• Title/Summary/Keyword: In(III)

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TOAST Distribution of Ischemic Stroke Patients Admitted to Oriental Hospitals (한방 의료기관에 입원한 허혈성 뇌졸중 환자의 아형 분포)

  • Lee, Jung-Sup;Ko, Mi-Mi;Lee, Ju-Ah;Kang, Byoung-Kab;Cha, Min-Ho;Oh, Dal-Seok;Bang, Ok-Sun
    • The Journal of Korean Medicine
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    • v.31 no.5
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    • pp.82-89
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    • 2010
  • Objectives: The aim of this study was to determine distribution patterns of TOAST subtypes of ischemic stroke patients admitted to oriental hospitals and to get a better understanding of present conditions in oriental medicine by comparing with the Korea stroke registry (KSR), the largest and representative data. Methods: Clinical data were collected from acute ischemic stoke patients. MRI studies including vascular images were performed in all cases. TOAST criteria were used to determine subtypes of ischemic stroke patients. According to the duration from disease onset to hospital admission time, patients were assigned to 3 groups (Group I0 to 3 d, Group II4 to 7 d, Group III8 to 28 d) and the distribution of TOAST subtypes were compared among these three groups. Results: We collected 514 sets of clinical data from 10 oriental hospitals between May 2007 and September 2009. Small vessel occlusion (SVO) subtype was the most common (57.62%), followed by large artery atherosclerosis (LAA, 29.98%). Compared with TOAST distribution of KSR, the proportion of ischemic stroke patients with SVO subtype was higher than that of KSR. On the other hand the proportion of patients with stroke of undetermined etiology (SUE) was lower. Distributions of SVO, LAA and cardioembolism (CE) in group were I 66.4%, 23.8% and 8.9%, respectively; those in group IIIwere 51.03%, 34.71% and 11.57%, respectively. Conclusions: In oriental hospitals, the proportion of ischemic stroke patients diagnosed as SVO type was higher than that of KSR. At early stage (from onset to 2 d) proportion of SVO was very high, however after 7 days from onset it decreased with concomitant increases in proportions of LAA and CE. These phenomena may be due to the facts that 1) at early stage emergency treatments are limited in oriental hospitals, 2) after early stage many patients prefer oriental treatments, including rehabilitation.

Dietary Changes After Breast Cancer Diagnosis: Associations with Physical Activity, Anthropometry, and Health-related Quality of life Among Korean Breast Cancer Survivors (한국인 유방암 경험자의 유방암 진단 후 식사변화: 신체활동, 신체측정치, 그리고 건강관련 삶의 질과의 연관성)

  • Song, Sihan;Youn, Hyun Jo;Jung, So-Youn;Lee, Eunsook;Kim, Zisun;Cho, Jihyoung;Yoo, Young Bum;Moon, Hyeong-Gon;Noh, Dong-Young;Lee, Jung Eun
    • Korean Journal of Community Nutrition
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    • v.21 no.6
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    • pp.533-544
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    • 2016
  • Objectives: We aimed to examine levels of physical activity, anthropometric features, and health-related quality of life (HRQoL) among Korean breast cancer survivors who reported changes in their diet after diagnosis. Methods: A total of 380 women who had been diagnosed with stage I to III breast cancer and had breast cancer surgery at least six months before the interview were included. Participants provided information on dietary change after diagnosis, post-diagnostic diet, physical activity, anthropometric measures, and HRQoL through face-to-face interview. We assessed HRQoL levels of breast cancer survivors using a validated Korean version of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) and Breast Cancer Module (BR23). We used the logistic regression and generalized linear models to identify the associations of dietary changes in relation with physical activity, anthropometry, and HRQoL. Results: The majority of participants (72.6%) reported that they have changed their diet to a healthier diet after diagnosis. Breast cancer survivors who reported to have change to a healthy diet had higher intakes of vegetables and fruits and lower intakes of red and processed meats, and refined grains than those who did not. Also, survivors with a healthy change in their diet were more likely to engage in physical activity (top vs. bottom tertile: odds ratio [OR], 1.85; 95% confidence interval [95% CI], 1.02-3.36) and have lower body mass index (BMI) (OR, 0.90; 95% CI, 0.82-0.98 for one $kg/m^2$ increment in BMI) compared to those who did not. We found that a healthy change in diet was associated with higher scores of physical functioning (p=0.02) and lower scores of constipation (p=0.04) and diarrhea (p=0.006) compared to those who did not. Conclusions: Healthy changes in diet after breast cancer diagnosis may be associated with lower levels of BMI, and higher levels of physical activity and HRQoL.

