• Nuclear Engineering and Technology
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• 제21권1호
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• pp.1-11
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• 1989

원자로 정지동안에도, 잔열제거계통은 그 기능이 계속 유지되어야 하나, 실제로 가압 경수로에서 냉각상실고가 많이 발생되어 있다. 본 논문은 원자로 정지중의 냉각기능상실을 예방하고, 또한 냉각기능상실로 인한 노심손상의 중대성을 완화시키기 위한 대책을 강구하기 위한 시도로서, 전형적인 가압경수로에 대한 사고/고장 수목과 운전원실수 확률을 위한 HCR 모델, 초기 사상의 빈도를 위한 2단계 bayesian 방법 및 고장난 계통의 회복 활률을 위한 계단함수 모델 등을 이용한 원자로 정지 위해도 모델을 개발하여, 잔열제거계통의 신뢰도를 분석하였다. 그 결과는 원자로가 정지 중일 때의 위해도가 운전중일 때 이것에 비해 별로 낮지 않은 것으로 나타났으며, 몇 가지의 설계개선을 통하여 냉각기능상실로 인한 노심 손상확률을 상당히 낮출 수 있는 것으로 나타났다.

• 한국안전학회지
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• 제33권5호
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• pp.157-163
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• 2018

This paper describes design improvement to a research rector for safety enhancement using Probabilistic Safety Assessment (PSA). This PSA under reactor design was undertaken to assess the level of safety for the design of a research reactor and to evaluate whether it is probabilistically safe to operate and reliable to use. The scope of the PSA reported here is a Level 1 PSA, which addresses the risks associated with the core damage. The technical objectives of this study were to identify accident sequences leading to core damage and to derive design improvement from the dominant accident sequences through the sensitivity analysis. The AIMS-PSA and FTREX were used for the this PSA of the research reactor. The criterion for inclusion was all sequences with a point estimate frequency greater than a truncation value of 1.0E-14/yr. The final result indicates a point estimate of 6.79E-05/yr for the overall Core Damage Frequency (CDF) attributable to internal initiating events for the research reactor under design. Based on the dominant accident sequences from the PSA, the seven kinds of sensitivity analysis were performed and some design improvement items were derived. When the five methods to improve the safety were all applied to the reactor design and emergency operating procedure, its risk was reduced to about 1.21E-06/yr from 6.79E-05/yr. The contribution of LOCA and LOEP with high CDF were significantly reduced by the sensitivity analysis. The safety of the research reactor was well improved and the risk was reduced than before adapting the design improvement gotten from the sensitivity analysis. The present study indicated that the research reactor has the well-balanced safety in regard to each initiating event contribution to CDF. The PSA methodology is very effective to improve reactor safety in a conceptual design phase and especially, Risk-informed design(RID) is very nice way to find the deficiencies of research reactor under design and to improve the reactor safety by solving them.

• Journal of Radiation Protection and Research
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• 제41권2호
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• pp.117-121
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• 2016

Background: Definition and grouping of initiating events (IEs) are important basics for probabilistic safety assessment (PSA). An IE in a spent fuel reprocessing plant (SFRP) is an event that probably leads to the release of dangerous material to jeopardize workers, public and environment. The main difference between SFRPs and nuclear power plants (NPPs) is that hazard materials spread diffusely in a SFRP and radioactive material is just one kind of hazard material. Materials and Methods: Since the research on IEs for NPPs is in-depth around the world, there are several general methods to identify IEs: reference of lists in existence, review of experience feedback, qualitative analysis method, and deductive analysis method. While failure mode and effect analysis (FMEA) is an important qualitative analysis method, master logic diagram (MLD) method is the deductive analysis method. IE identification in SFRPs should be consulted with the experience of NPPs, however the differences between SFRPs and NPPs should be considered seriously. Results and Discussion: The plutonium uranium reduction extraction (Purex) process is adopted by the technics in a model reprocessing plant. The first extraction cycle (FEC) is the pivotal process in the Purex process. Whether the FEC can function safely and steadily would directly influence the production process of the whole plant-production quality. Important facilities of the FEC are installed in the equipment cells (ECs). In this work, IEs in the FEC process were identified and categorized by FMEA and MLD two methods, based on the fact that ECs are containments in the plant. Conclusion: The results show that only two ECs in the FEC do not need to be concerned particularly with safety problems, and criticality, fire and red oil explosion are IEs which should be emphatically analyzed. The results are accordant with the references.

