• Journal of Korean Neurosurgical Society
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• v.56 no.1
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• pp.71-74
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• 2014

Cancer-related facial pain refractory to pharmacologic management or nondestructive means is a major indication for destructive pain surgery. Stereotactic mesencephalotomy can be a valuable procedure in the management of cancer pain involving the upper extremities or the face, with the assistance of magnetic resonance imaging (MRI) and electrophysiologic mapping. A 72-year-old man presented with a 3-year history of intractable left-sided facial pain. When pharmacologic and nondestructive measures failed to provide pain alleviation, he was reexamined and diagnosed with inoperable hard palate cancer with intracranial extension. During the concurrent chemoradiation treatment, his cancer-related facial pain was aggravated and became medically intractable. After careful consideration, MRI-based stereotactic mesencephalotomy was performed at a point 5 mm behind the posterior commissure, 6 mm lateral to and 5 mm below the intercommissural plane using a 2-mm electrode, with the temperature of the electrode raised to $80^{\circ}C$ for 60 seconds. Up until now, the pain has been relatively well-controlled by intermittent intraventricular morphine injection and oral opioids, with the pain level remaining at visual analogue scale 4 or 5. Stereotactic mesencephalotomy with the use of high-resolution MRI and electrophysiologic localization is a valuable procedure in patients with cancer-related facial pain.

• Journal of Hospice and Palliative Care
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• v.12 no.2
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• pp.49-55
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• 2009

Self expandable metal stent (stent) implantation of upper gastrointestinal (UGI) tract is now widely accepted for the palliation of obstructive symptoms caused by inoperable malignant UGI obstruction. With the technical progress and accumulation of clinical experiences, it became possible to perform the procedure easily, safely and effectively. However, clinicians should pay attention to the post-procedural care, because early or late complications such as ulceration, pain, bleeding, food impaction, perforation, migration or in-stent tumor growth could occur. In this review, several topics about stent placement in the UGI tract are discussed, such as major indications for stenting, kinds of stents, and post-procedural management.

• Transactions of the Korean hydrogen and new energy society
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• v.21 no.5
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• pp.355-363
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• 2010

High purity hydrogen, 97-99 vol.%, with CO at just ppm levels was obtained in a fixed bed of iron oxide employing the steam-iron cycle operation with reduction at 823K and oxidation in a steam-$N_2$ mixture at 773K TGA experiments indicated that temperature of the reduction step as well as its duration are important for preventing carbon build-up in iron and the intrusion of $CO_2$ into the hydrogen product. At a reduction temperature of 823K, oxide reduction by $H_2$ was considerably faster than reduction by CO. If the length of the reduction step exceeds optimal value, low levels of methane gas appeared in the off-gas. Furthermore, with longer durations of the reduction step and CO levels in the reducing gas greater than 10 vol.%, carbidization of the iron and/or carbon deposition in the bed exhibited the increasing pressure drop over the bed, eventually rendering the reactor inoperable. Reduction using a reducing gas containing 10 vol.% CO and a optimal reduction duration gave constant $H_2$ flow rates and off-gas composition over 10 redox reaction cycles.

• Journal of Chest Surgery
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• v.14 no.4
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• pp.324-330
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• 1981

This is a clinical evaluation of 43 primary lung cancer partients who were admitted at Chest Surgery department of Jeonbug National University Hospital from January 1975 to June 1980. The ratio of male to female was 13: 1 and the age at the time of diagnosis is peak during fourth and fifth decade. The major symptoms were cough, chest pain or discomfort, bloody sputum, and dyspnea. Histological diagnosis was squamous cell carcinoma in 30%, undifferentiate cell carcinoma in 23%, adenocarcinoma in 7%, alveolar cell carcinoma in 9% and undetermined histologic type in 30%. The most frequently involved lobe of primary lung cancer was both upper lobe bronchus and the next was stem bronchus. Only six among the 43 cases who had sputum cytology were positive for malignant cell and eleven among the 16 cases who had bronch oscopy perform were histologically malignancy. Among 43 cases, 15 cases were inoperable, 5 cases refused to operation and the operation was per. formed in 23 cases. Seventeen of the 23 cases with operation had resection, 6 with pneumonectomy, 9 with lobectomy and 2 with partial resection, and the others were unresectable.

• Journal of Chest Surgery
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• v.18 no.4
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• pp.844-848
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• 1985

Mediastinal tumors which are originated in mediastinum or probably metastasized from other organs have long fascinated the surgeon because of difficulty of diagnosis and treatment. This report is the analysis of the 26 cases of mediastinal tumors, experienced in the Department of the Thoracic and Cardiovascular Surgery, Chosun University Hospital from January 1978 to January 1985. The result are as follows; 1. The age distribution was 10 months to 68 years old and the average mean age was 34.7 years old. 2. Subjective symptom were as follows: Dyspnea [69.2%], Coughing [42.3%], Chest pain [30.8%], Back pain [15.4%] and Numbness of extremities [15.4%]. Objective signs were as follows: Decreased breathing sound [53.3%], Pleural effusion and hemothorax [34.6%], Palpable neck mass [34.6%], SVC Syndrome [19.4%] and Bloody sputum [15.4%]. But, there were no definitive symptoms in 2 cases. 3. The malignant tumors were 19 cases [73.1%]. 4. The germ cell tumors were 2 cases [7.7%], the neurogenic tumor were 3 cases [11.5%], lymphoma were 8 cases [30.8%], thymoma were 2 cases [7.7%], mesenchymal tumor was 1 case [3.8%], cyst was 1 case [3.8%] and carcinoma were 5 cases [19.2%] among the 23 cases, histologically analyzed. 5. The successful complete removal was done in 5 cases among 7 cases of benign tumors. In malignant cases, the surgical removal had been 7 cases and inoperable cases were treated to radiation and chemotherapy.