Evaluation of Lanthanum(III)-Loess Composite as an Adsorbent for Phosphate Removal (인 제거를 위한 흡착제로서 란타늄-황토 복합체의 흡착특성)

  • Shin, Gwan-Woo;Choo, Yeon-Duk;Kim, Keum-Yong;Ryu, Hong-Duck;Lee, Sang-Ill
    • Journal of Korean Society of Environmental Engineers
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    • v.33 no.2
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    • pp.143-148
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    • 2011
  • In this work, a composite formed by adding loess with lanthanium ("La-Loess") was proposed for effective removal of phosphate found in confined water bodies such as lake and reservoir. It was found that the theoretical maximum amount of lanthanum that can be attached to Loess was 2.68 mg La/g Loess. The phosphate removal was enhanced as an added amount of La-Loess composite increased. Furthermore, there was a noticeable difference in phosphate removal between Loess and La-Loess as the latter required 1.5 to 10 times less Loess than the former. Both Isotherm equations of Freundlich and Langmuir can be used to explain the phosphate adsorption characteristics in using La-Loess composites. The phosphate removal was very effective in the pH range of 5~8, which means that the proposed adsorbent can be directly applied to natural water without adjusting pH. Also, the La-Loess composites were well settled within 30 min without causing turbidity in water. Consequently, the proposed La-Loess can be strongly recommended for phosphate removal in confined water bodies.

Birth Weight and the Development of Functional Gastrointestinal Disorders in Infants

  • Baldassarre, Maria Elisabetta;Di Mauro, Antonio;Salvatore, Silvia;Tafuri, Silvio;Bianchi, Francesco Paolo;Dattoli, Enzo;Morando, Lucia;Pensabene, Licia;Meneghin, Fabio;Dilillo, Dario;Mancini, Valentina;Talarico, Valentina;Tandoi, Francesco;Zuccotti, Gianvincenzo;Agosti, Massimo;Laforgia, Nicola
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.23 no.4
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    • pp.366-376
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    • 2020
  • Purpose: To assess the association between birth weight and the development of functional gastrointestinal disorders (FGIDs) in the first year of life. Methods: This is a secondary analysis of a prospective cohort multicenter study including neonates, consecutively enrolled at birth, and followed up for one year. At birth all infants were classified by birth weight as extremely low (ELBW), very low, or low when <1,000, <1,500, and <2,500 g, respectively, and by birth weight for gestational age as appropriate (AGA, weight in the 10-90th percentile), small (SGA, weight <10th percentile), and large (LGA, weight >90th percentile) for gestational age. FGIDs were classified according to the Rome III criteria and assessed at 1, 3, 6, and 12 months of life. Results: Among 1,152 newborns enrolled, 934 (81.1%) completed the study: 302 (32.3%) were preterm, 35 (3.7%) were ELBW, 104 (11.1%) were SGA, 782 (83.7%) were AGA, and 48 (5.1%) were LGA infants. Overall, throughout the first year of life, 718 (76.9%) reported at least one FGID. The proportion of infants presenting with at least one FGID was significantly higher in ELBW (97%) compared to LBW (74%) (p=0.01) and in LGA (85.4%) and SGA (85.6%) compared to AGA (75.2%) (p=0.0001). On multivariate analysis, SGA was significantly associated with infantile colic. Conclusion: We observed an increased risk of FGIDs in ELBW, SGA, and LGA neonates. Our results suggest that prenatal factors determining birth weight may influence the development of FGIDs in infants. Understanding the role of all potential risk factors may provide new insights and targeted approaches for FGIDs.

