• Title/Summary/Keyword: Inoperable

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Deep vein thrombosis caused by malignant afferent loop obstruction

  • Kang, Eun Gyu;Kim, Chan;Lee, Jeungeun;Cha, Min-uk;Kim, Joo Hoon;Park, Seo-Hwa;Kim, Man Deuk;Lee, Do Yun;Rha, Sun Young
    • Journal of Yeungnam Medical Science
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    • v.33 no.2
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    • pp.166-169
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    • 2016
  • Afferent loop obstruction following gastrectomy is a rare but fatal complication. Clinical features of afferent loop obstruction are mainly gastrointestinal symptoms. A 56-year-old female underwent radical total gastrectomy with Roux-en-Y esophagojejunostomy for treatment of advanced gastric cancer. After fourteen months postoperatively, she showed gradual development of edema of both legs. Computed tomography (CT) scan showed disease progression at the jejunojejunostomy site and consequent dilated afferent loop, which resulted in inferior vena cava (IVC) compression. A drainage catheter was placed percutaneously into the afferent loop through the intrahepatic duct and an IVC filter was placed at the suprarenal IVC, and self-expanding metal stents were inserted into bilateral common iliac veins. With these procedures, sympotms related with afferent loop obstruction and deep vein thrombosis were improved dramatically. The follow-up abdominal CT scan was taken 3 weeks later and revealed the completely decompressed afferent loop and improved IVC patency. Surgical treatment should be considered as the first choice for afferent loop obstruction; however, because it is more immediate and less invasive, non-surgical modalities, such as percutaneous catheter drainage or stent placement, can be effective alternatives for inoperable cases or risky patients who have severe medical comorbidities.

Second primary cancer in reconstructed neopharynx: a case report (재건된 새 인두의 이차암에 대한 증례 보고서)

  • Kang, Karam;Han, Hye Min;Kim, Hyunjung;Baek, Seung-Kuk;Jung, Kwang Yoon
    • Korean Journal of Head & Neck Oncology
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    • v.33 no.2
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    • pp.89-93
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    • 2017
  • Background. Ever since the first report of deltopectoral flap in pharyngo-esophageal reconstruction in 1965, various methods of flap reconstruction have been introduced, allowing surgical eradication of tumors that were once thought to be inoperable. Despite these advancement, many literatures emphasize distant metastasis and second primary malignancies as the most important factors that contribute to the low 5-year survival rate of the patients. Specific consensus about defining second primary cancer is still debatable, due to small number of reports regarding second primary tumors arising in flaps used for reconstruction of defects in the head and neck region. Case. We report a case of a 72-year-old male patient who, under the diagnosis of hypopharyngeal cancer, underwent total laryngectomy with partial pharyngectomy, extended right radical neck dissection with extended left lateral neck dissection, right hemithyroidectomy and radial forearm free flap reconstruction on June 16, 2003. After 37 cycles of radiation therapy, the patient exhibited no sign of recurrence. The patient revisited our department on June 14, 2016 with chief complaint of dysphagia that started two months before the visit. Radiologic studies and histology revealed squamous cell carcinoma in neopharynx, one that had been reconstructed with forearm free flap. Conclusion. Until now, only a handful of reports regarding patients with second primary cancer in reconstructed flaps have been described. Despite its rarity, diagnostic criteria for second primary cancer should always kept in consideration for patients with recurred tumor.

Experience of Reconstruction of an Extensive Chest Wall Defect with Extended External Oblique Musculocutaneous Flap (거대 흉벽 결손에 대한 확장 외복사근 근피판을 이용한 흉벽재건 치험례)

  • Kim, Dae-Hee;Kim, Chung-Hun;Song, Seung-Yong
    • Archives of Plastic Surgery
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    • v.37 no.3
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    • pp.277-280
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    • 2010
  • Purpose: The resection of locally advanced or recurred breast cancers frequently result in large chest wall defects and it leads to a great challenges to cover. Generally simple skin grafts are not a practical option for patients because of their poor cosmetic appearance and prognosis. The latissimus dorsi and rectus abdominis musculocutaneous flap have traditionally been recommended for closure of these large defects. Though the cosmetic result of reconstruction using these flaps is often excellent, but has significant drawbacks. Therefore, we thought that chest wall reconstruction using the external oblique musculocutaneous flap can be an alternative method for extensive chest wall defect related to large, locally advanced breast carcinoma. Methods & Results: We present a case of a 50-year-old Korean female, refered to our department with a left breast tumor for 10 months. CT demonstrate a large tumor on the left anterior chest wall and multiple nodules of varying size in the cervical areas and liver. FDG-PET showed areas of hot uptake throughout the left chest wall, mediastinum and liver. Biopsy was consistent with invasive ductal carcinoma (Grade III). The initial tumor was considered inoperable, so a series of chemotherapy was initiated. Though the size of the breast mass was slightly decreased, the patient continued to suffer from purulent discharge, unpleasant odor and contact bleeding of the mass, the salvage mastectomy was performed. Conclusion: We could reconstruct $23{\times}16\;cm$ sized large chest wall defect, resulting from the resection of a locally advanced breast carcinoma, using an external oblique musculocutaneous flap successfully. Immediate postoperatively checked flap was healthy. Overall result was good without any significant complications and discharged 3 weeks after operation.

