• 제목/요약/키워드: Improved synthesis

검색결과 808건 처리시간 0.026초

Controlled synthesis of mesoporous codoped titania nanoparticles and their photocatalytic activity

  • Mathis, John E.;Kidder, Michelle K.;Li, Yunchao;Zhang, Jinshui;Paranthaman, M.P.
    • Advances in nano research
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    • 제4권3호
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    • pp.157-165
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    • 2016

  • The photocatalytic (PC) activity of anatase titania nanoparticles can be improved through codoping with transition metals and nitrogen. In addition, the PC activity can also be improved by creating monodisperse, mesoporous nanoparticles of titania. The question naturally arose as to whether combining these two characteristics would result in further improvement in the PC activity or not. Herein, we describe the synthesis and photocatalytic characteristics of codoped, monodisperse anatase titania. The transition metals tested in the polydisperse and the monodisperse forms were Mn, Co, Ni, and Cu. In each case, it was found that the monodisperse version had a higher PC activity compared to the corresponding polydisperse version.

  • https://doi.org/10.12989/anr.2016.4.3.157 인용 KSCI

An Improved Convergent Approach for Synthesis of Erlotinib, a Tyrosine Kinase Inhibitor, via a Ring Closure Reaction of Phenyl Benzamidine Intermediate

  • Asgari, Davoud;Aghanejad, Ayuob;Mojarrad, Javid Shahbazi
    • Bulletin of the Korean Chemical Society
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    • 제32권3호
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    • pp.909-914
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    • 2011

  • An improved convergent and economical method has been developed for the synthesis of erlotinib, a 4-anilinoquinazoline and an EGFR-tyrosine kinase inhibitor for treatment of non-small-cell lung cancer. The final two steps for the formation of this 4-anilinoquinazoline from suitable 2-aminobenzonitrile intermediate and 3-ethynylaniline were modified and were performed in a simple one-pot reaction. The ring-closing mechanism for the formation of erlotinib from the suitable formamidine intermediate and 3-ethynylaniline was investigated and determined to proceed via the formation of phenyl benzamidine intermediate rather than involving Dimroth rearrangement reported earlier. The new benzamidine intermediate was isolated for the first time and characterized.

  • https://doi.org/10.5012/bkcs.2011.32.3.909 인용 PDF KSCI

A Convenient One-Pot Biginelli Reaction Catalyzed by Y(OAc)3: An Improved Protocol for the Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones and Their Sulfur Analogues

  • Aridoss, Gopalakrishnan;Jeong, Yeon-Tae
    • Bulletin of the Korean Chemical Society
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    • 제31권4호
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    • pp.863-868
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    • 2010

  • Yttrium(III) acetate hydrate-catalyzed novel synthesis of 3,4-dihydropyrimidin-2(1H)-(thio)one derivatives was achieved through one-pot three-component condensation of diversified aldehydes, $\beta$-ketoesters and urea or N-methylurea or thiourea with a molar ratio of 1:1:1.4. In comparison to the classical Biginelli approach, this catalytic method has the advantages of short reaction time and improved product yield.

  • https://doi.org/10.5012/bkcs.2010.31.04.863 인용 PDF KSCI

The Revolution of Diamond Synthesis Technology

  • Sung, James-C.;Hu, Shao-Chung;Lin, I-Chiao;Tsai, Chia-Cheng
    • 한국분말야금학회:학술대회논문집
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    • 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part2
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    • pp.1136-1137
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    • 2006

  • The ultrahigh pressure process for synthesizing diamond grits is due to make a quantum leap: the raw materials will incorporate diamond seeds with a predetermined pattern. The result is doubling the diamond yield with a narrower size distribution. Moreover, the shape of diamond crystals can be precisely tuned. For example, diamond octahedra or diamond cubes, that are not available today, can be mass-produced. The new technology is now being implemented worldwide so the future diamond grits will have improved quality at reduced prices.

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