While the prevalence of Helicobacter pylori (H. pylori) infection is decreasing in Korea, the incidence of gastric cancer remains high, emphasizing the importance of H. pylori eradication. A new treatment strategy is needed as the eradication rate with standard triple therapy, which is currently the standard first-line regimen for H. pylori infection, has decreased below the optimum level. The major cause of eradication failure is increased antibiotic resistance. Sequential, concurrent, and hybrid therapies that include clarithromycin produce higher eradication rates than conventional standard triple therapy. However, the effectiveness of these treatments is limited in regions where the resistance rate to various antibiotics is high. Bismuth quadruple therapy is another alternative therapy, but again the eradication rate is not sufficiently high. Tailored therapy based on individual characteristics, including antibiotic susceptibility, may be ideal, but there are several limitations for clinical application and further research is needed. New potassium-competitive acid blocker-based therapies could emerge as effective alternatives in the near future. A consensus is needed to establish a strategy for applying new eradication therapies in Korea.
Ha, Eun Sil;Kim, Hye Ok;Lee, Kyoung Ju;Lee, Eun Joo;Hur, Gyu Young;Jung, Ki Hwan;Lee, Sung Yong;Kim, Je Hyeong;Lee, Sang Yeub;Shin, Chol;Shim, Jae Jeong;Kang, Kyung Ho;Yoo, Se Hwa;In, Kwang Ho
Tuberculosis and Respiratory Diseases
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v.67
no.6
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pp.506-511
/
2009
Background: The smoking prevalence in asthma patients are similar to those in the general population. Asthma and active cigarette smoking can interact to create more severe symptoms, an accelerated decline in lung function and impaired therapeutic responses. Accordingly, asthmatics with a history of smoking were examined to define the clinical characteristics and lung function of smoking asthmatics. Methods: The medical records of 142 asthmatics with a known smoking history were reviewed. The patients were divided into three groups according to their smoking history - current smokers, former smokers and non-smokers. The clinical characteristics, lung function, and annual declines of the forced expiratory volume in one second ($FEV_1$) were compared. Results: Fifty-three of the 142 patients (37%) were current smokers, 24 were former smokers (17%) and 65 were non-smokers (45%). The patients with a hospital admission history during the previous year included 16 current smokers (30%), 4 former smokers (17%) and 7 non-smokers (11%) (p=0.02). The mean $FEV_1$ (% predicted) was 76.8${\pm}$19.8%, 71.6${\pm}$21.1% and 87.9${\pm}$18.7% for current smokers, former smokers and non-smokers, respectively (p< 0.001). The $FEV_1$/forced vital capacity (FVC) (ratio, %) values were 63.6${\pm}$12.6%, 59.3${\pm}$14.9% and 72.1${\pm}$11.8% in current smokers, former smokers and non-smokers, respectively (p<0.001). The corresponding mean values for the individual $FEV_1$ slopes were not significant (p=0.33). Conclusion: Asthmatic smokers demonstrated higher hospital admission rates and lower lung function. These findings suggest that the smoking history is an important predictor of a poor clinical outcome in asthma patients.
Today's health care environment is rapidly changing and nurse administrators' leadership styles need to identify in nursing organization to achieve organizational objectives. By Bass(1985), transformational leadership stimulates the subordinates to be creative and achieve organizational objectives and is related to job satisfaction, job involvement, productivity, and organizational commitment. Transformational leadership process consists of charisma, intellectual stimulation, individual consideration. The purpose of this study was to identify the effect of transformational leadership and personal characteries on nurses' job involvement. The subjects for this study consisted of 594 nurses from 8 University Hospitals and General Hospitals. The data were collected by personal characteristics scale, transformational leadership scale, and job involvement scale. The factor analysis, Cronbach's alpha analysis, Pearson correlation analysis, multiple regression analysis and hierarchical multiple regression analysis were used for the statistical method. The results of this study were found that (1) charisma dimension of transformational leadership has positive influence on nurses' job involvement ; but another two dimensions (intellectual stimulation and individualized consideration) did not showed significant effect on job involvement (2) nurses' personal characteristic (internal locus of control) moderated the effect of transformational leadership on job involvement.
