• Title/Summary/Keyword: Inhibiting Effect

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A STUDY ON THE ANTIMICROBIAL EFFECT OF FLUORIDE-RELEASING REMOVABLE ORTHODONTIC APPLIANCES (불소유리 가철성 교정장치의 항균효과에 관한 연구)

  • Jang, Ki-Taeg
    • Journal of the korean academy of Pediatric Dentistry
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    • v.26 no.1
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    • pp.133-138
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    • 1999
  • To study the antimicrobial effect of fluoride-releasing removable orthodontic appliances, 0 wt%(Group 1), 5 wt%(Group 2) and 10 wt%(Group 3) of $CaF_2$ were added to orthodontic resin. The specimens were then put in media in which S. mutans and Lactobacillus, known cariogenic bacteria, were cultured. Inhibiting zones were measured 24, 48 and 72 hours later. The following conclusions were reached: 1 In the Lactobacillus media, no zone of inhibition was observed regardless of the time passed. 2. In the S. mutans media, zones of inhibition were observed after 48 hours. 3. S. mutans showed greater inhibition in Group 3 compared to Group 2, after 72 hours rather than 48 hours(p<0.01).

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Assessing the hydrogen peroxide effect along with sodium hypochlorite against marine blue mussels aimed at antifouling usage

  • Haque, Md. Niamul;Kwon, Sunghyun
    • Environmental Engineering Research
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    • v.22 no.1
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    • pp.108-115
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    • 2017
  • Chlorination has been the most common antifouling method, but alternatives are under searching. In this article, we report how the hydrogen peroxide could enhance the effect of chlorination to prevent fouling by inhibiting larvae settlement and abatement of mussel colonization or by extinct of them; through marine mussel Mytilus edulis. The addition of hydrogen peroxide shows synergic effect on the veliger larvae (up to 19 folds) and effectively reduces required time of mussel mortality by 8-22%. For resolution of micro- and macro-fouling caused by the marine mussel, as well as diminishing of time and conventional chlorine dose could be important factor in favour of environment and economics.

Effect of Amino Acids on Callus Induction from Bentgrass (아미노산이 Bentgrass 캘러스 유도에 미치는 영향)

  • Ming Liang Chai
    • Asian Journal of Turfgrass Science
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    • v.12 no.4
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    • pp.189-194
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    • 1998
  • The effect of proline, glutamine, aspartic acid and their combinations on callus induction and embriogenic callus formation from 3 creeping bentgrass (Agrostis palustris) cv. Regent, Mariner, Cato and 1 colonial bentgrass (Agrostis tenuis) cv. Tiger was estimated in both light and dark condition. The addition of amino acids to the growth medium did not have a significant stimulatory effect on the induction of embryogenic callus, instead, they were inhibitory, particularly at higher concentration (40 mM). But supplement of amino acids at lower concentrations (5 or 10mM) to basal medium was beneficial in inhibiting the formation of hairy outgrowth on the surface of embryogenic callus.

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Estimation of Flash Points of Flammable Liquid Mixtures with Non-flammable Liquids (난연성액체에 따른 가연성 액체혼합물의 인화점 추산)

  • 이수경;엄종호;하동명;이성민
    • Journal of the Korean Society of Safety
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    • v.7 no.3
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    • pp.53-59
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    • 1992
  • A general theory is developed which enables closed-cup flash points of mixtures of flammable and non-flammable liquid to be estimated from a knowledge of a certain properties of flammability diagram by thermodynamic method. The estimated equations is shown the effect of both the flame inhibiting properties of the vapor of the non-flammable component and the relative volatility of that component. The vapor phase flame inhibition effect results in a even greater elevation of flash points than the rotative volatility of that component. Especially in cases of similar vapor phase flame inhibition of the non-flammable component, the rotative volatility is affected greater elevation of flash points(extinguishing effect).

