• Clinical and Experimental Pediatrics
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• v.61 no.10
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• pp.315-321
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• 2018

Purpose: To investigate the effectiveness of transient intubation for surfactant administration and extubated to nasal continuous positive pressure (INSURE) for treatment of respiratory distress syndrome (RDS) and to identify the factors associated with INSURE failure in extremely premature infants. Methods: Eighty-four infants with gestational age less than 28 weeks treated with surfactant administration for RDS for 8 years were included. Perinatal and neonatal characteristics were retrospectively reviewed, and major pulmonary outcomes such as duration of mechanical ventilation (MV) and bronchopulmonary dysplasia (BPD) plus death at 36-week postmenstrual age (PMA) were compared between INSURE (n=48) and prolonged MV groups (n=36). The factors associated with INSURE failure were determined. Results: Duration of MV and the occurrence of BPD at 36-week PMA were significantly lower in INSURE group than in prolonged MV group (P<0.05), but BPD plus death at 36-week PMA was not significantly different between the 2 groups. In a multivariate analysis, a reduced duration of MV was only significantly associated with INSURE (P=0.001). During the study period, duration of MV significantly decreased over time with an increasing rate of INSURE application (P<0.05), and BPD plus death at 36-week PMA also tended to decrease over time. A low arterial-alveolar oxygen tension ratio (a/APO2 ratio) was a significant predictor for INSURE failure (P=0.001). Conclusion: INSURE was the noninvasive ventilation strategy in the treatment of RDS to reduce MV duration in extremely premature infants with gestational age less than 28 weeks.

• Clinical and Experimental Pediatrics
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• v.65 no.4
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• pp.188-193
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• 2022

Background: Respiratory distress syndrome (RDS) is a common cause of hospitalization and death in preterm infants who require surfactant treatment and respiratory support. Purpose: This study aimed to compare the clinical outcomes of minimally invasive surfactant therapy (MIST) and the INtubation, SURfactant administration, and Extubation (INSURE) technique in preterm infants with RDS. Methods: In this clinical trial, 112 preterm infants born at 28-36 weeks of gestation and diagnosed with RDS randomly received 200-mg/kg surfactant by MIST or the INSURE method. In the MIST group, surfactant was administered using a thin catheter (5F feeding tube); in the INSURE group, surfactant was administered after intubation using a feeding tube and the tracheal tube was removed after positive pressure ventilation was started. Nasal continuous positive airway pressure was applied in both groups for respiratory support and the postprocedure clinical outcomes were compared. Results: The mean hospitalization time was shorter for infants in the MIST group than for those in the INSURE group (9.19±1.72 days vs. 10.21±2.15 days, P=0.006). Patent ductus arteriosus was less frequent in the MIST group (14.3% vs. 30.4%, P=0.041). Desaturation during surfactant administration occurred less commonly in the MIST group (19.6% vs. 39.3%, P=0.023). There were no significant intergroup differences in other early or late complications. Conclusion: These results suggest that surfactant administration using MIST could be a good replacement for INSURE in preterm infants with RDS since its use reduced the hospitalization time and the number of side effects.

• Proceedings of the KSR Conference
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• 2008.06a
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• pp.1724-1728
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• 2008

Track circuit is transmitted throughout the rails. In order to insure safe and reliable operation of track circuits, the track and the environment should respect mandatory electrical characteristics. In addition, for cab signalling through track Circuit as per TVM 430, these electrical characteristics should insure the transmission to the train. Track circuits have several operation and safety functions. They can detect the train position and broken rails. When track circuits are used as track to train transmission, they also have to be powered enough to be captured by the train sensors.

• Journal of the Chungcheong Mathematical Society
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• v.3 no.1
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• pp.27-32
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• 1990

In this paper, we obtain conditions which are sufficient to insure convergence of these amarts in the weak topology of E.

• Journal of Sasang Constitutional Medicine
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• v.23 no.1
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• pp.1-7
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• 2011

Reforming the insurance scheme for herbal drugs in the National Health Insurance is a long-cherished desire for Korean Medicine doctors. Because most Korean Medicine doctors distrust the quality of existing insured herbal drugs, which are powdered mixes of each herbal extract, the use and the expenditure of insured herbal drugs have been decreased in the last ten years. To address this, it has been demanded to insure the composite type of herbal preparation, which is the extracted powder of the whole prescription, to the benefit coverage for herbal drugs. Many stake holders, however, have so far been unable to reach an agreement on this. In this situation, Sasang Constitutional prescriptions are expected to make a breach of insuring the composite herbal preparations, because some of them were approved as prescription drugs in 1999. In this review, I discussed the problems of insured herbal drugs, the necessity of insuring the composite herbal preparations and Sasang Constitutional prescriptions, and the tasks of Sasang Constitutional Society to insure them.

• Journal of computational fluids engineering
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• v.17 no.3
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• pp.93-98
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• 2012

The injection molding process is suitable for manufacturing complicated plastic products. As the customer request higher quality products increase, realization of the precise dimensional and shape controls is getting more important. For this purpose it is important to obtain uniform cooling procedure over the whole surface of the high temperature molded plastic. Failure to this may lead to different shrinkage speed, internal stresses and unwanted shape deformations. It is necessary to distribute coolant flow rates to the main channel and to the sub-channels properly to insure uniform cooling process when there are parallel cooling channels. In this study, three-dimensional turbulent flow simulations for representative parallel cooling channels were performed. To insure the intended flow rate to each sub-channels, various shape designs for the channel system were investigated. The results show that as the Reynolds number increases the effect of shape design is more profound. Through the proper flow distribution, uniform cooling effects would be expected.

• 한국기계연구소 소보
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• s.17
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• pp.75-82
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• 1987

Shrink-rings (Stress-rings) are used in the fabrication of powder compaction dies to increase the allowable compaction pressures for a given die material. Optimum Procedures are used to insure that the stress distributions in the die and stress-rings ultilize fully the strength available in each of the die elements. Two criteria for the optimum die design are used: Maximum shear stress limit for one-piece dies and zero tensile stress limit for combined dies. Examples for each case are presented in this paper.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.16 no.27
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• pp.27-34
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• 1993

It is requested to promote technology development and productivity that is way to conquer the competition of technology and quality and pressure of cost caused by a rise in prices. To pace up the market fluctution and the deepening of competion, there need a strategical thoughts of production management. Corporation's efforts concentrated in specific business field are desired to insure the initiative competion. In this paper, the concentration aimed at gaining higher competion is analized in the condition of equal enviornment and/or situation.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.31B no.3
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• pp.39-46
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• 1994

In this paper, three types of parameter update law which can be used in model reference adaptive control are suggested based on speed-gradient algorithm which was introduced by Fradkov. It is shown that the parameter update law which was proposed by Narendra is a special from of these laws and that proposed parameter update laws can insure the global stability under some conditions such as attainability and convexity. We also comment that the transfer function of reference model shoud be positive real for the realization of parameter update law.

• Proceedings of the Korea Concrete Institute Conference
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• 1991.04a
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• pp.117-120
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• 1991

Cracks of concrete structure must be analyzed and estimated synthetically in order to have a maintenance and to insure the safety and the durability of structure. Concrete cracks have to be surveyed with respect to depth, width, shape and direction etc, but crack depth among these items is not measured easily. Occasionally, it needs to measure the crack depth of concrete structure for the purpose of evaulating the safe capacity and the necessity of repair. Therefore, this research is performed to verify the applicability and the accuracy of Ultra-sonic Pulse Velocity Technique(Tester), in non-destructive testing methods of concrete crack depth.