• Journal of Pharmaceutical Investigation
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• 제20권1호
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• pp.19-28
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• 1990

Pharmacokinetic parameters of aminoglycosides are dependent on renal function, sex, age, hematocrit, fever, lean body weight (LBW) and disease states, etc. Therefore, the individual pharmacokinetic parameters such as half life $(t^{1/2})$ and volume of distribution(Vd) are needed to achieve optimal therapy. However these parameters had not been determined in Koreans. The purpose of this study was to evaluate the Vd and $t^{1/2}$ of amikacin in Korean patients who had normal renal function, to compare the mean values of study group with that reported in the literature and to compare the measured $t^{1/2}$ with the expected $t^{1/2}$ based on actual body weight (ABW), LBW and ideal body weight (IBW), respectively. Based on data, the Vd was greater than the literature and $t^{1/2}$ was similar to the literature. The predicted $t^{1/2}$ based on IBW was the closest to actual $t^{1/2}$. And postpartum patients had greater Vd than other group and had lower correlation between actual elimination rate constant and calculated creatinine clearance but higher correlation between actual elimination rate constant and Vd than other group.

• Journal of Nutrition and Health
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• 제34권7호
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• pp.748-753
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• 2001

This study is to investigate the effects of capsaicin with high-fat diet on tissue glycogen contents in exercise-trained rats. Forty male Sprague-Dawley rats were offered a high-fat diet for 2 wks in individual cages and were exercise-trained by a animal treadmill running throughout the experimental period. After 2 wks of the prefeeding with high-fat diet, the rats were divided into two group: high-fat diet group(CON)and high-fat diet + capsaicin(0.014%) group(CAP). The rats were killed by decapitation at 10 hr(rest), 1 hr and 2 hr after treadmill running(27m/min, 6$^{\circ}$). Body weight and epididymal adipose tissure weight were significantly lower in CAP than in CON, but soleus muscle weight was not different between the two groups. Glycogen contents in liver, soleus and gastrocnemius white muscles were significantly lower in CAP than in CON at rest, 1 hr and 2 hr (p<0.05). However, glycogen content in gastrocnemius red muscle was significantly higher in CAP compared with CON at 2 hr after the exercise(p<0.05). These results indicate that capsaicin intake with high-fat diet would decrease glycogen contents in liver and muscle, however, this effect on glycogen metabolism could be changed by muscle type.

• International Journal of Human Ecology
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• 제8권1호
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• pp.27-37
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• 2007

The purpose of this study is to investigate the preference of the hand and the sensibility image of underwear textiles according to seasons. According to a recent survey of 109 college students, using a 7 scale evaluation to the preference of the hand and the sensibility image among 13 summer and 10 winter underwear textiles. The data was analyzed through mean, SD, factor analysis, t-test, Person correlation analysis and regression analysis using SPSS Win 11.0. The summer underwear textiles were classified according to six tactile factors: stiffness/surface unevenness, weight, elasticity, moistness, extension, and warm-cool and 3 sensibility image factors: elegant individual, modern, and sporty-casual. The winter textiles were classified according to six tactile factors: stiffness/surface unevenness, elasticity, warm-cool, drapability, moistness and flexibility and divided into 2 sensibility images: modern elegant and sporty-casual. Factors expressing hand and sensibility image according to season showed significant difference. In the summer, weight, in the winter, drapability and flexibility showed significant difference at the hand factor evaluation. The hand factors: weight, warm-cool and modern sensibility image factors effect the preference of summer underwear textile, also the hand factors-elasticity, stiffness/surface unevenness and the sensibility image factor-easy-sport-casual-effect the preference of winter textiles. Therefore, the thin, light, and cool textiles which are also gorgeous and sporty-casual are preferred for summer underwear textiles while soft, simple and comfortable textiles are preferred for winter textiles.

• 성인간호학회지
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• 제23권2호
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• pp.146-159
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• 2011

Purpose: The purpose of this study was to investigate the effects of the internet based coaching program for obesity management on weight control related knowledge, self-efficacy, eating habits, physical activity and obesity related physiological indexes in hypertensive patients. Methods: The study design was non-equivalent control group pre-test-post-test design. A total of 43 subjects were overweight or obese hypertensive patients aged 30 or older, who were divided into experimental group (n=23) and control group (n=20). This program lasting 12 weeks consisted of a weight control related education, internet based individual coaching for diet, exercise and behavior modification, offering internet community and health counseling. The variables were measured three times (before the treatment, after 6 weeks, and after 12 weeks) and the collected data were analyzed by SPSS/WIN 17.0 program. Results: The experimental group had significantly improved weight control related knowledge, self efficacy, eating habits, body composition, and systolic blood pressure with time. Conclusion: The internet based coaching program was effective in improving obesity management, also this program will help to prevent cardiovascular disease of obese hypertensive patients.

• 한국의류학회지
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• 제9권2호
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• pp.57-65
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• 1985

In the experiment with a basic material for the design of summer wear that comfort can be obtained in temperature, to get individual differences, clothing styles (slacks, skirt), material differences(T/C, cotton), and the contrast between when naked and dressed, when two healthy females were dressed four kinds of summer wear as an object of experiment under the regular warm temperature environmental condition (24, 28, 32, $36^{\circ}C$, $60\pm10\%$ RH), the measurement of physiological, phychological change was taken and the result goes as follow; 1. Mean skin temperature rose by clothing, body weight loss decreased below $32^{\circ}C$, thermal sensation changed toward low temperature by $2\~3^{\circ}C$. 2. Mean skin temperature, body weight loss, the lowest blood pressure above $32^{\circ}C$, under-clothing temperature, and thermal sensation increased when in slacks to be compared with when in skirt. 3. Ambient temperature had a great effect on mean skin temperature, body weight loss, respiration, clothing surface temperature, under-clothing temperature and humidity, thermal sensation, etc. 4. It was admitted that pulse, thermal sensation, comfort show different individuality. 5. It was recognized that the lowest blood pressure, clothing surface temperature, under. clothing humidity differ according to the kinds of clothing. 6. A comfortable ambient temperature in clothing summer wear was about $27\~28^{\circ}C$.

