• Title/Summary/Keyword: Inhalant abuse

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Systematic Review of Vitamin B12 Regimen for Patient with Subacute Combined Degeneration of the Spinal Cord Following Nitrous Oxide Abuse (아산화질소 남용에 의한 척수의 아급성 연합변성 환자에서 Vitamin B12의 투여방법에 대한 체계적 고찰)

  • Chung, Jin Seok;Choa, Min Hong;Chung, Sung Phil;Park, In Cheol
    • Journal of The Korean Society of Clinical Toxicology
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    • v.17 no.2
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    • pp.79-85
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    • 2019
  • Purpose: The purpose of this study is to evaluate the effectiveness of vitamin B12 treatment in subacute combined degeneration (SCD) caused by nitrous oxide (N2O) abuse. Methods: Relevant literature was accessed through PubMed, EMBASE, Scopus, and KoreaMed. All the literature that was relevant to human use of vitamin B12 treatment for SCD caused by N2O abuse was included. Case reports were excluded if the treatment regimens were not precisely described. The literature search was conducted by two investigators during September 2019 for the final publication period. The languages of the publications were restricted to English and Korean. Results: Twenty-three published articles that contained 24 cases were included. Sixteen cases among them were treated with intramuscular vitamin B12 of 1 mg/day and the rest received different doses or routes. Although most cases described significant clinical improvements, one case showed no beneficial effect due to the patient's noncooperation. Another case showed adverse events, including spinal myoclonus, following vitamin B12 therapy. Conclusion: Vitamin B12 has been broadly used for the treatment of SCD caused by N2O abuse. However, most of the relevant studies were case reports that reported various regimens of vitamin B12 administration. Further studies are needed to establish a standard regimen of vitamin B12 because the incidence of N2O abuse may increase in South Korea.

The Literature Review of Inhalant Abuse (휘발성류 흡입제 남용에 관한 문헌적 연구)

  • 장진경
    • Journal of Families and Better Life
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    • v.13 no.1
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    • pp.168-178
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    • 1995
  • 본 논문의 목적은 휘발성류 흡입제 남용에 대한 문헌들을 고찰하고, 이러한 고찰을 통하여 휘발성류 흡입제 남용에 관한 실태와 연구분야의 취약점에 대해 논의하고자 한다. 본 논문에서는 휘발성류 흡입제 남용에 관한 문헌들을 세부분으로 나누어 고찰하고자 한다. 첫번째는 휘발성류 흡입제 남용에 대한 의학적 접근으로써 흡입제 남용으로 인한 다양한 증상들에 대해 고찰하고자한다. 두번째 영역은 휘발성류 흡입제 남용에 관한 행동학적 접근으로써 흡입제 남용이 미래의 다른 약물중독을유발시키는지에 대해 논의하고자 하며, 또한 휘발성류 흡입제 사용이 청소년들에게 반 사회적 행동을 유발시키는지를 판명하고자 한다. 세번째 영역은 휘발성류 흡입제 남용이 가족학적 접근으로써 흡입제중독을 유발시키는가 족환경에 대해 고찰하고자 한다. 이러한 연구들을 통하여 본 연구자는 휘발성류 흡입제 남용자에 관한 연구에 있어서의 취약점을 지적해 보고 휘발성류 흡입제 남용자에 대한 미래의 연구방향을 제시하고자 한다. 마지막으로 휘발성류 흡입제 및 약물남용에 대한 예방 및 사후 대책을 제안함으로써 결론을 짓고자 한다.

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A Study on Health condition and Drug use of Female Workers in Incheon area (산업장 여성 근로자의 건강과 약물사용)

  • Cho Wonsun
    • Journal of Korean Public Health Nursing
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    • v.9 no.2
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    • pp.17-32
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    • 1995
  • The purpose of this study is to promote health for young female workers. It is based on questionnaires collected from 215 female workers in Incheon area. This study includes health condition (fatigue scores), occupational disease, knowledge of abused drugs and the actual condition of drug use. The results are summerized as follows: - $47.4\%$ visited their health center and were treated with diseases like cold and headache $(34.9\%)$, gastroenteric disease $(6.5\%)$, trauma $(7.9\%)$ and chronic disease such as diabetes and hypertension $(3.3\%)$ - $44.7\%$ received regular health education and $4.7\%$ among them received education on abused drugs. - $20.5\%$ were suffering from work related diseases such as gastroenteric disease, headache, trauma, repiratory disease, skin problem, arthritis, low back pain, shortsightness and tuberculosis. - Total mean fatigue score as an indication of health status was $9.0\pm5.4$ points out of 30 points. Physical mean score (group I) was $3.92\pm2.2$ points and psychological mean score was $2.5\pm2.3$ points and neurosensory mean score was $2.6\pm2.1$ points out of each 10 points. - They recognized analgesics $(55.0\%)$ and the next are laxatives $(49.8\%)$, inhalants $(40.0\%)$, narcotics $(24.2\%)$, stimulants $(24.0\%)$, antihistamines$(5.9\%)$, diuretics $(3.0\%)$, tranquilizer $(2.4\%)$ and sedatives $(1.4\%)$ - They used analgesics $(37.2\%)$ the most and then laxatives $(6.0\%)$, stimulants$(5.6\%)$, diuretics $(1.9\%)$, antihistamines$(0.5\%)$, And nobody used tranquilizer, sedatives, narcotics and inhalant. - The relationship between career, drug abuse education, health center utilization and and the actual condition of drug using was examined. The longer the career and the more educated with drug abuse, the less drug used. And those who utilized health center rarely used more drugs. - The relationship between career, health center utilization, the score of fatigue and use of analgesics was also examined. Those group who have a longer career above 3 years and the group who have never used health center used more analgesics. And the group of fatigue score above 11.0 points used a little more analgesics than the other group. These results indicate that analgesics are the most frequent used drugs among female workers. Those analgesics such as geborin, penzal, saridon, aspirin, tyrenol should be used properly. These basic data is submitted for the education and consultation which are carried out by industrial nurses for promoting health of industrial workers.

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