• Title/Summary/Keyword: Injection stage

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The Efficacy of Intra-Articular Hyaluronic Acid Injections in Ankle Osteoarthritis (족관절 골관절염에서의 관절 내 Hyaluronic Acid 주사의 유용성)

  • Park, Chul Hyun;Park, Jeong Jin;Seok, Hyun Gyu;Woo, In Ha
    • Journal of Korean Foot and Ankle Society
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    • v.26 no.2
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    • pp.71-77
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    • 2022
  • Purpose: This study sought to investigate the appropriate indications for intra-articular injection of hyaluronic acid in ankle osteoarthritis, its efficacy at each stage of osteoarthritis and to compare the efficacy related differences at each stage. Materials and Methods: A retrospective study was conducted from January 2016 to September 2019 on 43 patients (50 cases) diagnosed with ankle arthritis and given intra-articular injection of hyaluronic acid. Patients were classified according to the modified Takakura ankle osteoarthritis stages. Stage 2 comprised 24 cases; stage 3A, 15 cases; stage 3B, 8 cases; and stage 4, 3 cases. The clinical evaluation was carried out using the visual analogue scale (VAS), American Orthopaedic Foot and Ankle Society (AOFAS) score, and the Foot and Ankle Outcome Score (FAOS). The patients' satisfaction with the injection was evaluated at 1 year after injection. A radiographic evaluation was performed to gauge the progression of osteoarthritis before and after the injection. Results: The VAS, AOFAS score, and FAOS at 3 months and 1 year after injection showed statistically significant improvements compared to those before the injection. There was a significant difference in the VAS for each stage over time; however, this was not the case with the AOFAS score and the FAOS. A significant improvement of the VAS after injection was seen only in stage 3A when compared with the other stages. The overall satisfaction rate with the injection was 90%. There were no ankle osteoarthritic stage changes in the serial follow-up radiograph. Conclusion: Intra-articular injection of hyaluronic acid resulted in a significant clinical improvement up to 1 year after the injection. Therefore, the intra-articular injection of hyaluronic acid could be a treatment option for ankle osteoarthritis.

Effects of Gas Injection on the Heating Performance of a Two-Stage Heat Pump Using a Twin Rotary Compressor with Refrigerant Charge Amount

  • Heo, Jae-Hyeok;Jeong, Min-Woo;Jeon, Jong-Ug;Kim, Yong-Chan
    • International Journal of Air-Conditioning and Refrigeration
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    • v.16 no.3
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    • pp.77-82
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    • 2008
  • For heat pumps used in a cold region, it is very important to obtain appropriate heating capacity. Several studies using a variable speed compressor and an additional heater have been performed to enhance heating capacity at low ambient temperatures. However, for outdoor temperature conditions below $-15^{\circ}C$, it is still difficult to obtain enough heating capacity above the rated value. In recent studies, the application of gas injection technique into a two-stage heat pump yielded noticeable heating performance improvement at low temperature conditions. In this study, the heating performance of a two-stage gas injection heat pump with a rated capacity of 3.5 kW was measured and analyzed by varying refrigerant charge amount and EEV opening at the standard heating condition. The heating performance of the two-stage gas injection heat pump was compared with that of a two-stage non-injection heat pump. The heating capacity and COP of the two-stage gas injection heat pump were improved by 2-10% at the optimal charging condition over those of the two-stage non-injection heat pump.

Effects of Vapor Injection on a Compressor in a Transcritical CO2 Cycle (초임계 CO2 사이클에서 가스 인젝션이 압축기 성능에 미치는 영향)

  • Kim, Woo-Young;Shim, Jae-Hwi;Lee, Yong-Ho;Kim, Hyun-Jin
    • The KSFM Journal of Fluid Machinery
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    • v.10 no.2 s.41
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    • pp.16-21
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    • 2007
  • Potential advantages of using vapor injection in a two stage rotary compressor for a $CO_2$ heat pump water heater system were addressed in this paper by numerical simulation. Vapor separated from a flash tank in the middle of the expansion process can be used for injection into the second stage suction plenum of the compressor to improve the system performance. Vapor injection increases the intermediate pressure between the two stages, thus increasing the first stage compressor work and reducing that of the second stage. As a whole, however, the compressor input power increases due to injected mass flow rate for the second stage. Computer simulation showed that increment of the cooling capacity by vapor injection exceeded that of the compressor work, thus improving the system performance. COP improvement by vapor injection was calculated to be about 5-14% for normal operating conditions. With vapor injection, a maximum COP was found when the displacement volume of the second stage becomes 90-95% of that of the first stage of the compressor.

