• 한국미생물·생명공학회지
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• 제50권4호
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• pp.533-547
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• 2022

This study investigated the hair growth effect of Schisandra chinensis extract (TS-SC) and TS-SC fermented by Lactobacillus plantarum (TS-SCLF) on human dermal papilla cells (hDPCs). The production of vascular endothelial growth factor (VEGF), insulin-like growth factor 1 (IGF-1), keratinocyte growth factor/fibroblast growth factor 7 (KGF/FGF-7) and hepatocyte growth factor (HGF), transforming growth factor beta 1 (TGF-β1) were examined. The secretion rates of VEGF and KGF/FGF-7 were high in TS-SC, and the secretion rates of IGF-1 and HGF were high in TS-SCLF. TGF-β1 was inhibited in a concentration-dependent manner in all samples. Gene expression of VEGF, IGF-1, KGF, HGF and alkaline phosphatase, relevant to hair growth, were examined. The data revealed that TS-SC and TS-SCLF successfully promoted hair growth in hDPCs. The IGF-1 gene was expressed in a dose-dependent manner in TS-SCLF. These results indicate that TS-SC and TS-SCLF fermented extract effectively promoted hair growth and gene expression relevant to hair growth in hDPCs. Used in clinical trials the test substance 'CMK-LPF01' showed a statistically significant increase in the number of hairs at 8 weeks, 16 weeks, and 24 weeks compared to before product use, and a change in hair growth, a secondary efficacy evaluation variable. Through additional research in the future, it is expected that "CMK-LPF01" can be developed as a functional material that can help alleviate symptoms of hair loss.

• STI Policy Review
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• 제7권1호
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• pp.1-16
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• 2016

Technology supply has been the main thrust of the Korean government's science & technology policy, focusing on the development and acquisition of new technology in line with the catching-up strategy of economic growth and industrial development. However, new social or societal problems have become major government policy issues, heralding new innovation policy aimed to address them. Such new policy initiatives for social problem-solving present a niche where the existing system of government innovation policy process is challenged, including such processes as goal-setting, planning, implementation, project management, and evaluation. The rigidity of the existing institution of government innovation policy, however, still shapes the content and progression of innovation policy for social problem-solving. This study reviews Korean innovation policy for social problem-solving as a policy niche, and aims to clarify its challenges and opportunities. It uses a system transition framework to explain the emergence and evolution of the innovation policy niche in Korea. The main research question is to what extent and in what aspect the existing innovation policy regime shaped innovation policy for social problem-solving. The study examines the inertia of the current paradigm of innovation policies and R&D programs, and sheds light on the search for a distinctive identity for innovation policies that tackles social problems.

• 디지털산업정보학회논문지
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• 제9권2호
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• pp.151-163
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• 2013

It goes without saying that the technology innovation plays an important role in the sustainable growth of the firm in the global economy. It, however, is not easy to fulfill this simple and obvious fact. Because there are a lot of barriers hindering innovation activities of firms and innovations are interrupted or don't even attempts by this barriers. So in this paper, I study barriers of firms that try to innovation and how much negative impact exist on firm's innovation performance by that. And also I try to find influence on firm's performance because of declined innovation activities. To prove this, KIS(Korean Innovation Survey) 2008, which was surveyed by STEPI(Science and Technology Policy Institute), is used to find relationships among variables; innovation barriers, innovation activities and firm's performance. In the result, I find that financial barrier influence negatively to the process innovation with small business, capable barrier influence negatively to the process innovation with large business and organizational barrier influence negatively to the process innovation with both small and large business. And, it also appear that organizational barrier has not moderating effect but process efficiency has moderating effect significantly with small business that have more positive effect.

• 대한안전경영과학회지
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• 제21권3호
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• pp.1-9
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• 2019

The Industrial Innovation Movement, based on win-win cooperation with SMEs, is a structure that enables suppliers who have struggled with corporate growth through productivity innovation due to poor manufacturing environment and lack of innovation. To this end, consultants and technical experts will support production innovation activities to improve production methods and improve productivity through process and management consulting. The purpose of this study was to explore the driving factors of the industrial innovation movement to improve the corporate ecosystem by improving the productivity of SMEs using modified IPA. The research results are as follows. First, in order to revitalize the Industrial Innovation Movement, the CEO-related elements of the participating companies should be maintained and strengthened. The motivation, education support, innovation organizational culture, the establishment of an innovation promotion system requires centralization of efforts for improvement. Second, in order to revitalize the Industrial Innovation Movement, the consultant's ability to analyze problems and suggest alternatives should be continuously strengthened. Third, in terms of the Central Promotion Headquarters, it was found that the Industrial Innovation Movement would be successful if the public information, industrial inspection for benchmarking, and provision of various information to support innovation activities were urgently improved.

