• 한국약용작물학회:학술대회논문집
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• 2011.09a
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• pp.234-235
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• 2011

• Proceedings of the PSK Conference
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• 2001.04a
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• pp.98-98
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• 2001

• Proceedings of the Korean Society of Life Science Conference
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• 2005.04a
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• pp.144-144
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• 2005

• Molecular & Cellular Toxicology
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• v.3 no.4
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• pp.320-325
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• 2007

Promoter hypermethylation of the $p16^{INK4a}$ gene was investigated in 52 sets of samples of tumor tissue and adjacent normal tissue from Korean patients with colorectal cancer, using the proposed modified the Real-time PCR/SYBR Green detection method presented in this study. In normal tissue, 29 of 52 patients (56%) were methylated and in tumor tissue, 23 of 52 patients (44%) were methylated. The 34 cases (65.4%) showed a concordant DNA methylation pattern in both normal tissue and tumor tissue. Analyzing the association between the clinicopathologic features and DNA methylation status of the $p16^{INK4a}$ gene, the DNA methylation status according to by Duke's stage was different while other clinicopathological characteristics, including the age, sex, tumor stage, and histologic type of the patient were not found to be correlated with $p16^{INK4a}$ methylation. With multivariate logistic regression, it was observed that the DNA methylation status of $p16^{INK4a}$ gene in normal tissue was correlated with the DNA methylation status of the $p16^{INK4a}$ gene in tumor tissue (P=0.026). According to a Kaplan-Meier survival analysis, a difference in the survival rate by DNA methylation status was found, but it was not significant.

• Biomedical Science Letters
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• v.11 no.4
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• pp.481-486
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• 2005

This study was performed to define roles of telomerase and apoptosis and their relationships with clinicopathologic characteristics in colorectal cancers. We performed TRAP (Telomeric Repeat Amplification Protoco1)-ELISA assay for telomerase activity and immunohistochemistry of active caspase-3 expression for apoptosis in 35 colorectal cancers. Increased telomerase activity was detected in $71.4\%$ (25/35) and average apoptotic index was 14.6 per 1000 tumor cells. Telomerase activity and caspase 3 expression had no significant association with clinicopathological characteristics, however, increased telomerase activity was more frequently found in progressed colorectal cancers. Although there is no definitive relation, low apoptotic index group was more frequent in cases with increased telomerase activity. These date indicate that telomerase might be involved in progression of colorectal cancers. We suggest that there is a need for further study to define the relationship between telomerase and apoptosis in colorectal cancers.

• Journal of Environmental Science International
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• v.25 no.7
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• pp.973-987
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• 2016

The spatial and temporal variations of $CO_2$ concentrations and radiative forcing (RF) due to $CO_2$ were examined at urban center (Yeon-dong) during 2010-2015 and background sites (Gosan) during 2010-2014 on Jeju Island. The RF at the two sites was estimated based on a simplified expression for calculating RF for the study period. Overall, annual mean $CO_2$ concentrations at the Yeon-dong and Gosan sites have gradually increased, and the concentrations were higher at Yeon-dong (401-422 ppm) than at Gosan (398-404 ppm). The maximum $CO_2$ concentrations at the two sites were observed in winter or spring, followed by fall and summer, with higher concentrations at Yeon-dong. The RF at Yeon-dong (annual mean of up to $0.70W/m^2$ in 2015) was higher than that at Gosan (up to $0.46W/m^2$ in 2014), possibly because of higher $CO_2$ concentrations at Yeon-dong resulting from population growth and human activities (e.g., fossil fuel combustion). The highest monthly mean RFs at Yeon-dong (approximately $0.92W/m^2$) and Gosan ($0.52W/m^2$) were observed in spring 2015 (Yeon-dong) and spring 2013 (Gosan), whereas the lowest RFs (0.17 and $0.31W/m^2$, respectively) in fall 2011 (Yeon-dong) and summer in 2012 (Gosan).

