• Korean Journal of Child Studies
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• v.22 no.2
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• pp.255-275
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• 2001

The purpose of this study was to construct a rating scale of infant and toddler development for the use of teachers in their observations of children during daily activities. The scale consists of 201 items measuring motor, self-help, socio-communicative, socio-emotional, and cognitive development. Quality, reliability and validity were examined with the use of a nation-wide sample of 1,245 children from classes of 1- and 2-year-olds. Tests on validity and reliability were high in terms of content validity evaluated by early childhood professionals, concurrent validity with the Bayley Scale, internal consistency among raters, and test-retest reliability. Factor analysis showed that the developmental areas of infants and toddlers are not clearly differentiated but are interrelated with each other. The scale was standardized by providing nation-wide norms with raw scores, percentiles, and standardized scores.

• The Journal of the Korea Contents Association
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• v.21 no.11
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• pp.179-192
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• 2021

Human beings going through a series of identification and adaptation steps from the external environment is deeply related to survival, and the physical and mental development process has the task of each growth period. In particular, infants and children are the most active time to take various information from the surrounding environment and develop balanced actions and thinking. Therefore, the space that supports the development of infants and children should be created into a meaningful environment beyond aesthetic and functional roles as a space that provides various senses and experiences. First, this study understood the concept of infant development and 'light environment' and analyzed the need. Second, the relationship between natural light and infants was identified. Third, the characteristics of the inflow of natural light applied to the space were derived by analyzing how the identified functions could be utilized, and based on this, the current status of daycare centers was analyzed to discuss the necessity and direction of 'introduction of natural light'. We hope that this study will be used as a meaningful basis for the active introduction of natural light in the future space design of daycare centers.

• Neonatal Medicine
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• v.18 no.2
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• pp.280-287
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• 2011

Purpose: The purpose of the present study was to determine the association of positive Ureaplasma urealyticum in gastric fluid with clinical features and outcomes in preterm infants. Methods: Gastric fluid from the preterm infants was first aspirated within 30 minutes and cultured within 24 hours after birth to check for U. urealyticum. Infants were divided into two groups on the basis of the presence/absence of U. urealyticum. Results: U. urealyticum in gastric fluid was identified in 17 of 91 (19%) preterm infants. Compared with the negative U. urealyticum group, there were significantly higher percentage of infants with gestational age ${\leq}$30 weeks (P=0.020), higher Apgar score at 1 minute and 5 minutes (P=0.017 and P=0.048, respectively), and higher rate of vaginal delivery (P=0.000) in the positive U. urealyticum group. Although the incidence rate of bronchopulmonary dysplasia between the two groups was not different, the frequency of bronchopulmonary dysplasia without previous respiratory distress syndrome was significantly higher in the positive group (11%) than that in the negative group (1%) (P=0.030). Conclusion: The detection of U. urealyticum in gastric fluid is more frequent in infants with gestational age ${\leq}$30 weeks. It can be helpful to predict the development of bronchopulmonary dysplasia without previous respiratory distress syndrome in preterm infants.

• Neonatal Medicine
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• v.16 no.2
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• pp.137-145
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• 2009

Purpose: The aim of this study was to determine the genotype frequencies of interleukin 10 (IL-10) gene polymorphisms and to investigate their association with the risk of respiratory distress syndrome (RDS) in preterm Korean infants. Methods: Two hundred fourteen preterm infants born at Ewha Womans University Mok Dong Hospital between November 2003 and July 2008 were studied. The cord blood of preterm neonates and the corresponding maternal blood were analyzed by PCR for IL-10 gene (IL-10 -1082A/G, -819T/C, and -592A/C) polymorphisms. The clinical data of patients were collected retrospectively by chart review. Results: The genotype frequencies of IL-10 genes in Korean mothers with preterm infants differ from other reports. The prevalence of two promoter SNPs of the IL-10 cytokine gene was similar but none had the IL-10-1082GG homozygote. Multiple logistic regression analysis demonstrated the risk of RDS to be significantly lower in the infants of the mothers with an IL-10-592AC/CC genotype than in those with an AA genotype (P=0.033). The risk of RDS was significantly lower in the mother with an IL-10-819TC/CC genotype than in those with a TT genotype (P=0.030). However, IL-10 polymorphisms in the cord blood were not significantly different in preterm infants with RDS compared with the preterm infants without RDS. When we compared the incidence of RDS and each IL-10A-1082G/T-819C/A-592C haplotype, the ACC haplotype had a protective effect on RDS (P=0.007). Conclusion: We conclude that the maternal IL-10-592A/C and IL-10-819T/C polymorphisms may have a role in the development of the RDS in preterm infants.

