• Title/Summary/Keyword: Indirect Selection

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Comparison of Average Glandular Dose in Screen-Film and Digital Mammography Using Breast Tissue-Equivalent Phantom (유방조직등가 팬텀을 이용한 Screen-Film과 Digital Mammography에서의 평균 유선선량)

  • Shin, Gwi-Soon;Kim, Jung-Min;Kim, You-Hyun;Choi, Jong-Hak;Kim, Chang-Kyun
    • Journal of radiological science and technology
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    • v.30 no.1
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    • pp.13-23
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    • 2007
  • In recent years, mammography system is changed rapidly from conventional screen-film system to digital system for application to screening and diagnosis. Digital mammography system provides several advantages over screen-film mammography system. According to the information provided by the manufacturer, digital mammography system offers radiation dose reduction in comparison with screen-film mammography system, because of digital detector, particularly direct digital detector has higher x-ray absorption efficiency than screen-film combination or imaging plate(IP). We measured average glandular doses(AGD) in screen-film mammography(SFM) system with slow screen-film combination, computed mammography(CM) system, indirect digital mammography(IDM) system and direct digital mammography(DDM) system using brest tissue-equivalent phantom(glandularity 30%, 50% and 70%). The results were shown as follows : AGD values for DDM system were highest than those for other systems. Although automatic exposure control(AEC) mode was selected, the curve of the AGD values against thickness or glandularity increased significantly for the SFM system with the uniform target/filter(Mo/Mo) combination. Therefore, the AGD values for the high energy examinations were highest in the SFM system, and those for the low energy examinations were highest in the DDM system. But the curve of the AGD values against thickness and glandularity increased gently for CM system with the automatic selection of the target/filter combination (from Mo/Mo to Mo/Rh or from Mo/Rh to Rh/Rh), and the AGD values were lowest. Consequently, the parameters in mammography for each exposure besides detection efficiency play an important role in oder to estimate a patient radiation dose.

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Development of Algorithm in Analysis of Single Trait Animal Model for Genetic Evaluation of Hanwoo (단형질 개체모형을 이용한 한우 육종가 추정프로그램 개발)

  • Koo, Yangmo;Kim, Jungil;Song, Chieun;Lee, Kihwan;Shin, Jaeyoung;Jang, Hyungi;Choi, Taejeong;Kim, Sidong;Park, Byoungho;Cho, Kwanghyun;Lee, Seungsoo;Choy, Yunho;Kim, Byeongwoo;Lee, Junggyu;Song, Hoon
    • Journal of Animal Science and Technology
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    • v.55 no.5
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    • pp.359-365
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    • 2013
  • Estimate breeding value can be used as single trait animal model was developed directly using the Fortran language program. The program is based on data computed by using the indirect method repeatedly. The program develops a common algorithm and imprves efficiency. Algorithm efficiency was compared between the two programs. Estimated using the solution is easy to farm and brand the service, pedigree data base was associated with the development of an improved system. The existing program that uses the single trait animal model and the comparative analysis of efficiency is weak because the estimation of the solution and the conventional algorithm programmed through regular formulation involve many repetition; therefore, the newly developed algorithm was conducted to improve speed by reducing the repetition. Single trait animal model was used to analyze Gauss-Seidel iteration method, and the aforesaid two algorithms were compared thorough the mixed model equation which is used the most commonly in estimating the current breeding value by applying the procedures such as the preparation of information necessary for modelling, removal of duplicative data, verifying the parent information of based population in the pedigree data, and assigning sequential numbers, etc. The existing conventional algorithm is the method for reading and recording the data by utilizing the successive repetitive sentences, while new algorithm is the method for directly generating the left hand side for estimation based on effect. Two programs were developed to ensure the accurate evaluation. BLUPF90 and MTDFREML were compared using the estimated solution. In relation to the pearson and spearman correlation, the estimated breeding value correlation coefficients were highest among all traits over 99.5%. Depending on the breeding value of the high correlation in Model I and Model II, accurate evaluation can be found. The number of iteration to convergence was 2,568 in Model I and 1,038 in Model II. The speed of solving was 256.008 seconds in Model I and 235.729 seconds in Model II. Model II had a speed of approximately 10% more than Model I. Therefore, it is considered to be much more effective to analyze large data through the improved algorithm than the existing method. If the corresponding program is systemized and utilized for the consulting of farm and industrial services, it would make contribution to the early selection of individual, shorten the generation, and cultivation of superior groups, and help develop the Hanwoo industry further through the improvement of breeding value based enhancement, ultimately paving the way for the country to evolve into an advanced livestock country.

