• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.1151-1154
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• 2013

Background: Changes in dietary practices are known to be associated with changes in the health and disease pattern of a population. This study aimed to qualitatively explore the perception of colorectal cancer patients regarding causes of colorectal cancer and the influence of diet. Materials and Methods: Twelve respondents from three major ethnicities in Malaysia were selected from the quantitative study on dietary pattern and colorectal cancer carried out earlier in this study. In-depth interviews (IDI), conducted from April until June 2012, were mainly in the Malay language with additional use of English and continued until the saturation point was reached. All interviews were autorecorded so that verbatim transcriptions could be created. Results: Causes of colorectal cancer were categorized into internal and external factors. The majority of respondents agreed that there is an association between Western foods and colorectal cancer. Malaysian traditional diet was not related to colorectal cancer as less preservative agents were used. Malaysian diet preparation consisting of taste of cooking (spicy, salty and sour foods) plus type of cooking (fry, grilled and smoked) were considered causes of colorectal cancer. All respondents changed their dietary pattern to healthy food after being diagnosed with colorectal cancer. Advice from doctors regarding suitable food for colorectal cancer was useful in this regard. Conclusions: Eating outside, use of food flavoring ingredients and preservative agents were considered to be the main factors causing colorectal cancer. All respondents admitted that they changed to a healthy diet after being diagnosed with colorectal cancer.

• 한국자동차공학회논문집
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• 제16권5호
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• pp.22-28
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• 2008

A closed type crankcase ventilation system has been adopted to engines to prevent emission of blow-by gas to atmosphere. In the early closed type crankcase ventilation system, blow-by gas which contains engine lubricating oil is re-circulated into the intake system. The blow-by gas containing oil mist leads to increased harmful emissions and engine problems. To reduce loss of the engine oil, a highly-efficient oil separation device is required. Principle of a cyclone oil separator is to utilize centrifugal force in the separator and, therefore, oil separator designs depend on rotational flow which causes the centrifugal force. In this paper, flow characteristics and oil separation performances for cyclone type designs are calculated with CFD methodology. In the CFD model, oil particle was injected on a inlet surface with Rosin-Rammler distribution and uniform distribution. The major design parameters considered in the analysis model are inlet area, cone length and outlet depth of the oil separator. As results, reducing inlet area and increasing cone length increase oil separation performance. Changes in outlet depth could avoid interference between rotational flow and outlet flow in the cyclone oil separator.

• International journal of advanced smart convergence
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• 제8권1호
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• pp.113-125
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• 2019

The radish skin and radish greens are an edible part of the radish. But they are removed before eating the radish and used as a byproduct or an animal feed material because of their tough and rough texture. This study was conducted to investigate the effect of supercritical heat-treated radish-extract on UV-induced HRM-2 wrinkled mouse animal model on anti-aging wrinkles. Supercritical heat-treated radish-extract was applied on the back of seven-weeks old HRM-2 mice. The effect of HRE on skin thickness, elasticity and wrinkle formation of the mice was observed by using UVB lamp to induce melanogenesis and wrinkle formation. As the result, increased depth of wrinkles was observed in the negative control group in comparison to the normal group. In contrast, decreased depth of wrinkles was observed in the radish-extract-free group compared to the negative control group. In the study of the effect of radish-extract on wrinkle-formation related gene expression and protein what protein expression, MMP-2 and MMP-9 gene expression significantly increased in the negative control group compared to the normal group. The gene expression reduced in dependence to the mass of radish-extract treated. Similar to quantitative results of mRNA expression, the expression of MMP-2 protein increased as a result of UVB-irradiation. The MMP-2 expression was inhibited in dependence to the mass of radish-extract treated. In conclusion, the supercritical heat-treated radish-extract has an effect on improving skin wrinkles not only when it is applied to the skin but also when orally ingested. Thus, it can be effectively used as a composition to health functional products. Therefore we can also conclude that radish a food that does not show any side-effects even upon long-term intake can reduce wrinkle formation as well as improve skin elasticity when taken regularly for a long period.

