• 동의생리병리학회지
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• 제23권3호
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• pp.734-739
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• 2009

Benign paroxysmal positional vertigo(BPPV) is the most common peripheral vestibular disorder clinically. It causes dizziness or vertigo, lightheadedness, imbalance, and nausea. by a change of position of the head with respect to gravity. BPPV is very well explained by mechanical consequences of loose debris within the inner ear and oriental medical theory of vertigo resulting from Phlegm(痰). Therefore, for treatment of BPPV, we can consider not only oriental medical therapy but also Canalith Repositioning Procedure. We report four improved cases of dizziness patient diagnosed BPPV and Dam Hun(痰暈) treated by canalith repositioning procedure and herbal medication and acupuncture.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2002년도 추계학술대회 논문집(I)
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• pp.182-187
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• 2002

Since most of main noise sources of the railroad vehicle are transmitted to the passenger's ear through the vibration of the panel, the insulation performance of the panels should be high enough to protect the passengers from the noisy environment. Specifically, the composite materials which are generally used for reducing the weight of the vehicle compartment have the low insulation performance, noise control actions should be taken appropriately by considering the insulation performance of the panels. In this study, the insulation performances of the inner/outer panels were evaluated and the contribution of the aluminum door was estimated compared to the composite panels. The results can furnish an indepth understanding of the insulation characteristics of the panel of railroad vehicle.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2001년도 전력전자학술대회 논문집
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• pp.377-380
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• 2001

The vestibular system located in the inner ear controls reflex body posture and movement. It has the semicircular canals sensing an angular acceleration and the otolith organs sensing a linear acceleration. With this organic signal, medical doctor decide if a person has disease or not. To obtain this data, a precision stimular system is considered. Robust control is needed to obtain eye signals induced by off-vertical axis rotation because of an unbalanced load produced by tilting the axis of the system upto 30 degrees. In this study, off-vertical axis rotatory system with visual stimulation system are developed. This system is consisted of head mounted display for generating horizontal, vertical, and three dimensional stimulus patterns. Furthermore wireless recording system using RF modem is considered for noiseless data transmission.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1976년도 제10차 학술대회연제 순서 및 초록
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• pp.86.1-86
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• 1976

Meniere씨 병은 1861년 Prosper Meniere에 의하여 처음으로 내이에 관한 임상증후군으로써 기술되었으며, 이후 그의 이름으로 명명되었다. 최근 저자는 2례에서 Meniere's씨 병으로 진단한 뒤 내과적 요법으로 치료하였으나 실패하여, 수술적 요법으로써 1례에서는 Cawthorne's horizontal canal labyrinthectomy를 1례에서는 endolymphatic sac decompression을 시행하여 만족할 만한 결과를 얻었기에 문헌적 고찰과 함께 보고하는 바이다.

• 한방안이비인후피부과학회지
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• 제16권1호
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• pp.214-219
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• 2003

Vertigo is one of the common symptoms that we can see often clinically. It is hallucination to motion of oneself or surroundings. Vertigo include not only simple whirling sensation but also leaning or falling down sensation. Particularly in benign paroxysmal positional vertigo(BPPV), the principal symptom is dizziness and accompanied by nausea, lightheadness, vomiting. They are induced by positional change which like shake ones head or lay down or turn over in one' s sleep. Cause of BPPV is otoconium fragments which are released from inner ear and stimulate ampulla of semicircular canal. So in treatment BPPV, we often using the Dix-hallpike maneuver that realignment otoconium fragments. A case of vertigo patient suggested BPPV who is diagnosed oriental medically as weakly dizziness showed prominent improvement by medicate Bojungikgi-tang and operate otoconium-realignmentation (improved Dix-hallpike maneuver) maneuver so we reported.

• 한국동물번식학회:학술대회논문집
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• 한국동물번식학회 2001년도 춘계학술발표대회
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• pp.48-48
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• 2001

A new neurological mutant has been found in the ICR outbred strain mouse. Affected mice display profound deafness and a head-tossing and bidirectional circling behavior, showing an autosomal recessive mode of inheritance. It was, therefore, named cir/Kr with the gene symbol cir. The auditory tests identified clearly the hearing loss of the cir mice when compared to wild type mice. Pathological studies confirmed the developmental defects in the middle ear, cochlea, cochlear nerve, and semicircular canal areas, which were correlated to the abnormal behavior observed in the cir mice. Thus, cir mice may be useful as a model for studying inner ear abnormalities and deafness. We have constructed a genetic linkage map by positioning 14 microsatellite markers across the (cir) region and intraspecific backcross between cir and C57BL/6J mice. The cir mouse harbors an autosomal recessive mutation on mouse chromosome 9. The cir gene was mapped to a region between D9Mit116 and D9Mit38 Estimated distances between cir and D9Mit116, and between cir and D9Mit38 are 0.7 and 0.2 cM, respectively. The gene in order was defines : centromere-D9Mit182-D9Mit51/D9Mit79/D9Mit310-D9Mit212/D9Mit184-D9Mit116-cir-D9Mit38-D9Mit20-D9Mit243-D9Mit16-D9Mit55/D9Mit125-D9Mit281. The mouse map location of the cir locus appears to be in a region homologous to human 3q21. Our present date suggest that the nearest flanking marker D9Mit38 provides a useful anchor for the isolation of the cir gene in a yeast artificial chromosome contig.