Evaluation of Agronomic Characteristics and Forage Production of Domestic and Foreign Italian Ryegrass Cultivar in Korea (국내육성 및 외국도입 이탈리안 라이그라스 품종의 생육특성 및 사초 생산성 평가)

  • Ko, Ki Hwan;Kim, Jong Kwan;Kim, Jong Duk
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.35 no.4
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    • pp.297-302
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    • 2015
  • This experiment was conducted to evaluate the agronomic characteristics and forage production of Italian ryegrass cultivars at three locations (Gurae, Sungju and Cheonan) from 2013 to 2014. The experiment employed a randomized complete block design with three replications. The seven cultivars used in this experiment were 'Korwinearly', 'Florida80', 'YounbongI', 'YounbongII', 'YounbongIII', 'KeimyungI' and 'KeimyungII' varieties. Italian ryegrass varieties were seeded on October 4 at Gurae, October 8 at Seongju and October 3 at Cheonan in 2013. The Italian ryegrass varieties were harvested on April 26 at Gurae and Seongju, and on April 24 at Cheonan in 2014. Although the seven cultivars had resistance to foliar diseases and insects and high winter survival, they has little lodging resistance. The heading dates for 'Younbong I', 'Younbong II' and 'Keimyung I' were earlier than for other varieties at the three locations. Dry matter (DM) content and plant height in the early maturing cultivars were higher than in other cultivars at the three locations. The fresh and DM yields of the early maturing cultivars were also higher than others at the three locations. The results of this experiment indicate that the heading date for early maturing cultivars is earlier, and the plant height is higher than for other cultivars. Early maturing cultivars had higher DM content as well as fresh and DM yields of Italian ryegrass. Therefore, early maturing cultivars should be recommended as high-yield forage in double-cropping systems because of their superior production of forage and early heading date.

Studies on the Relation between Characteristics of Stem and Leaf Area and Weight in the Mulberry Tree (뽕나무지조의 성상과 엽면적 및 엽중과의 관계에 관한 연구)

  • 김호락;김문협
    • Journal of Sericultural and Entomological Science
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    • v.13 no.1
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    • pp.1-11
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    • 1971
  • This study are conducted to observe the correlation which are concerned with tile internode length to the leaf area and leaf weight. Where as, small leaf variety Gae Ryang Su Ban, and large leaf variety Ro Sang are adopted to observe their correlations in a group consisting of 30 varieties and in identifiable varieties. The results are as follows: A. Such positive correlations are observed between each characteristics and leaf area with leaf weight. (1) There are highly positive correlation between internode length and leaf area with leaf weight together within varieties group. (2) No correlation with stem length is observed, but high correlation is acknowledged in identifiable varieties although positive correlations are recognized. (3) Correlations are showed between stem volume and leaf area with leaf weight in identifiable varieties, especially Gae Ryang Su Ban higher than any other varieties. (4) Petiole length is not correlated to leaf area and leaf weight in varieties group, but petiole weight is highly correlated to leaf area and leaf weight in varieties group, Gae Ryang Su Ban and Ro Sang variety. B. Internode length along with the stem parts shows the same tendency of variance as most varieties do; internode length of I part at the base is the longest one, gradually shrunk to that of III part and gloved longer, and again internode length becomes shorter to the top. C. Variance of leaf area and leaf weight along with the parts are the lowest ones at the I part, gradually increased to the maximum at IV part, and here after it comes to shrink.

