• The Journal of Asian Finance, Economics and Business
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• v.1 no.4
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• pp.23-27
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• 2014

The authors emphasize that the Republic of Kazakhstan is characterized by significant differences in the level of innovation capacity of regions. This article summarizes that the result of the monitoring of innovation potential of the regions are prerequisites for innovation policy adjustments, make it more dynamic, which ultimately contributes to its effectiveness. So, there are substantial differences in the level of innovation potential of the regions in the Republic of Kazakhstan, meanwhile it is noted that most regions' innovative features and potential can be assessed as average. After analysis of previously used methods, it can be concluded that the ranking of the level of innovation potential of regions takes place in the following order: High level of innovative potential: East Kazakhstan (3 matches), Almaty city (2 matches), Pavlodar (2 matches) and Zhambyl regions (2 matches); Low level of innovative potential: Almaty (2 matches), Mangistau (2 matches), West Kazakhstan (2 matches), Kyzylorda oblast (2 matches). In conclusion, it is emphasized that monitoring of innovative potential of regions creates the preconditions for innovation policy adjustments. These adjustments make the policy more dynamic and contribute to its effectiveness in the long run.

• Journal of Distribution Science
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• v.18 no.8
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• pp.65-74
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• 2020

Purpose: The purpose of study is to examine the effects of design thinking-based programs on creative potential, creativity and innovation behavior, as well as the mediating effect of creative potential and creativity. Research design, data and methodology: The study was conducted through a four-step process. First, the previous studies were investigated. Second, a total of three experts were reviewed to improve and supplement the program. Third, a workshop-based design thinking program was conducted four times. Fourth, the effectiveness of the program was reviewed through data analysis. Results: The design thinking-based program was found to have a statistically positive effect on creative potential, creativity, and innovation behavior. As another hypothesis of this study, by applying the design thinking-based program, it was statistically confirmed that creative potential has a direct, indirect effect, and a mediating effect on innovation behavior. Conclusions: These results provide usability for design thinking in terms of direction for creativity-based creative problem solving and innovation. Finally, design thinking can be used to develop and utilize new services and discover new ideas, especially improve the competitiveness of the company. In addition, it means that the level of innovation action can vary depending on the level of the individual's creative potential.

• Journal of Korea Technology Innovation Society
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• v.7 no.1
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• pp.130-158
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• 2004

This paper aims at renewing the regional innovation system being embossed increasingly as a new paradigm to develop the regional area, using the innovational cluster based on the industrial properties and innovative base in Chungbuk province. As shown in the results of many researches, Chungbuk province is evaluated highly in regional innovation capability and is satisfied with the level of speciality in technical industry so that it has a potential capability to build the regional innovation system. However the clustering competition is growing in intensity between regional groups and there is a possible situation centralized by the high-tech industry into the metropolitan, so building the specialized innovation cluster requires advanced policy decisions and efforts in our won way. Ultimately, for the purpose of structuring the regional innovation system, the specialized innovation cluster reflected in regional industry and capability would be essential. It is time for Chungbuk province to prepare policies in order to make the Chungbuk-type innovation cluster which is neither uniform nor omnipresent.

• International Journal of Computer Science & Network Security
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• v.21 no.6
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• pp.161-168
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• 2021

Within the article, strategic guidelines for the modernization of microeconomic systems are identified. Modernization levels of the potential implementation are formalized for enterprises: contractile, extensive technical, technological, progressive, adaptive, steady, intensive, creative, absolute and leader modernization. This allowed to specify the directions and tasks of the enterprise modernization at different management levels. Accordingly, the conditions and criteria for selecting resource tools are set. It is proved that the strategies of the potential modernization of enterprises must be carried out at four main management levels: first, at the enterprise level; secondly, for a particular type of product / service; third, by functional directions of modernization of separate spheres of the enterprise activity or responsibility, fourth, at the level of structural units of the enterprise. It is substantiated that in the processes due to the activation of the potential modernization, the resources are transformed into the results of the innovation implementation and the investment strategies modernization. A system of tasks for the corporate strategies implementation in order to modernize microeconomic systems has been formed. Key vectors of the activation determine the nature and properties of investment resources and necessary innovations to enhance the modernization potential. Therefore, the system of innovation and investment strategies' modernization, based on the vector and resource provision of the modernization process, is specified:

• Journal of Technology Innovation
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• v.14 no.2
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• pp.67-91
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• 2006

This paper discusses the potential to upgrade the Thai innovation system by university-industry linkages. Our results are structured into three parts. First, the identification of potentials for university-industry linkages (UIL) within the Thai innovation system shows that the re is a wide gap between absorptive capacities of private companies and knowledge production of universities. Second, we present survey results for individual departments at Thai universities showing that UIL are mostly limited to consulting and technical services, hampered by mutual distrust, and maintained to receive an extra personal income. Third, case studies on four typical modes of UIL allow us to discuss various ways to upgrade the Thai IS by UIL in future.

• Journal of Veterinary Science
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• v.22 no.6
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• pp.74.1-74.13
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• 2021

Tissue engineering has been extensively investigated and proffered to be a potential platform for novel tissue regeneration. The utilization of mesenchymal stem cells (MSCs) from various sources has been widely explored and compared. In this regard, MSCs derived from bone marrow have been proposed and described as a promising cell resource due to their high yield of isolated cells with colony-forming potential, self-renewal capacity, MSC surface marker expression, and multi-lineage differentiation capacities in vitro. However, there is evidence for bone marrow MSCs (BM-MSCs) both in vitro and in vivo from different species presenting identical and distinct potential stemness characteristics. In this review, the fundamental knowledge of the growth kinetics and stemness properties of BM-MSCs in different animal species and humans are compared and summarized. Finally, to provide a full perspective, this review will procure results of current information studies focusing on the use of BM-MSCs in clinical practice.