• Journal of Ginseng Research
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• 제33권2호
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• pp.155-159
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• 2009

Sudden idiopathic sensorineural hearing loss is a disease that develops within several hours to several days. Its etiology has not yet been verified, but the disturbance of the circulation of blood in the inner ear, inner-ear hydrops, and viral infection are considered possible causes of the disease. This study was conducted to evaluate the effect of Panax ginseng extract, which is known to have a vasodilatory effect, on sudden sensorineural hearing loss. Sixty-nine patients suffering from sudden sensorineural hearing loss were admitted to Korea University Anam Hospital from March to December 2008. They were divided into the experimental (30 ears) and control (39 ears) groups. Ginseng extract (2700 mg/day, 4 weeks) was added to the therapeutic regimen in the experimental group. The effect of ginseng extract therapy was analyzed according to the factors relating to the prognosis. A considerable hearing improvement was documented in both groups (32.2 dB in the experimental group and 25.8 dB in the control group). However, there was little beneficial effect of ginseng extract on additional hearing improvement compared with control. The total recovery rate of the experimental group (80.0%) was better than that of the control group (58.9%), and the experimental group's high-tone hearing gain at 3 kHz (29.7 dB) was better than that of the control group (21.7 dB). The results of the study suggest that the effects of ginseng therapy tend to be superior to those of the conventional therapy, but the difference between the two is not statistically significant. The hearing gains tend to be in the higher frequencies and may be due to the promotion of cellular differentiation from the supporting cells.

• The Korean Journal of Physiology and Pharmacology
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• 제17권6호
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• pp.537-546
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• 2013

Deiters' cells are the supporting cells in organ of Corti and are suggested to play an important role in biochemical and mechanical modulation of outer hair cells. We successfully isolated functionally different $K^+$ currents from Deiters' cells of guinea pig using whole cell patch clamp technique. With high $K^+$ pipette solution, depolarizing step pulses activated strongly outward rectifying currents which were dose-dependently blocked by clofilium, a class III anti-arrhythmic $K^+$ channel blocker. The remaining outward current was transient in time course whereas the clofilium-sensitive outward current showed slow inactivation and delayed rectification. Addition of 5 mM tetraethylammonium (TEA) further blocked the remaining current leaving a very fast inactivating transient outward current. Therefore, at least three different types of $K^+$ current were identified in Deiters' cells, such as fast activating and fast inactivating current, fast activating slow inactivating current, and very fast inactivating transient outward current. Physiological role of them needs to be established.

• Journal of Genetic Medicine
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• 제6권1호
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• pp.8-24
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• 2009

난청의 약 50%는 유전적 요소가 원인이기 때문에 난청의 유전적 배경을 이해하는 것은 중요하다. 현재까지 150개 이상의 원인유전자들이 밝혀져 있다. 이번 종설에서는 유전성 난청의 분류, 유전성 난청 원인규명의 난점, 유전성 난청과 관련된 내이의 구조와 기능, 증후군성난청, 비증후군성난청, 미토콘드리아 유전성 난청, 그리고 다인자성 난청에 관해 논하고자 한다. 그리고 유전성 난청을 가진 환자의 치료적 접근과 유전적 상담을 간략하게 설명하고, 마지막으로 유전성 난청에 대한 앞으로의 연구 방향을 제시하고자 한다.

• 대한한방소아과학회지
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• 제13권2호
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• pp.171-186
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• 1999

Atopic dermatitis is a chronic or chronically relapsing, pruritic dermatitis. It commonly occurs in patients with a personal or family history of atopy. We studied 67 children suffering from atopic dermatitis Oriental Medicine Hospital in Kyunghee University, and analyzed sex, age, feeding, clinical manifestation, risk factor. The results were as follows : 1.Most age distribution of children was from 2 to 6, male to female ratio was 1:1.03 2.Breast-feeding to milk-feeding ratio was 2.93:1 3.Frequency of aggravating symptom by specific food was 31.3%, among this, meat(especially chicken) was revealed high risk factor 4.Frequency of family history suffering from other allergic disease was 61.2%, among this father to mother ratio was 1.27:1 5.Sites of atopic dermatitis were as follows : The inner space of elbow and knee joint was 77.65, back, face, neck was 56.7%, back of ear was 52.2%, wrist was 46.3%, abdomen was 38.8%, ankle was 34.3%,head was 29.9%.