• Journal of the Korean Home Economics Association
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• v.41 no.8
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• pp.33-53
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• 2003

A Study on the color comparison of Korean Saek-dong and Italian futurist fashion It is generally recognized that the color scheme and its characteristics as a product of living culture are strongly reflected in clothing. This study concentrates on the color comparison of Korean Saek-dong which has been used in traditional Korean clothing and Italian futurist fashion which showed dynamic characteristics and brilliant colors. The purpose of this study is to investigate the external format, emotions, functions and meanings of the colors in Korean Saek-dong and Futurist fashion, and to find similarities and differences between them. The results of the study are as follows. The similarities between them are harmony of vivid colors like a rainbow, no-use of black color and expression of rhythm through repeated geometrical shapes. They have been used as festive costumes and have implied meaning of happiness and pleasure. The differences, in the external formats, are as follows. Korean Saek-dong has striped patterns including the color white, and has regular distances among the stripes. But, Futurist fashion includes luminous or fluorescent colors and metallic colors. In addition, it has repeated motifs of geometrical shapes and geometrically divided areas. While Saek-dong expresses Sangsaeng through the conceptual use of color, Futurist fashion shows simultaneity, speed and dynamics through spiritual functions of crossing and inter-penetration. In emotional aspect, Saek-dong expresses pleasure of children's mind and Futurist fashion expresses pleasure of city. In functional aspect, Saek-dons expresses a concept of ceremonial beauty, which is spiritual and symbolizes good auspices, holiness and sorcery. So it is used for ceremonial costume. But, Futurist fashion reflects the harmony of colors created from modem and urban images and shows the willingness and emotion of solving futuristic avant-garde, modernity, dynamics, transformation and bellicosity. So it is used for daywear. While Saek-dong represents succession of tradition, Futurist fashion represents resistance of tradition in cultural aspects.

• Journal of the Korean association of regional geographers
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• v.16 no.5
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• pp.441-456
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• 2010

While the Dong Hae was originally named for the point of the compass, it became a proper noun containing knowledge on the long history. The Dong Hae has played host to a number of historic events and cultural meanings and is a geographical space in the nature. This study examined the geographical cognition of ancestors about the Dong Hae among the historic and cultural meanings of Dong Hae and a variety of figurations described in literature. Intellectuals of the Joseon period identified the global geography on a higher level an recognized the geography and topography of the land in the structure that they identified. In this aspect, Mt. Baekdu, one of two mountains which dominated the world, ruled the geography of Liaodong field, the Korean peninsula and Japnn. Historical geographers mentioned the Dong Hac whenever discussing Mt. Baekdu and Baekdudaegan (Great Range) from long ago. Baekdudaegan and the Dong Hae are the complete symbol of national territory with great size, depth, height, width, dignity and magnanimity. The cultural figurations of the Dong Hae were classified into four categories. In Korean literature, the Dong Hae strengthened the spirits of those who lived in the Korean peninsula. Second, the Dong Hae was the basis to see through and deliberate the reasons of life and the world. Third, the view of the Dong Hae from Baekdudaegan changed the cognition about the land. Finally, the Dong Hae was where the hard life of people in the fishing villages occurred and a variety of customs and trades were dynamically deployed.

• Proceedings of the KIEE Conference
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• 2006.04b
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• pp.185-187
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• 2006

The line-start permanent magnet synchronous motor has a high efficiency and an advantage in constant speed operation regardless of the effect of load variation. However it is difficult to predict the performance of characteristics accurately, because of the unbalanced starting torque with the initial starting position of the rotor and the generation of a break torque. In this paper the dynamic characteristics of the line-start permanent magnet synchronous motor are described and compared with those of the squirrel-cage induction motor through the simulation to find the characteristics of the permanent magnets and the rotor bars in the line-start permanent magnet synchronous motor.

• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.536-539
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• 2003

A strong constitutive $P_{JH}$ promoter from Bacillus sp. was applied to overexpress the endoxylanase gene in Bacillus subtilis. The expression plasmid, pJHKJ4, was designed to contain the $P_{JH}$ promoter and open reading frame of endoxylanase including its own promoter. The plasmid was introduced into B. subtilis DB431 and the resulting transformant was grown on LB glucose medium. The endoxylanase activity in the culture supernatant reached about 140 unit/ml. The enzyme in the supernatant was efficiently concentrated to 70% by two-step treatments of ammonium sulfate saturation and ultrafiltration. The stabilization of concentrated enzyme solution at different storage temperatures was examined with various stabilizers such as NaCl, $CaCl_2$, sucrose, sorbitol, polyethylene glycol, and Tween-80.