• Animal Bioscience
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• 제36권8호
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• pp.1252-1262
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• 2023

Objective: Microencapsulation technologies have been developed and successfully applied to protect the probiotic bacterial cells damaged by environmental exposure. This study aimed to investigate the effects of microencapsulation of Lactobacillus plantarum MB001 on the growth performance, ileal nutrient digestibility, jejunal histomorphology and cecal microbiome of broiler chickens in a tropical climate. Methods: A total of 288 one-day-old female broilers (Ross 308) were randomly allocated into 4 groups (6 replicates of 12 birds). Treatments included, i) a basal diet (NC), ii) NC + avilamycin (10 mg/kg) (PC), iii) NC + non-encapsulated L. plantarum MB001 (1×10⁸ colony-forming unit [CFU]/kg of diet) (N-LP), iv) NC + microencapsulated L. plantarum MB001 (1×10⁸ CFU/kg of diet) (ME-LP). Results: Dietary supplementation of ME-LP improved average daily gain, and feed conversion ratio of broilers throughout the 42-d trial period (p<0.05), whereas ME-LP did not affect average daily feed intake compared with NC group. Both N-LP and ME-LP improved apparent ileal digestibility of crude protein and ether extract compared with NC group (p<0.05). The broilers fed ME-LP supplemented diet exhibited a beneficial effect on jejunal histomorphology of villus height (VH), crypt depth (CD) and villus height to crypt depth ratio (VH:CD) of broilers compared to NC group (p<0.05). At the phylum level, Firmicutes was enriched (p<0.05) and Proteobacteria was decreased (p<0.05) only in the ME-LP group. At the genus level, the ME-LP diets increased (p<0.05) the number of both Lactobacillus and Enterococcus compared to NC, PC, and N-LP groups (p<0.05). Conclusion: Microencapsulation assists the efficient functioning of probiotics. ME-LP could be potentially used as a feed additive for improvement of cecal microbiota, gut integrity and nutrient utilization, leading to better performance of broilers.

• 대한화장품학회지
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• 제42권4호
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• pp.367-375
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• 2016

본 연구에서는 락툴로스(lactulose) 51.67%와 갈락토올리고당(galactooligo saccharides) 15.8%로 이루어진 듀올리고(DuOligo)의 섭취를 통하여 피부개선 효능을 조사하였다. 40~60 대의 건강한 여성 37명을 대상으로 대조군(덱스트린)과 실험군(듀올리고군)으로 나누어 각각 8주 동안 섭취 후, 수분보유량, 경표피수 분손실량, 멜라닌지수, 홍반지수와 주름지수를 측정하였다. 그 결과, 듀올리고 섭취 8주 후의 수분 보유량은 대조군에 비하여 수분 보유량이 38.22% 유의적으로 증가하였다(p < 0.01). 대조군의 경피수분손실량은 8주후 $3.39g/h/m^2$로 감소한데 비하여 듀올리고군의 경피수분손실량은 8주후 $5.32g/h/m^2$ 감소하였다. 대조군의 멜라닌 지수는 시간에 따라 그 값이 유의적으로 증가하였으나, 듀올리고군의 멜라닌 지수는 시간에 따른 유의적 차이가 나타나지 않았다. 또한, 듀올리고군은 대조군에 비하여 주름의 총 넓이, 총 주름의 길이, 주름의 수 및 주름의 깊이가 확연하게 감소하였다(p < 0.05). 듀올리고의 피부개선 기능성 소재로서의 응용 가능성을 확인하였다.

• 한국습지학회지
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• 제23권2호
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• pp.189-200
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• 2021

인공습지는 농업용 저수지의 수질개선을 위하여 많은 곳에 적용되고 있다. 인공습지는 수심분포, 유입량 및 유출량, 물흐름 분포, 체류시간, 수질 처리효율, 종횡비, 개방수역/폐쇄수역 구성비 등이 중요한 설계인자이다. 특히, 인공습지 높은 효율 증대를 위해서는 취입보 형식, 유입보, 인입수로 길이, 셀(Cell) 형태, 셀 연결 형태 등의 설계는 매우 중요하다. 본 연구는 농업용 저수지에 조성되어 운영중인 23개 인공습지의 현장조사를 통하여 설계시 고려하여야 할 인자 및 효율적 운영방안을 제시하고자 수행되었다. 인공습지 중에서 비정상적 운영이 나타나는 습지는 수위센서 미작동, 취입보 내부의 유사퇴적 및 기계식 수문틀의 협잡물 문제가 중요한 원인으로 나타났다. 또한, 인입수로의 길이가 길어질수록 취입보 하류부와 상류부의 생태적 단절구간이 늘어나는 것도 문제점으로 분석되었다. 습지 대부분은 2~5개의 셀로 조성되었으며 셀의 크기가 지나치게 클 경우 수리학적 효율이 떨어지고 관리가 어려운 것으로 평가되었다. 작은 규모의 습지에 많은 셀이 존재하는 경우 큰 수두손실로 인하여 적절한 유수흐름이 나타나지 않는 것으로 평가되었다.