A Study on the Diesel DI-HCCI Combustion Characteristics using 2-stage Injection Method (2단 분사 방식을 적용한 디젤 DI-HCCI 연소특성에 관한 연구)

  • Chung, Jae-Woo;Kang, Jung-Ho;Kim, Byoung-Soo;Kang, Woo;Kim, Hyun-Chul
    • Transactions of the Korean Society of Automotive Engineers
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    • v.12 no.6
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    • pp.66-73
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    • 2004
  • In this study, combustion characteristics and various performances of a Diesel fuel DI-HCCI engine using 2-stage injection method were investigated. From these researches, application ability of 2-stage injection strategy to a DI-HCCI engine was confirmed and improvement methods of performances were considered. As the results, Using 2-stage injection method, without change of engine specifications and loss of IMEP, exhaust of NOx and Smoke emissions could be reduced to about 1/3 (at 1400rpm, IMEP 6bar) compared to conventional Diesel combustion.

Numerical Study on the Effect of Diesel Injection Parameters on Combustion and Emission Characteristics in RCCI Engine (RCCI 엔진의 디젤 분사 파라미터에 따른 연소 및 배출가스 특성에 대한 수치적 연구)

  • Ham, Yun-Young;Min, Sunki
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.6
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    • pp.75-82
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    • 2021
  • Low-temperature combustion (LTC) strategies, such as HCCI (Homogeneous Charge Compression Ignition), PCCI (Premixed Charge Compression Ignition), and RCCI (Reactivity Controlled Compression Ignition), have been developed to effectively reduce NOx and PM while increasing the thermal efficiency of diesel engines. Through numerical analysis, this study examined the effects of the injection timing and two-stage injection ratio of diesel fuel, a highly reactive fuel, on the performance and exhaust gas of RCCI engines using gasoline as the low reactive fuel and diesel as the highly reactive fuel. In the case of two-stage injection, combustion slows down if the first injection timing is too advanced. The combustion temperature decreases, resulting in lower combustion performance and an increase in HC and CO. The injection timing of approximately -60°ATDC is considered the optimal injection timing considering the combustion performance, exhaust gas, and maximum pressure rise rate. When the second injection timing was changed during the two-stage injection, considering the combustion performance, exhaust gas, and the maximum pressure increase rate, it was judged to be optimal around -30°ATDC. In the case of two-stage injection, the optimal result was obtained when the first injection amount was set to approximately 60%. Finally, a two-stage injection rather than a single injection was considered more effective on the combustion performance and exhaust gas.

Effects of Multi-stage Pilot Split Injection Strategy on Combustion and Emission Characteristics in a Single-Cylinder Diesel Engine (단기통 디젤엔진에서 다단 파일럿 분할 분사 전략이 연소 및 배기가스 특성에 미치는 영향)

  • Lee, Hyungmin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.7
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    • pp.692-698
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    • 2020
  • This paper examines the effects of a multi-stage pilot split injection strategy on combustion and exhaust emission factors in a single-cylinder diesel engine. One analysis noted that in the single-injection condition, the maximum in-cylinder pressure and rate of heat release were highest. The pilot injection quantity was evenly divided, showing a tendency to decrease as the number of injections increased. In another injection condition, when the multi-stage pilot split injection strategy was applied, IMEP, engine torque, and combustion increased. The COVIMEP was greatest with the lowest combustion efficiency. The combustion ability was poor. In a single injection condition, the O2 concentration in the exhaust gas was the lowest and the CO2 was the highest. When the multi-stage split injection strategy was applied, the low temperature combustion process proceeded, and the oxidation rate of CO2 decreased while the emission level increased. In a single injection condition in which a locally rich mixture was formed, the HC emission level showed the highest results. A 55.6% reduction of NOx emission occurred under a three-stage pilot injection condition while conducting a multi-stage pilot split injection strategy.

