOS with the tapered field oxide is about $31.5{\Omega}{\cdot}cm^2$, while that of the LDMOS with the conventional field oxide is about $57m{\Omega}{\cdot}cm^2$.

• Proceedings of the KIEE Conference
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• 2004.11c
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• pp.417-419
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• 2004

Because of the demands for high performance and high integrated system, the needs for optimal platform becomes more importance. Optimal platform can handle more data effectively with same resources. AMBA(Advanced Microprocessor Bus Architecture)$^{TM}$ defines on-chip communication standard for designing high performance embedded micro-controllers. It is consisted of AHB, ASB and APB. It can support fast implementation and reliability in system that is composed with reusable IPs. DMAC is one of master in system and generate master signals of AHB to communicate data from one slave(peripheral or memory) to another slave. It can reduce burden of CPU and increase system performance. We designed DMAC based on AMBA and it supports 13 Channels. Each channel can be controlled by software program. It decides channel's priority using round-robin method. It can support P2P, P2M, M2P and P2P communication.

• Journal of Mechanical Science and Technology
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• v.14 no.9
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• pp.997-1004
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• 2000

The experiments were conducted by using water and paraffin slurry to investigate the effect of a chip spacing in the multichip module on the cooling characteristics from an in-line $4{\times}3$ array of discrete heat sources which were flush mounted on the top wall of a channel. The experimental parameters were chip spacing in a multichip module, heat flux of simulated VLSI chip, mass fraction of paraffin slurry, and channel Reynolds number. The removable heat flux at the same chip surface temperature decreased as the chip spacing decreased at the first and fourth rows. The local heat transfer coefficients for the paraffin slurry were larger than those for water, and the chip spacing on the local heat transfer coefficients for paraffin slurry influenced less than that for water. The enhancement factor for paraffin slurry showed the largest value at a mass fraction of 5% regardless of the chip spacing, and the enhancement factors increased as the chip spacing decreased. This means that the paraffin slurry is more effective than water for cooling of the highly integrated multichip module.

• Journal of Sensor Science and Technology
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• v.26 no.2
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• pp.79-84
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• 2017

The drain current of the SB MOSFET was analytically modeled by an equation composed of thermionic emission and tunneling with consideration of the image force lowering. The depletion region electron concentration was used to model the channel electron concentration for the tunneling current. The Schottky barrier width is dependent on the channel electron concentration. The drain current is changed by the gate oxide thickness and Schottky barrier height, but it is hardly changed by the doping concentration. For a GaN SB MOSFET with ITO source and drain electrodes, the calculated threshold voltage was 3.5 V which was similar to the measured value of 3.75 V and the calculated drain current was 1.2 times higher than the measured.