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Antimicrobial Activity of Extracts from Citrus Seeds (감귤류 종자 추출물의 향균활성)

  • 오혁수;박욱병;안용석;오명철;오창경;김수현
    • Culinary science and hospitality research
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    • v.9 no.4
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    • pp.69-80
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    • 2003
  • To develope natural food preservatives antimicrobial effect of the natural products against food-related bacteria and yeast The purpose of this study was evaluate antimicrobial effect of the citrus seeds. antimicrobial activities of methanol extracts from the citrus seeds investigate against Escherichia coli O26, Staphylococcus aureus 6358, Saccharomyces cerevisiae IBM 4274, Bacillus licheuiformis 9945a and Alcoligenes faecalis. Citrus seeds is containing to moisture 4∼6.5%, curd protein 11∼15%, curd lipid 32∼46%, curd carbohydrate 22∼45 % and ash 2∼4 %, that is containing to flavornoid 12∼48mg% and phenolic compound 22∼53mg%. Solidity content of the methanol extract from the citrus seeds was 0.8∼1.2%. Almost all of the methanol extracts from citrus seeds exhibited growth inhibiting activities for most of microorganisms tested. The methanol extracts from Citrus grandis, C. sunki, C. sulcata showed the growth inhibitory effects against Escherichia coli O26. The methanol extracts from C. obovoidea, C. sulcata, C. aurantium showed the growth inhibitory effects against Staphylococcus aureus 6358. The methanol extracts from C. obovoidea, C. sulcata, C. tangerina showed the growth inhibitory effects against Saccharomyces cerevisiae IBM 4274. The methanol extracts from C. obovoidea, C sunki, C. sulcata, C. tangerinan, C. natsudaidai, C. iyo, C. aurantium showed the growth inhibitory effects against Bacillus licheuiformis 9945a. The methanol extracts from C. obovoidea, C sunki, C. sulcata, C. aurantium showed the growth inhibitory effects against Alcoligenes faecalis. Among this especially, Showed growth inhibiting activity of the methanol extracts from Citrus sulcata that about microorganisms investigated. If apply searching suitable application method about such the citrus seeds antimicrobial activity, role as good antimicorbial material in storage or cooking of food, processing is expected.

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Screening of Natural Antimicrobial Edible Plant Extract for Dooboo, Fish paste, Makkoli Spoilage Microorganism (식용 식물로부터 얻은 추출물의 두부, 어묵, 막걸리 변질균에 대한 항균성 검색)

  • Ahn, Eun-Sook;Kim, Moon-Suk;Shin, Dong-Hwa
    • Korean Journal of Food Science and Technology
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    • v.26 no.6
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    • pp.733-739
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    • 1994
  • To extend the self-life of Dooboo (tofu), fish paste and Makkoli (Korean traditional rice wine) for which severe heat treatment are not expectable, main putrefactive microorganisms were isolated from each product and tested their growth inhibition by ethanol and water extracts of several edible plants. The ethanol extract of Phellodandron amurense Ruprs had the strong effect of growth inhibiting to all three isolates from Dooboo and Makkoli, and Eugenia caryophyllus, Pinus rigia Mill, Bletilla striata (Thunb) Reichb. Fill and Paeonia albiflora Pall were also same effect to isolates from fish paste. The ethanol extract was more effective inhibiting than water extract in all test microorganisms. The evident inhibition level of each extract was 2000 ppm of Pa ethanol for fish paste and 1000 ppm for Makkoli.

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Development of Functional Seasoning Agents from Skipjack Processing By-product with Commercial Pretenses 3. Storage Stability of Powdered Skipjack Hydrolysate (참치 가공부산물로부터 단백질 분해효소를 이용한 기능성 천연조미료 제재의 개발 3. 분말 참치 가수분해물의 저장중 품질안정성)

  • Cha, Yong-Jun;Kim, Eun Jeong;Kim, Hun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.4
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    • pp.627-631
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    • 1996
  • The antioxidative effects of BHT and rosemary on the hydrolysate from skipjack processing byproduct(SPB) was evaluated by storing at $30^{\circ}C$ for 60 days. Each of 0.02% BHT, 0.01% rosemary, and 0.02% rosemary was added into SPB hydrolysate prior to spray drying and the dried powder was tightly sealed in the laminated film(PET/Al foil/CPP, $5\mu\textrm{m}/15\mu\textrm{m}/70\mu\textrm{m})$ bags for storage. The colometric lightness("L") decreased through the storage period in all treatments while the redness ("a") showed the opposite trend. Changes of pigment were higher in level of hydrophillic brown than in lipophilic brown during storage. The effect of antioxidants, by adding BHT and rosemary, showed in TBA and POV during storage. Especially, the 0.02% rosemary treatment was more effective than 0.02% BHT treated SPB having effect of angiotensin converting enzyme(ACE) inhibiting.yme(ACE) inhibiting.

