• 동의생리병리학회지
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• 제33권4호
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• pp.198-206
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• 2019

This study was conducted to evaluate the vasorelaxant effect of DangGuiSu-San and SamHwangSaSim-Tang extract on contracted rabbit carotid artery. To study the effect of DangGuiSu-San and SamHwangSaSim-Tang extract on contracted rabbit carotid arterial strips, arterial strips with intact or damaged endothelium were used for experiment using organ bath. The pre-contracted arterial strips with Phenylephrine(PE) was treated with various concentrations of DangGuiSu-San and SamHwangSaSim-Tang extract(0.01, 0.03, 0.1, 0.3 and $1.0mg/m{\ell}$). To determine the mechanisms of DangGuiSu-San and SamHwangSaSim-Tang-induced vasorelaxant, DangGuiSu-San and SamHwangSaSim-Tang extract were infused into contracted arterial rings which had been pretreated by indomethacin(IM), tetraethylammonium chloride(TEA), $N{\omega}$-nitro-L-arginine ($_L-NNA$), methylene blue(MB). And calcium chloride(Ca) 1 mM was infused into precontracted arterial ring induced by PE after treatment of DangGuiSu-San and SamHwangSaSim-Tang extract in $Ca^{2+}$-free krebs solution. DangGuiSu-San and SamHwangSaSim-Tang extract revealed significant relaxation on PE-induced arterial contraction. DangGuiSu-San and SamHwangSaSim-Tang extract also had an effective relaxation to the intact endothelium arterial ring. SamHwangSaSim-Tang extract on contracted rabbit carotid artery is related with NO-cGMP pathway. Pretreatment of DangGuiSu-San and SamHwangSaSim-Tang extract inhibited the contraction by influx of extracellular $Ca^{2+}$ in contracted arterial ring induced by NE. This study indicated that the relaxation effect of SamHwangSaSim-Tang extract on contracted rabbit carotid artery is related with NO-cGMP pathway. Pretreatment of DangGuiSu-San and SamHwangSaSim-Tang extract inhibited the contraction by influx of extracellular $Ca^{2+}$ in contracted arterial ring induced by NE.

• 대한한의학원전학회지
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• 제12권2호
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• pp.282-292
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• 1999

In oriental medicine Acupuncture treatment is one of the most valuable therapy. Through the acupuncture humen have been healed many diseaes with his own natural therapic power, without medicine or surgery ect. But there have not formed a clear definition on the supplement & eradication(補瀉). I recognised the difference between the original meaning of Young-su(迎隨) mentioned in $\ll$Whang-Je-Nae-Kyung(黃帝內經)$\gg$ and Young-su-Bo-Sa(迎隨補瀉) that are recently used. The results were summerized as follow; 1. In the $\ll$Whang-Je-Nae-Gyung$\gg$, when they give medical teatment, they have totally used all methods of the supplement & eradication(補瀉). Therefore as now divided into respiration, speed, rotation and close-open supplement & eradication(補瀉) have many problomes. And Young-su(迎隨) did not mean the treatement of supplement and eradication which go with or against the flowing of channel energy(經氣). Young-su(迎隨) is not a simple technique of treatment, but is the totall principle of the supplement and eradication. 2. The direction of channel energy(經氣) connected with the O-su point (五輸穴) is from extremities to the trunk of body, therefore the direction of supplement is to the trunk of body and the direction of eradication is to extermities. 3. In the case of using the treatment which go with or against the flowing of channel energy(經氣), in oder to avoid the confusion of term, it must be defined another term. 4. It is necessary that we must define the procedure of supplement & eradication, and the objective indication that ascertain whether the doctor's purposes are really obtained.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5463-5468
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• 2014

MicroRNAs might act as oncogenes or tumor suppressors in cancer. Recent studies have shown that miR-421 is up-regulated in human gastric cancer. Here, we found that miR-421 was over-expressed in gastric cancer tissues and cell lines. Bioinformatics analysis predicted that the caspase-3 gene was a target of miR-421. Caspase-3 was negatively regulated by miR-421 at the post-transcriptional level. Bax and Bcl-2 were also regulated by miR-421. Moreover, tumor necrosis factor receptor-I and -II, death receptors in the apoptosis pathway, were up-regulated by miR-421. The over-expression of miR-421 promoted gastric cancer cell growth and inhibited apoptosis of the BGC-823 gastric cancer cell line. These observations indicate that miR-421 acts as a tumor promoter by targeting the caspase-3 gene and preventing apoptosis of gastric cancer cells through inhibition of caspase-3 expression. These findings contribute to our understanding of the functions of miR-421 in gastric cancer.

