• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3821-3824
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• 2012

Aim: SNPs of ERCC1 and ERCC2 genes have been found to be associated with response to platinum therapy in different clinical settings. In the current study, we investigated the relationship of SNPs in ERCC1 and ERCC2 to cisplain response and survival in osteosarcoma patients. Methods: 267 consecutive patients diagnosed with osteosarcoma between January 2003 to January 2005 were followed up until the end of January 2010. ERCC1 Asn118Asn, ERCC1 Gln504Lys, ERCC2 Asp312Asn and ERCC2 Lys751Gln polymorphisms were detected based upon the Sequenom MassARRAY platform.Results: For ERCC1 Asn118Asn, the variant genotype T/T was strongly significantly associated with a higher event free survival when compared with the wild-type C/C, with an adjusted OR (95% CI) of 0.39 (0.14-0.95). ERCC2 751 A/A genotype showed increased event free survival of osteosarcoma (HR=0.44; 95%CI=0.10-0.87). However, we did not find significant association of ERCC1 Gln504Lys and ERCC2 Asp312Asn polymorphisms with prognosis of osteosarcoma. Conclusions: We first report associations of four SNPs, ERCC1 Asn118Asn, ERCC1 Gln504Lys, ERCC2 Asp312Asn and ERCC2 Lys751Gln, with risk of death from osteosarcoma in a Chinese population, indicating ERCC1 118T/T and ERCC2 A/A may be used as surrogate markers for clinical outcome of osteosarcoma treatmetn with cisplain.

• Journal of Korea Port Economic Association
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• v.23 no.4
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• pp.1-22
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• 2007

The present study examined the effects of the factors of port service quality on customer satisfaction and surveyed customers' perception on service quality and their satisfaction with port services by comparing Incheon Port with Qingdo Port, Tianjin Port and Dalian Port. According to the results, the quality of port services can be divided into three levels-inner quality, external environment quality and interaction quality, and except the external environment quality of the Dalian Port, the three levels of service quality were found to have significant effects on customer satisfaction. In addition, according to the results of comparing customers' perception on the three levels of service quality among the ports, the Incheon Port was inferior to the Qingdo Port, the Tianjin Port and the Dalian Port in inner quality, and to the Qingdo Port and the Tianjin Port in external environment quality, but superior to the Tianjin Port and the Dalian Port in interaction quality. However, customers' satisfaction with the Incheon Port was lower than that with the Qingdo Port and the Tianjin Port.

• Journal of architectural history
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• v.14 no.1 s.41
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• pp.135-150
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• 2005

Historical study of Korean traditional houses have been carried, mainly, based on the geographical region of Korean peninsula. However, the case of primitive houses can not be researched according to the geographical and racial concept of modern nations. This study aims to examine the primitive houses of ethnic minorities of northeastern China, where the cultural and racial background have been deeply rooted in the history of Korea as well as Korean traditional houses. Through the field research and literary materials, the basic types of primitive houses of the five ethnic minorities could be identified. Among these types, those that have possible relationship with Korean houses, are cone shaped house, underground house, and elevated wooden house. Archeological evidences of underground houses were amply found in Korea already, but above ground evidences could not be found. However, It seems quite certain that the cone shaped houses and elevated wooden houses, too, existed in Korea as one of the earliest housing types, as can be examined in remaining examples in Korean peninsula. With no doubt, the primitive houses of Korea have strong connection with that of the ethnic minorities of northeastern China. This can be verified through the facts that the evidences of cone shaped houses, the similarities of the use of Inner space, the evidences of elevated wooden houses. Also, the combination of wooden floor and ondol, which is known to be one of the strongest characteristic of Korean traditional houses, could be originated from the combination of primitive summer house, the elevated wooden house, and the winter house, the underground house with ondol.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.43 no.10
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• pp.875-887
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• 2015

The optimal layout design is used in the development of various areas of industry. In the field of space systems, components must be placed properly in the limited space of spacecraft by considering mechanical, thermal and electrical interfaces. When applying optimal layout design, a proper, even ideal placement of components is possible in the limited space of a satellite platform. Through the optimal placement design, the minimized moment of inertia enhances efficient attitude control, rapid maneuver and mission performance of the satellite. This paper proposes 3D optimal layout design that minimizes the spacecraft's moment of inertia and effect of thermal dissipation between inner components as well as interference between inner components based on a cubic-structure satellite platform. This study proposes the new genetic algorithm for 3D optimal layout design of the satellite platform.

