• Journal of Yeungnam Medical Science
• /
• v.37 no.2
• /
• pp.73-78
• /
• 2020

Cancer incidence has been increasing steadily and is the leading cause of mortality worldwide. Gastric cancer is still most common malignancy in Korea. Cancer initiation and progression are multistep processes involving various growth factors and their ligands. Among these growth factors, we have studied hepatocyte growth factor (HGF), which is associated with cell proliferation and invasion, leading to cancer and metastasis, especially in gastric cancer. We explored the intercellular communication between HGF and other surface membrane receptors in gastric cancer cell lines. Using complimentary deoxyribonucleic acid microarray technology, we found new genes associated with HGF in the stomach cancer cell lines, NUGC-3 and MKN-28, and identified their function within the HGF pathway. The HGF/N-methyl-N'-nitroso-guanidine human osteosarcoma transforming gene (c-MET) axis interacts with several molecules including E-cadherin, urokinase plasminogen activator, KiSS-1, Jun B, and lipocalin-2. This pathway may affect cell invasion and metastasis or cell apoptosis and is therefore associated with tumorigenesis and metastasis in gastric cancer.

• Journal of Climate Change Research
• /
• v.9 no.4
• /
• pp.407-421
• /
• 2018

In this paper, I analyze the GHG (greenhouse gas) emission factor of the domestic railway transportation sector using the LMDI (Log Mean Divisia Index) methodology. These GHG factors are the emission factor effect, energy intensity effect, transportation intensity effect, and economic activity effect. The analysis period was from 2011 to 2016, and the analysis objects were an intercity railway, wide area railway, and urban railway. The results show that the GHG emission of railway transportation sector decreased during these 6 years. The factors decreasing the GHG emission are the emission factor effect, energy intensity effect, and transportation intensity effect, while the factor increasing the GHG emission is the economic activity effect.

• Journal of the Regional Association of Architectural Institute of Korea
• /
• v.20 no.6
• /
• pp.25-32
• /
• 2018

According to the data released by Korea Occupational Safety & Health Agency, construction workers suffering from falling disaster have been increasing continuously for the last five years, and in fact, small and medium construction companies' falling disaster forms over 97% of all every year. This means that to reduce falling disaster significantly, it is needed to get rid of disaster taking place in small and medium construction companies. Here, this study aims to analyze various causes of falling disaster in small and medium construction companies, examine how those factors are correlated with one another, and suggest how to manage the risk of falling disaster effectively. According to the study results, main factors influencing falling disaster in small and medium construction companies are found as follows: Situational Awareness/Risk Perception, Fatigue/Alertness, Communications, Equipment/Facilities, and Personal Protective Equipment (PPE) in the Direct Level, Management/Supervision, Education/Training, and Planning in the Organizational Level, and Management's Commitment to Safety in the Policy Level.

• Clinical and Experimental Pediatrics
• /
• v.62 no.7
• /
• pp.245-251
• /
• 2019

Hemodynamically significant preterm patent ductus arteriosus (PDA) affects mortality; comorbidities such as necrotizing enterocolitis, intraventricular hemorrhage, and bronchopulmonary dysplasia; and adverse long-term neurodevelopmental outcomes in preterm infants, particularly in very low birth weight infants. However, recent studies have indicated that there is no consensus on the causal relationship between PDA and neonatal outcomes, the benefit of PDA treatment, the factors guiding the need for treatment, and optimal treatment strategies. Such uncertainty has resulted in wide variations in practice for treating preterm PDA between units, regions, and nations. Nowadays, there has been a paradigm shift to more conservative treatment for preterm PDA, and suggestions regarding selective management of preterm PDA considering risk factors and hemodynamic significance are increasing. Neonatologist-performed echocardiography and advances in modalities to assess hemodynamic significance such as biologic markers and near-infrared spectroscopy also help improve the efficacy of selective treatment of preterm PDA.

• Research in Community and Public Health Nursing
• /
• v.30 no.2
• /
• pp.226-233
• /
• 2019

Purpose: Improving productivity in nursing practice is an important issue. This study investigated factors affecting nursing productivity of Korean clinical nurses. Methods: A structured survey tool was used in a cross-sectional design with a convenience sample of 239 nurses working in university hospitals. Stepwise multiple regressions were done to identify influential factors. Results: The level of nursing productivity was at a moderate level (3.3 out of 5). Those nurses who were over 36, married, over master-graduated, regularly employed, on day duty, and with experiences as a charge or head nurse reported better achievements in nursing productivity than the other groups of nurses. All three independent variables, age, and employment status explained 55.4% of the variance in nursing productivity. Conclusion: The leaders and managers of nursing organizations should develop educational programs aimed at increasing nurses' competencies in relation to emotion controls and communication skills, which consequently should improve nursing productivity.

