• 가정∙방문간호학회지
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• 제23권2호
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• pp.166-176
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• 2016

Purpose: The purpose of this study was to investigate the knowledge and prevention attitudes of female North Korean refugees regarding cervical cancer and human papillomavirus(HPV) infection. Methods: A descriptive study was conducted. Data were collected from November 2015 to March 2016 and 130 female North Korean refugees participated. Data were analyzed using SPSS 21.0. Results: Score on knowledge and prevention attitudes regarding cervical cancer and HPV were 2.53 out of 8 points, 1.67 out of 17 points, and 28.90 out of 36 points. There were significant differences between entry duration, the number of children, previous cervical cancer tests, Precognition about HPV, preferred education method, and knowledge of cervical cancer. There were significant differences between previous cervical cancer tests, Precognition about HPV and knowledge of HPV. The correlation between knowledge and prevention attitudes regarding cervical cancer and HPV was significant positive. Conclusion: Female North Korean refugees' knowledge level of cervical cancer and HPV is very low. However, their attitudes towards prevention was higher. These results imply a need for education, aimed at guiding North Korean female refugees, so as to enhance their knowledge regarding cervical cancer and HPV, and to promote their sexual health.

• Parasites, Hosts and Diseases
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• 제50권3호
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• pp.229-231
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• 2012

Toxoplasma gondii is a zoonotic parasite resulting in human infections and one of the infectious pathogens leading to uveitis and retinochoroiditis. The present study was performed to assess T. gondii infection in 20 ocular patients with chronic irregular recurrent uveitis (20 aqueous humor and 20 peripheral blood samples) using PCR. All samples were analyzed by nested PCR targeting a specific B1 gene of T. gondii. The PCR-positive rate was 25% (5/20), including 5% (1) in blood samples, 25% (5) in aqueous humor samples, and 5% (1) in both sample types. A molecular screening test for T. gondii infection in ocular patients with common clinical findings of an unclear retinal margin and an inflammatory membrane over the retina, as seen by fundus examination, may be helpful for early diagnosis and treatment.

• Parasites, Hosts and Diseases
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• 제52권4호
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• pp.443-447
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• 2014

Babesiosis is an emerging tick-borne disease in humans worldwide; however, little is known about the frequency of infection or prevalence of this disease in other parts of the world, excluding North America. In this study, we aimed to investigate Babesia microti infection frequency in a human population in Mongolia. One hundred blood samples were collected from stock farmers living in Khutul city of Selenge province, Mongolia. The sera and DNA from blood samples were evaluated for the presence of B. microti infection by using indirect fluorescent antibody (IFA) tests and PCR. The positive detection rates obtained using the IFA tests and PCR assays were 7% and 3%, respectively. This study is the first to detect of B. microti infections based on antibody seroprevalence or PCR assays for the presence of B. microti DNA in a Mongolian population.

• 지역사회간호학회지
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• 제24권4호
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• pp.398-406
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• 2013

Purpose: The study was conducted to clarify effects of a clonorchiasis prevention education program for clonorchiasis prevention lecturers. Methods: The research adopted a single group pretest-posttest design to see effects of the educational program to prevent Clonorchis sinensis infection. The subjects of this study were 74 clonorchiasis prevention lecturers from primary health care facilities. The pretest was conducted before the clonorchiasis prevention education program and the post test was done after the 2-day program in August, 2011. Descriptive statistics, t-test, and ANOVA were conducted to analyze the data. Results: The confidence level in Clonorchiasis management activities was improved significantly from $4.1{\pm}0.53$ points before the education to $4.4{\pm}0.46$ points after the education (t=-5.117, p<.001). The knowledge level about prevention of Clonorchis sinensis was improved significantly from $16.1{\pm}2.72$ points before the education to $18.3{\pm}1.14$ points after the education (t=-6.629, p<.001). Conclusion: The results suggest that the education program was effective in improving the confidence and knowledge levels in Clonorchiasis management activities for the clonorchiasis prevention lecturers. Based on the results of this study, continuous research on how the increased knowledge and confidence levels of Clonorchis sinensis prevention affect the prevalence of Clonorchis sinensis infection.

• 대한간호
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• 제18권5호통권103호
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• pp.73-83
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• 1979

This study was intended to provide fundamental data for some help of effective nursery management and for the prevention of hospital infection of infants by testing the contamination level of nursery room. The nursery room of the E. University Hospital wa

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제10권2호
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• pp.29-37
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• 2004

Recently the hospital infection with misappropriation of the antibiotic and absence of knowledge is aincreaseing trend. For this, medical treatment is confronting infection management guide. But so far there is no accurate standard or countermeasures. Since early 1990 Nosocomial Infection has not been looked over, although there is serious problem. After 90's understanding seriousness of Nosocomial Infection, many investigations have been done, but the relations of medical facilities were hardly investigated. This thesis shows the relation between facilities and Nosocomial Infection by documental references and the direction for intensive care unit through survey the recent general hospitals.