The Welfare Investment of the National Pension Funds: Its Necessity and Policy Development (국민연금기금의 복지사업 당위성과 정책방향 연구)

  • Kim, Jin-Soo
    • Korean Journal of Social Welfare
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    • v.58 no.3
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    • pp.295-312
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    • 2006
  • The use of the national pension funds to welfare has been criticized due to its low profitability, with concern about financial instability and the lack of funds. Despite the small amount of the funds employed to the welfare, therefore, it has been decreasing so far. It is resulted from the fact that the use of funds to the welfare sector failed to provide its valid reasons, and take the policy direction firmly. There are three main logical reasons for the welfare investment of national pension funds: Firstly, no state is capable to take the full responsibility for the entire social welfare, and therefore, the funds can be used for social welfare. Secondly, the funded system, contrasted with the case of pay-as-you-go system, has inevitably caused discriminations to the present elderly through excluding them institutionally from pension participation. At last, so as to its selective system, the minimum contribution period of 10 years brings about the equity problem between the people who can afford it and the people who hardly can. Therefore, investing a proportion of funds to the welfare is entirely reasonable in that it can alleviate the discriminations to the present elderly generation and the marginal participants, rather than to meet their social welfare needs. With regard to the policy decision, the profitability of the investment, and the choice of the welfare work, on the other hand, the policy direction should be given a sufficient consideration of a various policy factors such as the necessity of social consensus, independence of the welfare work in relations with other national welfare work, policy identity to judge whether the work is worth long-run or short-run, and the reliance of direct-operated work and indirect-operated work. As a result of all these efforts above mentioned, an investment to the welfare of the national pension funds could be vitalized, and gain public confidence.

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A Conjoint Analysis of Online Information Privacy Concerns: A case in Korea (온라인 프라이버시 침해 우려에 관한 컨조인트 분석 : 한국에서의 사례)

  • Choi, Mi-Young;Lee, Sang-Yong Tom
    • Asia pacific journal of information systems
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    • v.18 no.3
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    • pp.45-65
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    • 2008
  • The rapid growth of the Internet has increased the amount of transmission of personally identifiable information. At the same time, with new Internet related technologies, organizations are trying to collect and access more personal information than before, which in turn makes individuals concern more about their information privacy. For their successful businesses, organizations have tried to alleviate these concerns in two ways: (1) by offering privacy policies that promise certain level of privacy protection; (2) by offering benefits such as financial gains or convenience. In this paper, we interpret these actions in the context of the information processing theory of motivation. This paper follows Hann et al.(2007)'s methods to analyze Internet users privacy concerns in Korea and tries to compare the findings. Our research objectives are as follows: First, we analyze privacy concern mitigation strategies in the framework of the expectancy theory of motivation. Subsequently, we show how the expectancy theory based framework is linked o the conjoint analysis. We empirically validate the predictions that the means to mitigate privacy concerns are associated with positive valences resulting in an increase in motivational score. In order to accommodate real-life contexts, we investigate these means in trade-off situation, where an organization may only be able to offer partially complete privacy protection and/or promotions and/or convenience, While privacy protection (secondary use, improper access) are associated with positive valences, we also find that financial gains can significantly increase the individuals' motivational score of a website in Korea. One important implication of this empirical analysis is that organizations may possess means to actively manage the privacy concerns of Internet users. Our findings show that privacy policies are valued by users in Korea just as in the US or Singapore. Hence, organizations can capitalize on this, by stating their privacy policy more prominently. Also organizations would better think of strategies or means that may increase online users' willingness to provide personal information. Since financial incentives also significantly increase the individuals' motivational score of website participation, we can quantify the value of website privacy protection in terms of monetary gains. We find that Korean Internet users value the total privacy protection (protection against errors, improper access, and secondary use of personal information) as worthy as KW 25,550, which is about US 28. Having done this conjoint analysis, we next adopt cluster analysis methodology. We identify two distinct segments of Korea's internet users-privacy guardians and information sellers, and convenience seekers. The immediate implication of our study is that firms with online presence must differentiate their services to serve these distinct segments to best meet the needs of segments with differing trade-offs between money and privacy concerns. Information sellers are distinguished from privacy guardians by prior experience of information provision, To the extent that businesses cannot observe an individual's prior experience, they must use indirect methods to induce segmentation by self-selection as suggested in classic economics literature of price discrimination, Businesses could use monetary rewards to attract information sellers to provide personal information. One step forward from the societal trends that emphasize the need of legal protection of information privacy, our study wants to encourage organizations and related authorities to have the viewpoints to consider both importance of privacy protection and the necessity of information trade for the growth of e-commerce.