Treatment outcomes of extended-field radiation therapy for thoracic superficial esophageal cancer

  • Lee, Doo Yeul;Moon, Sung Ho;Cho, Kwan Ho;Kim, Tae Hyun;Kim, Moon Soo;Lee, Jong Yeul;Suh, Yang-Gun
    • Radiation Oncology Journal
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    • v.35 no.3
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    • pp.241-248
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    • 2017
  • Purpose: To evaluate the efficacy and safety of extended-field radiation therapy for patients with thoracic superficial esophageal cancer (SEC). Materials and Methods: From May 2007 to October 2016, a total of 24 patients with thoracic SEC (T1a and T1b) who underwent definitive radiotherapy and were analyzed retrospectively. The median total radiotherapy dose was 64 Gy (range, 54 to 66 Gy) in conventional fractionation. All 24 patients received radiotherapy to whole thoracic esophagus and 23 patients received elective nodal irradiation. The supraclavicular lymph nodes, the celiac lymph nodes, and both of those nodal areas were included in 11, 3, and 9 patients, respectively. Results: The median follow-up duration was 28.7 months (range 7.9 to 108.0 months). The 3-year overall survival, local control, and progression-free survival rates were 95.2%, 89.7%, and 78.7%, respectively. There were 5 patients (20.8%) with progression of disease, 2 local failures (8.3%) and 3 (12.5%) regional failures. Three patients also experienced distant metastasis and had died of disease progression. There were no treatment-related toxicities of grade 3 or higher. Conclusion: Definitive extended-field radiotherapy for thoracic SEC showed durable disease control rates in medically inoperable and endoscopically unfit patients. Even extended-field radiotherapy with elective nodal irradiation was safe without grade 3 or 4 toxicities.

Giant Cell Tumor of the Cervical Spine - Case Report - (경추에 발생한 거대 세포종 - 증례 보고 -)

  • An, Ki-Chan;Chung, Kyung-Chil;Kim, Yoon-Jun
    • The Journal of the Korean bone and joint tumor society
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    • v.12 no.1
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    • pp.57-62
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    • 2006
  • Giant cell tumors are potentially malignant tumors in vertebrae, affecting frequently difficult to diagnose and are often inoperable. So it will be treated using radiation because of their high recurrence rate and the mechanical compression of spinal cord, but many surgeons described tumors of the vertebra, and the affected vertebral body can be treated using radical or near to total excision, with anteroposterior vertebral fusion or instrumentation of the spine. we report a case of giant cell tumor affecting the third cervical vertebra which caused neck pain and destroyed the vertebra body had treated using radical excison with fusion of posterior arch using instrumentation of the spine together with a literature review.

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Redundancy operation method for a distributed public address system (분산형 전관방송 시스템의 이중화 운영 방법)

  • Ryu, Taeha;Kim, Seungcheon
    • Journal of the Korea Convergence Society
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    • v.11 no.8
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    • pp.47-53
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    • 2020
  • In the case of a failure due to equipment deterioration in the public address system or a worker's mistake during construction, broadcasting becomes impossible. In this situation, we have designed a more advanced management broadcast system that can broadcast. The broadcasting service is operated using main broadcasting device, and local broadcasting device operates separately only in the local area. If the main broadcasting device becomes inoperable, the procedure for transferring the control activates the device with the local broadcasting devices based on data backed up by the main controller. This paper proposes an improved method of the conventional emergency broadcasting device duplication method. The existing method could not use the standby equipment in the normal state, but in the proposed method, the standby equipment can be used as local broadcasting equipment in usually. This method enables stable system operation while minimizing resource waste due to redundant configuration of expensive devices.

The Modified Method of Splenic Irradiation (초음파를 이용한 비장의 조준법)

  • Chung, Su-Mi;Jang, Hong-Seok;Choi, Ihl-Bohng;Kim, Choon-Yul;Bahk, Yong-Whee
    • Radiation Oncology Journal
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    • v.6 no.2
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    • pp.259-262
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    • 1988
  • Splenic irradiation in chronic myelogenous leukemia is reserved for patients who have painful splenemegaly despite chemotherapy and/or inoperable splenomegaly because of huge size. The role of splenic irradiation is diminution of painful splenomegaly and indirect effect of splenic irradiation on unirradiated hematopoietic and lymphoreticular tissue such as reduction of leukocyte count and increase of hemoglobin level. We report on a useful clinical method for splenic irradiation in chronic myelogenous leukemia. We have used sonography as the tool of simulation. The portal size using modified method is smaller than the field size of conventional simulation, and so this method suggests that useful to irradiation of huge splenomegaly, effective shielding of critical organ and the downfall of complication during irradiation of spleen.