• 기술혁신학회지
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• 제6권3호
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• pp.328-344
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• 2003

This paper is aimed at analyzing the effect of Information Technology (IT) investment on the output growth and Total Factor Productivity (TFP) of Korean stock industry. Data on 24 stock firms for the eleven years (1991-2001) are used for the analysis. It is identified that there are both direct and indirect impacts of IT investment of the Korean stock industry on output growth. The total effect on output growth is 1.34 percentage point per year, which divided into a direct effect of investment in IT on the output growth is 1.97 and an indirect effect on the TFP is -0.63 percentage points per year. Results show that IT investment cannot contribute to increased stock industry productivity. Therefore, the Korean stock industry has not benefited from increased investment on IT in increasing productivity, implying the so-called productivity paradox has existed during the period.

• 한국기술혁신학회:학술대회논문집
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• 한국기술혁신학회 2000년도 추계 학술대회(The 2000 Autumn Conference of korea Technology Inovation Society)(한국기술혁신학회)
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• pp.346-356
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• 2000

This paper aims to analyse the relationship between R＆D investment and economic growth in Korea. The analysis result shows 38 percent of average economic growth rate(7.1%) of Korea between 1976 and 1998 was achieved by the growth of Total Factor Productivity (TFP), and the R&D investment during the period contributed in achieving the economic growth rate by as much as 9.86 percent. In the process of the estimate, the rate of return of the R&D investment from both government and private was calculated as 47 percent. The relationship between private R&D investment, government R&D investment and the GDP was also investigated, and it was estimated that the private sector invested 2.0 percent of the GDP in R&D during the period, and was found that 1 won of government R&D investment induced 0.202 won of private sector's R&D investment. However, the time-lag effect, which is naturally believed to exist between the R&D investment and the economic growth, could not be analysed in a mathematical form, because of the lack of the data to establish this relationship. However, this paper believe that the time-lag effect in this relationship was included implicitly by using the data of 23 years.

• 한국기술혁신학회:학술대회논문집
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• 한국기술혁신학회 2001년도 춘계학술대회:발표자료
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• pp.141-158
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• 2001

This paper examines the causality issue between telecommunications investment and economic growth for South Korea by applying recently developed time series techniques. Tests for unit roots, co-integration, and Granger causality are presented. The results show that hi-directional causality runs from telecommunications investment to economic growth for South Korea. This means that increased telecommunications investment directly affects economic growth and an increase in real income also influences telecommunications investment. The study also discusses the implications of the results for addressing telecommunications policy in South Korea.

• 기술혁신연구
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• 제12권1호
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• pp.49-65
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• 2004

This study investigates the effect of technology outsourcing on the value of the firm in Korea. The result shows that the technology outsourcing in the high growth industries gives positive effects on the value of the firm. The results supports the investment opportunity hypothesis. With respect to the free cash flow hypothesis, this study finds no supporting evidences. The paper concludes that growth is the dominant factor for determining the effect of technology outsourcing on the value of the firm.

• 기술혁신학회지
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• 제6권2호
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• pp.203-212
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• 2003

본 논문은 연구개발 및 정보통신스톡의 투입이 국내 산업의 생산성을 단순히 양적인 측면에서 증가를 유도하였는지 아니면 총요소생산성의의 증가를 통한 질적인 향상을 유도하였는지의 차이를 성장회계분석과 시계열분석을 통하여 차이를 규명하고 있다. 양적인 측면에서 투입요소들에 대한 영향정도는 유효하게 나타나고 있는 반면, 질적인 측면에서의 투입요소들의 유효성은 모호한 결과를 보이고 있다.

• 한국광학회:학술대회논문집
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• 한국광학회 2008년도 하계학술발표회 논문집
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• pp.71-72
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• 2008

We review and report our analytical results in the technology front of optical industry in Japan as optical $recording^{1)}$, semiconductor $stepper^{2)}$, fiber communication, digital $camera^{4)}$ and $OCT^{5)}$ which are contributing to the improvement of people's higher quality of life and to the industrial economical growth from the aspects of the University, Industry and Government collaborations including international comparison to enhance the progress of sustainable global photonic innovation eco-systems. In the following part, some statistics of remarkable economical growth in east Asia and the global warming issue will be mentioned.