• 한국환경과학회지
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• 제23권4호
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• pp.553-560
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• 2014

The rainfall-runoff characteristics in Jeju Island significantly differ from those in inland, due to highly permeable geologic features driven by volcanic island. Streams are usually sustained in the dry conditions and thereby the rainfall-runoff characteristics changes in terms of initiating stream discharge and its types, depending highly on the antecedent precipitation. Among various the rainfall-runoff characteristics, lag time mainly used for flood warning system in river and direct runoff ratio for determining water budget to estimate groundwater recharge quantity are practically crucial. They are expected to vary accordingly with the given antecedent precipitation. This study assessed the lag time in the measured hydrograph and direct runoff ratio, which are especially in the upstream watershed having the outlet as $2^{nd}$ Dongsan bridge of Han stream, Jeju, based upon several typhoon events such as Khanun, Bolaven, Tembin, Sanba as well as a specific heavy rainfall event in August 23, 2012. As results, considering that the lag time changed a bit over the rainfall events, the averaged lag time without antecedent precipitation was around 1.5 hour, but it became increased with antecedent precipitation. Though the direct run-off ratio showed similar percentages (i.e., 23%)without antecedent precipitation, it was substantially increased up to around 45% when antecedent precipitation existed. In addition, the direct run-off ration without antecedent precipitation was also very high (43.8%), especially when there was extremely heavy rainfall event in the more than five hundreds return period such as typhoon Sanba.

• Industrial Engineering and Management Systems
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• 제12권4호
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• pp.336-350
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• 2013

This paper proposes a mathematical modeling-based approach for assessing disaster effects and selecting suitable mitigation alternatives to provide humanitarian relief (HR) supplies, shelter, rescue services, and long-term services after a disaster event. Mitigation steps, such as arrangement of shelter and providing HR items (food, water, medicine, etc.) are the immediate requirements after a disaster. Since governments and non-governmental organizations (NGOs) providing humanitarian aid need to know the requirements of relief supplies and resources for collecting relief supplies, organizing and initiating mitigation steps, a quick assessment of the requirements is the precondition for effective disaster management. Based on satellite images from weather forecasting channels, an area/dimension of the disaster-affected zones and the extent of the overall damage may often be obtained. The proposed approach then estimates the requirements for HR supplies, supporting resources, and rescue services using the census and other government data. It then determines reliable transportation routes, optimum collection and distribution centers, alternatives for resource support, rescue services, and long-term help needed for the disaster-affected zones. A numerical example illustrates the applicability of the model in disaster mitigation planning.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2002년도 국제심포지움
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• pp.1-19
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• 2002

It is well established that the initiating event in chemical carcinogenesis is the binding of reactive carcinogens to DNA. Thus, a number of analytic methods have been developed for determining levels of carcinogen-DNA adducts in humans as a marker of individual exposure and, potentially, of risk for cancer development. In addition, reactive carcinogens also bind to protein suggesting protein adducts can be used as a surrogate for DNA adducts in some situations. We have developed monoclonal and polyclonal antibodies to carcinogen-DNA and protein adductis and highly sensitive ELISA and immunohistochemical assays for determining levels of adducts in human tissues. These studies have demonstrated higher levels of adducts in those with higher exposure as a result of workplace, dietary, chemotherapy, environmental of lifestyle (smoking) exposures. Elevated levels of adducts have been found in lung and liver cancer cases compared to controls. We have also used DNA adducts to determine efficacy of an antiosidant vitamin intervention. DNA adduct studies have demonstrated very different levels of damage in those with similar exposure levels. These interindividual differences are likely the result genetic differences in capacity to activate carcinogens, detoxify reactive intermediates and repair DNA adducts once formed. We are currently investigating the relationship between polymorphisms in a number of these genes to determine their relationship to adduct levels as well as their ability to confer increased risk for cancer development. The ability to identify high risk individuals will allow the targeting of screening and preventive strategies to those most likely to benfit.

