Cheol Ju Kim;Tae Young Kwak;Min Hyeok Bae;Hwa Kyoung Shin;Byung Tae Choi
Journal of Pharmacopuncture
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v.25
no.4
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pp.326-343
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2022
Neurological disorders represent a substantial healthcare burden worldwide due to population aging. Acorus gramineus Solander (AG) and Acorus tatarinowii Schott (AT), whose major component is asarone, have been shown to be effective in neurological disorders. This review summarized current information from preclinical and clinical studies regarding the effects of extracts and active components of AG and AT (e.g., α-asarone and β-asarone) on neurological disorders and biomedical targets, as well as the mechanisms involved. Databases, including PubMed, Embase, and RISS, were searched using the following keywords: asarone, AG, AT, and neurological disorders, including Alzheimer's disease, Parkinson's disease, depression and anxiety, epilepsy, and stroke. Meta-analyses and reviews were excluded. A total of 873 studies were collected. A total of 89 studies were selected after eliminating studies that did not meet the inclusion criteria. Research on neurological disorders widely reported that extracts or active components of AG and AT showed therapeutic efficacy in treating neurological disorders. These components also possessed a wide array of neuroprotective effects, including reduction of pathogenic protein aggregates, antiapoptotic activity, modulation of autophagy, anti-inflammatory and antioxidant activities, regulation of neurotransmitters, activation of neurogenesis, and stimulation of neurotrophic factors. Most of the included studies were preclinical studies that used in vitro and in vivo models, and only a few clinical studies have been performed. Therefore, this review summarizes the current knowledge on AG and AT therapeutic effects as a basis for further clinical studies, and clinical trials are required before these findings can be applied to human neurological disorders.
Purpose: Uncertainty and restrictions on daily life have increased fear, stress, and depression during the coronavirus disease 2019 (COVID-19) pandemic. Depression is the most common mental health problem in pregnant women. The purpose of this study was to evaluate the levels of fear and stress related to COVID-19 experienced by pregnant women, as well as their levels of depression, and to examine the factors associated with depression during pregnancy. Methods: This was a cross-sectional, correlational study conducted among 153 pregnant women who visited a maternity hospital in Busan, South Korea. A self-reported questionnaire was used for data collection from December 18, 2021 to March 8, 2022. Data were analyzed using descriptive statistics, the independent t-test, one-way analysis of variance, Pearson correlation coefficients, and multiple regression. Results: Pregnant women experienced a moderate level of fear related to COVID-19, with an average score of 21.55±4.90. The average score for depression during pregnancy was 14.86±11.10, with 50.3% of the participants experiencing depression (≥13). The factors associated with depression during pregnancy were fear of COVID-19, contact with a confirmed case of COVID-19, being in the third trimester of pregnancy, high stress levels due to difficulties experienced from social distancing measures, and unintended pregnancy. These five statistically significant factors explained 35.0% of variance in depression during pregnancy. Conclusion: Considering the prevalence of depression in pregnant women during the COVID-19 pandemic, it is necessary to develop interventions to reduce anxiety by providing correct information and alleviating the stress of social distancing.
Background: Equating is a statistical procedure used to create a common measurement scale across two instruments. Item-level information should be taken into consideration so that scores can communicate interchangeably across the instruments. Objects: To investigate a common measurement scale across two health-related quality of life questionnaires (HRQOL) applied to various cancer survivors who underwent palliative care in healthcare institutions. Methods: A total of 139 cancer survivors who underwent palliative care were recruited from two rehabilitation hospitals and an oriental medicine hospital. Participants consisted of various cancer survivors who presented to the sites for palliative care. They were asked to fill out Korean versions of the World Health Organization Quality of Life (WHOQOL-BREF) and EuroQOL-5 dimension (EQ-5D) questionnaires following the palliative care. For the item level comparison, the Rasch rating scale model was used to investigate how participants regarded individual test items of two instruments in relation to item difficulty calibrations. Results: All items except the three items fit the Rasch model. One item (anxiety/depression) of the EQ-5D and two items (dependence on medical aids and negative feelings) of the WHOQOL-BREF are misfit. The WHOQOL-BREF targets the survivors well, while the EQ-5D is able to target the survivors with lower HRQOL levels with some ceiling effects. By inspecting the item difficulty calibrations of the two instruments, five items of the WHOQOL-BREF are selected as common items in relation to the EQ-5D. These five items are considered compatible with each other. Differential item functioning (DIF) analysis reveals that the healthcare item of the WHOQOL-BREF vs the self-care item of the EQ-5D exhibits significant DIF. Conclusion: Findings suggest that one paired item should be taken into consideration when equating the WHOQOL-BREF and the EQ-5D applied to cancer survivors who underwent palliative care.