• The korean journal of orthodontics
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• v.40 no.3
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• pp.195-206
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• 2010

The aim of this report is to present an intraoral upper molar distalization system supported with zygomatic anchorage plates (Zygoma-gear Appliance, ZGA). This system was used for a 16-year-old female patient with a Class II molar relationship requiring molar distalization. The system consisted of bilateral zygomatic anchorage plates, an inner-bow and heavy intraoral elastics. Distalization of the upper molars was achieved in 3 months and the treatment results were evaluated from lateral cephalometric radiographs. According to the results of the cephalometric analysis, the maxillary first molars showed a distalization of 4 mm, associated with a distal axial inclination of $4.5^{\circ}$. The results of this study show that an effective upper molar distalization without anchorage loss can be achieved in a short time using the ZGA. We suggest that this new system may be used in cases requiring molar distalization in place of extraoral appliances.

• International Journal of Industrial Entomology and Biomaterials
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• v.9 no.2
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• pp.273-277
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• 2004

Variation in the size of the silk filament will determine the uniformity and quality of the silk reeled. In the present study, an attempt has been made to study the filament size variation in 6 multivoltine parental breeds and 9 multivoltine ${\times}$ bivoltine hybrids in all three seasons of a year. All multivoltine breeds and multivoltine ${\times}$ bivoltine hybrids showed variation in filament size throughout its length from the outer layer to inner layer. Results of the present study indicated that the size of the filament decreased from outer to inner layer. The decrease in filament size was sudden in some breeds/hybrids whereas it was gradual in other. Relationship between filament length to that of slope, average filament size to slope, and maximum filament size to slope was determined based on regression analysis. Regression analysis revealed significant positive correlation between slope vs average filament length (r=0.92$^{**}$) in multivoltine${\times}$bivoltine hybrids. Among parental breeds, 96C showed lowest slope of the curve (b-value: -0.00428) and 96A showed highest slope of the curve (b-value: -0.00269). Among 9 hybrids, PM${\times}$N $B_4$ $D_2$ recorded lowest slope value (b-value: -0.00328) and BL24${\times}$N $B_4$ $D_2$ showed highest value for slope of the curve (b-value: -0.00234). The breed 96C, which showed lowest slope value can be utilized for future breeding programmes to breed strains with less size deviation. Three multivoltine${\times}$bivoltine hybrids viz., PM${\times}$N $B_4$ $D_2$, 96E${\times}$CSR19 and BL67${\times}$CS $R_{101}$ , which showed less slope values (b-values: -0.00328, -0.00300 and -0.00297 respectively) can be utilized for commercial exploitation to produce uniform silk.k.

• Nano
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• v.13 no.12
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• pp.1850147.1-1850147.14
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• 2018

In this work, water-soluble and blue-emitting carbon nanodots (CDs) were synthesized from apple peels for the first time via one-step hydrothermal method. The synthetic route is facile, green, economical and viable. The as-prepared CDs were characterized thoroughly by transmission electron microscopy (TEM), X-ray diffraction (XRD), Raman, Fourier transform infrared (FT-IR), X-ray photoelectron (XPS), fluorescence and UV-Vis absorption spectroscopy in terms of their morphology, surface functional groups and optical properties. The results show that these CDs possessed ultrasmall size, good dispersivity, and high tolerance to pH, ionic strength and continuous UV irradiation. Significantly, the CDs had fast and reversible response towards temperature, and the accurate linear relationship between fluorescence intensity and temperature was used to design a novel nanothermometer in a broad temperature range from 5 to $65^{\circ}C$ facilely. In addition, the fluorescence intensity of CDs was observed to be quenched immediately by Cr(VI) ions based on the inner filter effect. A low-cost Cr(VI) ions sensor was proposed employing CDs as fluorescent probe, and it displayed a wide linear range from 0.5 to $200{\mu}M$ with a detection limit of $0.73{\mu}M$. The practicability of the developed Cr(VI) sensor for real water sample assay was also validated with satisfactory recoveries.