Analysis of Lodging Related Characteristics in Rice Plants (벼 도복에 관여하는 형질 분석)

  • 임준택;이홍재;조광석;송동석
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.37 no.1
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    • pp.78-85
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    • 1992
  • This experiment was carried out to investigate the heritabilities, phenotypic correlation, genetic correlation and path-coefficients for desirable characters on the lodging related traits. Characters, that had high relation degree with field lodging degree, were rice-straw length, Wl /P, W/I, Wl /d, L, Wl / A, W/l, P, W $s^2$/ $l^4$ etc. Breaking strength appear negative correlation having an intention to field lodging. The second inertia moment of culm diameter trunk (branch), cross section area, rice-straw thickness and trunk cross section didn't appear negative coefficient with field lodging. It is considered that rice-straw length, leaf dry weight and lodging index, because of high heritability, become selection index of characters for breeding. In direct, indirect effect, and right rice-straw wall thickness appear largest( $P_{7y}$=0.6904), the next is the order of leaf dry weight( $P_{3y}$=0.2848), root dry weight ( $P_{1y}$=0.2658), culm diameter ( $P_{6y}$=-0.2280), and negative relation appear the order of rice-straw length ( $P_{5y}$=-0.9640) and stem dry weight( $P_{2y}$=-0.7072), therefore, the smaller culm length and stem dry weight, the stronger to lodging. to lodging.

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The Characterization of Fish Communities in Urban Streams of the Busan Metropolitan City and Suggestions of Stream Restoration (부산시 도시하천의 어류군집과 하천복원을 위한 제안)

  • Yoon, Ju-Duk;Jang, Min-Ho;Oh, Dong-Ha;Joo, Gea-Jae
    • Korean Journal of Ecology and Environment
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    • v.40 no.2
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    • pp.303-317
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    • 2007
  • The fish community of small freshwater ecosystems gets easily disturbed by direct or indirect human induced disturbances during the period of urbanization. Urbanization is one of factors that generate changes in stream and influences fish fauna in developed countries. This study was conducted in Busan Metropolitan City from 2001 to 2004. In order to investigate the fish community, the city was divided into 3 parts, eastern, central and western. A total of 3,206 individuals of 46 species from 19 families were collected from 55 sites. The dominant species was Rhynchocypris oxycephalus, whereas Zacco temminckii was the subdominant species. Cluster analysis was conducted using primary freshwater fish species collected from each stream. As a result of the analysis, study sites were well differentiated into 3 parts. Two species of Z. temminckii and R. oxycephalus represented the upper part of the stream and Carassius cuvieri, Acheilognathus rhombeus, Hemiculter eigenmanni and Micropterus salmoides represented the middle and lower parts of the stream. When compared with previous studies, fish community of the eastern part of the Busan city where urbanization is in progress, showed similar patterns to the central part. At the time of the habitat restoration of fish fauna in stream, appropriate selection of fish species should be made through analysis of stream character and biogeographic distribution of fish, and long-term monitoring is also needed for sustaining the management of fish fauna.

