• Investigative Magnetic Resonance Imaging
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• v.22 no.3
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• pp.158-167
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• 2018

Purpose: To investigate the surgical, perfusion, and molecular characteristics of glioblastomas which influence long-term survival after treatment, and to explore the association between MR perfusion parameters and the presence of MGMT methylation and 1p/19q deletions. Materials and Methods: This retrospective study was approved by our institutional review board. A total 43 patients were included, all with pathologic diagnosis of glioblastoma with known MGMT methylation and 1p/19q deletion statuses. We divided these patients into long-term (${\geq}60\;months$, n = 7) and short-term (< 60 months, n = 36) survivors, then compared surgical extent, molecular status, and rCBV parameters between the two groups using Fisher's exact test or Mann-Whitney test. The rCBV parameters were analyzed according to the presence of MGMT methylation and 1p/19q deletions. We investigated the relationship between the mean rCBV and overall survival using linear correlation. Multivariable linear regression was performed in order to find the variables related to overall survival. Results: Long-term survivors (100% [7 of 7]) demonstrated a greater percentage of gross total or near total resection than short-term survivors (54.5% [18 of 33]). A higher prevalence of 1p/19q deletions was also noted among the long-term survivors (42.9% [3 of 7]) than the short-term survivors (0.0% [0 of 36]). The rCBV parameters did not differ between the long-term and short-term survivors. The rCBV values were marginally lower in patients with MGMT methylation and 1p/19q deletions. Despite no correlation found between overall survival and rCBV in the whole group, the short-term survivor group showed negative correlation ($R^2=0.181$, P = 0.025). Multivariable linear regression revealed that surgical extent and 1p/19q deletions, but not rCBV values, were associated with prolonged overall survival. Conclusion: While preoperative rCBV and 1p/19q deletion status are related to each other, only surgical extent and the presence of 1p/19q deletion in GBM patients may predict long-term survival.

• Journal of Environmental Impact Assessment
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• v.24 no.5
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• pp.444-455
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• 2015

In relation to the utilization and disposal of dredged sediment caused by coastal dredging project, we diagnosed the status of legal standard and system, and proposed the improvement plan. Dredging costal sediment distinguished the usage and the disposal by the Standard for the Beneficial Usage of Dredged Sediment. The site where disposal has been completed could be used as a site for developmental project. In case of the usage of dredged sediment for reclamation, we found that the adaptation of the Standard for Beneficial Usage of Dredged Sediment is appropriate for reclamation considering the characteristic of soil, the differences of variables, and the distinction of standard analysis methods. The current the Standard for Beneficial Usage of Dredged Sediment requires the improvement with the usage of dredging coastal sediment in the following. First, the Standard needs to include the standard of the discrimination for reclamation. Second, the current Standard is necessary to be divided by two levels, it needs to be mitigated considering human health risk. Third, it is necessary to consider both the marine environmental impact assessment and mitigation plan near coastal dredging area.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.4
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• pp.556-566
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• 2016

This study examined the influence of satisfaction with clinical practice and the image of nurses on the nursing professionalism of nursing students. The subjects were 184 nursing students in B city who had experienced clinical practice. The data were collected from November 15 to December 15, 2014 and, analyzed using a t-test, ANOVA, Scheff's test, Pearson's correlation coefficients and multiple regression. Significant differences in the nursing professionalism by gender, religion, age, and school record were observed. Nursing professionalism was positively related to the satisfaction with clinical practice. In addition, there was a positive correlation between the nursing professionalism and image of nurses. Meaningful variables that influenced the nursing professionalism were satisfaction with the contents of clinical practice, image of nurses, satisfaction with the course of clinical practice, satisfaction with the environment of clinical practice, and school record. These factors comprised 75.8% of the total variance in the nursing professionalism of nursing students, and the satisfaction with contents of clinical practice was the most influential factor. In conclusion, to increase the nursing professionalism of nursing students, it is necessary to develop educational programs and institutional strategies to improve the satisfaction with clinical practice and the image of nurses.

• Journal of Digital Convergence
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• v.14 no.2
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• pp.315-324
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• 2016

The purpose of the study are expected to provide some basic information on counseling, diagnosis and treatment planning for patients related to teeth care. A self-reported questionnaire was filled out by 320 subjects in Seoul and Gyeonggi from May to August, 2015 after permission from Institutional Review Board (IRB). Except 18 copies, 302 data were analyzed using SPSS WIN 19.0 program. The questionnaire consisted of four questions of the general characteristics of the subjects, ten questions of the awareness toward of subjective teeth, five questions of the influence of teeth on appearance, and ten questions of self-esteem. The dependent variables made a 23.4% prediction of self-esteem. If they have higher education(p<0.001), influence of teeth on appearance(p<0.001) and the awareness toward of subjective teeth(p<0.001) had significant influence on self-esteem. The findings suggest that heightened subjective awareness toward teeth seems to be of use for the improvement of self-esteem. Therefore it's required to make an effort to take good care of teeth in terms of color or arrangement as well as oral health.