• Korean Public Health Research
• /
• v.44 no.4
• /
• pp.83-85
• /
• 2018

As the main aim of infectious disease epidemiology is to prevent a pathogen transmission, traditional epidemiological studies have focused on the evaluation of individual-level risk factors. But group-level factors as well as individual-level are important in understanding and controlling transmission of infectious diseases, especially sex-transmitted infectious diseases. Multi-level analysis (MLA) is known as a powerful analytical tool for investigating both levels simultaneously. While new cases of HIV/AIDS in Korea are increasing annually, it is urgently needed to establish research system for MLA led by Korea Centers for Disease Control & Prevention.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.16 no.2
• /
• pp.676-691
• /
• 2022

An increasing number of companies in the fashion industry are using AI curation services. The purpose of this study is to investigate perceptions of and intentions to use AI fashion curation services among customers by using text mining. To accomplish this goal, we collected a total of 34,190 online posts from two Korean portals, Naver and Daum. We conducted frequency analysis to identify the most frequently mentioned keywords using Textom. The analysis extracted "various," "good," "many," "right," and "new" at the highest frequency, indicating that consumers had positive perceptions of AI fashion curation services. In addition, we conducted a semantic network analysis with the top-50 most frequently used keywords, classifying customers' perceptions of AI fashion curation services into three groups: shopping, platform, and business profit. We also identified the factors that boost continuous use intentions: usability, usefulness, reliability, enjoyment, and personalization. We conclude this paper by discussing the theoretical and practical implications of these findings.

• Journal of Information Technology Applications and Management
• /
• v.30 no.2
• /
• pp.31-44
• /
• 2023

Family businesses play a significant role in the overall economy of all countries, and the importance and weight of family businesses are increasing in various fields. Many factors are essential for a family business to grow into a long-lived business, that is, a sustainable business, but the most important one is succession. TRUST Lab at Hanyang University studied the importance of factors influencing the succession of the family business from the standpoint of the successor. As a result, it was confirmed that mutual trust is the most crucial factor, and conflict can destroy that trust. Therefore, in this study, we research conflict as a central topic for successful succession, which is the most fundamental reason for family businesses. This study was conducted as a qualitative research case study. By setting criteria suitable for the purpose of the study, we conducted interviews with ten successors who either worked or planned to work in a family-related company. Through this study, conflict management of key players is the most important to achieve a continuous succession of family businesses.

• International conference on construction engineering and project management
• /
• 2009.05a
• /
• pp.1176-1182
• /
• 2009

Due to recession in real estate market, interest of risk analysis is increasing. Feasibility study in the first stage takes a great role in a project. There are not objectified tools which are able to cope with uncertainty of project, and feasibility study based on selected method of determinism does not include liquidity of weight risk. Also, shortage of consideration for subjective and atypical external factors causes inappropriate results. Therefore, this study proposes feasibility study model focused on risk factor influences in construction cost and sales cost. Considering effective level of cost based on objective risk factors and probable weight of risk by this model, real workers are able to bring correct and scientific decisions better than former method based on selective analysis of real estate development.

• International conference on construction engineering and project management
• /
• 2009.05a
• /
• pp.1015-1022
• /
• 2009

Currently, Korean real estate market has experienced cooling down of the business because of the global economic crisis which resulted from the subprime mortgage lending practice. In response, the Korean government has enforced various policies at the base of deregulating real estate speculation, such as increasing Loan to value ratio (LTV) in order to stimulate housing demand and supply. However, these policies seemed to result in deep confusion in the Korean housing market. Furthermore, analysis for housing market forecasting, especially international financial crisis on Korean real estate market, has been partial and fragmentary, therefore comprehensive solution and systematical approach is required to analyze the real estate and real estate financial market including causal nexus between market determining factors. In an integrated point of view, applying the system dynamics modeling, the paper aims at proposing Korean Real Estate and Mortgage market dynamics models based on fundamental principles of housing market determined by supply and demand. We also find the impact of deregulation policies focusing on mortgage loan which is the main factors of policies.