• World Technopolis Review
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• v.1 no.2
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• pp.107-117
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• 2012

As reflected in the title, the main objective of the paper is to explore an appropriate approach to promote technological innovation for developing countries. Aiming to this goal, the paper studies three main innovation system approaches, whose implantation is being attempted in developing countries: first, national innovation systems (NIS), which was developed in OECD countries; second, the system of innovation for development (SID), which is a concept that tries to adapt NIS to developing countries; and third, inclusive innovation which is a pro-poor innovation system. Based on the strengths and the weaknesses of each concept and their potential adaptation in developing countries, the paper proposes an integrated approach of innovation system for developing countries. Compared to developed countries, the concept of innovation system in developing countries should be more complex because it involves not only the formal sector such as enterprises, universities, research institutes, government, and financial system but it also involves NGOs, informal companies, grassroots inventors, local and indigenous knowledge, etc. The last part of the paper discusses the ideas that innovation stakeholders in developing countries can use to promote their proper innovation system.

• Journal of Microbiology and Biotechnology
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• v.34 no.4
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• pp.838-845
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• 2024

Excessive alcohol consumption can have serious negative consequences on health, including addiction, liver damage, and other long-term effects. The causes of hangovers include dehydration, alcohol and alcohol metabolite toxicity, and nutrient deficiency due to absorption disorders. Additionally, alcohol consumption can slow reaction times, making it more difficult to rapidly respond to situations that require quick thinking. Exposure to a large amount of ethanol can also negatively affect a person's righting reflex and balance. In this study, we evaluated the potential of lactic acid bacteria (LAB) to alleviate alcohol-induced effects and behavioral responses. Two LAB strains isolated from kimchi, Levilactobacillus brevis WiKim0168 and Leuconostoc mesenteroides WiKim0172, were selected for their ethanol tolerance and potential to alleviate hangover symptoms. Enzyme activity assays for alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) were then conducted to evaluate the role of these bacteria in alcohol metabolism. Through in vitro and in vivo studies, these strains were assessed for their ability to reduce blood alcohol concentrations and protect against alcohol-induced liver damage. The results indicated that these LAB strains possess significant ethanol tolerance and elevate ADH and ALDH activities. LAB administration remarkably reduced blood alcohol levels in rats after excessive alcohol consumption. Moreover, the LAB strains showed hepatoprotective effects and enhanced behavioral outcomes, highlighting their potential as probiotics for counteracting the adverse effects of alcohol consumption. These findings support the development of functional foods incorporating LAB strains that can mediate behavioral improvements following alcohol intake.

• Fisheries and Aquatic Sciences
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• v.27 no.4
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• pp.256-264
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• 2024

Small pelagic fish populations have long been exploited by various fishing gears in the Natuna Sea, and since the 1970s, purse seine exploitation has expanded to offshore fishing grounds. Various small pelagic fish species are exploited from these waters including spotted sardinella (Amblygaster sirm). This research was conducted for 22 months, from March 2019 to December 2020. The fish sample was taken from the purse seine fleet's catch in the fisheries management area (FMA) 711 Natuna Sea and Karimata Strait, which was brought to Pemangkat fishing port in the West Kalimantan Province, Indonesia. This paper aims to determine the exploitation status of spotted sardinella in the Natuna Sea as a recommendation material for management policies. The methods used in this analysis are estimated age, cohort, population parameters, and spawning potential ratio of spotted sardinella. The results show three primary cohorts of spotted sardinella in the Natuna Sea, with ages ranging from 9 months to 3.1 years and a maximum attainable age (longevity) of 4.3 years. The asymptotic value (L_∞) is 21.79 cmFL in length, with a growth rate (K) of 0.65 per year. The natural mortality rate (M) was 1.19, the total mortality rate (Z) was 2.19, and the fishing mortality rate (F) was 0.99. The exploitation rate (E) was 0.45 and the stock status was still in a sustainable condition. Therefore, the sardinella fisheries can be developed using a precautionary approach and focus on the ecosystem sustainability of FMA 711.

• International Journal of Computer Science & Network Security
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• v.22 no.6
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• pp.400-407
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• 2022

Innovations significantly affect the efficiency of the socioeconomic systems of the regions, acting as a system-forming element of their development. Modern models of economic development also consider innovation activity, intellectual potential, knowledge as the basic factors for stimulating the economic growth of the region. The purpose of the study is to develop methodological foundations for evaluating the effectiveness of a regional innovation system based on a multidimensional analysis of its effects. To further study the effectiveness of RIS, we have used one of the methods of multidimensional statistical analysis - canonical analysis. The next approach allows adding another important requirement to the methodological provision of evaluation of the level of innovation development of industries and regions, namely - the time factor, the formalization of which is realized in autoregressive dynamic economic and mathematical models and can be used in our research. Multidimensional Statistical Analysis for RIS effectiveness estimation was used to model RIS by typological regression. Based on it, multiple regression models were built in groups of regions with low and relatively high innovation potential. To solve the methodological problem of RIS research, we can also use the approach to the system as a "box" with inputs and outputs.