• Archives of Craniofacial Surgery
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• v.20 no.4
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• pp.219-222
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• 2019

The purpose of this study is to discuss several approaches to addressing naso-orbito-ethmoidal (NOE) fracture. Orbital fracture, especially infraorbital fracture, can be treated through the transconjunctival approach easily. However, in more severe cases, for example, fracture extending to the medial orbital wall or zygomatico-frontal suture line, only transconjunctival incision is insufficient to secure good surgical field. And, it also has risk of tearing the conjunctiva, which could injure the lacrimal duct. Also, in most complex types of facial fracture such as NOE fracture or panfacial fracture, destruction of the structure often occurs, for example, trap-door deformity; a fracture of orbital floor where the inferiorly displaced blowout facture recoils to its original position, or vertical folding deformity; fractured fragments are displaced under the other fragments, causing multiple-packed layers of bone.

• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.2
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• pp.108-113
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• 2005

The damageability and repairability of similar platform type vehicles could be very concerned with design optimization. In all the vehicles crash tested, small size passenger vehicles were weakness in aspect of damageability and repairability. The most critical area appears to be repair cost considering that parts cost is the largest portion of total repair cost segments. Besides repair cost, attaching method of front sidemember and subframe are placed special importance for impact energy absorption and damageability and repairability. So in order to improve damageability and repairability of vehicle structure and body component of the monocoque type passenger vehicles, the end of front side member and front back beam should be designed with optimum level and to supply the end of front side member as a partial condition approx 300mm. The effectiveness of design concept on the 40% offset frontal impact characteristics of the passenger vehicle structure is investigated and summarized.

• Biomolecules & Therapeutics
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• v.32 no.4
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• pp.474-480
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• 2024

Streptomyces avermitilis genome includes 33 genes encoding monooxygenation-catalyzing cytochrome P450 enzymes. We investigated the structure of CYP107P2 and its interactions with terpenoid compounds. The recombinant CYP107P2 protein was expressed in Escherichia coli and the purified enzyme exhibited a typical P450 spectrum upon CO-binding in its reduced state. Type-I substrate-binding spectral titrations were observed with various terpenoid compounds, including α-pinene, β-pinene, α-terpinyl acetate, and (+)-3-carene. The calculated binding affinities (Kd) ranged from 15.9 to 50.8 µM. The X-ray crystal structure of CYP107P2 was determined at 1.99 Å resolution, with a well-conserved overall P450 folding conformation. The terpenoid compound docking models illustrated that the structural interaction between monoterpenes and CYP107P2, with the distance between heme and terpenes ranging from 3.4 to 5.4 Å, indicates potential substrate binding for P450 enzyme. This study suggests that CYP107P2 is a Streptomyces P450 enzyme capable of catalyzing terpenes as substrates, signifying noteworthy advancements in comprehending a novel P450 enzyme's involvement in terpene reactions.

• International Journal of Control, Automation, and Systems
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• v.4 no.3
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• pp.382-393
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• 2006

Mechanical system dynamics plays an important role in the area of computational structural biology. Elastic network models (ENMs) for macromolecules (e.g., polymers, proteins, and nucleic acids such as DNA and RNA) have been developed to understand the relationship between their structure and biological function. For example. a protein, which is basically a folded polypeptide chain, can be simply modeled as a mass-spring system from the mechanical viewpoint. Since the conformational flexibility of a protein is dominantly subject to its chemical bond interactions (e.g., covalent bonds, salt bridges, and hydrogen bonds), these constraints can be modeled as linear spring connections between spatially proximal representatives in a variety of coarse-grained ENMs. Coarse-graining approaches enable one to simulate harmonic and anharmonic motions of large macromolecules in a PC, while all-atom based molecular dynamics (MD) simulation has been conventionally performed with an aid of supercomputer. A harmonic analysis of a macroscopic mechanical system, called normal mode analysis, has been adopted to analyze thermal fluctuations of a microscopic biological system around its equilibrium state. Furthermore, a structure-based system optimization, called elastic network interpolation, has been developed to predict nonlinear transition (or folding) pathways between two different functional states of a same macromolecule. The good agreement of simulation and experiment allows the employment of coarse-grained ENMs as a versatile tool for the study of macromolecular dynamics.

