• Title/Summary/Keyword: Improving Quality of Life

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Genome-wide Association Study of Integrated Meat Quality-related Traits of the Duroc Pig Breed

  • Lee, Taeheon;Shin, Dong-Hyun;Cho, Seoae;Kang, Hyun Sung;Kim, Sung Hoon;Lee, Hak-Kyo;Kim, Heebal;Seo, Kang-Seok
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.3
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    • pp.303-309
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    • 2014
  • The increasing importance of meat quality has implications for animal breeding programs. Research has revealed much about the genetic background of pigs, and many studies have revealed the importance of various genetic factors. Since meat quality is a complex trait which is affected by many factors, consideration of the overall phenotype is very useful to study meat quality. For integrating the phenotypes, we used principle component analysis (PCA). The significant SNPs refer to results of the GRAMMAR method against PC1, PC2 and PC3 of 14 meat quality traits of 181 Duroc pigs. The Genome-wide association study (GWAS) found 26 potential SNPs affecting various meat quality traits. The loci identified are located in or near 23 genes. The SNPs associated with meat quality are in or near five genes (ANK1, BMP6, SHH, PIP4K2A, and FOXN2) and have been reported previously. Twenty-five of the significant SNPs also located in meat quality-related QTL regions, these result supported the QTL effect indirectly. Each single gene typically affects multiple traits. Therefore, it is a useful approach to use integrated traits for the various traits at the same time. This innovative approach using integrated traits could be applied on other GWAS of complex-traits including meat-quality, and the results will contribute to improving meat-quality of pork.

Study on the Effect of the Rural Development Projects on the Quality of Life for Residents in Rural Areas (일반농산어촌개발사업이 농촌 지역주민 삶의 질에 미치는 영향)

  • Park, Jun-Gyu;Kim, Min-Su;Kim, Yeong-Ha
    • Journal of Korean Society of Rural Planning
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    • v.23 no.4
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    • pp.75-90
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    • 2017
  • The study was intended to identify the effect of the rural development projects (comprehensive improvement of the seats of Eup and Myeon and regional unit comprehensive development projects) on the quality of life in rural areas against local residents living in areas subject to those projects by means of structural equation modeling based on covariance structure analysis. The result indicated that perception factors affecting the quality of life for residents in rural areas by the projects included 'improvement in spatial environment', 'increase in vitality of rural areas', and 'promotion of community activities.' It was also suggested that 'improvement in spatial environment' and 'increase in vitality of rural areas' have significantly positive effect on the quality of life for residents in rural areas while the former has relatively higher correlation. In comparison between comprehensive improvement of the seats of Eup and Myeon and regional unit comprehensive development projects, it was analyzed that all the perception factors of the comprehensive improvement of the seats of Eup and Myeon have effect on the quality of life for residents in rural areas indicating that comprehensive improvement of the seats of Eup and Myeon is more effective than regional unit comprehensive development projects in promoting the community activities. It means that existing rural development projects have been promoted to improve spatial environment rather than improving the quality of life for residents in rural areas. Thus, it is considered that the rural development projects in future should seek for a sense of community so that they can induce voluntary participation by local residents.

Mediating Effect of Depression on Self-rated Health and Quality of Life of Middle-aged and Elderly in Rural Areas (농촌지역 중노년층 주민의 주관적 건강상태와 삶의 질 관계에서 우울의 매개효과)

  • Kim, Yun-Young;Hyun, Hye-Sun;Bang, Hwal Lan
    • Journal of the Korea Convergence Society
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    • v.11 no.5
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    • pp.317-325
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    • 2020
  • The purpose of this study was to examine the mediating effect of depression in relation to the subjective health status and quality of life of middle-aged and elderly in rural areas. Subjective health status, depression and quality of life of 235 residents over 40 years of age in A county were collected and analyzed with t-test, ANOVA, Pearson's Correlation, and Multiple Regression, and verified with Sobel test. Depression had a mediating effect in relation to the subjective health status and quality of life of the residents. In conclusion, subjective health conditions and depression are important factors that determine the quality of life of middle-aged and elderly residents in rural areas. Various programs for improving subjective health of the residents and relieving their depression are needed to improve the quality of life of middle-aged and elderly in rural areas.

