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Inhibitory Effects of Seaweed Extracts on Growth of Malassezia furfur and Malassezia restricta

  • Choi, Jae-Suk;Lee, Bo-Bae;Joo, Chi-Un;Shin, Su-Hwa;Ha, Yu-Mi;Bae, Hee-Jung;Choi, In-Soon
    • Fisheries and Aquatic Sciences
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    • v.12 no.1
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    • pp.29-34
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    • 2009
  • Fifty seven species of common seaweed from the coast of Korea were screened for antifungal activity against Malassezia species. Seaweeds as a source of bioactive compounds are able to produce a great variety of secondary metabolites with different activities. There are numerous reports on the biological activities of seaweeds against human pathogens, fungi, and yeasts, but only few contain data regarding inhibitory effects against Malassezia sp., a major cause of dandruff and seborrheic dermatitis. To help address this paucity of information, this work was carried out to examine the antifungal effects of seaweed extracts against M. furfur and M. restricta. Of the fifty seven species of marine algae screened for their potential antifungal activity, only 17 species (29.8%) exhibited inhibitory activity. In agar disc diffusion method, the ether extracts of Corallina pilulifera, Enteromorpha linza, Laminaria japonica, Symphyocladia latiuscula and Ulva sp. showed strong antifungal activity. To identify major constituents in seaweed extracts, four selected extracts were analyzed on' a GC-MS equipped with a flame ionization detector, and compared to spectral data from databases WILEY229.LIB and NIST107.LIB. Most constituents in seaweed extracts are fatty acid-related compounds. When we evaluated any acute toxicity, the ether extracts of the selected four species were not toxic in mice. According to these results, it can be suggested that these seaweed extracts are valuable for the development of therapeutic agents in treating dandruff and seborrheic dermatitis. Further investigations to determine its bioactive compound(s) are currently in progress.

Establishment of mobile roadside fine dust monitoring system (이동형 도로변 미세먼지 모니터링 시스템 구축)

  • Kim, Han-Na;Kim, Si-Eung;Kim, Hyeok-Jung
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2021.07a
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    • pp.703-704
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    • 2021
  • 도로변에서 발생하는 미세먼지와 비산먼지는 인체에 각종 질병을 유발하는 발암물질로 알려져 있다. 본 논문에서는 효율적인 도로변 미세먼지의 농도를 측정을 위해 소형차량을 이용한 이동형 미세먼지 모니터링 시스템을 제안한다. 이 시스템은 기존의 대형차량의 운행으로 발행하는 미세먼지 사각지대를 해소하고, 고품질의 보급형 센서를 탑재하여 경제성을 제고한다. 또한, 미세먼지 측정 차량은 이동 중에도 실시간으로 측정가능하다. 이번 연구를 통해 미세먼지 측정 차량을 운행한 결과 도로변 상황을 즉각적으로 반영하는 결과를 나타내었다. 이러한 미세먼지 농도는 미세먼지 저감 및 관리를 위한 기초정보로 사용될 것을 기대한다.

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Study on e-Book Business Strategy in Information & Communication Industry (정보통신산업으로서 e-Book 비즈니스 전략)

  • Park, Jae-Sue;Kim, Hak-Jin;Ahn, Young-Jik
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.9
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    • pp.2057-2065
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    • 2014
  • New business The e-book industry is creating a convergence of ICT and printing culture. Even so, the system changes is not great in Korea. Global market players are going to creating a membership or community-type business model to take advantage of the terminal, platform, network, but the creative content production in Korea is limited. Since the discussion is limited to such devices or network services most, we suggest the possibility of modeling a multi-faceted. And the development of technology and services platform content is also important as a strategic approach to the development of the e-book industry. Most of all, we propose the application of content, technologies and services are developed.

Blind Hopping Phase Estimator in Frequency-Hopped FM and BFSK Systems

  • Kim, Myungsup;Seong, Jinsuk;Lee, Seong-Ro
    • ETRI Journal
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    • v.37 no.1
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    • pp.1-10
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    • 2015
  • A blind hopping phase estimator is proposed for the demodulation of received signals in frequency-hopping spread spectrum systems. The received signals are assumed to be bandwidth limited with a shaping filter, modulated as frequency modulation (FM) or binary frequency shift keying (BFSK), and hopped by predetermined random frequency sequences. In the demodulation procedure in this paper, the hopping frequency tracking is accomplished by choosing a frequency component with maximum amplitude after taking a discrete Fourier transform, and the hopping phase estimator performs the conjugated product of two consecutive signals and moving-average filtering. The probability density function and Cramer-Rao low bound (CRLB) of the proposed estimator are evaluated. The proposed scheme not only is very simple to implement but also performs close to the CRLB in demodulating hopped FM/BFSK signals.

Establishment of a mobile monitoring system for roadside fine dust vulnerable point (이동형 도로변 미세먼지 취약지점 모니터링 시스템 구축)

  • Kim, Hyeok-Jung;Kang, Min-Ji;Kim, Han-Na
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2022.07a
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    • pp.685-686
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    • 2022
  • 미세먼지는 인체에 직·간접적인 질병을 유발하는 1급 발암물질로 알려져 있다. 본 논문에서는 도로변에서 발생 되는 미세먼지 및 미세먼지 전구체 농도를 측정을 위한 이동형 미세먼지 모니터링 시스템을 제안한다. 이 시스템은 기존의 대형차량 대비 미세먼지 측정 사각지대를 해소하고, 성능등급 1등급 장비 및 온습도 보정 모듈 장착으로 결과의 높은 정확도를 확보하였다, 또한, 개발된 데이터 표출 시스템을 통해 미세먼지 측정 차량을 운행한 결과를 웹사이트에서 실시간 확인 가능하도록 하였다. 이동형 미세먼지 측정 차량 운영을 통해 얻어진 정보는 보행자를 위한 정보 제공 및 미세먼지 저감 및 관리를 위한 정책 마련의 기초정보로 사용될 것을 기대한다.