• Applied Microscopy
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• v.28 no.3
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• pp.283-297
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• 1998

Hemopoiesis and morphogenesis of the human fetal liver through from 10 to 32 weeks of gestation were investigated by light and electron microscopy. The results obtained were as follows. Hemopoiesis of fetal liver tissue was found from 10 to 32 weeks of gestation, but the hemopoiesis was decreased at 32 weeks of gestation. At the 32 weeks of gestation, matured erythrocytes were observed in the sinusoid, and formation of liver cell cord and portal triad were established. Differentiation of hepatic cell was characterized by the increase of amount of cell organelles within cytoplasm, decrease of hemopoietic cell, morphological change of nuclear envelope from folding form to round form during the developmental period. These results suggest that human fetal liver plays a hematopoietic function until bone marrow and spleen play their function, but morphology of liver at 32 weeks of gestation was differed with structure observed in liver of adult.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.8 no.4
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• pp.299-303
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• 2014

Demand of moving auxiliary equipment has increased recently to an increase in the elderly population. pedestrian demand is either moving auxiliary equipment are also increasing. regional migration, such as pedestrian and the elderly and patients is a device to support the sharing received walking the weight of inconvenient people. In this paper, by mounting the electric function to the current manual walking, to prepare the electric walking to support the user's walking. the design applies a lightweight folding structure so that it can be moved to a ride at long distances, were fabricated.

• Proceedings of the Korean Society For Composite Materials Conference
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• 1999.11a
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• pp.168-171
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• 1999

For the axial crushing tests of various shape of tubes, it was reported that composite tubes need trigger mechanism to avoid brittle failure. In this study, static axial crush tests were performed with the new aluminum/GFRP hybrid tubes. Glass/Epoxy prepregs were wrapped around aluminum tube and co-cured. The failure of hybrid tube was stable and progressive without trigger mechanism, and specific energy absorption was increased to maximum 34% in comparison with aluminum tube. Effective energy absorption is possible for inner aluminum tube because wrapped composite tube constrain the deflection of aluminum tube and reduce the folding length. The failure of hybrid composite tube was stable without trigger mechanism because inner aluminum tube could play the role of crack initiator and controller. Aluminum/Glass-Epoxy hybrid tube is suitable for the vehicle front structure due to effective energy absorption capability, easy production, and simple application for RTM process.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.12
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• pp.1734-1737
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• 2019

This paper presents a prediction structure with a Hybrid Dynamic Branch Prediction (HDBP) scheme which decreases the number of stalls. In the application, a branch history register is dynamically adjusted to produce more unique index values of pattern history table (PHT). The number of stalls is also reduced by using the modified gshare predictor with a long history register folding scheme. The aliasing rate decreased to 44.1% and the miss prediction rate decreased to 19.06% on average compared with the gshare branch predictor, one of the most popular two-level branch predictors. Moreover, Compared with the gshare, an average improvement of 1.28% instructions per cycle (IPC) was achieved. Thus, with regard to the accuracy of branch prediction, the HDBP is remarkably useful in boosting the overall performance of the superscalar processor.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.30 no.4
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• pp.42-48
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• 1998

The bacterial cellulose(BC) has many unique properties that are potentially and commercially beneficial. In order to enhance inherently inferior physical property of chemithermomechanical pulp(CTMP) sheet, chemical pulp has been used widely. Bacterial cellulose also has an enhanced sheet strength because of its unique physical and morphological features. This study was carried out to inverstigate the effect of BC addition on physical properties of CTMP sheets. The effect of BC addition on its optical properties was also discussed. The apparent density, internal bond strength, Young's modulus, tensile strength and folding endurance of CTMP sheet are increasing with increase of BC contents. This strength increase would be attributed to the increase of relative bonding sites among pulp fibers by addition of BC which has microfibrillar structure with very high specific surface areas. There were not so significant changes in opacity of CTMP sheet upto 20% addition level of BC, while over 40% addition, the opacity gradually decreased and levelled off. Porosity is decreased with addition of BC. This decrease would be attributed to densification of sheet by fine and filamentous structure of BC fibers.

• Journal of Korean Association for Spatial Structures
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• v.11 no.1
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• pp.113-120
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• 2011

Retractable roof system is one of the special feature in stadium or complex structure. And this retractable roof system makes possible to use spacial structure all-weather. This retractable roof system is able to classified into overlapping, parallel movement and folding system. Moving load, impact load, inertial or braking loads, these dynamic loads induced by movements of retractable roof system. So it is necessary to analysis of spacial structures are subjected to these dynamic loads. Dynamic loads that are induced by the retractable roof movements can be applied to moving mass method or moving force method. But, moving force method is appropriate because the retractable roof movements is slow relatively. In this paper, new application method of moving forces induced by the retractable roof movements is proposed. And vibration analysis of spacial structures are executed by using the proposed method. This proposed equivalent moving force can be easily applied to spacial structure that is subjected to dynamic loads induced by movement of the retractable roof system.