• Journal of Sasang Constitutional Medicine
• /
• v.17 no.1
• /
• pp.155-161
• /
• 2005

1. Objectives The purpose of this study was to investigate the effects of administration of Indongdeungjikolpi-tang on the Soyangin Jungso(中消). 2. Methods To heal the Soyangin Jungso, we used Indongdeungjikolpi-tang(忍冬藤地骨皮湯). 3. Results Jungso of a Soyangin patient responded well to the treatment with Indongdeungjikolpi-tang. 4. Conclusions This case-study shows an efficient results by using Indongdeungjikolpi-tang in treatment of Soyangin Jungso(Diabetes Mellitus).

• The Korea Journal of Herbology
• /
• v.23 no.4
• /
• pp.103-112
• /
• 2008

Objectives: Indongdeungjikolpi-tang(IJT) is used as a traditional treatment of diabetes in oriental clinincs. This study aimed to evaluate the anti-diabetic effect of Indongdeungjikolpi-tang(IJT) in streptozotocin(STZ)-induced diabetic rats. Methods: Diabetes was induced by intraperitoneal injection of streptozotocin(STZ; 60 mg/kg BW) to Sprague-Dawley male rats. Experimental animals(six per group), were treated by oral administration of IJT(100 and 500 mg/kg BW) and glibendimide(3 mg/kg), a known antidiabetic drug for comparison, during 4 weeks. We measured the levels of glucose, insuline, triglyceride, creatinine and urea in sera of each group. An oral glucose tolerance test(OGTT) was also performed in all groups. Results: IJT(100 and 500 mg/kg) significantly reduced blood glucose levels and increased plasma insulin levels in STZ-induced diabetic rats. IJT also significantly reduced the plasma levels of tryglyceride, creatinine and urea in STZ-induced diabetic rats. The OGTT results showed a significant improvement in glucose tolerance in IJT-administrated rats. Conclusions: These data indicate that IJT may improve glocose homeostasis in STZ-induced diabetes, which could be associated with stimulation of insulin secretion.