• Journal of Korean Academy of Nursing
• /
• v.37 no.3
• /
• pp.353-364
• /
• 2007

Purpose: This study is aimed to analyze and clarify the ambiguous concept of insight. Method: This study used the process of Walker & Avant's concept analysis. Results: Insight can be defined in terms of its attributes as follows: Insight 1) comes as a release to the tension of inquiry, (2) is the outcome of the process to discover the overall structure of the problem situation and psychologically restructurize it, (3) comes suddenly and unexpectedly, (4) is to clearly perceive the solution of the abstract problem, and (5) promotes obtaining another new insight. The antecedents of insight include inquiry that can not be resolved easily and also a state where basic knowledge related to the inquiry can be utilized. The consequence of the insight is (1) a new judgement is made, (2) the problem is solved, (3) previous insight is retained and transferred, and it also facilitates the generation of fresh insight, and (4) it passes into the habitual texture of one's mind. Conclusion: Nurse educators need to facilitate nursing students and nurses to accumulate systematically, various information that can become the basis of insight and provide them with an opportunity to experience a variety of problems. In addition, it is important to provide questions to learners as an education strategy to allow them to gain insight into problem solving. From now on, insight needs to be studied in conjunction with critical thinking and questioning in order to enhance nurses' ability to resolve problems.

• BMB Reports
• /
• v.42 no.3
• /
• pp.166-171
• /
• 2009

Hsp70s assist in the process of protein folding through nucleotide-controlled cycles of substrate binding and release by alternating from an ATP-bound state in which the affinity for substrate is low to an ADP-bound state in which the affinity for substrate is high. It has been long recognized that the two-domain structure of Hsp70 is critical for these regulated interactions. Therefore, it is important to obtain information about conformational changes in the relative positions of Hsp70 domains caused by nucleotide binding. In this study, analytical ultracentrifugation and dynamic light scattering were used to evaluate the effect of ADP and ATP binding on the conformation of the human stress-induced Hsp70.1 protein. The results of these experiments showed that ATP had a larger effect on the conformation of Hsp70 than ADP. In agreement with previous biochemical experiments, our results suggest that conformational changes caused by nucleotide binding are a consequence of the movement in position of both nucleotide- and substrate-binding domains.

• Fisheries and Aquatic Sciences
• /
• v.13 no.4
• /
• pp.343-349
• /
• 2010

The effects of osmotic stress on the non-specific immune response of Nile tilapia, Oreochromis niloticus, were investigated. Osmoregulatory mechanism of tilapia has been studied, but less information is available about innate immune response of O. niloticus faced with hyperosmolality. Acute osmotic stress was elicited by transferring tilapia from freshwater (FW) to 24 psu seawater (SW). Non-specific immune parameters including lysozyme activities of plasma and head kidney (HK), alternative complement pathway (ACP) activity in plasma, phagocytic capacities of spleen and HK immune cells, and respiratory burst activity of immune cells in both HK and spleen were analyzed. Lysozyme activities were increased at 1 h and 30 h after transfer to SW, but decreased at 10 h after SW transfer. Conversely, ACP activity increased 10 h after SW transfer. Phagocytic capacity increased slightly at 1 h and 5 h after SW transfer, and respiratory burst activity showed an increase in superoxide release at 10 h after SW transfer. Taken together, these results indicate that the exposure of tilapia to hyperosmotic conditions has immunostimulatory effects on cellular and humoral immune reactions.

• Journal of Power System Engineering
• /
• v.9 no.1
• /
• pp.5-13
• /
• 2005

Acoustic emission(AE) is defined as the transient elastic waves thar are generated by the rapid release of energy. The advantage of AE is that very early crack growth can be detected well before a highly stressed component may fail. At present, an exact diagnosis is the most reliable means for determining the soundness of structures during power plant operations. AE monitoring has been applied successfully in power plants to determine mechanical problems, pressure vessel integrity and external valves leaks, vacuum leaks, the onset of cavitation in pumps and valves, the presence of flow(or no flow) in piping and heat exchange equipment, etc. Acoustic emission(AE) technology has recently strengthened its application base, and practitioners' understanding of the technique's fundamentals. This paper introduces the methods of a survey and assessment on AE monitoring applications in nuclear, fossil and hydraulic power plant. The main objective of this paper was to obtain information on various applications of AE technology in power plant.

• Journal of the Korean Society for Aviation and Aeronautics
• /
• v.28 no.1
• /
• pp.45-58
• /
• 2020

According to the Ministry of Land, Infrastructure and Transport press release ('18.12.21.) The amendment of the Aviation Business Act will reduce the capital requirements for aviation leisure operators and make it easier to enter aviation leisure businesses by improving regulations on small air transportation business. In addition, as the scale of the UAV(Unmanned Aerial Vehicle) sector is expected to increase globally, the dramatic increase in low altitude operating aircraft, including this, must be taken into account. The low altitude aircraft category is divided into small airplanes, helicopters, light aircrafts and ultra-light aircrafts, and instructors include school instructor pilots and student pilots, military and national helicopter pilots, and aviation leisure operators. In case of low altitude aircraft, there are cases of canceling operations due to low visibility and low clouds, and aircraft accidents due to excessive operation and sudden weather phenomenon. Therefore, in order to prevent low-altitude aircraft accidents, a safe flight plan based on weather conditions and weather forecasts and more accurate and local weather forecasts and weather forecast data are needed to prepare for the rapidly changing weather conditions.