Comparison of structure modeling with perceived service quality, reason of selection, satisfaction and loyalty of consumers by type of driving range (골프연습장 유형에 따른 서비스품질 및 선택이유와 고객만족, 충성도의 구조모형 비교)

  • Shin, Min-Chul;Park, Keun;Ka, Kyung-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.6
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    • pp.3490-3498
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    • 2014
  • This study examined the relationship among service quality perceived by consumers according to the types of driving ranges(I: indoor and outdoor), market segmentation, the reason for choice of the driving range, customer satisfaction and loyalty and analyze their causal relationship. To reach this goal, this study conducted a questionnaire research for consumers of driving ranges by dividing it into the indoor and outdoor ranges. The quest-factor analysis(SPSSWIN Ver 13.0), the confirmatory factor analysis and the structural equation modeling method (AMOS 6.0) were used to analyze the data collected for this study. Based on the findings of this study, the following conclusions were drawn: The reason for the choice in both indoor driving and outdoor driving had no direct influence on the customer loyalty, but it had an indirect influence on the customer loyalty through customer satisfaction and service expectation. In addition, the service expectation had a direct influence on the customer loyalty in both indoor driving and outdoor driving. Therefore, the customer satisfaction in both indoor driving and outdoor driving serve as a significant mediating variable to reinforce the relationship between the service quality and customer loyalty.

Prediction Model of Suicidal Ideation in Elderly Men Living Alone Based on Ecological System Theory (생태학적 체계이론에 기반한 남자독거노인의 자살생각 예측모형)

  • Hong, Si Myung
    • Journal of agricultural medicine and community health
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    • v.42 no.2
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    • pp.57-68
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    • 2017
  • Objectives: This study was performed to build the predictive model of suicidal ideation of elderly men living alone. Methods: As for the subject, 251 subjects suitable for the selection criteria were selected among elderly men living alone above 65 years old in one region in Gyeongnam and three regions in Gyeongbuk. The data were collected via questionnaires and analyzed using SPSS version 20.0 and Amos version 18.0. Results: The goodness-of-fit test result of hypothetical model were suitable for recommended level: ${\chi}^2/df=1.47$, RMR=.04, GFI=.92, AGFI=.90, CFI=.95, IFI=.95, RMSEA=.04. Self-esteem, individual coping, family cohesion, social support, social activity, and depression explained 55% of the model of suicidal ideation. The most influential direct factor of suicidal ideation was self-esteem, and social isolation was the most influential indirect influence on suicidal ideation. Conclusion: To sum up the above results, if we promote the researched variables of self-esteem, family cohesion, social activity, individual coping and social support in addition to developing and utilizing an efficient customized suicidal prevention nursing intervention program thereby reducing depression and social isolation, suicidal ideation of elderly men living alone would be prevented.

Terminal Protein-specific scFv Production by Phage Display (Phage Display 방법을 이용한 B형 간염 바이러스의 Terminal Protein 특이 scFv 항체 생산)