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A Study on the improvement through the present state analysis of the industry field training (산업체 현장실습 운영 현황 분석을 통한 개선 방안에 관한 연구)

  • Park, Kyung-Woo;Park, Ik-su
    • Journal of Engineering Education Research
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    • v.19 no.2
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    • pp.97-101
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    • 2016
  • This paper examines the industry field training education model, analyze the operational status proposed improvement measures. Data were analyzed using a field training participating students participating industry last three years. On the other hand analysis field training participating students increased, industry participation has decreased. And most of the students took part in the seasonal short-term job training. In addition, it was difficult to analyze the employment status field training operations follow-up member. In this paper, a field training operations support system management models and practical training courses organized field trips how to improve. Field training operations support will be strengthened through the work associated with the company expanding participation model introduced and is expected to increase in the long-term practical training, students participate in field training system improvement. Run the job training Improvement in future research presented in this paper attempts to analyze the students' employment status and results of operations involved.

Antioxidative Activities and Inhibition Effects on Oxidative DNA Damage of Valeriana fauriei (쥐오줌풀의 항산화 및 산화적 DNA 손상 억제 활성)

  • Park, Jae Ho;Jang, Tae Won;Lee, Seung Hyun
    • Korean Journal of Medicinal Crop Science
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    • v.24 no.6
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    • pp.464-470
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    • 2016
  • Background: Valeriana fauriei (Valerianaceae) has been used to as a traditional medicine to treat a variety of symptoms, including headache, insomnia, hypertension, and menstrual irregularity. However, the present study investigates the species' antioxidant activity and its inhibition of oxidative DNA damage, which have yet to be studied. Methods and Results: The antioxidant activity was assessed using radical scavenging assays with 1,1-diphenyl-2-picryl hydrazyl (DPPH) and, 2, 2'-azino-bis (3-ethylbenzothiazoline-6 sulfonic acid) diammonium salt (ABTS) and a reducing power assay. The total phenol content was also analyzed, and phenolic compounds were detected using HPLC/UV, whereas the inhibitory effect of Valeriana fauriei on oxidative DNA damage was measured using ${\phi}-174$ RF I plasmid DNA cleavage assay. The DPPH and ABTS radical scavenging activity were $75.17{\pm}3.55%$ and $95.83{\pm}0.63%$, repectively, and the reducing power was $93.14{\pm}1.74$ at $200{\mu}g/m{\ell}$. The total phenol content was $10.24{\pm}0.04mg/g$, whereas chlorogenic acid, catechin, caffeic acid and epicatechin were identified using HPLC/UV, and the ${\phi}-174$ RF I plasmid DNA cleavage assay indicated that V. fauriei provided protection against oxidative damage. Conclusions: The results of the present study suggest that V. fauriei has powerful antioxidant activity that can provide protective effects against the oxidative DNA damage caused by free radicals. The species, therefore, provides a valuable resource for the development of natural pharmaceutical to treat aging, cancer, and degenerative diseases.

Development and Validation of Dithiocarbamates Fungicide Analytical Method using CS2 Trap Method in Livestock Product (축산물 중 CS2 포집방법을 이용한 Dithiocarbamate계 살균제 분석법 개발 및 검증)

  • Jo, Hyeong-Wook;Sun, Jung-Hun;Heo, Hyo-Min;Lee, Sang-Hyeob;Kim, Jang-Eok;Moon, Joon-Kwan
    • Korean Journal of Environmental Agriculture
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    • v.40 no.2
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    • pp.127-133
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    • 2021
  • BACKGROUND: Dithiocarbamte fungicides have been used in crop cultivation for diseases protection and treatment. And cultivated agricultrual products were used as feedstuff, and residual pesticides are likely to be absorbed and transferred to livestock. But the maximum residue limits (MRLs) were not established for dithiocarbate fungicides in livestock products, and thus an analysis method was developed and validated for dithiocarbamate fungicides to establish MRLs. METHODS AND RESULTS: Samples were prepared using CS2 trap method and detected with UV/VIS spectrophotometer. Calibration line (0.1 ~ 10 ㎍/mL) was linear with r2 > 0.99. For validation, the recovery tests were carried out at three fortification levels (MLOQ, 10 MLOQ and 50 MLOQ) from livestock samples (egg, milk, beef, pork, and chicken). The results for mancozeb, propineb, and thiram ranged between 76.8 to 109.6%, 79.4 to 108.8%, and 80.2 to 107.8%, respectively and % RSD (relative standard deviation) values were below 9.5%. Furthermore, inter-laboratory analysis was performed to validate the method. CONCLUSION: All values were corresponded with the criteria ranges requested by both the CODEX (CAC/GL 40-1993, 2003) and MFDS guidelines (2016). This might be used as an official analytical method for determination of dithiocarbamate fungicides at established MRLs and monitoring.