• Journal of Creative Information Culture
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• v.7 no.1
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• pp.31-41
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• 2021

This study aimed to investigate the status of happiness according to the background of teachers, and to find out the effects of social support and job satisfaction on teachers' happiness. For this, the data of 249 teachers participating in the teacher training were analyzed using the Google online survey. As a result, there was no significant difference in gender or career, but elementary school teachers were found to have higher happiness than high school teachers. All the sub-factors of social support and job satisfaction were found to have positive relationship with the happiness sub-factors. In addition, in terms of the effects of social support and job satisfaction on inner happiness, teaching consciousness, autonomy, and trustworthy alliance had a positive effect on inner happiness, and the trustworthy alliance, advice, teaching consciousness on external commitment, and social belonging, Autonomy, development, and innovation had a positive effect on self-regulated happiness. It is believed that there is a need to improve the happiness of teachers using the results of this study.

• Geomechanics and Engineering
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• v.29 no.4
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• pp.377-390
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• 2022

The stability of the roof rock-coal pillar-floor rock composite structure is of great significance to coal mine safety production. The cracks existing in the composite structure seriously affect the stability of the roof rock-coal pillar-floor rock composite structure. The numerical simulation tests of rock-coal-rock composite structures with different crack characteristics were carried out to reveal the composite structures' mechanical properties and failure mechanisms. The test results show that the rock-coal-rock composite structure's peak stress and elastic modulus are directly proportional to the crack angle and inversely proportional to the crack length. The smaller the crack angle, the more branch cracks produced near the main control crack in the rock-coal-rock composite structure, and the larger the angle between the main control crack and the crack. The smaller the crack length, the larger the width of the crack zone. The impact energy index of the rock-coal-rock composite structure decreases first and then increases with the increase of crack length and increases with the increase of crack angle. The functional relationships between the different crack characteristics, peak stress, and impact energy index are determined based on the sensitivity analysis. The determination of the functional relationship can fully grasp the influence of the crack angle and the crack length on the peak stress and impact energy index of the coal-rock composite structure. The research results can provide a theoretical basis and guidance for preventing the instability and failure of the coal pillar-roof composite structure.

• Cartoon and Animation Studies
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• s.49
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• pp.113-142
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• 2017

Mamoru Hosoda's (2015) depicts the adventure with which a physically and psychologically isolated boy is growing through a 'Relationship' with surrounding beings. This paper intends to reveal the essence of 'Relationships' and 'True Growth' that the director presents to us. In the film, a boy's adventure is centered on two worlds (the human world and the beast world). Here, the human world refers to a civilized society, and the beast world 'Naturalness' as the inner nature of a human being. The human world and the beast world in the mirror-relationship with the human world were originally a world, and the inside and the outside of the place for all existing things were connected in one. Human beings were never superior to the surrounding beings, but all beings were equal in relationship. The way of thinking in that age is called 'Symmetrical Thinking.' But as human beings opened the road to self-centered civilization, they eliminated 'Nature' inside themselves. As a result, the two worlds (human beings and nature, or the human world and the beast world) were eventually separated. This destroyed not only the human-nature relationship but also the human-to-human relationship, which is one of the characteristics of the civilized society where we currently live. Through the boy's question, "Who am I?", the director suggests to us that the inner nature of a human being as a natural being should be reinstated. This means that a human being restores the "relationship" with all beings (other beings) surrounding himself or herself, which is the only alternative to overcome various violences of the civilized society that we have created. The full growth of a human being is achieved at this point. In this way, offers a reflection on the human civilization and society, and questions the possibility of coexistence with other beings, through cosmic thinking (symmetrical thinking) that we have lost. In this respect, it is a text presented as a 'Model of Maturity' for an immature human society.