• Nuclear Engineering and Technology
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• v.51 no.3
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• pp.676-682
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• 2019

After the Fukushima Daiichi accident, there has been an increasing preference for passive safety features in the nuclear power industry. Some passive safety systems require limited active components to trigger subsequent passive operation. Under very serious accident conditions, passive safety features could be rendered inoperable or damaged. This study evaluates (i) the performance and effectiveness of the passive safety features of iPOWER (innovative Power Reactor), and (ii) whether a severe accident condition could be reached if the passive safety systems are damaged, namely the case of heat exchanger tube rupture. Analysis results show that the reactor coolant system remains in the hot shutdown condition without operator actions or electricity for over 72 h when the passive auxiliary feedwater systems (PAFSs) are operable without damage. However, heat exchanger tube rupture in the PAFS leads to core damage after about 18 h. Such results demonstrate that, to enhance the safety of iPOWER, maintaining the integrity of the PAFS is critical, and therefore additional protections for PAFS are necessary. To improve the reliability of iPOWER, additional battery sets are necessary for the passive safety systems using limited active components for accident mitigation under such extreme circumstances.

• Progress in Superconductivity and Cryogenics
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• v.25 no.1
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• pp.6-10
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• 2023

2 K superfluid helium cryogenic system is the crucial component of many large accelerators. When the cryogenic system is operating at 2K@3129Pa, many room-temperature parts are connected to superfluid helium via tubes. Air Leakage in these connections may lead to air contamination of the cryogenic system. Air contamination may cause equipment failure in cryogenic systems and, in extreme cases, render the entire accelerator system inoperable. Helium guard is a technique that guards against air contamination of these sub-atmospheric pressure connections in 2 K superfluid helium cryogenic system. This paper introduces a typical 2 K cryogenic distribution design for large accelerators, and make risk analysis of air contamination. Finally, the analysis of specific leakage points and detailed engineering design are presented, which may be used as a reference when designing of a 2 K superfluid helium cryogenic distribution system.

• Journal of Digestive Cancer Research
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• v.6 no.1
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• pp.16-24
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• 2018

Gastric cancer is not a single, uniform disease, but rather heterogeneous in nature. It is generally not possible to cure patients with inoperable advanced or metastatic stomach cancer. In the absence of chemotherapy, the median survival time is 3 to 6 months. Therefore, several studies have confirmed the superiority of chemotherapy to the best supportive treatment, in terms of improving the quality of life and prolonging life. Various chemotherapies have been used in the past to treat advanced gastric cancer. Recently, various target therapies and immunotherapy have been introduced. However, compared to other malignancies, the quality of life and life expectancy remain relatively poor in patients with gastric cancer. We expect to overcome these difficulties in the future, with better elucidation of the molecular biology of gastric cancer.

• Korean Journal of Head & Neck Oncology
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• v.40 no.1
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• pp.7-13
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• 2024

The current standard of treatment for differentiated thyroid cancer is surgical resection followed by radioactive iodine therapy according to the recurrence risk. However, external beam radiotherapy may be recommended in limited cases where surgical resection is impossible or residual gross lesion remains or the aforementioned standard therapy is deemed insufficient in achieving local control. We report a case of 59 year old patient who presented with advanced papillary thyroid carcinoma of right neck but was unable to receive surgical resection due to underlying Eisenmenger syndrome. He received radiation therapy of 67.5 Gy in 30 fractions with palliative aim with no further treatment and has been maintaining long-term stable disease state for 38 months. Herein, we report a rare case of palliative aim radiation therapy alone for advanced papillary thyroid carcinoma with literature review.

• Journal of the Korean Society of Industry Convergence
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• v.23 no.5
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• pp.789-798
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• 2020

This paper considers the development of the dynamic analysis model and simulation-based operation safety estimation of A-Frame to be applied to the test evaluation support vessel for real sea test. The support vessel will be manufactured by modifying the existing offshore support vessel. Also, development and installation of various sensors and supporting facilities for test evaluation are under preparation. Among these facilities, A-Frame is an equipment that transfers marine equipment from ship deck to the sea floor, and is being designed to transfer up to 50 ton class equipment. However, the A-Frame is a moving equipment using hydraulic cylinders. When the 50 ton equipment is attached and transferred to A-Frame, the buckling of cylinders may occur or A-Frame becomes inoperable due to the influence of huge inertia. For this reason, safety verification should be performed using dynamic analysis techniques that can take into account huge inertia forces in the design of A-Frame. Therefore, in this study, A-Frame and ship behavior were modeled using dynamic analysis method, and the applied loads of various equipment including hydraulic cylinder of A-Frame was measured and the operation safety review was performed.