• 한국응용과학기술학회지
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• 제39권6호
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• pp.812-823
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• 2022

본 연구의 목적은 간호대학생의 의료 관련 감염 예방 지식과 감염관리 자신감, 표준주의 실행도 간의 관계를 확인하고 표준주의 실행도에 미치는 영향을 파악하기 위한 서술적 연구이다. 자료 수집은 2018년 10월4일부터 10월 12일까지 G 광역시에 소재한 간호대학생 160명을 대상으로 진행되었다. 연구결과 표준주의 실행도는 감염예방 지식(r=.27, p<.001), 감염관리 자신감(r=.52, p<.001)과 정의 상관관계가 있는 것으로 나타났고, 감염예방 지식은 감염관리 자신감((r=.27, p=012)과 유의한 상관관계가 있는 것으로 나타났다. 간호대학생의 표준주의 실행도에 영향을 미치는 요인은 감염관리 자신감(𝛽=0.45, p<.001), 피부 접촉 경험이 없는 경우(𝛽=0.18, p<.004), 감염예방 교육을 받은 경우(𝛽=-2.65, p<.009), 감염예방 지식(𝛽=0.15, p<.019) 순으로 나타났으며 모형의 설명력은 35%로 나타났다. 본 연구 결과를 토대로 간호대학생의 표준주의 실행도를 높이기 위하여 감염예방 지식과 감염관리 자신감을 높일 수 있는 표준주의 프로그램을 개발하여 시행하는 것이 필요하다.

• 한국콘텐츠학회논문지
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• 제13권5호
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• pp.295-302
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• 2013

치과진료실내에서 감염관리의 주체가 되는 예비 치과위생사인 치위생과 학생들을 대상으로 치면세마 실습 시 감염관리에 대한 인식태도 실천을 조사하여 학교에서부터 감염관리에 대한 지식도와 실천도가 어느 정도 지켜지고 있는지 분석하여 학교에서의 감염관리를 엄격히 하고 나아가 이를 토대로 치과 진료실에서의 감염관리 실천을 적용할 수 있도록 하는데 본 연구의 목적이 있다. 현재 감염방지 예방에 대한 현황에 대한 결과 먼저 b형 간염 예방 접종 여부에 대해서는 전체 불이행이 55.0%, 이행 45.0%의 순으로 나타났고, 치면세마 실습 시 환자내원 시 전신질환 문진 여부에 대해서는 이행이 88.6%로 나타났으며, 감염방지 교육여부에 대한 결과는 91.6%가 이행하고 있어 예방적인 측면도 대부분 잘 이행하고 있는 것으로 나타났다.

• Parasites, Hosts and Diseases
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• 제53권6호
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• pp.777-783
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• 2015

The nitric oxide (NO) formation and intrinsic nitrosation may be involved in the possible mechanisms of liver fluke-associated carcinogenesis. We still do not know much about the responses of inducible NO synthase (iNOS) induced by Clonorchis sinensis infection. This study was conducted to explore the pathological lesions and iNOS expressions in the liver of mice with different infection intensity levels of C. sinensis. Extensive periductal inflammatory cell infiltration, bile duct hyperplasia, and fibrosis were commonly observed during the infection. The different pathological responses in liver tissues strongly correlated with the infection intensity of C. sinensis. Massive acute spotty necrosis occurred in the liver parenchyma after a severe infection. The iNOS activity in liver tissues increased, and iNOS-expressing cells with morphological differences were observed after a moderate or severe infection. The iNOS-expressing cells in liver tissues had multiple origins.

