• The Journal of Korean Physical Therapy
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• 제13권3호
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• pp.665-675
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• 2001

The aim of this study was to compare features of muscle atrophy induced by cast fixation. denervation and suspension of rat hindimb. Muscle mass and glycogen of the soleus and plantaris muscles were studied after 3, 7, or 14 days of cast fixation, denervation and suspension. The results as follows: 1. Body weight of rats decreased significantly after 3 days and showed gradually increase after 7 and 14 days of hindlimb cast fixation, denervation and suspension. Particularly hindlimb suspended rats showed a rapid decrease after 3 days in body weight. 2. Relative weight of soleus and plantaris musclcs decreased significantly by hindlimb cast fixation, denervation and suspension, particularly after 7 days. The decrease rate was the lowest in suspended rats. 3. Glycogen content of soleus muscle decreased significantly after 14 days of hindlimb cast fixation, denervation and suspension. Also glycogen content of plantaris muscle decreased significantly after 14 days of hindlimb cast fixation and denervation, but not significantly after hindlimb suspension. These results indicate that suspension of hindlimb muscles causes less atropy than cast fixation or denervation, likely due to maintainment a few activities during hindlimb suspension. We concluded that the decrease in mechanical strains imposed on the muscle during inactivity was the main factor for the development of atrophy. These basic data suggest that some experimental conditions such as electrostimulation or stretching, participate in countermeasure programmes.

• Asian Pacific Journal of Cancer Prevention
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• 제15권18호
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• pp.7875-7878
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• 2014

Background: The aim of this study was to investigate the awareness of breast cancer risk factors among female university students in 24 low, middle income and emerging economy countries. A cross-sectional survey was conducted with 10,242 undergraduate university students (mean age 20.7, SD=2.9) from 25 universities in 24 countries across Asia, Africa and the Americas. Using anonymous questionnaires the awareness of links between breast cancer and heredity, diet, overweight, exercise, alcohol use, smoking and stress was assessed. Results indicated that 35.4% of the women were not aware that any of these risk factors could influence breast cancer, 43.8% were aware of a genetic link, and only 12.5%, 10.9% and 10.6% correctly identified alcohol use, overweight and physical inactivity, respectively, as factors causing breast cancer. Moreover, 13.3% rated dietary fat and 11.5% fibre as influencing breast cancer; both low-fat and high-fibre diets may be weakly protective against breast cancer, and smoking (19.4%) and stress (13.5%), the most commonly chosen breast cancer lifestyle risk factors, have less clear impact on breast cancer. There were marked country differences, e.g., in regards of being aware of genetic causes of breast cancer risk in female students from Ivory Coast, India, Madagascar, Nigeria and Laos below 30% and female students from Pakistan, Singapore, Turkey, Grenada and Philippines 60 or more percent. This study provides insight in the breast cancer risk perception of young women, which can be utilized in breast cancer awareness and prevention programmes.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.7023-7027
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• 2013

To evaluate the relationship between obesity, diet, physical activity and breast cancer in Thai women, we conducted a case control study with 1,130 cases and 1,142 controls. Informed consent was obtained from all participants and a structured questionnaire was performed by trained interviewers to collect information on demographic and anthropometric data, reproductive and medical history, residential history, physical activity and occupation as well as dietary habits. A significant positive association with an increased risk of breast cancer was observed in women body mass index (BMI) of ${\geq}25mg/m^2$ (OR=1.33, 95%CI 1.07-1.65), the risk being higher in postmenopausal women (OR=1.67, 95%CI 1.24-2.25). In addition, underweight BMI at ages 10 and 20 years showed an inverse association in all women (OR=0.70, 95%CI 0.56-0.88 and OR=0.74, 95%CI 0.59-0.93, respectively) and in those with a premenopausal status (OR=0.69, 95%CI 0.51-0.93 and OR=0.76, 95%CI 0.56-0.99, respectively). Regular exercise was associated with a decreased risk of breast cancer (OR=0.78, 95%CI 0.68-0.98). Interestingly, analysis by type of activity revealed significant protective effects for women who reported the highest levels of walking for shopping (OR=0.58, 95%CI 0.38-0.88). High consumption of vegetables and fruit were associated with a decreased risk of breast cancer, while high consumption of animal fat showed an increased risk in postmenopausal women. In conclusion, our results indicate that obesity and high consumption of animal fat are associated with breast cancer risk, particularly in postmenopausal women, while recreational physical activity has protective effects. It seems that primary prevention of breast cancer should be promoted in an integrated manner. Effective strategies need to be identified to engage women in healthy lifestyles.