• 한국융합학회논문지
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• 제7권3호
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• pp.59-69
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• 2016

본 연구의 목적은 임상실습에 참여한 간호대학생들의 메르스에 대한 불안, 지식, 감염가능성, 감염예방가능성, 감염예방행위 이행수준을 파악함으로써 임상실습 중 발생할 수 있는 호흡기 감염 관리시스템의 융합적 구축에 기초자료를 제공하는데 있다. 본 연구는 서술적 조사연구로 2015년 6월 15일부터 6월 30일까지 임상실습 경험이 있는 간호학과 학생 222명을 대상으로 자료수집 하였다. 대상자의 특성과 메르스에 대한 불안, 지식, 감염가능성, 감염 예방 가능성, 감염예방행위 이행 수준을 설문조사하였고, 수집된 자료는 SPSS 18.0을 이용하여 기술통계, t-test, ANOVA, 상관관계, 다중회귀분석으로 분석하였다. 본 연구결과에서 나타난 평균 점수는 불안 42.70점(최대 80점), 지식 11.73점(16점 만점), 감염 가능성 22.55점(100점 만점), 감염예방가능성 7.37점(10점 만점), 감염예방행위 이행 정도 34.55점(최대 48점)이었다. 한편 감염예방행위 이행의 영향요인으로는 불안과 감염예방 가능성으로 나타나 메르스 유행 시 감염병에 대한 정보 제공과 감염예방 가능성을 교육하여 예방행위 이행을 증진시키도록 해야 한다.

• Journal of Microbiology and Biotechnology
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• 제19권3호
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• pp.323-330
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• 2009

Nontuberculous mycobacteria (NTM) are a major cause of opportunistic infections in immunocompromised patients, making the reliable and rapid identification of NTM to the species level very important for the treatment of such patients. Therefore, this study evaluated the usefulness of the novel target genes tuf and tmRNA for the identification of NTM to the species level, using a PCRrestriction fragment length polymorphism analysis (PRA). A total of 44 reference strains and 17 clinical isolates of the genus Mycobacterium were used. The 741 bp or 744 bp tuf genes were amplified, restricted with two restriction enzymes (HaeIII/MboI), and sequenced. The tuf gene-PRA patterns were compared with those for the tmRNA (AvaII), hsp65 (HaeIII/HphI), rpoB (MspI/HaeIII), and 16S rRNA (HaeIII) genes. For the reference strains, the tuf gene-PRA yielded 43 HaeIII patterns, of which 35 (81.4%) showed unique patterns on the species level, whereas the tmRNA, hsp65, rpoB, and 16S rRNA-PRAs only showed 10 (23.3%), 32 (74.4%), 19 (44.2%), and 3 (7%) unique patterns after single digestion, respectively. The tuf gene-PRA produced a clear distinction between closely related NTM species, such as M. abscessus (557-84-58) and M. chelonae (477-84-80-58), and M. kansasii (141-136-80-63-58-54-51) and M. gastri (141-136-117-80-58-51). No difference was observed between the tuf-PRA patterns for the reference strains and clinical isolates. Thus, a diagnostic algorithm using a tuf gene-targeting PRA is a promising tool with more advantages than the previously used hsp65, rpoB, and 16S rRNA genes for the identification of NTM to the species level.

• 한국산학기술학회논문지
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• 제21권3호
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• pp.360-369
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• 2020

본 연구는 요양병원 종사자들의 비말감염 예방 활동과 기침예절 지식을 비교하기 위해 시행되었다. 대상자는 A시의 3개 요양병원 종사자 177명이었다(의료인: 간호사 61명, 비의료인: 간호조무사와 요양보호사 116명). 자료는 2019년 3월 4일부터 29일까지 구조화된 질문지를 이용하여 수집되었다. 자료분석방법은 x²-test, Fisher exact test, independent t-test, ANOVA를 이용하였다. 분석결과, 의료인과 비의료인의 일반적 특성은 성별과 연령에서 두 집단간 유의한 차이를 나타냈다. 의료인과 비의료인의 비말감염 예방 활동은 평상 시 티슈 휴대, 평상 시 손수건 휴대, 평상시 마스크 휴대, 호흡기 증상 시 손수건 휴대, 손씻기 횟수, 기침예절 준수에서 통계적으로 두 집단 간 유의한 차이를 나타냈다. 기침예절 지식은 통계적으로 두 집단 간 유의한 차이를 나타냈다. 비의료인의 비말감염 예방 활동에 따른 기침 예절 지식 정도의 차이에서 평상 시 마스크 휴대, 기침예절 교육 유무에서 통계적으로 유의한 차이를 나타냈다. 본 연구를 통해 요양병원 종사자별로 기침예절에 관한 지식을 높이고 기침예절의 습관화를 위한 전략 마련이 필요하다.

• 대한약침학회지
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• 제26권1호
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• pp.18-26
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• 2023

Objectives: Terminalia chebula, the main ingredient of Altan Arur 5, has been used for many years in traditional medicine. This medicine is more effective than other drugs and is used to treat chronic gastritis and gastrointestinal disorders such as peptic ulcers and esophageal reflux. Other ingredients of Altan Arur 5 are Punica granatum (pomegranate), tulip seeds, black balm, and excreta of Trogopterus xanthipes. The main ingredients of T. chebula are antibacterial and analgesic in traditional medicine. Despite having been used for many years and although many studies have been conducted on the beneficial effects of this medicine and its ingredients, the toxicity of Altan Arur 5 has not yet been elucidated. Therefore, we aimed to study the toxicity of Altan Arur 5 to ensure that it is safe to use. Methods: Acute and chronic toxicity of Altan Arur 5 were assessed in 10 Kunming mice and 8 Sprague-Dawley rats, respectively, in different doses. In the acute toxicity study, Altan Arur 5 was orally administered to Kunming mice in doses of 12 g/kg, 24 g/kg, and 48 g/kg for 14 days. In the chronic toxicity study, it was orally administered to Sprague-Dawley rats in doses of 1.25 g/kg, 2.5 g/kg, and 5 g/kg for 12 weeks. Results: No significant differences were observed in the relative organ weights for mice treated with Altan Arur 5 compared with those in the control group. Furthermore, no macro- or microstructural changes were noted in the organs of any group. Conclusion: Our toxicity testing revealed that the traditional medicine Altan Arur 5 has no toxic effects in vivo.