This paper investigates the change of structural characteristics of steel cable-stayed bridges after cable failure. Cables, considered as the intermediate supports of cable-stayed bridges, can break or fail for several reasons, such as fire, direct vehicle clash accident, extreme weather conditions, and fatigue of cable or anchorage. Also, the replacement of cables can cause temporary disconnection. Because of the structural characteristics with various geometric nonlinearities of cable-stayed bridges, cable failure may cause significant change to the structural state and ultimate behavior. Until now, the characteristics of structural behavior after cable failure have rarely been studied. In this study, rational cable failure analysis is suggested to trace the new equilibrium with structural configuration after the cable failure. Also, the sequence of ultimate analysis for the structure that suffers cable failure is suggested, to study the change of ultimate behavior and load carrying capacity under specific live load conditions. Using these analysis methods, the statical behavior after individual cable failure is studied based on the change of structural configuration, and distribution of internal forces. Also, the change of the ultimate behavior and load carrying capacity under specific live load conditions is investigated, using the proposed analysis method. According to the study, significant change of the statical behavior and ultimate capacity occurs although just one cable fails.
Journal of the Korean Society of Clothing and Textiles
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v.47
no.3
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pp.459-474
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2023
Contemporary fashion criticism tends to rely solely on the established art criticism process without consideration of the distinctive characteristics of fashion. Thus, this study aims to reveal the unique roles and characteristics of fashion criticism by recognizing it as an independent field in contemporary art with its own social significance. This study will first apply traditional art criticism models to analyze and explore contemporary fashion criticism's empirical content before uncovering the uniqueness of contemporary fashion criticism by content analysis. Contemporary fashion criticism discusses not just physical objects but various topics and ideas, as well. Accordingly, the existing criticism model was modified in this study to fit contemporary fashion criticism and organized into five stages: description of historical fashion, form description, external evaluation, interpretation, and internal evaluation. Commerciality, the human body, coordination, the critic's individuality, trends, and fashion-related persons were identified as key factors of contemporary fashion criticism's uniqueness. In conclusion, rather than build a single contemporary fashion model, this study found it more effective to create individual fashion criticism models suitable for detailed fields, as these enable the discussion of multifaceted topics in the fashion field. This study is expected to serve a meaningful guide for the fashion discourses.
Kim, Jong-Chul;Jang, Sea-Il;Son, Min-Il;Kim, Tae-Ok
Applied Chemistry for Engineering
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v.8
no.5
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pp.816-821
/
1997
The hydrodynamics and the liquid flow characteristics were investigated in an internal circulation airlift reactor with a single nozzle as a gas distributor. In an air-water system, the gas holdup in the individual flow zone and the impulse-response curve of tracer were measured at various gas velocities and reactor heights. Experimental results showed that for the higher gas velocity(>about 8 cm/s), the flow behavior of bubbles in the riser was turbulent flow due to strong bubble coalescences and the axial height of dispersion zone of large bubbles having uniform sizes in the downcomer was decreased with increasing gas velocity. And mean gas holdups in the individual flow zone and the reactor were increased with increasing gas velocities and were decreased with increasing heights of the top section of the reactor and it was decreased with increasing the height of the top section and gas velocity. Flow characteristics of liquid in the riser and the downcomer was tend to access to plug flow and the overall flow behavior of liquid was mainly varied with the size of the top section which it was assumed to be perfect mixing zone. In these conditions, liquid circulation velocities were increased with increasing gas velocities and they were higher than those by using other gas distributors.
Gas and liquid flow characteristics were investigated in an internal circulation airlift reactor using a single nozzle for a gas distributor. In three reactors with different diameters of the downcomer and heights of the riser, the gas holdup in the individual flow zone and the impulseresponse curve of tracer for an air-water system were measured for various gas velocities and reactor heights. Experimental results showed that the flow behavior of bubbles in the riser was the slug flow due to strong coalescences of bubbles and that the bubble flow pattern in the downcomer was the transition bubble flow for the smaller diameter of the downcomer, however, it was the homogeneous bubble flow for the larger one. And mean gas holdups in the individual flow zone and the reactor were greatly increased with decreasing the diameter of the downcomer for the equal ratio of height of the top section to that of the riser. Also, the mixing time was much effected by the height of the top section of reactor and for the equal ratio of height of top section to that of the riser, it was increased with increasing the diameter of the downcomer and the height of the riser. Flow characteristics of liquid were mainly varied with the bubble flow pattern in the downcomer and the size of the top section of reactor. And circulation velocities of liquid in the riser were increased with increasing gas velocities and the size of the top section of reactor, and for the equal ratio of height of top section to that of the riser, they were increased with increasing the diameter of the downcomer and the height of the riser.