• 디지털융복합연구
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• 제16권2호
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• pp.251-259
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• 2018

본 연구의 목적은 Framingham risk score (FRS)를 이용하여 연령군에 따른 심혈관질환의 위험요인을 규명하는 것이다. 본 연구는 국민건강영양조사 제 6기(2013-2015) 자료 중 30-74세 남성 5211명의 자료를 분석한 서술적 횡단연이다. 연령을 통제한 회귀분석 결과 심혈관질환은 정상군에 비해 비만군이 2.5배(OR=2.51, 95% CI=2.05-3.07), 신체활동을 하지 않는 군이 1.7배 (OR=1.71, 95% CI=1.39-2.10), 과음하는 군이 1.3배 (OR=1.33, 95% CI=1.09-1.62) 높게 나타났고 식이섬유 섭취량이 적을수록(OR=0.99, 95% CI=0.98-0.99) 심혈관질환 위험이 높은 것으로 나타났다. 특히 비만은 청년 및 중년 남성의 중요한 예측요인으로 분석되어 향후 본 연구결과는 심혈관질환의 잠재적 위험군인 청년 및 중년 남성을 대상으로 체중감소, 신체활동증가와 같은 생활습관을 변화시키는 교육 및 중재 프로그램 개발에 활용될 것이다.

• 대한한방내과학회지
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• 제40권6호
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• pp.1136-1144
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• 2019

Objective: Physical inactivity contributes to mortality rates and is now the fourth most frequent cause of death worldwide. Red ginseng is a medicinal herb that is often used as an ergogenic aid. In this study, red ginseng was administered to rats to test whether it affected their ability to exercise. Methods: Forty-five rats were randomly distributed and divided into five groups: normal (N, n=5), control (C, n=10), the group to which only red ginseng was administered (H, n=10), the group to which only amino acid complex was administered (A, n=10), and the group to which both red ginseng and amino acid complex were administered (HA, n=10). Once a day for three weeks, 333.3 mg/kg body weight per day (b.w./day) of red ginseng and 750 mg/kg b.w./day of amino acid preparation were administered to rats. After three weeks, body weight, swimming time, and the weight of the anterior tibialis muscle of rat were measured. Blood was taken for analysis using the cardiac puncture method. Results: The swimming time of group H (921.3±199.26 sec) showed significant improvement compared to that of group C (798.48±156.37 sec) (p<0.05). Conclusion: Red ginseng has improved swimming time in rat and can be used as an effective ergogenic aid.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2009년도 춘계학술대회 논문집
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• pp.79-80
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• 2009

The local oxidation using an atomic force microscopy (AFM) is useful for Si-base fabrication of nanoscale structures and devices. SiC is a wide band-gap material that has advantages such as high-power, high-temperature and high-frequency in applications, and among several SiC poly types, 4H-SiC is the most attractive poly type due to the high electron mobility. However, the AFM local oxidation of 4H-SiC for fabrication is still difficult, mainly due to the physical hardness and chemical inactivity of SiC. In this paper, we investigated the local oxidation of 4H-SiC surface using an AFM. We fabricated oxide patterns using a contact mode AFM with a Pt/Ir-coated Si tip (N-type, $0.01{\sim}0.025\;{\Omega}cm$) at room temperature, and the relative humidity ranged from 40 to 50%. The height of the fabricated oxide pattern ($1{\sim}3\;nm$) on SiC is similar to that of typically obtained on Si ($10^{15}{\sim}10^{17}\;cm^{-3}$). We perform the 2-D simulation to further analyze the electric field between the tip and the surface. Whereas the simulated electric field on Si surface is constant ($5\;{\times}\;10^7\;V/m$), the electric field on SiC surface increases with increasing the doping concentration from ${\sim}10^{15}$ to ${\sim}10^{17}\;cm^{-3}$. We demonstrated that a specific electric field ($4\;{\times}\;10^7\;V/m$) and a doping concentration (${\sim}10^{17}\;cm^{-3}$) is sufficient to switch on/off the growth of the local oxide on SiC.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.3293-3298
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• 2013