• Parasites, Hosts and Diseases
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• 제56권6호
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• pp.589-596
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• 2018

Ticks are the vectors of various pathogens, threatening human health and animal production across the globe. Here, for the first time we detected Ricketssia spp., Borrelia spp. and protozoan in ticks from Poyang Lake region in Jiangxi Province of eastern China. In 3 habitat categories and on 12 host species, 311 ticks from 11 species were collected. Haemaphysalis longicornis was the predominant species, accounting for 55.63%, followed by Rhipicephalus microplus, Haemaphysalis flava and Ixodes granulatus. Of the collected ticks, 7.07% were positive for tick-borne pathogens, and H. longicornis and H. flava were found to be co-infected with Ricketssia spp. and protozoan. H. flava was the most detected positive for tick-borne pathogens, whereas H. longicornis had the lowest infection rate, and the difference in infection rates between tick species was significant (${\chi}^2=61.24$, P<0.001). Furthermore, adult ticks demonstrated remarkably greater infection rate than immature ticks (${\chi}^2=10.12$, P=0.018), meanwhile ticks on Erinaceidae showed significantly higher positivity than ticks collected on other host species (${\chi}^2=108.44$, P<0.001). Genetic fragment sequencing and analyses showed at least 4 pathogen species presence in ticks, namely Borrelia yangtzensis, Rickettsia slovaca or Rickettsia raoultii related genospecies, Babesia vogeli and Hepatozoon canis or Hepatozoon felis related genospecies. The finding indicates that the abundant ticks can carry diverse pathogens in Poyang Lake region, and pathogen infection is highly related to species, vertebrate hosts and life stages of ticks.

• Journal of Medicine and Life Science
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• 제20권2호
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• pp.67-72
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• 2023

Carbapenem-resistant Enterobacteriaceae (CRE) infections have increased rapidly over the past decade and are recognized as a severe health threat in Korea and worldwide. This study aimed to identify the status and characteristics of CRE infection in Jeju province and provide important basic data for the prevention and management of CRE infection. A descriptive epidemiological analysis was performed on reported cases of CRE infection in Jeju Province between 2018 and 2021 using the integrated management system for disease, an infectious disease reporting system from the Korea Disease Control and Prevention Agency. The annual difference and distribution trends of CRE infection were analyzed using CRE isolates, carbapenemase-producing CREs (CP-CRE) and their genotypes, and the type of medical institution in Jeju Province. CRE infections steadily increased in Jeju from 2018 to 2021, and the proportion of CP-CRE among the CREs also showed a statistically significant increase each year. Among the CRE isolates, Klebsiella pneumoniae (KPC, 62.13%) was the most common, and among the CP-CRE genotypes, KPC (81.62%) showed the highest distribution and increased each year. As the distribution of CP-CRE in have increased over the past 4 years, measures to prevent the spread and outbreak of CRE infections are warranted. The results of this study are expected to be used as basic data for prevention and management of CRE infections in the province.

• Parasites, Hosts and Diseases
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• 제48권2호
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• pp.113-120
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• 2010

To understand protozoan, viral, and bacterial infections in diarrheal patients, we analyzed positivity and mixedinfection status with 3 protozoans, 4 viruses, and 10 bacteria in hospitalized diarrheal patients during 2004-2006 in the Republic of Korea. A total of 76,652 stool samples were collected from 96 hospitals across the nation. The positivity for protozoa, viruses, and bacteria was 129, 1,759, and 1,797 per 10,000 persons, respectively. Especially, Cryptosporidium parvum was highly mixed-infected with rotavirus among pediatric diarrheal patients (29.5 per 100 C. parvum positive cases), and Entamoeba histolytica was mixed-infected with Clostridium perfringens (10.3 per 100 E. histolytica positive cases) in protozoan-diarrheal patients. Those infected with rotavirus and C. perfringens constituted relatively high proportions among mixed infection cases from January to April. The positivity for rotavirus among viral infection for those aged $\leq$ 5 years was significantly higher, while C. perfringens among bacterial infection was higher for $\geq$ 50 years. The information for association of viral and bacterial infections with enteropathogenic protozoa in diarrheal patients may contribute to improvement of care for diarrhea as well as development of control strategies for diarrheal diseases in Korea.