The purpose of this is to investigate the relation between Graffiti techniques and the contemporary dress. Graffiti is the internal expression of human potential desires which is composed of informative signs. As Graffiti have become the cross-cultural condition under the Hiphop culture, it makes the meaningless space into the characteristic space, and proposes the identities of graffiti ‘writes’. In the contemporary dress, Graffiti look has become means of communication and playfulness. Through the external forms like icon, index, and symbol, graffiti look expresses individual, social, and political identities, and aesthetic values of satirement and playfulness. It would be define graffiti look as postmodern characteristics, as it wee, which has collapsed between the mainstream, and anti-mainstream, and it contributes to spread streetstyle to catwalk.
Background: There is very limited data present on smoking cessation rates in outpatient departments of pulmonology. In this study, we aimed to investigate the effectiveness of a brief smoking cessation intervention program in an outpatient department of pulmonology and identify predictors of smoking cessation failure. Methods: After a brief recommendation of smoking cessation from pulmonologists, smokers willing to quit smoking were given individual counseling and supplement drugs. Fifty smokers were included in this study and baseline characteristics, smoking history and success rate were reviewed at 3 months. Results: The mean age of the patients was $58.3{\pm}14.6$ years and the total group of patients included 3 women. The rate of smoking cessation success was 74% at 3 months, and there were no differences in age, spirometric indexes and associated diseases between the smoking cessation success and failure group. The rate of supplement drug usage was not different in both groups either. However, body weight, mean number of cigarette usage per day and nicotine dependence scores in the failure group were significantly higher than in the success group. In multivariate analysis, body weight and mean number of cigarette usage per day were significant. Two smokers with a depressive disorder failed the smoking cessation. Conclusion: A smoking cessation intervention program in the outpatient department of pulmonology showed a favorable success rate. More intensive interventions are needed to unfavorable groups which include the obese and heavy smokers.
Park, Byung Hoon;Park, Moo Suk;Jung, Woo Young;Byun, Min Kwang;Park, Seon Cheol;Shin, Sang Yun;Jeon, Han Ho;Jung, Kyung Soo;Moon, Ji Ae;Kim, Se Kyu;Chang, Joon;Kim, Sung Kyu;Ahn, Song Vogue;Oh, Yeon-Mok;Lee, Sang Do;Kim, Young Sam
Tuberculosis and Respiratory Diseases
/
v.63
no.5
/
pp.405-411
/
2007
Background: The objective of this study was to evaluate the clinical applicability of the repeatability criteria recommended by the American Thoracic Society/European Respiratory Society (ATS/ERS) spirometry guidelines and to determine which factors affect the repeatability of spirometry in Korean adults. Methods: We reviewed the spirometry data of 4,663 Korean adults from the Korean National Health and Nutritional Examination Survey (KNHANES) Chronic Obstructive Pulmonary Disease Cohort (COPD cohort) and the Community-based Cohort Study VI-Fishing village/Islands (community cohort). We measured the anthropometric factors and differences between the highest and second-highest FVC (dFVC) and $FEV_1$ ($dFEV_1$) from prebronchodilator spirometry. Analyses included the distribution of dFVC and $dFEV_1$, comparison of the values meeting the 1994 ATS repeatability criteria with the values meeting the 2005 ATS/ERS repeatability criteria, and the performance of linear regression for evaluating the influence of subject characteristics and the change of criteria on the spiro-metric variability. Results: About 95% of subjects were able to reproduce FVC and $FEV_1$ within 150 ml. The KNHANES based on the 1994 ATS guidelines showed poorer repeatability than the COPD cohort and community cohort based on the 2005 ATS/ERS guidelines. Demographic and anthropometric factors had little effect on repeatability, explaining only 0.5 to 3%. Conclusion: We conclude that the new spirometry repeatability criteria recommended by the 2005 ATS/ERS guidelines is also applicable to Korean adults. The repeatability of spirometry depends little on individual characteristics when an experienced technician performs testing. Therefore, we suggest that sustained efforts for public awareness of new repeatability criteria, quality control of spirograms, and education of personnel are needed for reliable spirometric results.
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