• Title/Summary/Keyword: Improved SCA

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A Case Report on Spinocerebellar Ataxia Type 2 (제2형 척수소뇌실조 환자 치험 1례)

  • An, Da-young;Han, Seung-hee;Nam, Hyun-seo;Han, Su-zy;Kim, Mi-kyung;Sun, Seung-ho
    • The Journal of Internal Korean Medicine
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    • v.42 no.5
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    • pp.784-792
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    • 2021
  • Objectives: The purpose of this study was to investigate a case of a patient with spinocerebellar ataxia (SCA) type 2 whose condition improved following treatment with Korean medicine. Methods: A 25-year-old man, diagnosed with SCA type 2, was treated with herbal medicine (Yukmijiwhang-tang-gami), acupuncture, and physical treatment. The therapeutic effect was evaluated using the Berg Balance Scale (BBS) and gait status. Results: Following treatment, the BBS score increased, and gait ataxia improved. Conclusions: This case study suggests that Korean medicine could be effective for relieving symptoms of SCA type 2.

Clinical Case Report of Spinocerebellar Ataxia Type 1 (제 1형 척수소뇌실조 환자의 증례보고)

  • Sun, Yung Chen;Jung, Woo Seok;Moon, Byung Soon;Yun, Jong Min
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.27 no.6
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    • pp.842-846
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    • 2013
  • The purpose of this study was to report one clinical case of spinocerebellar ataxia(SCA) type 1 improved by herbal medicine and oriental medical treatment. As a treatment, Yukmijihwang-tang(Liuweidihuangtang)-gamibang, acupuncture, and moxa were tried upon the patient for 21 days in order to relieve the symptoms. In terms of observing the changes of symptoms, the progress of patient's condition was evaluated periodically by using the Korean-mini mental state examination(K-MMSE), Modified Barthel Index(MBI), Functional Independence Measure(FIM). In accordance with the observation under K-MMSE, MBI, FIM, the patient's symptoms had gradually improved throughout the treatment. Therefore, this report suggests that Yukmijihwang-tang(Liuweidihuangtang)-gamibang, acupuncture and moxa were probably effective in the treatment of SCA type 1.

Combining ability and heterosis of Korean sorghum varieties

  • Choe, Myeongeun;Ko, Jeeyeon;Song, Seokbo;Park, Changhwan;Kwak, Doyeon
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.79-79
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    • 2017
  • Grain Sorghum varieties grown in Korea have low productivity and are constrained by the fact that farmers' choice of improved varieties is limited. Hybrid cultivars have been demonstrated to be more productive and food security than pure line varieties. However, There's no available hybrid cultivars and never planted before in Korea. This study was, therefore, conducted to determine combining ability of Korean landrace varieties and cultivar, the level of heterosis of experimental hybrids depending on environments. Two cytoplasmic male-sterile lines were crossed with six male-fertile lines in accordance with North Carolina II mating scheme to generate 12 experimental hybrids. The hybrids were evaluated in replicated row-column alpha designs at two sites in Texas and South Korea under on-season production conditions. For each trait, general combining ability (GCA) and specific combining ability (SCA) effects were estimated using the line-tester method of analysis. Results indicated significant differences among genotypes for both grain yield potential and secondary traits. Hybrids were predominant for grain yield, and displayed up to 127% heterosis of A03017 ${\times}$ Sodamchal in Korea. Positive GCA for yield was observed for Donganme, Hwanggeumchal and Jungmo4002 in Korea. Among them Jungmo4002 and Donganme had highly positive for yield (227.90 and 84.90 kg ha-1), while it showed negative GCA for yield in College station (-40.90, -189.60 kg ha-1). ATx630 ${\times}$ Sodamchal had the greatest SCA for yield (468.10 kg/ha) in College station but at South Korea its SCA effect was -302.40 kg/ha. A similar trend was observed, followed by A03017 ${\times}$ Donganme (SCA effect = 215 kg ha-1 at College station vs. -44.20 kg ha-1 at South Korea). At South Korea the greatest positive SCA effect for grain was observed in ATx630 ${\times}$ Jungmo4002 as 322.20 kg/ha. Both GCA and SCA effects significantly interacted with site effects demonstrating the need for region adaptation of potential cultivars and test for developing Korea suitable cultivar.

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Centralized Clustering Routing Based on Improved Sine Cosine Algorithm and Energy Balance in WSNs

  • Xiaoling, Guo;Xinghua, Sun;Ling, Li;Renjie, Wu;Meng, Liu
    • Journal of Information Processing Systems
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    • v.19 no.1
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    • pp.17-32
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    • 2023
  • Centralized hierarchical routing protocols are often used to solve the problems of uneven energy consumption and short network life in wireless sensor networks (WSNs). Clustering and cluster head election have become the focuses of WSNs. In this paper, an energy balanced clustering routing algorithm optimized by sine cosine algorithm (SCA) is proposed. Firstly, optimal cluster head number per round is determined according to surviving node, and the candidate cluster head set is formed by selecting high-energy node. Secondly, a random population with a certain scale is constructed to represent a group of cluster head selection scheme, and fitness function is designed according to inter-cluster distance. Thirdly, the SCA algorithm is improved by using monotone decreasing convex function, and then a certain number of iterations are carried out to select a group of individuals with the minimum fitness function value. From simulation experiments, the process from the first death node to 80% only needs about 30 rounds. This improved algorithm balances the energy consumption among nodes and avoids premature death of some nodes. And it greatly improves the energy utilization and extends the effective life of the whole network.