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Analysis of the Outcomes of Surgically-Treated Spinal Epidural Hematomas (척추 경막외 출혈에 대한 수술적 치료성적 분석)

  • Cho, Young-Hyun;Park, Jin-Hoon;Kim, Ji-Hoon;Roh, Sung-Woo;Kim, Chang-Jin;Jeon, Sang-Ryong
    • Journal of Trauma and Injury
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    • v.23 no.2
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    • pp.163-169
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    • 2010
  • Purpose: Spinal epidural hematoma (EDH) is a rare condition requiring an urgent diagnosis and management. We describe here the clinical features, magnetic resonance image (MRI) findings, and outcomes of surgery in six patients with spinal EDH. Methods: We retrospectively analyzed six patients who underwent surgery for spinal EDH between April 2004 and May 2010. Preoperative MRI findings within 48 hours of symptom occurrence were analyzed for cord compression, extent of EDH, and presence of vascular abnormalities. Pre- and postoperative neurological status was also assessed comparatively. Results: Our six patients consisted of three men and three women, with a mean age of 70 years (range: 54-88 years), who presented with the back pain or motor weakness. The mean follow-up period was 34 months (range: 2-72 months). Two patients had cardiovascular disease and were taking warfarin, but the others had no history of medical comorbidity. Those two patients taking warfarin had a history of trauma, another one experienced symptoms during a strenuous effort, and the others developed spontaneously. Before surgery, motor power was grade III in three patients, grade 0 in two patients, and normal in one patient. Preoperative MRI showed no vascular abnormalities except for the EDH in any patient. At the last follow-up, all those five patients with motor weakness showed neurological improvement compared to their preoperative status. There were no complications related to surgery. All six patients were able to ambulate with or without an assistive device. Conclusion: Spinal EDH can occur in patients without trauma, bleeding diathesis, or combined vascular pathology. The surgical outcomes of spinal EDH seem to be satisfactory, even in quadriplegic patients.

Conservation Management Methods and Vascular Plants of Major Sites in Changwon-si (창원시 주요지역의 식물상 및 보전관리방안)

  • Oh, Hyun-Kyung;Kang, Hyun-Mi;Choi, Song-Hyun
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.15 no.4
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    • pp.23-40
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    • 2012
  • The vascular plants of major sites in Changwon-si were listed 456 taxa (9.3% of all 4,881 taxa of vascular plants); 112 families, 293 genera, 371 species, 2 subspecies, 66 varieties and 17 forms. The vascular plants of Changwon-cheon were listed 133 taxa, Junam reservoir were listed 90 taxa, Seongju-sa were listed 293 taxa, and Yungji park were listed 164 taxa. Divided into 456 taxa; woody plants were 160 taxa (35.1%) and herbaceous plants were 296 taxa (64.9%). Furthermore, therophytes (Th) were 111 taxa (24.3%), hemicryptophytes (H) were 75 taxa (16.4%), megaphanerophytes (MM) were 63 taxa (13.8%) showed high proportional ratio in life form. Based on the list of rare plants by the Korea Forest Service and Korea National Arboretum, 10 taxa (1.8% of all 571 taxa of rare plants); Aristolochia contorta (LC), Euryale ferox (VU), Melothrua japonica (LC), Utricularia pilosa (CR), Hydrocharis dubia (LC), Carex idzuroei (DD), Acorus calamus var. angustatus (LC), etc. Based on the list of endemic plants by the Korea National Arboretum, 10 taxa (3.0% of all 328 taxa of endemic plants); Salix pseudolasiogyne, Philadelphus incanus, Indigofera koreana, Lespedeza ${\times}$ maritima, Stewartia pseudocamellia, Weigela subsessilis, Carex okamotoi, etc. Based on the list of specific plants by floral region were total 43 taxa (4.0% of all 1,071 taxa of specific plants); 4 taxa (Euryale ferox, Hydrocharis dubia, Carex idzuroei, etc.) in class IV, 9 taxa (Ilex crenata, Acer palmatum, Stewartia pseudocamellia, Melothria japonica, Fatsia japonica, etc.) in class III, 3 taxa (Caltha palustris var. membranacea, Nymphoides indica, etc.) in class II, 26 taxa (Cyrtomium fortunei, Chloranthus japonicus, Quercus variabilis, Ulmus parvifolia, Aphananthe aspera, etc.) in class I. Based on the list of naturalized plants, 48 taxa (Rumex crispus, Chenopodium album var. album, Amaranthus patulus, Phytolacca american, Brassica juncea var. integrifolia, Potentilla paradoxa, Robinia pseudoacacia, Euphorbia maculata, Oenothera odorata, Cuscuta pentagona, Veronica persica, Plantago lanceolata, Diodia teres, Helianthus tuberosus, Dactylis glomerata, etc.), naturalization rate was 10.5% of all 456 taxa of vascular plants and urbanization index was 15.0% of all 321 taxa of naturalized plants. Ecosystem disturbing wild plants were 3 taxa (Rumex acetocella, Solanum carolinense, Ambrosia artemisiifolia).