Background: The study investigated the influence of culturally-based health beliefs on engagement in healthy lifestyle behaviour. Specifically, the study compared levels of engagement between Western and Chinese youth in Australia and assessed the extent to which culture-specific attributions about the causes of illness, and health beliefs, predict engagement in healthy lifestyle behaviour. Materials and Methods: Ninety-four Western and 95 Chinese (N=189; Mean Age=20.8 years, SD=3 years) young adults completed an online questionnaire. Predictor variables were cultural health beliefs measured by the Chinese Cultural Views on Health and Illness scale (CCVH, Liang et al., 2008), and illness attributions beliefs measured by the Cause of Illness Questionnaire (CIQ, Armstrong and Swartzman, 1999). Outcomes variables were levels of engagement in healthy lifestyle behaviour. Results: Results indicated that Chinese participants have a significantly lower exercising rate and healthy dietary habits compared to the Western sample. Moreover, Chinese participants were found to believe more strongly than Westerners that cancer was associated with factors measured by the Traditional-Chinese-Model (TCM). Finally, the observed relationship between cultural health beliefs and physical inactivity was mediated by attributions of illness, in particular to the supernatural subscale, with the Sobel Test showing a significant mediation (z=-2.63, p=0.004). Conclusions: Mainstream approaches to encourage healthy lifestyles are unlikely to be effective when educating Chinese youth. Instead, health promotion programs should attempt to address the illness attribution beliefs and educate Chinese youth about the role of diet and exercise in prevention of diseases such as cancer.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5207-5212
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• 2013

Background: Physical activity has been found to play a role in cancer prevention. The purpose of this matched case-control study was to investigate the association between physical activity levels, water intake, constipation and colorectal cancer (CRC). Materials and Methods: Two hundred and thirty-two patients diagnosed with CRC (125 male, 107 female) were enrolled in this case-control study. Cases were matched to 271 population controls (137 male, 134 female). Results: Drinking more than 4 cups of water daily decreased the risk of CRC by 33-42%; however, this effect was non-significant. Having constipation was found to be a significant risk factor for developing CRC with an OR=6.284 (95%CI=2.741-14.40). With reference to sedentary behavior, minimum activity (600-3000 Metabolic Equivalents Task (MET)) had 43% protection against CRC and the level of Health Enhancing Physical Activity OR was 0.58 (at 95%CI; 0.37-0.92). A significant negative association was found between CRC and physical activity levels expressed as both METs and MET-hours/week (p for trend=0.017 and 0.03, respectively). Among females, a significant trend of reduction in CRC by 62% was observed with increasing the level of physical activity expressed in MET (p for trend=0.04). Conclusions: The risk of CRC may be reduced by adopting a healthy lifestyle and practicing physically activity regularly, especially among females. Consuming adequate amounts of water and healthy bowel motility could also reduce the risk of CRC.

• 한국국방경영분석학회지
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• 제32권1호
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• pp.13-35
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• 2006

국가안보와 산업경쟁력 강화를 동시에 향상시킬 수 있는 민 군겸용기술사업은 효율성 부족과 추진실적 저조로 새로운 개선방안이 필요한 시점이다. 본 연구에서는 그 원인을 선진국과 비교 분석하여 각 사업별 문제점 및 개선점을 도출하고, 민군겸용기술사업의 활성화를 위한 세부 사업별 대안을 제시하고자 한다. 먼저, 우리나라의 무기체계와 산업구조의 특성을 고려한 범정부차원의 정책을 수립하고 활성화 프로그램을 계획해야 한다. 이를 근간으로, 겸용기술개발은 기술수준 조사와 연계하여 필요 핵심기술을 선 개발하고, 기술교류 사업은 민간 및 국방 분야의 모든 기술자료를 연계할 수 있는 통합정보 시스템을 구축해야 한다. 또한 사이버 기술거래시장과 국방벤처센터를 활용하여 기술이전사업을 촉진하고, '국가 규격 및 표준정보체계'를 조속히 구축하여 규격통일화 사업을 확대해 나가야 한다.

• 한국산업보건학회지
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• 제27권3호
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• pp.201-209
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• 2017

Objectives: This study was conducted to assess the association between level of physical activity and depressive symptoms among Korean male workers. Methods: A self-administered questionnaire was distributed and anthropometric measurements were conducted with 1,379 male workers during a general health check. From this data, we identified the general characteristics, levels of physical activity(IPAQ), and depressive symptoms(CES-D) of the study population. We conducted univariate logistic regression to verify the variables that affect depressive symptoms and multivariate logistic regression to calculate odds ratios. Results: Among the 1,379 male workers, 43.4% were in the insufficiently active group(IPAQ category 1) and 22.8% were in the depressive symptom group($CES-D{\geq}16$). The odds ratio(OR) for depressive symptoms was statistically higher in the insufficiently active group, workers aged over 30, the shift work group, and the unmarried group. Adjusted for those variables, the ORs for depressive symptoms were found to be 1.45(95% CI=1.25-2.11), 1.15(OR=1.15, 95% CI=1.08-1.99) and 1.75(95% CI=1.48-2.02), for the insufficiently active group, workers aged over 30, and the shift work group, respectively. Conclusions: We found physical inactivity, age, marital status, and shift work to be associated with depressive symptoms among male workers. This study supports the suggestion that physical activity can be helpful to reduce depressive symptoms among workers.