• Korean Journal of Child Studies
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• v.29 no.1
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• pp.15-32
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• 2008

The logical and mathematical thinking of 1- to 3-year-olds was studied by age groups at 6 month intervals; logical-mathematical thinking was examined by the two physical knowledge activities of cylinder rolling and making a slope. Results showed that in their early 1st year infants failed in both tasks. Infants in their late 2nd year showed understanding of 'rolling things' and 'non-rolling things' by comparing cylinders and cubes in the cylinder rolling activity and they showed 'spatial inference' by adjusting the position and direction of the cylinder so that the cylinder could roll properly and by adjusting the board on a block in the slope making activity. Three-year-old children rolled a cylinder and made a slope without difficulty.

• The Korean Journal of Emergency Medical Services
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• v.7 no.1
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• pp.29-42
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• 2003

The purpose of this study was to development CPR training course to promote wide spread training. The course objectives was based on international Guidelines 2000. The course presents information about the AHA adult Chain of survival and signs of heart attack, cardiac arrest, stroke, and chocking in adult, and includes information about healty heart living and actions to reduce the risk of cardiovascular disease. The course also presents information about the AHA infant and chila Chain of survival, signs of breathing emergencies and chocking in infants and children, prevention of sudden infant death syndrome, and prevention of the most common fatal injuies in infants and children. Vedio-mediated instruction is the primary approach to teaching psycomotor skills.

• Neonatal Medicine
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• v.16 no.1
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• pp.10-17
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• 2009

The immature neonatal brain is susceptible to the development of seizures. Seizures occur in 1% to 5% of infants during the neonatal period. Neonatal seizures are most commonly associated with serious acute illnesses, such as hypoxic-ischemic encephalopathy, birth trauma, metabolic disturbances, or infections. Thus, newborn infants with seizures are at risk for neonatal death and survivors are at risk for neurologic impairment, developmental delay, and subsequent epilepsy. Experimental data have also raised concerns about the potential adverse effects of the currently used anticonvulsants in neonates on brain development. Therefore, in the management of neonatal seizures, confirmatory diagnosis and optimal, but shorter, duration of anticonvulsant therapy is essential. Nevertheless, there has been substantial progress in understanding the developmental mechanisms that influence seizure generation and responsiveness to anticonvulsants. The currently used therapies have limited efficacy and the treatment of neonatal seizures has not significantly changed in the past several decades, This review includes an overview of current approaches to the treatment of neonatal seizures.

• Clinical and Experimental Pediatrics
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• v.55 no.9
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• pp.309-315
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• 2012

Human respiratory syncytial virus (HRSV) is a major cause of severe respiratory tract illnesses in infants and young children worldwide. Despite its importance as a respiratory pathogen, there is currently no licensed vaccine for HRSV. Following failure of the initial trial of formalin-inactivated virus particle vaccine, continuous efforts have been made for the development of safe and efficacious vaccines against HRSV. However, several obstacles persist that delay the development of HRSV vaccine, such as the immature immune system of newborn infants and the possible Th2-biased immune responses leading to subsequent vaccine-enhanced diseases. Many HRSV vaccine strategies are currently being developed and evaluated, including live-attenuated viruses, subunit-based, and vector-based candidates. In this review, the current HRSV vaccines are overviewed and the safety issues regarding asthma and vaccine-induced pathology are discussed.

• Proceedings of the IEEK Conference
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• 2009.05a
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• pp.129-131
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• 2009

Hearing loss is one of the most common birth defects among infants. Most hearing-impaired children are not diagnosed until one to three years of age, which is too late to treat for normal speech and language development. If a hearing impairment is identified and treated in its early stage, child's speech and language skills could be comparable to his or her normal-hearing peers. In this study, we applied the 'Fsp' method to distinguish between normal and impaired hearing. We have developed a battery-operated portable A - ABR(automated auditory brain stem response) system that automatically detects hearing impairment for neonates or infants in a nursery room, as well as in a sound-proof room. We partially validated the accuracy of the system in five normal-hearing adults.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.23 no.4
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• pp.175-180
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• 2012

Early detection and intervention is critical in improving prognosis of developmental disorders. Developmental delay can have many different causes and the clinical features of developmental delay are diverse according to its etiologic causes and severity. The vast and rapid growth of the child's neurobehavioral repertoire from birth through adolescence requires the physician's abundant experience, knowledge, and understanding of development. Here, we summarize instruments for use in neurodevelopmental assessment of infants and toddlers, focusing on motor development, which is the most frequent complaint listed in the developmental clinic.