Heeyoung Moon;Minsoo Kim;Su Hyun Lim;Younbyoung Chae;In-Seon Lee
Korean Journal of Acupuncture
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v.40
no.2
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pp.44-53
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2023
Objectives : This study was conducted to reveal the relationship between multiple factors of traditional Korean Medicine diagnosis and consider the further probabilities of treating people with physical and mental problems not defined as diseases, which is called 'Mibyeong' in traditional Korean Medicine. Methods : 40 healthy participants were included in the observational clinical trial. The participants were asked to complete health questionnaires (e.g. State-Trait Anxiety Inventory, Pittsburgh Sleep Quality Index, Stress Response Inventory) and they went through a traditional diagnosis process, including four stages of diagnosis (looking, listening/smelling, inquiring, and pulse taking), by a Korean Medicine doctor. Both the Korean Medicine doctor and an artery tonometry device performed the pulse diagnosis. Results : Although all participants were healthy people with no history of disease, more than half of participants had a problem related with severe level of fatigue (n=19), sleep disturbance (n=26) and stress (n=27) status according to the related questionnaires. Participants diagnosed with phlegm syndrome by the Korean Medicine doctor showed significantly greater score in phlegm pattern questionnaires than participants who were not. However, there was little agreement between the doctor's pulse diagnosis and radial artery tonometry results. Conclusions : We conducted a pulse diagnosis and measured health-related information along with the traditional Korean Medicine diagnose procedure, including four stages of diagnosis, and we found a linkage between diagnosis of phlegm and the phlegm pattern questionnaire score. The results suggest that a number of healthy participants, with no disease diagnosed, have Mibyoung symptoms which need further clinical management. Thus, we suggest that Mibyoung management programs based on qualified diagnosis tools and traditional Korean medicine diagnosis procedures be developed, and that future research using various diagnostic tools be carried out on a large population.
Park, Jiyang;Jeong, Jaehwan;Yoon, Jinsu;Kim, Sungchul;Kim, Jiyeon;Lee, Hosang;Ryu, Ikhui;Gwon, Yeongmun
Journal of Auto-vehicle Safety Association
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v.14
no.1
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pp.26-31
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2022
Changwon City has the second highest accident rate with 79.6 according to the city bus accident rate. In fact, 250,000 people use the city bus a day in Changwon, The number of accidents is increasing gradually. In addition, a recent fire accident occurred in the engine room of a city bus (CNG) in Changwon, which has gradually expanded the public's anxiety. In the case of business vehicles, the government conducts inspections with a short inspection cycle for the purpose of periodic safety inspections, etc., but it is not in the monitoring stage. In the case of city buses, the operation records are monitored using Digital Tacho Graph (DTG). As such, driving records, methods, etc. are continuously monitored, but inspections are conducted every six months to ascertain the safety and performance of automobiles. It is difficult to identify real-time information on automobile safety. Therefore, in this study, individual automobile management solutions are presented through machine learning techniques of inspection results based on driving records or habits by linking DTG data and Vehicle Inspection Management System (VIMS) data for city buses in Changwon from 2019 to 2020.
Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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v.8
no.3
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pp.531-541
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2018
This study researched text mining and text network analysis to analyze the images of Nonghyup Insurance for consumers. With the recent development of social media, many texts are being produced and reproduced, and texts of social media provide important information to companies. Text mining and text network analysis are used in many studies to identify image of company and product. As a result of the text analysis, the positive image of the Nonghyup Insurance is safety and stability. Negative images of the Nonghyup Insurance is concern and anxiety. As a result of the textual network analysis, Centered mage of Nonghyup Insurance is safety and concern. This paper allows researchers to extract several lessons learned that are important for the text mining and text network analysis.