• Asian-Australasian Journal of Animal Sciences
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• 제21권4호
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• pp.567-573
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• 2008

This experiment examined the effect of dietary spray-dried bovine colostrum on intestinal histology and organ weights in early-weaned pigs. In a randomised complete block design, twelve 14-day-old weaner pigs were offered a diet containing either 5% spray-dried bovine colostrum or no colostrum (control). Diets were formulated to contain 14.8 MJ/kg DE, 1.26% available lysine and to meet or exceed requirements for other nutrients. Piglets were offered the diets for a period of 14 days. No effect of diet on growth rate or feed intake was observed (p>0.10). Small intestine weight was reduced by 12% in piglets consuming dietary bovine colostrum (p< 0.05). Villous height and crypt depth were increased and decreased, respectively, in the proximal jejunum, mid jejunum and distal ileum of pigs consuming dietary bovine colostrum (p<0.05). Mid-jejunal lamina propria $CD4^+$ and $CD8^+$ T lymphocyte density was increased by 28 and 37%, respectively, in piglets consuming dietary bovine colostrum (p<0.05). Diet did not affect thickness of tunica muscularis externa or tunica submucosa (p>0.10). Collectively, these results suggest a positive effect of dietary bovine colostrum on intestinal morphology and immune status in early-weaned pigs.

• Asian-Australasian Journal of Animal Sciences
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• 제21권12호
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• pp.1773-1778
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• 2008

Two experiments were carried out to study the effects of corticosterone (CORT) administration on intestinal morphology and function of broilers. In both experiments, birds were randomly divided into two equal groups. One group was the control group (CTRL), and the birds were fed with a basal diet. The other was the experimental group (CORT), and the birds were fed with the basal diet plus 30 mg of CORT/kg diet. At 21 days of age, performance, morphological characteristics of intestine, D-xylose level in plasma, activities of digestive enzymes in digesta, digestibility of nutrients and 5-bromo-2-deoxyuridine (BrdUrd)-labeling index of intestinal epithelial cells were determined. CORT administration decreased feed intake, daily gain and feed conversion ratio (p<0.05). CORT also decreased duodenal and jejunal villus height (p<0.05) as well as crypt depth (p<0.05). The D-xylose level in plasma of CORT-treated broilers was lower than that of the control (p<0.05). CORT treatment caused a decrease in apparent digestibility of protein (p<0.05), whereas fat and starch apparent digestibilities were unaffected (p>0.05). CORT administration increased activities of trypsin and amylase (p<0.05), and decreased BrdUrd-labeling index of duodenal and jejunal epithelial cells (p<0.05). In conclusion, CORT administration impaired the normal morphology and absorptive capacity of the small intestine of broiler chickens.

• 한국분무공학회지
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• 제17권2호
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• pp.94-99
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• 2012

The characteristics of spray behavior and injected amount were studied with two types of nozzles for using in a compression ignition engine with dual fuel technology for construction machines. A penetration length of spray tends to shorten due to a decrease of injected amount of a diesel fuel with dual fuel engine application. In order to ignite the gaseous fuel premixed with air during intake process, a diesel fuel, which was compression ignited, needs to penetrate somehow similar depth compared with the case of a diesel fuel-only-injection. In this work, a nozzle with reduced hole diameter and increased number of holes was tested and demonstrated that, compared to diesel 100% case, its penetration lengths are comparable to 74% and 79%, respectively, of those of 100% and 50% supply of a diesel fuel with the baseline nozzle that has four holes and 30.4% increased diameter. This will presumably enhancement the combustion in a dual fuel engine. A design suggestion was also made in this work to achieve similar penetration length of spray with diesel 100% case to prevent combustion from being deteriorated in a dual fuel engine.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2010년도 춘계학술대회 논문집
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• pp.123-125
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• 2010

As the exterior noise emitted by a vehicle is getting more and more attention, simulated pass-by measurements become more important. This well established method provides information about the total noise emitted by the vehicle. For a vehicle manufacturer it is not only interesting to know about the total noise but also to know how this total exterior noise is composed of different contributions, such as for example the contribution of the engine, the intake or exhaust system. Transfer path analysis (TPA) provides a separation of these contributions for each of the pass-by microphones alongside the track. Presented is a method for fast and efficient determination of the contributions of multiple sources using operational transfer path analysis (OTPA). The calculation of the transfer characteristics between the reference measurement points on the vehicle and the corresponding response points of both microphone lines are carried out while operation of the vehicle. As result of the contribution analysis from operational transfer path analysis, the characteristic noise level as function of the covered distance is displayed for all individual sound sources, thus providing in depth information for sound quality engineering.