• The Journal of Internal Korean Medicine
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• v.28 no.4
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• pp.727-732
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• 2007

Objectives : This study investigated using National Institutes of Health Strokes Scale in acute and subacute stroke patients and evaluated relativity of pulse pattern to NIHSS. Methods : 104 acute and subacute stroke patients were selected from 4 oriental medical hospitals from April 2007 to May 2007. The patients were admitted to hospital within 1 month after stroke. Pulse feeling diagnosis was done by oriental medical doctor and classified into 7 subtypes. Results : There were significant results statistically between slow/rapid pulse and NIHSS score in the male group; in the female group, there were no significant results statistically but the results showed that slow pulse has lower NIHSS score than rapid pulse. Patients with surging pulse had lower NIHSS score than the other patients. Another pulse pattern had no relativity to NIHSS score.

• Journal of Korean Critical Care Nursing
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• v.13 no.1
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• pp.44-62
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• 2020

Purpose : The purpose of this study was to systematically review the measurement tools that are used to assess the pain of intensive care unit (ICU) patients. Method : In this systematic review, the studies published between 2009 and 2018 were selected based on the PRISMA flow chart. Data sources included MEDLINE, EMBASE, CINAHL, and Cochran. We assessed the quality of pain assessment tools reported in individual studies using Terwee et al.'s the Quality Criteria for Measurement Properties. Results : We reviewed 67 studies and 12 pain assessment tools that included two self-reported, seven observational, and three multifaced tools with observations and physiological indicators. The most frequently used tool was the Critical Care Pain Observation Tool. The Multidimensional Observational Pain Assessment Tool was rated the highest quality. Nine of the ten tools that included observations reported content validity, four reported construct validity and nine reported correlation coefficient. Conclusion : It was found that observational tools are appropriate for assessing pain in ICU patients with limited communication skills. To increase the validity and reliability of pain assessment in ICU patients, further research on the physiological indicators of pain is needed.

• Journal of Pharmacopuncture
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• v.9 no.1
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• pp.59-67
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• 2006

Objectives : This study planed to evaluate effect of oriental medicine therapy treatment method of dyspnea that happen from cancer of the pancreas patient who accompany Multiple metasis Methods : Patient complained dyspnoea during admission into dept. Of internal medicine, college of oriental medicine, Dong-eui Univ, was appealed patient treated by Oriental medicine therapy that is of use Herb Medication and Herbal -acupuncture Treatment being diagnosed in lung asthenia including deficiency of Eum and insufficiency of Gi of the lung(肺虛), the fire due to deficiency(虛火), and loving warfare of symptoms evaluated through VAS (visual analog scales). Results & Conclusion : Patient's difficulty in breathing symptoms took a favorable turn after treatment. This study means that Oriental medicine therapy that is difficulty in breathing symptoms that happen from patient surely has effectiveness.

• Polymer(Korea)
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• v.31 no.5
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• pp.417-421
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• 2007

A successful rapid synthesis of dendritic benzyl chlorides from dendritic benzyl alcohols using methanesulfonyl chloride/$Et_3N$ as activating agents was described. In this method, each dendritic benzyl chloride can be prepared in one pot: no isolation of intermediate mesylated dendrons is required. The key steps in the syntheses of dendritic benzyl chlorides were the mesylation of the hydroxymethyl group followed by the chlorination by in-situ generated triethylammonium chloride.

• Korean Journal of Veterinary Research
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• v.7 no.2
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• pp.56-59
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• 1967

Number of dairy cow patients diagnosed and treated at Hyup Dong Large Animal Clinic during the year, October 1, 1966, through September 30, 1967, were amounted to 1,119 cases and the result of analysis of disease incidence during one year period were as follow: 1. In the etiologic diagnostic categories, diseases cause by infection with lower organism were most productive and 43.3% of all diagnosis involved in this category. 2. In the topographic diagnostic categories, 37.3% of all diagnosis involved the urogenital system and were observed most productive. 3. As a result of each topographic diagnostic categories were subdivided into disease entities, 21.4% of all diagnosis involved the mastitis and this were observed most productive in the miscellaneous disease entities. Next productive disease were indigestion (11.9%), endometritis(11.5%), miscellaneousl ovarian disease(11.1%) and retained placenta(81.1%) chronologicaly.