• Journal of Pharmacopuncture
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• v.19 no.3
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• pp.197-206
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• 2016

Introduction: This study aims to investigate the effects of acupuncture stimulation on the radial artery's pressure pulse wave, along with various hemodynamic parameters, and to explore the possible underlying mechanism of pulse diagnosis in healthy participants in their twenties. Methods and analysis: This study is a prospective, single-arm, exploratory clinical study. A total of 25 healthy participants, without regard to gender, in their twenties will be recruited by physicians. Written informed consent will be obtained from all participants. The participants will receive acupuncture once at ST36 on both sides. The radial arterial pulse waves will be measured on the left arm of the subjects by using an applicable pulse tonometric device (KIOM-PAS). On the right arm (appearing twice), electrocardiogram (ECG), photoplethysmogram (PPG), respiration and cardiac output (CO) signals, will be measured using a physiological data acquisition system (Biopac module), while the velocity of blood flow, and the diameter and the depth of the blood vessel will be measured using an ultrasonogram machine on the right arm (appearing twice). All measurements will be conducted before, during, and after acupuncture. The primary outcome will be the spectral energy at high frequencies above 10 Hz ($SE_{10-30Hz}$) calculated from the KIOM-PAS device signal. Secondary outcomes will be various variables obtained from the KIOM-PAS device, ECG, PPG, impedance cardiography modules, and an ultrasonogram machine. Discussion: The results of this trial will provide information regarding the physiological and the hemodynamic mechanisms underlying acupuncture stimulation and clinical evidence for the influence of acupuncture on the pressure pulse wave in the radial artery. Ethics and dissemination: This study was approved by the Institutional Review Board (IRB) of Kyung Hee University's Oriental Medical Center, Seoul, Korea (KOMCIRB-150818-HR-030). The study findings will be published in peer-reviewed journals and presented at national and international conferences. Trial registration number: This trial was registered with the Clinical Research Information Service (CRIS) at the Korea National Institute of Health (NIH), Republic of Korea (KCT0001663), which is a registry in the World Health Organization's (WHO's) Registry Network.

• Journal of the Korean Society for Library and Information Science
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• v.53 no.4
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• pp.5-22
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• 2019

The purpose of this study is to analyze the factors that hinder the role recognition and role performance of teacher librarians and suggest some improvement methods. For this purpose, a questionnaire was conducted among 41 persons who participated in the first-level qualification training for teachers librarians at K University Secondary Teacher Training Institute in 2019.The results showed that there was a difference between the expected role and the execution role of the teacher librarians. In other words, teacher librarians recognize that they should teach information literacy as instructors and operate library-based instruction and cooperative classes as teaching partners. However, the most frequently played roles are reading education and library use education. They recognizes the cause as institutional limitations, such as the absence of a national level curriculum and the ambiguity of the role of specialists in school libraries. And it is perceived as a real problem such as the lack of partnership and recognition of their peers. Among the variables of teacher librarians, the higher their educational level, the more they perceived their peers as teachers. Based on this, some suggestions for strengthening the role of the teacher librarians' instructor and teaching partner were proposed in terms of including cross-curricular subjects of information literacy education, analyzing jobs and establishing scholarship system for school libraries.

• Journal of the Korean Regional Science Association
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• v.34 no.4
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• pp.3-18
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• 2018

These days, regional innovation draws more attention than ever as a growth engine for regional economies, and governments put a variety of efforts to establish Regional Innovation systems(RISs). In this circumstance, this study aims to analyze types of RISs and the combinations of the factors influencing innovation performance as measured by patent application. Most of previous works have depended on case-oriented or variable-oriented strategy to classify types of RISs or to analyze the effects on performance of innovation factors, having some limitations: Variable-oriented approaches fail to capture complex combinatory effects of factors, while case-oriented approaches tend to depend on subjective interpretation. This study made use of the recently proposed fs/QCA(Fuzzy-set Qualitative Comparative Analysis) to overcome the limitations of those strategies. Based on the theory of RIS, three factors for regional innovation-input, infrastructure, and network-are used to classify 16 Korean Provinces. The results show that eight types of regional innovation types are identified, and that most of the regions are classified into either IN-type, equipped with high levels of Input and Network, or F-type, with high levels of infrastructure. In addition, applying seven sub-variables of the three factors to the fussy-set combination factor analysis, we examine a combination of factors influencing patent application. The results show that regions with high levels of R&D expense, valid patent, industry-academia cooperation, IP budget, and TLO values, and low IP capital almost always have a high level of patent application. Therefore, for regional innovation, the public sector needs to provide institutional support for R & D personnel training. It is also important to for both the public and the private sectors to make efforts to stimulate IP financing.