  • Lee, Myung-Shin;Kwon, Myung-Hee;Park, Sun;Shin, Ho-Joon;Kim, Hyung-Il
    • IMMUNE NETWORK
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    • v.3 no.2
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    • pp.126-135
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    • 2003
  • Background: One of the important factors in the prognosis of chronic hepatitis B patient is the degree of replication of hepatitis B virus (HBV). It has been known that HBV DNA polymerase plays the essential role in the replication of HBV. HBV DNA polymerase is composed of four domains, TP (Terminal protein), spacer, RT (Reverse transcriptase) and RNaseH. Among these domains, tyrosine, the $65^{th}$ residue of TP is an important residue in protein-priming reaction that initiates reverse transcription. If monoclonal antibody that recognizes around tyrosine residue were selected, it could be applied to further study of HBV replication. Methods: To produce TP-specific scFv (single-chain Fv) by phage display, mice were immunized using synthetic TP-peptide contains $57{\sim}80^{th}$ amino acid residues of TP domain. After isolation of mRNA of heavy-variable region ($V_H$) and light-chain variable region ($V_L$) from the spleen of the immunized mouse, DNA of $V_H$ and $V_L$ were obtained by RT-PCR and joined by a DNA linker encoding peptide (Gly4Ser)3 as a scFv DNA fragments. ScFv DNA fragments were cloned into a phagemid vector. scFv was expressed in E.coli TG1 as a fusion protein with E tag and phage gIII. To select the scFv that has specific affinity to TP-peptide from the phage-antibody library, we used two cycles of panning and colony lift assay. Results: The TP-peptide-specific scFv was isolated by selection process using TP-peptide as an antigen. Selected scFv had 30 kDa of protein size and its nucleotide sequences were analyzed. Indirect- and competitive-ELISA revealed that the selected scFv specifically recognized both TP-peptide and the HBV DNA polymerase. Conclusion: The scFv that recognizes the TP domain of the HBV DNA polymerase was isolated by phage display.

Further Evidence of Linkage at the tva and tvc Loci in the Layer Lines and a Possibility of Polyallelism at the tvc Locus

  • Ghosh, A.K.;Pani, P.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.5
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    • pp.601-605
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    • 2005
  • Three lines of White Leghorn (WL) chickens (IWJ, IWG and IWC) maintained at Central Avian Research Institute, Izatnagar (UP), were used for chorioallantoic membrane (CAM) and liver tumour (LT) assay. Eleven-day-old embryos of each line were partitioned into three groups and inoculated with 0.2 ml of subgroup A, subgroup C and an equal mixture of subgroup A and C Rous sarcoma virus (RSV). Subgroup virus receptor on the cell surface membrane for subgroup A is coded for by tumour virus a (tva) locus and for subgroup C by tumour virus c (tvc) locus. The random association of the genes at the tva and tvc loci in IWJ and IWC line was assessed and the $x^2$-values for phenotypic classes were found to be significant, indicating the linkage between the tva and tvc loci. The linkage value was estimated to be 0.09 on pooled sex and pooled line basis. On the basis of four subclass tumour phenotypes a 4-allele model was proposed for tva locus having $a^{s1}$, $a^{s2}$, $a^{r1}$ and $a^{r2}$ alleles and the frequencies were calculated as 0.47, 0.13, 0.13 and 0.27 for IWJ line, 0.31, 0.33, 0.14 and 0.22 for IWG line and 0.44, 0.11, 0.21 and 0.24 for IWC line, respectively. Similarly, for tvc locus the frequencies of four alleles i.e. $c^{s1}$, $c^{s2}$, $c^{r1}$ and $c^{r2}$ were calculated as 0.42, 0.20, 0.21 and 0.17 for IWJ line, 0.42, 0.17, 0.27 and 0.14 for IWG line and 0.30, 0.21, 0.16 and 0.33 for IWC line, respectively. The $x^2$-values for all classes of observations were not significant (p>0.05), indicating a good fit to the 4-allele model for the occurrence of 4-subclass tumour phenotypes for tva and tvc loci. On the basis of the 2-allele model both tva and tvc locus carries three genotypes each. But, on the basis of the 4-allele model tva and tvc locus carries 10 genotypes each. The interaction between A-resistance and C-resistance (both CAM and LT death) was ascertained by taking the 10 genotypes of tva locus and 3 genotypes of tvc locus by pooling the lines and partitioning the observations into 3 classes. The $x^2$-values for the genotypic classes of CAM (-) LT (+) and CAM (-) LT (-) phenotypes to mixed virus (A+C) infection were found to be highly significant (p<0.01), indicating increased resistance, which indicates the joint segregation of $a^r$ and $c^r$ genes, suggesting the existence of close linkage between the tva and tvc loci. Therefore, an indirect selection approach using subgroup C viruses can be employed to generate stocks resistant to subgroup A LLV, obviating contamination with the most common agent causing LL in field condition.