• Journal of Acupuncture Research
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• v.21 no.2
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• pp.287-300
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• 2004

Objective: The aim of this research was to investigate the effect of acupuncture and the effect of Dong's acupuncture on Bell's palsy. Methods: We measured the facial palsy changes of the patients who were admitted for Bell's palsy in the Oriental Medical hospital of Dongeui medical center from 07-01-2003 to 09-30-2003. Bell's palsy patients were divided into two groups. One group(A group) was treated by acupuncture. The other group(B group) was treated by Dong's acupuncture. The effects of these treatment was evaluated by Yanagihara's unweighted grading system. Results : B group was marked more higher than A group in treatment outcome. we discovered that it is significant differences between two groups after 2 week. Conclusion : These results provided that A group is more effective than B group on. For clearly comparing the Effect of Acupuncture and Dong's Acupuncture on Bell's palsy, it is need more sample's number and more treatment's duration.

• Biomolecules & Therapeutics
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• v.6 no.4
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• pp.395-399
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• 1998

DW2282, (S)- (+)-4-phenyl -1-[N-(4-am mob enzoyl) -indolin-5- sulfonyl]-4,5- dihydro-2-imidazolone hydrochloride, is a novel anticancer agent thought to have an unique mechanism of action on the inhibition of tumor growth. In this study, we estimated in vivo antitumor activities and pharmacokinetics of Dw2282 depending on various vehicles. The inhibition rate of tumor growth was increased by 50, 100 and 200 mg/kg of Dw2282 in a dose-dependent manner. When Dw2282 dissolved in 4 sorts of vehicles was orally single dosed to rats at 50 mg/kg, Cmax of Dw2282 in 0.5% CMC.Na was a half as high as those in PG, PG+CP and PG+CP+DW. When Dw2282 was orally administered to mice for 5 days, antitumor activity of 130 mg/kg suspended in 0.5% CMC.Na was as effective as that of 65 mg/kg dissolved in the rest of vehicles. Taken together, it is thought that antitumor activities of Dw2282 are resulted from the absorption extent of it and related to the vehicle used.

• 한국약용작물학회:학술대회논문집
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• 2012.05a
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• pp.175-176
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• 2012

• Journal of Korean Society for Atmospheric Environment
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• v.5 no.2
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• pp.42-54
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• 1989

This study was carried out to investigate the phenomena of acid precipitation. The pH value, electro conductivity and major anions (sulfate, nitrate and chloride) were measured by automatic acid rain monitor and ion chromatography at 5 points in Seoul area from Jan. to Dec. 1988. 1. The acidity of rainfall was in order winter (4.31) spring (4.77) fall (4.94) summer (5.31). Rainfall with a pH of less than 5.6 was appeared 83.2 percent. 2. The range of the highest appearence frequency rate both at Hannam-dong and Songsu-dong was from pH 4.6 to 5.0 and appeared 30.7 percent and 38.3 percent respectively, Bang-i-dong was 36.3 percent in the ranged from pH 4.1 to 4.5 and Guro and Ssangmun-dong were 26 percent and 30.3 percent in the ranged from pH 5.1 to 5.5 respectively. 3. The sulfate and nitrate ion concentration in earlier rainwater ranged from 0.1 ppm to 50.2 ppm and from 0.01 ppm to 15.8 respectively. The earlier rainwaters were generally more acidic than the after rainwaters. 4. The order of the major anion concentration in rainwater was $SO_4^{2-} > Cl^- > NO_3^-$ and the acidity of it was more effective by sulfate ion than others. The correlation between pH value and anions concentration was shown positive correlationship at Guro-dong and Bang-i-dong and negative correlation at Hannam-dong but not at the other sites.

• Toxicological Research
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• v.14 no.4
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• pp.501-505
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• 1998

The acute toxicity study of combined antibiotic (Cefatrizine / Clavulanic Acid), a formulation consisting of cafatrizine and clavulanic acid in a ratio of 2 : 1, was evaluated in rats. The antibiotic was orally administered with single dose in dose levels up to 5 g/kg (0, 1.25, 2.5, 5 g/kg). Treatment-related effects were limited to soft stool excretion and caecal dilatation, but histologically no morphological changes could be detected in caecum. In hematology, serum-chemistry parameters and histopathology, no drug-related changes were found. The results of the present study indicate that cefatrizine / clavulanic acid has a low toxic potential and the oral $LD_{50}$values exceed 5 g / kg in rats