Effects of Kinect-Based Mixed Reality Device on Physical Function and Quality of Life in Breast Cancer Survivors : A randomized controlled trial

  • Byung-Gul Lim;Xinxing Li;Yun-Ho Sung;Si-Woo LEE;Hyun-Jun Kim;Wook Song
    • Journal of The Korean Society of Integrative Medicine
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    • v.11 no.2
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    • pp.49-60
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    • 2023
  • Purpose : We aimed to evaluate the impact of a exercise with kinect-based mixed reality device (KMR) on physical function, upper extremity disability, fatigue, and quality of life in breast cancer survivors. We hypothesized that this exercise program would improve physical function, physical activity, fatigue, and quality of life. Methods : Thirty-nine breast cancer survivors were randomized to either the KMR exercise group (KE) or the home stretch group (HS). The KE participated in 8 weeks of exercise, exercising 3 times per week, while the HS performed 8 weeks of stretching exercises, also 3 times per week. Before and after the intervention period, participants underwent assessments of physical function, including body composition, chester step test (CST), and hand grip strength (HGS). Additionally, participants completed questionnaires including the international physical activity questionnaire (IPAQ), disabilities of the arm, shoulder and hand (DASH) questionnaire, and functional assessment of cancer therapy-breast (FACT-B) questionnaire to measure their physical activity levels, upper extremity disability, and quality of life, respectively. Results : Overall, significant improvements were observed in several shoulder movements, body weight, and physical activity, with no significant interaction effects between groups and time. Furthermore, there was a significant group by time interaction for body weight, left flexion, right flexion, right abduction, and left adduction, as well as for upper extremity disability (K-DASH) and quality of life (FACT-B). Conclusion : In conclusion, the KMR exercise program was found to be effective at improving physical function, upper extremity disability, quality of life, and overall well-being in breast cancer survivors. The significant improvements observed in multiple measures and the significant group by time interactions for various outcomes highlight the potential benefits of this KMR exercise program in promoting a better quality of life for breast cancer survivors.

The Effects of Self-Efficacy Promoting Cardiac Rehabilitation Program on Self- Efficacy, Health Behavior, and Quality of Life

  • Song, Kyung Ja
    • Journal of Korean Academy of Nursing
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    • v.33 no.4
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    • pp.510-518
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    • 2003
  • Background. Ischemic heart disease results from athesclerotic changes of the coronary artery. These changes are aggravated by hypercholesterolemia, smoking, obesity, lack of exercise, coronary-prone personality, and stress. Because these risk factors affect not only the prevalence of the ischemic heart disease but also recurrence of the disease, cardiac rehabilitation programs were introduced to help patients with ischemic heart disease reduce risk factors. Diverse cardiac rehabilitation programs are needed to motivate participation in cardiac rehabilitation and to enhance patients' quality of life. Objectives. To examine the effect of a self-efficacy promoting cardiac rehabiltation program on self-efficacy, health behavior and quality of life of patients with ischemic heart disease. Methods. Data were collected from 45 hospitalized ischemic heart disease patients. Medical records were reviewed to obtain demographic and clinical characteristics. Data regarding self-efficacy, health behavior, and quality of life were obtained from interviews using structured questionnaires. The nonequivalent control group non-synchronized design was used to conduct this study. One session of conventional group education was given to patients in the control group while they were in the hospital. Patients in the experimental group participated in a newly developed cardiac rehabilitation program. It focused on strengthening self-efficacy with four self-efficacy sources-performance accomplishment, vicarious experiences, verbal persuasion and physical status using two individualized in-hospital education sessions and four weekly telephone counseling follow-up calls after discharge. Results. Four weeks after discharge, the increment of total self-efficacy score was significantly higher in the experimental group than in the control group (p<.0l). There was also a significant difference in the total quality of life scores increments between the two groups (p<.0l). However, no significant changes were noted in the increments of total health behavior scores between the two groups. Conclusion. A cardiac rehabilitation program focusing on promoting self-efficacy was effective in improving self-efficacy, and quality of life of patients with ischemic heart disease.

Symptom Management to Predict Quality of Life in Patients with Heart Failure: A Structural Equation Modeling Approach (증상관리를 통한 심부전 환자의 삶의 질 예측모형)

  • Lee, Ja Ok;Song, Rhayun
    • Journal of Korean Academy of Nursing
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    • v.45 no.6
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    • pp.846-856
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    • 2015
  • Purpose: The focus of this study was on symptom management to predict quality of life among individuals with heart failure. The theoretical model was constructed based on situation-specific theory of heart failure self-care and literature review. Methods: For participants, 241 outpatients at a university hospital were invited to the study from May 19 to July 30, 2014. Data were collected with structured questionnaires and analyzed using SPSSWIN and AMOS 20.0. Results: The goodness of fit index for the hypothetical model was .93, incremental fit index, .90, and comparative fit index, .90. As the outcomes satisfied the recommended level, the hypothetical model appeared to fit the data. Seven of the eight hypotheses selected for the hypothetical model were statistically significant. The predictors of symptom management, symptom management confidence and social support together explained 32% of the variance in quality of life. The 28% of variance in symptom management was explained by symptom recognition, heart failure knowledge and symptom management confidence. The 4% of variance in symptom management confidence was explained by social support. Conclusion: The hypothetical model of this study was confirmed to be adequate in explaining and predicting quality of life among patients with heart failure through symptom management. Effective strategies to improve quality of life among patients with heart failure should focus on symptom management. Symptom management can be enhanced by providing educational programs, encouraging social support and confidence, consequently improving quality of life among this population.

