• 제목/요약/키워드: In-su

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Structural Genomic View of Microbial Genomes

  • Moon, Tae-Sung;Lee, Jin-Kak;Han, Won-Seok;Choi, Han-Su;Han, Min-Su;Eom, Ki-Dong;Lee, Min-Kyung;Yoon, Chang-No
    • 한국미생물학회:학술대회논문집
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    • 한국미생물학회 2006년도 International Meeting of the Microbiological Society of Korea
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    • pp.76-79
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    • 2006
  • At present, hundreds of microbial genomes have been sequenced, and hundreds more are currently in the sequencing pipeline. As the amount of genome data is expanding, researchers are much in need of tools that can process huge amount of sequence data. Here, we will discuss about several bioinformatics tools and their applications.

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The 3D-QSAR study of non-peptide bradykinin antagonists by CoMFA

  • Park, Hea-Young;Choi, Su-Young;Lee, Su-Jin;Kam, Yu-Rim
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.186.1-186.1
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    • 2003
  • Bradykinin is an autocoid related to acute and chronic pain and inflammation. The non-peptide bradykinin antagonists are of interest as novel anti-inflammatory therapeutics. Some active compounds such as FR 173657, LF 160687, and bradyzide were reported very recently. In our search for the new bradykinin antagonists, we designed and synthesized the iminodiacetic acid derivatives having two or three amide bonds and lipophilic ring system in each molecule. Liquid phase combinatorial synthesis using the iminodiacetic acid template gave diverse individual compounds rapidly and efficiently on a 10-50 mg scale. (omitted)

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생체의학에 적용 가능한 테이퍼형태의 금속성 마이코로니들 어레이의 개발 (A Development of Tapered Metallic Microneedle Array for Bio-medical Application)

  • 제우성;이정봉;김갑석;김경환;진병욱
    • 마이크로전자및패키징학회지
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    • 제11권2호
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    • pp.59-66
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    • 2004
  • 본 연구에서는 유리기판을 통한 SU-8의 이중층을 후면 노광을 통하여 테이퍼지고 속이 빈 형태의 마이크로니들 배열구조물을 만드는 새로운 방법을 제안하였으며 테이퍼지고 속이 빈 형태의 원형축의 Buckling현상에 관한 해석해를 구하였다. Pyrex 7740을 유리기판으로 사용하고 이중층 구조의 SU-8 막을 후면 노광으로 금형 구조물을 제작하는 공정을 개발하였다. $200\;{\mu}m$ 높이의 SU-8기둥들에서 $4.37{\sim}5^{\circ}$범위의 테이퍼 각도를 $400\;{\mu}m$ 높이의 SU-8기둥에서는 $3.08{\sim}4.48^{\circ}$범위 내의 테이퍼 각을 보여주고 있다. 후면 유체저장소와 가로세로 각각 10개의 테이퍼 형태로 전기도금된 니켈 마이크로니들 어레이를 유리 기판을 통해 이중층 구조의 SU-8막을 후면 노광하고. 니켈을 전기도금 함으로서 실현시켰다. $200\;{\mu}m$$400\;{\mu}m$ 높이의 벽두께 $10{\mu}m-20{\mu}m$ 및 내경 $33.6{\mu}m-101{\mu}m$인 마이크로니들 어레이를 제작하였다. 또한 $400\;{\mu}m$ 높이의 벽두께 $20\;{\mu}m$ 및 내경 $33.6\;{\mu}m$$3.08^{\circ}$의 테이퍼 각 마이크로니들의 임계 버클링힘은 1.8N이었다. 이 해는 차후의 테이퍼 형태의 마이크로니들의 설계시 많은 도움을 주리라 생각한다.

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수신사(修信使)가 본 근대일본풍속(近代日本風俗) - 김기수의 일본풍속인식을 중심으로 - (The late 19th century Japanese folk culture which Korean Embassy experienced - Focused on Japanese folk culture recognition of Ki-Su Kim(金錡秀) -)

  • 전성희;박춘순
    • 한국생활과학회지
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    • 제14권5호
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    • pp.795-803
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    • 2005
  • This paper discusses the late nineteenth-century Korean intellectuals' understanding of Japanese customs on the basis of Ki-Su Kim(金綺秀)'s records. Ki-Su Kim was conservative on his inspection and observation trip to Japan Even though he was loyal to Chinese philosophy, he expressed his great interest when he was reluctant to see the Western technology flowered in Japan because it is not mentioned in Confucianism(朱子學). However, he, like mordern scholars in the later period of the Chosun dynasty, took an objective view of the military matters, such as the military training of soldiers, weapons, and others. On the one hand, he appreciated the western garment in that it, fitting the human body perfectly, makes people comfortable. In the later period of the Chosun dynasty, the Koreans had a sense of their superiority to the Japanese and held them in contempt, which had been rooted in the Japanese invasion of Chosun in the year of Imjin(AD 1592). Even around AD 1870, the Koreans regarded the Japanese as a barbarian or a savage, even though the Japanese had attempted to modernize their country with the introduction of the Western civilization since the renovation of Meizi(明治).

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