• 대한약침학회지
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• 제11권1호
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• pp.189-199
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• 2008

In $\ulcorner$Yingshu(靈樞)$\lrcorner$, $\ulcorner$Sumun(素問)$\lrcorner$ and $\ulcorner$Najing(難經)$\lrcorner$, there are differences in viewing FiveSu-point(五輸穴) and its practical application in treatment. The following conclusions are induced from these different point of views. 1. Fundamental features of FiveSu-point are shown in$\ulcorner$Yingshu(靈樞)$\lrcorner$ 2. In $\ulcorner$Internal classic(內經)$\lrcorner$ and $\ulcorner$Najing(難經)$\lrcorner$, it seems attachment that FiveSu-point is identical to the Five Elements, but there are differences in using the Five Elements sangsyang-sangguk in treatment. 3. There are clear differences between $\ulcorner$Internal classic(內經)$\lrcorner$ and $\ulcorner$Najing(難經)$\lrcorner$ in attachment of FiveSu-point and Fourseasons. Differences are shown in each chapter of $\ulcorner$Yingshu(靈樞)$\lrcorner$. 4. Different application of FiveSu-point's various cases is shown in $\ulcorner$Yingshu(靈樞)$\lrcorner$, $\ulcorner$Sumun(素問)$\lrcorner$ and $\ulcorner$Najing(難經)$\lrcorner$. 5. Different application of FiveSu-point in $\ulcorner$Yingshu(靈樞)$\lrcorner$, $\ulcorner$Sumun(素問)$\lrcorner$ and $\ulcorner$Najing(難經)$\lrcorner$ is due to different historical background.

• 한국도서관정보학회지
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• 제23권
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• pp.405-437
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• 1995

This article aims at bibliographical analysis of the . The summary of this study is as follows: 1) Through the investigation of the related historical records. The author was found as No YiJeom who lived in Kongju at the King JeongJo period. 2) was written about the same traveling of China at same time with Park JeeWon's (YeolHaIlki>. The format of this materials was recorded everyday from leaving to arriving in Hanyang. 3) The result of comparison these two writings, the was described better on the view of traditional Confucianism more than the . 4) According to the study, is a new material to provide in the Korean Studies as Korean literature, history, bibliography etc.

• 한국작물학회지
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• 제48권4호
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• pp.286-291
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• 2003

Monochoria vaginalis is one of the most troublesome resistant weeds in Korean rice culture. Thus, the objectives of this study were to evaluate the response of M. vaginalis resistant to sulfonylurea(SU) herbicides and to determine alternative herbicides for the control of resistant M. vaginalis in direct seeded and transplanted rice culture in Korea. In greenhouse studies, the resistant biotype was 31-, 38-, 3172-, and 7-fold more resistant to ben-sulfuron-methyl, cyclosulfamuron, imazosulfuron, and pyrazosulfuron-ethyl, respectively, than the susceptible biotype, indicating cross-resistance to the SU herbicides used in this study. Non-SU herbicides, butachlor, carfentrazone-ethyl, mefenacet, pretilachlor, pyrazolate, and thiobencarb, several SU herbicide-based mixtures, ethoxysulfuron plus fentrazamide, pyrazosulfuron-ethyl plus pyrazolate plus simetryn, and non-SU herbicide-based mixtures, pyrazolate plus butachlor, pyrazolate plus pretilachlor, simetryn plus molinate, carfentrazone-ethyl plus butachlor, and carfentrazone-ethyl plus thiobencarb can be used to control both the resistant and susceptible biotypes of M. vaginalis when applied before the second leaf stage. In the field experiment, the resistant biotype of M. vaginalis that survived from the paddy fields treated with a SU herbicide-based mixture could effectively be controlled by using mixtures of bentazone plus MCPA, bentazone plus mecoprop-P, and bentazone plus 2,4-D when applied at 2 or 4 main leaves. Our results suggest that the SU-resistant M. vaginalis had not developed multiple resistances to herbicides with different modes of action. In particular, bentazone plus MCPA and bentazone plus mecoprop-P were effective control measures after failure to control resistant M. vaginalis in Korean rice culture.

• Korean Journal of Acupuncture
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• 제18권1호
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• pp.27-63
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• 2001

The phrase 'Gyeong Su' in the twelve gyeong su(經水) indicate twelve lower reaches of rivers and lakes which are located in the center of China. The reason of this chapter called 'twelve gyeong su(經水)' is that the ki(氣) circulation through twelve meridians in the human body is similar to constant flow of twelve lower reaches of rivers and lakes. This chapter is divided into five sub chapters, according to its contents as follows, Chapter 1 deals with the correlation between twelve gyeong su and twelve meridians, Chapter 2 deals with the correlation between universe and human body, Chapter 3 deals with the definite example of the correlation between human body and universe and Um-Yang(陰陽), Chapter 4 deals with most proper acupuncturing depth and remain time of acupuncture according to the theory of man, as a microcosm, is connected with the macrocosm(天人相應) and more or less of moxibustion amount, Chapter 5 deals with acupuncture application according to height, age, body shape of patients.