Fundamentals of Ecotoxicity Evaluation Methods Using Domestic Aquatic Organisms in Korea: (KII) Green Algae (국내 생물종을 이용한 생태독성평가 기반연구: (III) 녹조류)

  • An, Youn-Joo;Nam, Sun-Hwa;Baek, Yong-Wook
    • Korean Journal of Ecology and Environment
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    • v.41 no.2
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    • pp.117-127
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    • 2008
  • Green algae are important primary producers in aquatic ecosystem, and they are sensitive test species in bioassay. Green algae are broadly used to assess the adverse effects of various chemicals by measuring the inhibition of metabolism, reproduction and survival. In this study, we extensively gathered domestic and foreign toxicity test methods conducted using green algae, which are distributed in Korean water environment. Selected eight domestic green algae were Chlamydomonas reinhardtii, Desmodesmus subspicatus (=Scenedesmus subspicatus), Scenedesmus abundans, Scenedesmus acutus, Scenedesmus quadricauda, Podohedriella falcata (=Ankistrodesmus falcatus), Pseudokirchneriella subcapitata (=Selenastrum capricornutum), and Chlorella vulgaris. Forty four test methods were collected from the standard test ones, government reports, SCI papers and Korean research papers. P. subcapitata and D. subspicatus are the most common test species recommended by the standard test methods. Initial cell density and dilution water were the main differences among the test methods we collected. We proposed the suitable ecotoxicity test methods based on domestic green algae in Korea. This study could be a fundamental basis to establish the ecotoxicity test methods by green algae distributed in Korea.

T-lymphocyte Inactivation and Anti-atopic Effects of Diarylheptanoid Hirsutenone Isolated from Alnus japonica (오리나무유래 디아릴헵타노이드 허수테논의 T 세포활성억제 및 항아토피 효능연구)

  • Lee, Do Ik;Seo, Seong Jun;Joo, Seong Soo
    • Korean Journal of Food Science and Technology
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    • v.45 no.4
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    • pp.508-514
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    • 2013
  • 2Department of Marine Molecular Biotechnology, College of Life Science, Gangneung-Wonju National University Recently, we reported that diarylheptanoid hirsutenone (HST) effectively inactivated T lymphocytes. However, it has not been evaluated whether HST is involved in calcineurin or calmodulin inactivation. In the present study, cells were treated with T-cell inhibitors with or without HST. Our results revealed that HST successfully inhibited expression of T-helper type I (Th1) and Th2 cytokines. Co-treatment with HST and nuclear factor-activated T cell (NFAT) activation inhibitor III (INCA-6) showed a more sensitive effect than that with other inhibitors, suggesting that HST contributes to inhibition of dephosphorylation of NFAT in the cytosol. HST up-regulated cell cycle arrest genes and inhibited the growth of Staphylococcus aureus. These effects were confirmed in an NFAT electrophoretic-mobility shift assay via successful inhibition of NFAT translocation and in the histological recovery in a 2,4-dinitrochloro benzene-induced in vivo model. Taken together, HST was shown to effectively inhibit T-cell activation via inhibition of cytosolic NFAT dephosphorylation, similar to INCA-6.