Effect of Unmet Healthcare Needs on Quality of Life (미충족 의료 경험이 삶의 질에 미치는 영향)

  • Lee, Jeong Wook
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.9
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    • pp.283-290
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    • 2020
  • The purpose of this study was to investigate the potential causal relationship between unmet healthcare needs and metrics related to quality of life. To examine the relationships between these variables, the study conducted an analysis by processing additional irradiated raw materials of the Korean Medical Panel. The metrics related to quality of life included six variables: athletic ability, self-care, daily activities, pain/trouble, uneasiness/depression, and subjective health conditions. Linear regression analysis revealed that the unmet healthcare needs had statistically significant negative effects on all six quality of life variables. A review of the magnitude of the linear regression β values for those variables showed that the relative level of influence on the quality of life variables decreased in the following order: pain/trouble, subjective health conditions, uneasiness/depression, daily activities, athletic ability, and self-care. Based on the results, practical applications related to strengthening working-level links between health and welfare is considered an effective policy response to the continued presence of unmet healthcare needs; such applications could contribute to improving the quality of life of those with unmet healthcare needs.

Moderating Effect of the Resilience in the Relationship between Job Stress and Quality of Life of Employees with Mentally Disabled (취업정신장애인의 직무스트레스와 삶의 질과의 관계에서 회복탄력성의 조절효과)

  • Choi, Hee-Chul
    • Journal of Digital Convergence
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    • v.15 no.2
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    • pp.431-439
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    • 2017
  • This study was conducted for the purpose of providing help to preparation of preventive intervention plans on job stress and the quality of life by investigating how resilience affects the relationship between job stress and the quality of life of the employed mentally disabled. As for the methods, this study collected materials by combining mail survey and visiting survey through a self-administered method targeting 113 mentally disabled who have been cared at community psychiatric rehabilitation centers in Seoul and Gyeonggi, and been employed for more than 3 months after the researcher of this study gave explanation to and asked for consent to the staffs of the centers. Study results show that job stress perceived by the employed-disabled exerts a significant influence on the quality of life, and resilience have a significant mediating effect between job stress and the quality of life. Through the above results, this study showed a possibility to apply resilience of the employed mentally disabled as an internal countermeasure, suggesting a comprehensive intervention plan for lowering job stress and improving the quality of life.

Factors Influencing Health-Related Quality of Life in the Elderly by Age (노인의 연령별 건강 관련 삶의 질에 영향 요인)

  • Hong, Ju-Youn
    • The Journal of the Korea Contents Association
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    • v.22 no.2
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    • pp.420-430
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    • 2022
  • The study attempted a comprehensive assessment of factors affecting health-related quality of life in the young-old and old-old. Data from the Community Health Survey for 5 years from 2015 to 2019 were analyzed. Research Results Health-related quality of life appears to be higher in the elderly than in the late-stage elderly, and various factors such as age, education level, household income, presence or absence of economic activity, presence or absence of moderate physical activity, stress or presence, and subjective health level Has been found to affect health-related quality of life. In particular, good or bad subjective health and subjective oral health had the greatest influence. In terms of the household type, the quality of life was high in young-old adults living in a three-generation household and old-old adults living in a one-generation household. Considering these characteristics, public policy programs should be developed and implemented to help the elderly with successful aging by improving their quality of life.

Cognitive Behavioral Therapy for Psychological Distress, Self Care and Quality of Life in Patients with Cancer: A Meta-analysis (인지행동중재가 암 환자의 심리적 디스트레스, 자기간호 및 삶의 질에 미치는 효과: 메타분석)

  • Oh, Pok Ja;Lee, Eun Ai
    • Korean Journal of Adult Nursing
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    • v.25 no.4
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    • pp.377-388
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    • 2013
  • Purpose: The purpose of this study was to assess the effects of cognitive behavioral therapy (CBT) on depression, anxiety, self care behavior and quality of life in cancer patients. Methods: Two thousand and eighty three abstracts were identified through six electronic databases (1980 to June 2012) in Korea. Seventeen studies involving 679 participants met the inclusion criteria for meta analysis. Two authors independently assessed trial quality by Cochrane's Risk of Bias and Methodological Items for Non Randomized Studies and extracted data. The data were analyzed by the RevMan 5.2 program of Cochrane library. Results: Overall, study quality was moderate to high. CBT was conducted for a mean of 4.2 weeks, 7 sessions and an average of 36.1-minutes per session. CBT was effective for depression (d=-0.85; 95% CI=-1.09, -0.61), anxiety (d=-0.52; 95% CI=-0.75, -0.29), self care behavior (d=-1.34; 95% CI=-1.93, -0.74), and quality of life (d=-0.42; 95% CI=-0.80, -0.04). Publication bias was not detected as evaluated by funnel plot and Egger's test. Conclusion: CBT has small to large effects on depression, anxiety, self care and quality of life. These finding suggests that various CBT interventions can assist cancer patients in reducing emotional distress and improving self care and quality of life.