COVID-19 has brought major changes to school education. Although it was attempted to guarantee students' right to learn through romote learning, the limitations of remote learning compared to face-to-face classes were clear. Nevertheless, the method of remote learning is undoubtedly a learning method that needs to be continuously developed in terms of being able to consider separated time and space and enabling learners to learn individually and autonomously. Therefore, in this study, real-time romote learning cases were analyzed at the elementary school stage, and problems in real-time remote classes were discovered and improved through teacher interviews. The problems with real-time remote classes in elementary school unit classes examined through examples are: First, that the proportion of teacher activity is high due to the anxiety of the unfamiliar environment of remote classes, and second, even though it is a real-time interactive class, it It was impossible to provide feedback. As a solution to this, it is necessary to consider the basic class steps (introduction-deployment-organization) and the use of class tools to provide appropriate communication and feedback was suggested.
The 'education panic' is one of the most phenomenal social issue in the current Korean society. The explanations of it until now, however, are rather superficial in a way that they only describe apparent facts and its seriousness, rendering further examination of the psychological motivation of parents who are the protagonist of education panic necessary. With 548 elementary, middle, and highschool students and their parents, the present study has investigated the impact of parents' past experience of 'han', regret, and learning effect regarding education on their parenting style as well as on their children's academic experience. The result revealed that parents' learning effect was related with more affective/autonomous parenting style and reasonable expectation for their children's educational career. On the contrary, parents' 'han' and regret indicated relationship with hostile and controlling parenting style and also with blind intention toward their children's educational career. The negative emotions also seemed to increase their children's academic stress, and lower academic self-efficacy. Such results suggest that the extraordinary education panic in Korea is more than a simple quantitative matter of intensity. The psychological basis and motivation of the people included, a much more quantitative information, should be taken into account.
Background: Noise has been linked to an increased risk of various health issues, including stress, anxiety, insomnia, and cardiovascular disorders. However, research on the relationship between residential traffic noise and mental health in South Korea is limited. Objectives: This study aims to examine the correlation between regional traffic noise levels and mental health using an ecological study design. Methods: In this ecological study, all data were collected from the Korean Statistical Information Service. Traffic noise data in residential areas and the prevalence of mental health indices in 44 cities with noise monitoring stations were obtained. Pearson correlation coefficients were calculated to assess the relationship between regional traffic noise levels and mental health indices. Results: Daytime traffic noise levels were found to have a positive correlation with stress perception (r=0.428, p=0.004) and showed a borderline positive correlation with depressive symptom prevalence (r=0.273, p=0.073). In cities with airports, significant correlations was observed between 24-hour average noise levels and depressive symptoms (r=0.604, p=0.010), whereas this relationship was not observed in cities without airports (r=0.048, p=0.813). Multiple regression analysis, which adjusted for factors such as age, gender ratio, smoking, obesity, unemployment, urban size, and the presence of an airport, confirmed the relationship between 24-hour average noise levels and stress perception (beta=0.287, p=0.024). Conclusions: This study identified correlations between regional traffic noise levels and depressive symptoms or stress perception in adults, with a more pronounced effect in areas with airports. These findings suggest a potential impact of residential traffic noise on mental health, highlighting the importance of preventive measures like noise management in urban planning to promote mental well-being.
Background: Adherence to antiretroviral treatment (ART) is crucial for maintaining the HIV-RNA suppression in patients living with HIV/AIDS. This study aims to analyze the risk factors contributing to low medication adherence among individuals with HIV/AIDS by analyzing data from the Korean HIV/AIDS cohort study. Methods: The dependent variable is ART medication adherence. The depressive symptom and anxiety scores were collected as main independence variables. Covariates included gender, age, transmission route, alcohol and smoking information, and antiviral treatment regimen details. To predict the relationship between ordinal dependent variables and independent variables, an ordered logistic regression analysis was conducted, and odds ratios (OR) were calculated. Results: The results of the ordered logistic regression analysis showed that female was associated with a higher risk of low medication adherence (OR=2.91, 95% CI=1.08, 7.83). Among the subjects who were non-smokers and non-drinkers, the risk of low medication adherence was lower (OR=0.36, 95% CI=0.18, 0.70). Depending on the ART treatment group, individuals taking integrase inhibitor had a lower risk of medication adherence (OR=0.31, 95% CI=0.13, 0.76), and those experiencing depressive symptoms were related with a higher risk of low medication adherence (OR=1.97, 95% CI=1.12, 3.46). Conclusions: The encouragement and emotional support of healthcare professionals are essential for patients living with HIV/AIDS who experience depressive symptoms to maintain ART adherence. Additionally, further research is needed to ensure that HIV/AIDS infected female with concurrent depressive symptoms can achieve appropriate ART therapeutic effect.
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