• Journal of Pharmacopuncture
• /
• v.23 no.1
• /
• pp.1-7
• /
• 2020

Nicotine, primary component of tobaco produces craving and withdrawal effect both in humans and animals. Nicotine shows a close resemblance to other addictive drugs in molecular, neuroanatomical and pharmacological, particularly the drugs which enhances the cognitive functions. Nicotine mainly shows its action through specific nicotinic acetylcholine receptors located in brain. It stimulates presynaptic acetylcholine receptors thereby enhancing Ach release and metabolism. Dopaminergic system is also stimulated by it, thus increasing the concentration of dopamine in nuclear accumbens. This property of nicotine according to various researchers is responsible for reinforcing behavioral change and dependence of nicotine. Various researchers have also depicted that some non dopaminergic systems are also involved for rewarding effect of nicotinic withdrawal. Neurological systems such as GABAergic, serotonergic, noradrenergic, and brain stem cholinergic may also be involved to mediate the actions of nicotine. Further, the neurobiological pathway to nicotine dependence might perhaps be appropriate to the attachment of nicotine to nicotinic acetylcholine receptors, peruse by stimulation of dopaminergic system and activation of general pharmacological changes that might be responsible for nicotine addiction. It is also suggested that MAO A and B both are restrained by nicotine. This enzyme helps in degradation dopamine, which is mainly responsible for nicotinic actions and dependence. Various questions remain uninsurable to nicotine mechanism and require more research. Also, various genetic methods united with modern instrumental analysis might result for more authentic information for nicotine addiction.

• Archives of design research
• /
• v.11 no.1
• /
• pp.33-42
• /
• 1998

The movie, (Jurassic Park) made by ultramodern Computer Graphics has earned 100 million dollors admission fee in 9 days after opening release and has earned 3000 million dollors that add direct income to relative field income composed by fancy industry, theme park, and so on. If you compare the income with hollywood movies with ours total amount of export, you will know the contents industry scale Many countries weight on contents industry in national supports movies, now. All image softwares that have same target movies, computer game, animation, etc. compress to contents to entertainment and was expected to secure the superiority on the 21th ultramodern media industry. The one have hegemony 21th information period if how much have the contents by the dizital broadcasting. But meaning of intercultural communication play on important part more value of contents than value of political and economical aspect.

• Nuclear Engineering and Technology
• /
• v.31 no.1
• /
• pp.68-79
• /
• 1999

The YGN Units 3&4 plant conditions during shutdown operation were reviewed to identify the possible event scenarios following the loss of shutdown cooling (SDC) event. For the five cases of typical reactor coolant system (RCS) configurations under the worst event sequence, such as unavailable secondary cooling and no RCS inventory makeup, the thermal hydraulic analyses were performed using the RELAP5/MOD3.2 code to investigate the plant behavior following the event. The thermal hydraulic analyses include the estimation of time to boil, time to core uncovery, and time to core heat up to determine the containment closure time to prevent the uncontrolled release of fission products to atmosphere. The result indicates that the containment closure is recommended to be achieved within 42 minutes after the loss of SDC for the steam generator (SG) inlet plenum manway open case or the large cold leg open case under the worst event sequence. The containment closure time is significantly dependent on the elevation and size of the opening and the SG secondary water level condition. It is also found that the containment closure needs to be initiated before the boiling time to ensure the survivability of the workers in the containment. These results will provide useful information to operators to cope with the loss of SDC event.

• Proceedings of the National Institute of Ecology of the Republic of Korea
• /
• v.1 no.1
• /
• pp.83-89
• /
• 2020

Methods for detecting the presence of genetically modified (GM) crops are evolving to comply with legislation and to enhance monitoring by biotechnology companies and regulators. In order to cover a broad range of detection methods for a new GM crop, conventional multiplex PCR methods are required. Based on the genetic information on three GM alfalfa varieties (J101, J163, and KK179), which were recently approved in South Korea, we developed a fast, reliable, and highly specific multiplex polymerase chain reaction (PCR) method with basic PCR equipment and inexpensive reagents. To validate and verify the newly developed multiplex PCR method, we applied a limit of detection assay and random reference material analysis. We also monitored the unintentional environmental release of GM alfalfa in South Korea by performing the multiplex PCR analysis with 91 feral alfalfa specimens collected from 2000 to 2018. Our methodology is a sensitive, simple, quick, and inexpensive tool for detecting and identifying three GM alfalfa varieties.

• Nuclear Engineering and Technology
• /
• v.35 no.3
• /
• pp.179-190
• /
• 2003

The multiple steam generator tube rupture (SGTR) event scenario with available safety systems was experimentally and analytically evaluated. The experiment was conducted on the large scaled test facility to simulate the multiple SGTR event and investigate the effectiveness of operator actions. As a result, it indicated that the opening of pressurizer power operated relief valve was significantly effective in quickly terminating the primary-to-secondary break flow even for the 6.5 tubes rupture. In the analysis, the recent version of RELAP5 code was assessed with the test data. It indicated that the calculations agreed well with the measured data and that the plant responses such as the water level and relief valve cycling in the damaged steam generator were reasonably predicted. Finally, sensitivity study on the number of ruptured tubes up to 10 tubes was performed to investigate the coolant release into atmosphere. It indicated that the integrated steam mass released was not significantly varied with the number of ruptured tubes although the damaged steam generator was overfilled for more than 3 tubes rupture. These findings are expected to provide useful information in understanding and evaluating the plant ability to mitigate the consequence of multiple SGTR event.