A Fundamental Study on The Expression of Initial Strength of Injection Materials for Steel Pipe Multi-Stage Method using Circulating Resources (순환자원을 활용한 강관다단공법용 주입재의 초기강도 발현에 대한 기초연구)

  • Sang-Huwon Song
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.5
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    • pp.557-562
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    • 2023
  • This study reviewed the use of soil injection materials using circulating resources as injection materials for the steel pipe multi-stage construction method. The tests performed were homogel time and homogel compressive strength. The steel pipe multi-stage construction method is an auxiliary construction method for tunnels, and the expression of initial strength after construction is an important factor. The better the strength development in the initial stage, the more it can be used as an injection material suitable for the multi-stage steel pipe construction method. As a result of laboratory test, it was found that the homogel time of the injection material using circulating resources required more time than the mixing ratio using cement as the injection material. In addition, it was found that the initial strength curing time satisfying 2MPa was required for more than 24 hours. Therefore, it was confirmed that the injection material using recycled resources required a longer initial curing time than cement of the same mixing ratio.

Analysis of Dynamic Characteristics in Two-stage Injection for CRDi Injectors Based on AMESim Environment (AMESim기반 CRDi용 인젝터의 2단분사 동적거동 특성해석)

  • Jo, In-Su;Kwon, Ji-Won;Lee, Jin-Wook
    • Journal of ILASS-Korea
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    • v.17 no.2
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    • pp.57-63
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    • 2012
  • For reduction of CO, NOx and soot emission emitted by diesel diffusion combustion, the authors focused on injection actuator to improve fuel availability inside combustion chamber. In this study, it was investigated the internal dynamic characteristics of two-stage injection with diesel injectors with different driving type for the common rail direct injection by using the AMESim simulation code. The analysis parameter defined such as fuel pressure, injection hole's diameter and driven voltage. As the results, it was shown that the piezo-driven injector had a faster response and had better control capability than the solenoid-driven injector. It was found the piezo-driven injector can be utilized effectively as multiple injector than solenoid-driven injector.

A Study on the Prediction of the Final Weight for the Injection Molded Rectangular Plates (사각판 사출성형품의 최종무게 예측에 관한 연구)

  • Lee, Chang-Hoon;Yoon, Kyunghwan
    • Journal of the Korean Society for Precision Engineering
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    • v.13 no.9
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    • pp.130-137
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    • 1996
  • In the present paper the effect of various process conditions on the final weight of injection molded rectangular plates has been investigated in detail. The main parameters involved in the simulations were melt temperature, mold temperature, injection speed and packing pressure. The dimensions of the plate used were 100mm long, 2mm of width and polystyrene was used as a molding material. The shear viscosity of the polymeric material was treated as a function of shear rate, temperature and pressure through the whole processes including packing and cooling stages. By increasing a packing pressure the final weight of sample increased linearly. Furthermore, as the melt temperature, the mold temperature and the injection speed increased, the final weight of the injection molded plate decreased within the molding window.

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Efficacy of Intra-articular Hyaluronic Acid Injection in Early Stage Ankle Osteoarthritis (초기 족관절 골관절염 환자에서의 히알루론산 관절강 내 주사 요법)

  • Lee, Doo-Hyung;Kim, Tae-Hun;Han, Seung-Hwan
    • Journal of Korean Foot and Ankle Society
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    • v.15 no.1
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    • pp.27-31
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    • 2011
  • Purpose: This study evaluated the efficacy of an intra-articular injection of sodium hyaluronate in the treatment of early stage osteoarthritis of the ankle. Materials and Methods: Early stage ankle osteoarthritis (Takakura stage I and II) patients who received hyaluronic acid injection therapy were retrospectively reviewed. Patients underwent intra-articular injections of 2 mL of sodium hyaluronate for 3 consecutive weeks. Clinical evaluation and Visual Analogue Scale (VAS) scoring were performed at every three months after treatment. Results: Total 27 patients were involved and mean age was 55 year old (range 33 to 77 years). There were 13 male and 14 female patients. Mean follow up duration was 13 month and. Pre-intra-articular VAS score was $8.9{\pm}0.7$ and three month follow up score was $3.8{\pm}2.8$. VAS score of last follow up was $3.2{\pm}3.4$. The effect of hyaluronic acid continued about one year when analyzed the VAS score change of the patients followed for more than one year. Patients' satisfaction was "very satisfied" in nine, "satisfied" in 12, "fair" in one, and "not satisfied" in five patients. Overall satisfaction rate was 82%. There were no ankle osteoarthritis stage changes in serial follow up radiograph. Conclusion: Symptomatic relief of signs and symptoms of osteoarthritis of the ankle was achieved by injection of an intra-articular hyaluronate injection. Efficacy of Hyaluronate acid injection persisted more than 1 year in our study. Intra-articular hyaluronate injection to ankle osteoarthritis is safe and effective as knee joint and should be considered as a valid conservative treatment for ankle osteoarthritis.