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Toxicity Reduction of VOCs by Catalytic Oxidation Mechanism (VOCs의 촉매산화 메커니즘에 의한 독성 저감효과)

  • 이재동
    • Journal of environmental and Sanitary engineering
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    • v.15 no.3
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    • pp.88-93
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    • 2000
  • The objective of this study was to depict the kinetic behavior of the platinum catalyst for the deep oxidation of VOCs and their mixture. The oxidation characteristics of VOCs, which were benzene, toluene, and styrene, was studies on a 0.5% $Pt/{\gamma}-Al_2O_3$ catalyst. The reactivity increases in order benzene>toluene>styrene. In mixtures, remarkable effects on reaction rate and selectivity have been evident ; the strongest inhibiting effect was shown by styrene and increases in a reverse order with respect to that of reactivity. The reaction model reveals that there is a competition between the two reactants for the oxidized catalyst. Thus, the nontoxic catalytic oxidation process was suggested as the new VOCs control technology.

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Adenophora remotiflora protects human skin keratinocytes against UVB-induced photo-damage by regulating antioxidative activity and MMP-1 expression

  • Kim, Hye Kyung
    • Nutrition Research and Practice
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    • v.10 no.4
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    • pp.371-376
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    • 2016
  • BACKGROUND/OBJECTIVES: Chronic ultraviolet (UV) exposure-induced reactive oxygen species (ROS) are commonly involved in the pathogenesis of skin damage by activating the metalloproteinases (MMP) that break down type I collagen. Adenophora remotiflora (AR) is a perennial wild plant that inhabits Korea, China, and Japan. The present study investigated the protective effects of AR against UVB-induced photo-damage in keratinocytes. MATERIALS/METHODS: An in vitro cell-free system was used to examine the scavenging activity of 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical and nitric oxide (NO). The effect of AR on ROS formation, antioxidant enzymes, elastase, MMP-1 level, and mRNA expression of MMP-1 were determined in UVB-irradiated human keratinocyte HaCaT cells. RESULTS: AR demonstrated strong DPPH free radical and NO scavenging activity in a cell-free system exhibiting $IC_{50}$ values of 1.88 mg/mL and 6.77 mg/mL, respectively. AR pretreatment dose-dependently attenuated the production of UVB-induced intracellular ROS, and antioxidant enzymes (catalase and superoxide dismutase) were enhanced in HaCaT cells. Furthermore, pretreatment of AR prevented UVB-induced elastase and collagen degradation by inhibiting the MMP-1 protein level and mRNA expression. Accordingly, AR treatment elevated collagen content in UVB-irradiated HaCaT cells. CONCLUSION: The present study provides the first evidence of AR inhibiting UVB-induced ROS production and induction of MMP-1 as a result of augmentation of antioxidative activity in HaCaT human keratinocytes. These results suggest that AR might act as an effective inhibitor of UVB-modulated signaling pathways and might serve as a photo-protective agent.

Curcumin Analogue A501 induces G2/M Arrest and Apoptosis in Non-small Cell Lung Cancer Cells

  • Xia, Yi-Qun;Wei, Xiao-Yan;Li, Wu-Lan;Kanchana, Karvannan;Xu, Chao-Chao;Chen, Da-Hui;Chou, Pei-Hong;Jin, Rong;Wu, Jian-Zhang;Liang, Guang
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.16
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    • pp.6893-6898
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    • 2014
  • Curcumin and its analogues have been reported to exert anti-cancer activity against a variety of tumors. Here, we reported A501, a new curcumin analogue. The effect of A501 on cell viability was detected by MTT assay, the result showed that A501 had a better inhibiting effect on the four non-small cell lung cancer (NSCLC) cells than that of curcumin. Moreover, Colony forming experiment showed A501 significant restrained cell proliferation. Flow cytometry displayed A501 can cause G2/M arrest and induce apoptosis. Western blotting showed that A501 decreased the expression of cyclinB1, cdc-2, bcl-2, while increased the expression of p53, cleaved caspase-3 and bax. In conclusion, curcumin analogues A501 played antitumor activity by inhibiting cell proliferation and inducing apoptosis of NSCLC cells. And it was likely to be a promising starting point for the development of curcumin-based anticancer drugs.