• 치위생과학회지
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• 제22권2호
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• pp.108-114
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• 2022

Background: Students in the department of dental hygiene are exposed to injections and sharp instruments during clinical practice. Therefore, it is necessary to develop measures for a safe practice environment. This study aimed to investigate dental stabbing accidents caused by dental instruments during clinical practice among students in the department of dental hygiene and suggest appropriate preventative measures. Methods: This study was conducted from May 1 to June 30, 2016, with students in the department of dental hygiene located at several universities in Seoul and Gyeonggi area. The study included 339 participants. A frequency analysis was performed to determine the general characteristics of dental infection control. A cross-analysis was conducted to identify the relationship between dental infection control education, stabbing accident prevention education, and treatment after stabbing accidents with a dental instrument. Results: Among the participants, 81.1% received dental infection control education and 66.4% received stabbing accident prevention education. Only 50.9% received hepatitis B vaccinations. Conclusion: Dental infection control education and stabbing accident prevention education were shown to be effective in preventing dental instrument stabbing in students. However, post-accident processing, such as reporting to upper management and medical treatment after the accident, was insufficient. Therefore, it is necessary to present a treatment flowchart for dealing with stab accidents in clinical practice for students in the department of dental hygiene and strengthen education.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.4953-4960
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• 2013

Primary liver cancer is one of the most common cancers at the global level, accounting for half of all cancers in some undeveloped countries. This disease tends to occur in livers damaged through alcohol abuse, or chronic infection with hepatitis B and C, on a background of cirrhosis. Various cancer-causing substances are associated with primary liver cancer, including certain pesticides and such chemicals as vinyl chloride and arsenic. The strong association between HBV infection and liver cancer is well documented in epidemiological studies. It is generally acknowledged that the virus is involved through long term chronic infection, frequently associated with cirrhosis, suggesting a nonspecific mechanism triggered by the immune response. Chronic inflammation of liver, continuous cell death, abnormal cell growth, would increase the occurrence rate of genetic alterations and risk of disease. However, the statistics indicated that only about one fifth of HBV carries would develop HCC in lifetime, suggesting that individual variation in genome would also influence the susceptibility of HCC. The goal of this review is to highlight present level of knowledge on the role of viral infection and genetic variation in the development of liver cancer.

• 한국방사선학회논문지
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• 제6권5호
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• pp.321-333
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• 2012

본 연구는 방사선사의 병원감염관리에 대한 인지도와 수행도를 파악하여 병원감염관리 방안의 개선 및 교육을 위한 기초자료를 제공하기 위해 실시한 연구이다. 연구대상자의 병원감염관리에 대한 인지도와 수행도의 평균 평점은 150점 만점으로 인지도 141.05점과 수행도 138.15점으로 모든 영역에서 인지도가 높을수록 수행도가 높은 정상관계를 보였으나 인지도에 비해 수행도가 전체적으로 낮음을 확인 할 수 있었다. 인지도에 영향을 미치는 요인으로는 감염관리 교육의 필요성, 감염예방 교육여부, 환자의 질병상태 인지 여부 등으로 통계적으로 유의하게 나타났고, 수행도에 영향을 미치는 요인으로는 감염예방 교육여부, 환자의 질병상태 인지여부, 인지도 등으로 통계적으로 유의하게 나타났다.

• Parasites, Hosts and Diseases
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• 제51권3호
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• pp.357-361
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• 2013

Several epidemiological surveys have reported the prevalence of Toxoplasma gondii infection in stray cats in Korea, but little information is available on T. gondii infection in household cats. The aim of the present study was to assess the prevalence and risk factors of T. gondii infection among household cats reared in Seoul, Korea. A total of 474 blood samples were collected from clinically healthy household cats. All samples were tested using ELISA and PCR. The risk factor analysis was based on a questionnaire filled out by the owners. The overall positive rate for ELISA and PCR assays was 2.2% (10/437) and 2.1% (10/474), respectively. With regard to the origin of cats, the positive rates among cats adopted from the animal shelter and veterinary clinic for stray cats were significantly different (P<0.05). Our study demonstrated that the positive rate of T. gondii infection in household cats was low and that this low prevalence was assumed to be associated with keeping the cats indoors and restriction of eating raw food and uncooked meat. Therefore, we suggest that the owners check the origin of the cats prior to adoption to prevent infection of other animals, including humans.