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Long Term Follow-Up after Skull Base Reconstrucion (두개저부 종양 절제 및 재건 후 장기 추적관찰)

  • Jin, Ung Sik;Won Minn, Kyung;Heo, Chan Yeong
    • Archives of Plastic Surgery
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    • v.32 no.2
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    • pp.175-182
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    • 2005
  • Skull base tumors have been determined inoperable because it is difficult to accurately diagnose the extent of the involvement and to approach and excise the tumor safely. However, recently, the advent of sophisticated diagnostic tools such as computed tomography and magnetic resonance imaging as well as the craniofacial and neurosurgical advanced techniques enabled an accurate determination of operative plans and safe approach for tumor excision. Resection of these tumors may sometimes result in massive and complex extirpation defects that are not amenable to local tissue closure. The purpose of this study is to analyze experiences of skull base reconstruction and to evaluate long term survival rate and complications. All cranial base reconstructions performed from July 1993 to September 2000 at Department of Plastic and Reconstructive Surgery of the Seoul National University Hospital were observed. The medical records were reviewed and analysed to assess the location of defects, reconstruction method, existence of the dural repair, history of preoperative radiotherapy and chemotherapy, complications and causes of death of the expired patients. There were 12 cases in region II, 8 cases in region I and 1 case in region III according to the Irish classification of skull base. Cranioplasty was performed in 4 patients with a bone graft and microvascular free tissue transfer was selected in 17 patients to reconstruct the cranial base and/or mid-facial defects. Among them, 11 cases were reconstructed with a rectus abdominis musculocutaneous free flap, 2 with a latissimus dorsi muscluocutaneous free flap, 1 with a fibular osteocutaneous free flap, 2 with a scapular osteocutaneous free flap, and 1 with a forearm fasciocutaneous free flap, respectively. During over 3 years follow-up, 5 patients were expired and 8 lesions were relapsed. Infection(3 cases) and partial flap loss(2 cases) were the main complications and multiorgan failure(3 cases) by cancer metastasis and sepsis(2 cases) were causes of death. Statistically 4-years survival rate was 68%. A large complex defects were successfully reconstructed by one-stage operation and, the functional results were also satisfactory with acceptable survival rates.

Clinical Impact of Palliative Treatment Using Octreotide for Inoperable Malignant Bowel Obstruction Caused by Advanced Urological Cancer

  • Kubota, Hiroki;Taguchi, Kazumi;Kobayashi, Daichi;Naruyama, Hiromichi;Hirose, Masahito;Fukuta, Katsuhiro;Kubota, Yasue;Yasui, Takahiro;Yamada, Yasuyuki;Kohri, Kenjiro
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7107-7110
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    • 2013
  • Malignant bowel obstruction (MBO), an occasional complication in patients with advanced urological cancer, causes gastrointestinal symptoms such as nausea and vomiting leading to suffering which severely impairs quality of life (QOL). Drug therapy, especially octreotide, a synthetic analog of somatostatin, is reportedly effective in controlling the symptoms of MBO. In the present study, we administered octreotide to urological cancer patients with MBO and evaluated the improvement of subjective symptoms, oral intake, and nasogastric intubation. Fourteen terminally ill urological cancer patients suffering with MBO were included (age range 55-92, 10 male, 4 female). Octreotide was administered at $300{\mu}g/day$ to those patients subcutaneously as a continuous injection. Significant improvements in subjective symptoms were observed in thirteen patients (92.8%), and ten patients (71.4%) were able to resume oral intake. Four patients required nasogastric drainage before the administration of octreotide, but nasogastric intubation was discontinued in all these cases after the use of octreotide. Early initiation of octreotide resulted in better improvement of MBO symptoms, and no adverse event was observed in any of the patients. These results revealed that $300{\mu}g/day$ dose of octreotide is safe and effective for managing gastrointestinal symptoms of terminally ill urological cancer patients with MBO. We also recommend starting the treatment with ocreotide as soon as MBO is diagnosed.

The Implementation of Stmart Phone Edition based on Embedded Linux (임베디드 리눅스 기반의 스마트폰 에디션 구현)

  • Kim Do-Hyung;Yun Min-Hong;Kim Sun-Ja;Lee Cheol-Hoon
    • The KIPS Transactions:PartA
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    • v.12A no.7 s.97
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    • pp.597-604
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    • 2005
  • The paper describes implementation of smartphone edition based on embedded Linux, which is composed of smartphone middleware and basic applications. Existing smartphone platforms entails loyalty expenses and has difficulties on customization due to the closed policy of their source codes. Although GPE - based on embedded Linux has solved the loyalty issues, other problems are remained unsolved. Since GPE has been designed for relatively large PDA-level devices, applications are generally inoperable under the condition of small LCD size and input methods without touch-screen; the condition is typical limitations of the smartphones. In the implemented smartphone edition of the paper no loyalty is required, because the smartphone edition is based on embedded Linux. It also supports keypad-only operating functionality such as moving between folders or running applications with operations. Besides, it provides more user-friendly environment to use the smartphone editionscreen interfaces and indicatorsto those of the regular cellular phones.