• 전자공학회논문지
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• 제52권7호
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• pp.33-39
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• 2015

본 연구에서는 SU-8을 절연층으로 사용해 솔루션 공정을 바탕으로 하여 Indium Zinc Oxide(IZO) thin film transistor(TFT)의 안정성을 향상에 대해 연구하였다. 매우 점성이 강하며 negative lithography 용으로 사용되는 SU-8은 기계적, 화학적으로 높은 안정도를 가진다. 그리고 이 SU-8을 사용해 TFT층의 위에 스핀코팅을 사용해 절연막 층을 쌓고 photo lithography를 이용해 patterning을 하였다. SU-8층에 의한 positive bias stress(PBS)에 대한 전기적 특성 향상의 이유를 연구하기 위해 TFT에 X-ray photoelectron spectroscopy(XPS), Fourier transform infrared spectroscopy(FTIR) 분석을 시행하였다. SU-8을 절연층으로 한 TFT는 좋은 전기적 특성을 보였으며, 전류점멸비, 전자이동도, 문턱전압, subthreshold swing이 각각 $10^6$, $6.43cm^2/V{\cdot}s$, 7.1V, 0.88V/dec로 측정되었다. 그리고 3600초 동안 PBS를 가할 시 ${\Delta}V_{th}$는 3.6V로 측정되었다. 그러나 SU-8 층이 없는 경우 ${\Delta}V_{th}$는 7.7V 였다. XPS와 FTIR을 분석한 결과, SU-8 절연층이 TFT의 산소의 흡/탈착을 차단하는 특성에 의해 PBS에 강한 특성을 나타나게 함을 확인하였다.

• 한국항행학회논문지
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• 제20권5호
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• pp.440-445
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• 2016

인지라디오망에서 제한된 스펙트럼 자원을 효율적으로 이용하는 방법으로 PU (primary user)가 사용하지 않는 스펙트럼 홀의 크기를 예측하여 SU (secondary user)가 이용하는 방법이 있다. 본 논문은 SU의 서비스품질을 만족시키기 위하여, SU스펙트럼 홉핑호의 손실확률 (SHDP; spectrum hopping call dropped probability)을 최소화는 적응 호수락제어 기법을 제안한다. 이 방법은 호수락제어, 대역폭예측, 적응대역폭할당으로 구성된다. 예측기법은 스펙트럼홀의 크기뿐만 아니라, SU스펙트럼 홉핑호가 요구하는 대역폭크기를 함께 예측하며, 예약할 수 있는 자원의 크기가 부족할 때는 적응대역폭할당을 이용하여 SU스펙트럼 홉핑호의 손실확률을 최소화시킨다. 예측기법은 위너예측기법을 이용한다. 시뮬레이션을 통하여 제안한 방법의 성능을 기존방법과 비교하고, SHDP를 최소화 할 수 있음을 보인다.

• Journal of Chest Surgery
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• 제51권3호
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• pp.172-179
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• 2018

Background: This study aimed to compare preliminary data on the outcomes of sutureless aortic valve replacement (SU-AVR) with those of aortic valve replacement (AVR). Methods: We conducted a retrospective study of SU-AVR in moderate- to high-risk patients from 2013 to 2016. Matching was performed at a 1:1 ratio using the Society of Thoracic Surgeons predicted risk of mortality score with sex and age. The primary outcome was 30-day mortality. The secondary outcomes were operative outcomes and complications. Results: A total of 277 patients were studied. Ten patients (50% males; median age, 81.5 years) underwent SU-AVR. Postoperative echocardiography showed impressive outcomes in the SU-AVR group. The 30-day mortality was 10% in both groups. In our study, the patients in the SU-AVR group developed postoperative thrombocytopenia. Platelet counts decreased from $225{\times}10^3/{\mu}L$ preoperatively to 94.5, 54.5, and $50.1{\times}10^3/{\mu}L$ on postoperative days 1, 2, and 3, respectively, showing significant differences compared with the AVR group (p=0.04, p=0.16, and p=0.20, respectively). The median amount of platelet transfusion was higher in the AVR group (12.5 vs. 0 units, p=0.052). Conclusion: There was no difference in the 30-day mortality of moderate-to high-risk patients depending on whether they underwent SU-AVR or AVR. Although SU-AVR is associated with favorable cardiopulmonary bypass and cross-clamp times, it may be associated with postoperative thrombocytopenia.