• Journal of the Korea Convergence Society
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• v.10 no.9
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• pp.75-84
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• 2019

This study aimed to identify the factors affecting the nursing performance and the convergence relationships of leisure satisfaction, job stress, and nursing performance among nurses. Participants included 150 nurses working at 2 hospitals in C city from August 3 to September 15, 2018. The data were analyzed using descriptive statistics, independent t-test, one-way ANOVA with Scheffe's test, Pearson correlation coefficients, and multiple regression by SPSS 23.0 program. Nursing performance were significantly differences in age (F=4.78, p=.003), marital status (F=2.74, p=.007), length of clinical career (F=3.34, p=.012), and health condition (F=5.23, p=.002). Nursing performance was a positively correlated with leisure satisfaction (r=.32, p<.001) and a negatively correlated with job stress (r=-19, p=.020), and job stress was a negatively correlated with leisure satisfaction (r=-.32, p=.005). The factors affecting the nursing performance of clinical nurses were age (${\beta}=.20$, p=.008) and leisure satisfaction (${\beta}=.28$, p<.001), and these variables explained about 19.6% of the variance in nursing performance. In order to improve nursing performance, it is necessary to provide working environment and institutional support for increasing leisure satisfaction and reducing job stress and age-differentiated approaches.

• The Journal of the Korea Contents Association
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• v.21 no.10
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• pp.679-689
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• 2021

The objective of this study is to verify the moderated mediating effects according to the severity level of a disability as well as the mediating effects of job security in the relationship between difficulties in the workplace of the disabled wage workers caused by the COVID-19 pandemic and their life satisfaction. As a result of analysis using SPSS ver. 25 and PROCESS macro, the difficulties within the workplace caused by the COVID-19 pandemic had a negative influence on life satisfaction through the job security of the disabled wage worker. In other words, it was revealed that the level of difficulties being faced by the disabled wage workers, which were caused by the COVID-19 pandemic, hinders their life satisfaction through job security. In addition, no moderating effect according to the severity level of disability was identified in the relationship between these variables. This is translated that difficulties in the workplace caused by the COVID-19 pandemic reduce job security and life satisfaction of the disabled wage workers regardless of the severity level of the disability. Based on the results thus far, this study further discussed the institutional implications for promoting the job security and life satisfaction of the disabled wage workers under the COVID-19 pandemic situation.

• Journal of Chest Surgery
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• v.55 no.1
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• pp.10-19
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• 2022

Background: According to the eighth TNM (tumor-node-metastasis) staging system, the presence of separate tumor nodules in the same lobe is designated as a T3 descriptor. However, it remains unclear whether adjuvant chemotherapy confers survival advantages in this setting. Methods: We retrospectively identified 142 pathologic T3N0M0 patients with additional pulmonary nodules in the same lobe from a single-institutional database from 2004 to 2019. The main outcomes were overall survival and recurrence-free survival. Multivariable Cox regression was used to identify the benefit of adjuvant chemotherapy while adjusting for other variables. Results: Sixty-one patients received adjuvant chemotherapy (adjuvant group) and 81 patients did not receive adjuvant therapy after surgery (surgery-only group). There were no demonstrable differences between the 2 groups regarding hospital mortality and postoperative complications, indicating that treatment selection had not significantly occurred. However, the use of adjuvant chemotherapy was associated with improved 5-year overall survival (70% vs. 59%, p=0.006) and disease-free survival (60% vs. 46%, p=0.040). A multivariable Cox model demonstrated that adjuvant chemotherapy was associated with a survival advantage (adjusted hazard ratio, 0.54; p<0.001). In exploratory analyses of subgroups, the effect of adjuvant chemotherapy seemed to be insufficient in those with small main tumors (<4 cm). Conclusion: Adjuvant chemotherapy was associated with better survival in T3 cancers with an additional tumor nodule in the same lobe. However, the role of adjuvant chemotherapy in patient subgroups with small tumors or those without risk factors should be determined via large studies.