• The Journal of Korean Physical Therapy
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• 제23권6호
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• pp.61-69
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• 2011

Purpose: This study investigated the changes in body composition and serum lipid composition in obese women that were caused by a 12-week circuit exercise regime including both field and aquatic activities. Methods: Subjects comprised a total of 36 women who had a BMI of more than $25kg/m^2$. The simple obesity group (n=17) had no current or past record of medical complications, whereas the group with complications (n=19) also suffered from hypertension and/or diabetes. The circuit exercise program consisted of 12 weeks of 60%HRmax exercise sessions, five days a week. Results: While changes in every variable of body composition were significant, there was no statistically significant difference in the changes in serum lipid composition variables. With the exception of BMI, the correlation between the simple/complicated groups and exercising was statistically insignificant. Conclusion: These findings suggest that while a complex circuit weight exercise program that includes aquatic exercises significantly and positively alters obese patients' body composition it does not create statistically significant changes in their serum lipid composition. It can still be concluded, however, that increasing the duration of the exercise program would be effective to influence this. Moreover, personalized exercise programs that fit the needs of the individual participants seem necessary, given that the effect of exercise on body composition and serum lipid composition was greater in patients with simple obesity than in those with complications.

• 디지털콘텐츠학회 논문지
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• 제17권5호
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• pp.359-366
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• 2016

유비쿼터스 환경에서 사용자에게 유용한 서비스를 제공하기 위해서는 시간과 공간을 기반으로 사용자의 행동과 선호 패턴을 고려하여 가장 적합한 데이터를 처리할 수 있는 방법이 필요하다. 실세계에서 사용자의 관심은 시간이 지남에 따라 변화할 수 있다. 그러므로 서비스 관심도의 변화를 중요도에 반영하여 정보를 추출할 수 있는 방법이 필요하다. 이 논문에서는 사용자에게 필요한 서비스 정보를 온톨로지로 설계하고 시간에 따라 동적으로 변화하는 사용자의 서비스 이용 패턴이나 데이터의 중요도를 동적 가중치로 표현하여 빈발 패턴을 찾는 방법을 제안한다. 이 논문에서 제안하는 동적 가중치를 고려하는 빈발 서비스 패턴 마이닝 기법은 시간의 변화에 따라 필요로 하는 사용자의 관심을 서비스의 중요도로 반영하므로 실시간의 최적화된 서비스 제공이 가능하다.

• Macromolecular Research
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• 제17권6호
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• pp.365-377
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• 2009

In this feature article, we briefly review the new methods we have utilized recently in the investigation of morphology and phase behavior of block copolymers. We first describe the chromatographic fractionation method to purify block copolymers from their side products of mainly homopolymers or block copolymer precursors inadvertently terminated upon addition of the next monomer in the sequential anionic polymerization. The chromatographic method is extended to the fractionation of the individual block of diblock copolymers which can yield the diblock copolymer fractions of different composition and molecular weight, which also have narrower distributions in both molecular weight and composition. A more detailed phase diagram could be constructed from the set of block copolymer fractions without the need of acquiring many block copolymers each prepared by anionic polymerization. The fractions with narrow distribution in both molecular weight and composition exhibit better long-range ordering and sharper phase transition. Next, epitaxial relationships between two ordered structures in block copolymer thin film is discussed. We employed the direct visualization method, transmission electron microtomography(TEMT) to scrutinize the grain boundary structure.

• 한국환경과학회지
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• 제12권11호
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• pp.1145-1157
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• 2003

The surface sediments inside Hallim Harbor, one of the major harbors of Jeju Island, were sampled three times (June, September and December, 2001) and analyzed for 16 polycyclic aromatic hydrocarbons (PAHs), recommended by US-EPA as priority pollutants, to assess their distribution levels and to suggest their possible origins. The concentrations of PAHs ranged from 19 to 496 ng/g on a dry weight basis with a mean value of 245 ng/g, and the levels were low to moderate in comparison with other areas in the world. Based on comparisons of individual and total PAH concentrations with effects-based and equilibrium partitioning-based on sediment quality guidelines, the potential for the biological effects were expected to be low. The sedimentary PAHs may be correlated with organic carbon and mud contents to some extent. From the examinations of the four PAH origin indices, such as LMW/HMW (low molecular weight 2-3 ring PAHs over high molecular weight 4-6 ring PAHs), phenanthrene/anthracene ratio, fluoranthene/pyrene ratio, chrysene/benzo〔a〕anthracene ratio, it can be concluded that the sediment PAH contaminations were ascribed to both pyrolytic and petrogenic origins.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제8권7호
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• pp.177-180
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• 2019

대표적인 취약점 스코어링 시스템은 CVSS다. 하지만 CVSS는 취약점이 자산에 미치는 영향성 관점을 평가 하지 않아 사용되지 않거나 중요도가 낮은 자산에 대해서도 동일한 우선순위로 처리해야하기 때문에 대규모 시스템의 위험도가 높은 취약점의 경우 효과적이고 신속한 대응을 할 수 없다. 시스템 구성을 계층화 하고, 계층 간의 그리고 계층내의 중요도에 따른 가중을 평가하는 영향성 관점의 평가 시스템인 계층적 가중 기반의 취약점 영향성 평가 스코어링 시스템을 제안한다.