• Nuclear Engineering and Technology
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• 제49권2호
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• pp.426-433
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• 2017

This paper describes the development process, the innovative techniques used and insights gained from the latest integrated, full scope, multistate Level 2 PSA analysis conducted at the Leibstadt Nuclear Power Plant (KKL), Switzerland. KKL is a modern single-unit General Electric Boiling Water Reactor (BWR/6) with Mark III Containment, and a power output of $3600MW_{th}/1200MW_e$, the highest among the five operating reactors in Switzerland. A Level 2 Probabilistic Safety Assessment (PSA) analyses accident phenomena in nuclear power plants, identifies ways in which radioactive releases from plants can occur and estimates release pathways, magnitude and frequency. This paper attempts to give an overview of the advanced modeling techniques that have been developed and implemented for the recent KKL Level 2 PSA update, with the aim of systematizing the analysis and modeling processes, as well as complying with the relatively prescriptive Swiss requirements for PSA. The analysis provides significant insights into the absolute and relative importances of risk contributors and accident prevention and mitigation measures. Thanks to several newly developed techniques and an integrated approach, the KKL Level 2 PSA report exhibits a high degree of reviewability and maintainability, and transparently highlights the most important risk contributors to Large Early Release Frequency (LERF) with respect to initiating events, components, operator actions or seismic component failure probabilities (fragilities).

• Investigative Magnetic Resonance Imaging
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• 제21권1호
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• pp.43-50
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• 2017

Chronic expanding organizing hematoma (CEH) occasionally mimics a soft tissue tumor on MRI, which becomes more problematic in patients with a history of surgical resection for musculoskeletal malignancy. Herein, we present a case of CEH which we were able to differentiate from recurrent tumor through MRI follow-up, including diffusion-weighted imaging (DWI) and dynamic contrast enhanced (DCE) imaging. A 66-year-old male visited our institution under suspicion of recurrent leiomyosarcoma of the thigh, 19 months after surgery and radiation therapy. Due to inconclusive results, three US-guided biopsies and 6 MRI examinations were performed over 2 years. In the end, we could diagnose a CEH using conventional and functional MRI techniques, and it was histopathologically confirmed after surgical resection. A CEH may occur remotely after an initiating event, and it may persist and expand over several years. Functional MR sequences, in addition to conventional sequences, are helpful in differentiating CEH from malignant neoplasms.

• 농업과학연구
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• 제28권2호
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• pp.162-172
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• 2001

There have been various flower exhibitions in many countries such as Netherlands, Japan and China so as to encourage the growth of flower industry since they recognize the value of flower as cultural goods. Chungnam Province government, also endeavoring to make the. regional flower industry into high valued agriculture and exporting industry, plans to open the international flower exhibition in Anmyon-Do from April 26th, 2002. This flower show, first held by local government and featuring mega-event tourism, is expected to contribute to initiating flower industry and related business in Chungnam region. However, the flower exhibition may not be said to succeed if it does not play enough to trigger the role in expanding its effect on post growth of regional flower industry. This paper aimed at suggesting strategies of maintaining festival boom of post Anmyon-Do flower fair and contributing to take off of flower agriculture and its related industry as follows; 1) inviting various flower business activities into exhibition places 2) establishing flower village town attracted by tourists 3) devising the flower R&D center 4) organizing helping center for infant flower business group.

• Parasites, Hosts and Diseases
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• 제54권5호
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• pp.679-684
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• 2016

Clonorchiasis, caused by direct contact with Clonorchis sinensis worms and their excretory-secretory products (ESPs), is associated with chronic inflammation, malignant changes in bile ducts, and even cholangiocarcinogenesis. Our previous report revealed that intracellular free radicals enzymatically generated by C. sinensis ESPs cause NF-${\kappa}B$-mediated inflammation in human cholangiocarcinoma cells (HuCCT1). Therefore, the present study was conducted to examine the role of upstream Toll-like receptors (TLRs) on the initial host innate immune responses to infection. We found that treatment of HuCCT1 cells with native ESPs induced changes in TLR mRNA levels in a time-dependent manner, concomitant with the generation of free radicals. ESP-mediated free radical generation was markedly attenuated by preincubation of the cells with TLR1-4-neutralizing antibodies, indicating that at least TLR1 through 4 participate in stimulation of the host innate immune responses. These findings indicate that free radicals triggered by ESPs are critically involved in TLR signal transduction. Continuous signaling by this pathway may function in initiating C. sinensis infection-associated inflammation cascades, a detrimental event leading to progression to more severe hepatobiliary diseases.