Comparative Analysis of ViSCa Platform-based Mobile Payment Service with other Cases (스마트카드 가상화(ViSCa) 플랫폼 기반 모바일 결제 서비스 제안 및 타 사례와의 비교분석)

  • Lee, June-Yeop;Lee, Kyoung-Jun
    • Journal of Intelligence and Information Systems
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    • v.20 no.2
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    • pp.163-178
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    • 2014
  • Following research proposes "Virtualization of Smart Cards (ViSCa)" which is a security system that aims to provide a multi-device platform for the deployment of services that require a strong security protocol, both for the access & authentication and execution of its applications and focuses on analyzing Virtualization of Smart Cards (ViSCa) platform-based mobile payment service by comparing with other similar cases. At the present day, the appearance of new ICT, the diffusion of new user devices (such as smartphones, tablet PC, and so on) and the growth of internet penetration rate are creating many world-shaking services yet in the most of these applications' private information has to be shared, which means that security breaches and illegal access to that information are real threats that have to be solved. Also mobile payment service is, one of the innovative services, has same issues which are real threats for users because mobile payment service sometimes requires user identification, an authentication procedure and confidential data sharing. Thus, an extra layer of security is needed in their communication and execution protocols. The Virtualization of Smart Cards (ViSCa), concept is a holistic approach and centralized management for a security system that pursues to provide a ubiquitous multi-device platform for the arrangement of mobile payment services that demand a powerful security protocol, both for the access & authentication and execution of its applications. In this sense, Virtualization of Smart Cards (ViSCa) offers full interoperability and full access from any user device without any loss of security. The concept prevents possible attacks by third parties, guaranteeing the confidentiality of personal data, bank accounts or private financial information. The Virtualization of Smart Cards (ViSCa) concept is split in two different phases: the execution of the user authentication protocol on the user device and the cloud architecture that executes the secure application. Thus, the secure service access is guaranteed at anytime, anywhere and through any device supporting previously required security mechanisms. The security level is improved by using virtualization technology in the cloud. This virtualization technology is used terminal virtualization to virtualize smart card hardware and thrive to manage virtualized smart cards as a whole, through mobile cloud technology in Virtualization of Smart Cards (ViSCa) platform-based mobile payment service. This entire process is referred to as Smart Card as a Service (SCaaS). Virtualization of Smart Cards (ViSCa) platform-based mobile payment service virtualizes smart card, which is used as payment mean, and loads it in to the mobile cloud. Authentication takes place through application and helps log on to mobile cloud and chooses one of virtualized smart card as a payment method. To decide the scope of the research, which is comparing Virtualization of Smart Cards (ViSCa) platform-based mobile payment service with other similar cases, we categorized the prior researches' mobile payment service groups into distinct feature and service type. Both groups store credit card's data in the mobile device and settle the payment process at the offline market. By the location where the electronic financial transaction information (data) is stored, the groups can be categorized into two main service types. First is "App Method" which loads the data in the server connected to the application. Second "Mobile Card Method" stores its data in the Integrated Circuit (IC) chip, which holds financial transaction data, which is inbuilt in the mobile device secure element (SE). Through prior researches on accept factors of mobile payment service and its market environment, we came up with six key factors of comparative analysis which are economic, generality, security, convenience(ease of use), applicability and efficiency. Within the chosen group, we compared and analyzed the selected cases and Virtualization of Smart Cards (ViSCa) platform-based mobile payment service.

The Performance Comparison of the ISCA and MSCA Algorithm for Adaptive Equalization (적응 등화를 위한 ISCA와 MSCA 알고리즘의 성능 비교)

  • Lim, Seung-Gag;Kang, Dae-Soo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.12 no.4
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    • pp.7-13
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    • 2012
  • The performance of blind equalization algorithm ISCA was compared with MSCA that is used for the minimization of the inter symbol interference which occurs in the time dispersive communication channel for digital transmission. Because of the non-linearities of a magnitude and phase transfer characteristics of a communication channel, the transmitting signal will be received that band limited and time dispersived. Therefore the distortion was compensated by using the self adaptive equalizer at the receiving side, then passing through the detector for the decision of "1" or "0". At this time the Constellation Dependent Constant is played an important role in the adaptive equalizer used on the receiver. In order to calculation of this constant, the ISCA and MSCA was used the second order statistics. The ISCA and MSCA which are possible to compensation of mensioned transfer function simulataneously, are improved the performance of original SCA algorithm and then was compared the performance by computer simulation. For this, the recovered constellation, residual isi and MSE was used, and a result of performance comparison, the ISCA algorithm has better than the MSCA in every performance index. But on the steady state of equalizer, the variation of performance due to the CME terms in the MSCA equalization algorithm was less than the ISCA, so MSCA has better stability.

The Middleware Extension for guaranteeing the Implementation-Independency between C++ and VHDL (SCA에서 C++/VHDL 구현 독립성을 보장하기 위한 미들웨어의 확장)

  • Bae, Myung-Nam;Lee, Byung-Bog;Park, Ae-Soon;Lee, In-Hwan;Kim, Nae-Soo
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.46 no.6
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    • pp.66-77
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    • 2009
  • In this paper, we propose a CORBA middleware extension which is suitable to SCA based communication environment. The extensions guarantee the components to interconnect others without consideration about its implementation way and enables the developers to easily achieve the performance improvements in comparison to the existing methodology. This extension includes the HAO, the IDL2VHDL compiler, and the improvement of ORBit. The HAO is ORB implemented in logic level and is limited the some function according to the characteristic of FPGA. In addition, the IDL2VHDL compiler provides the mapping from CORBA IDL to VHDL, the VHSIC hardware description language, and the additional procedures for processing the component. Finally, the improved ORBit, CORBA ORB on GPP, can be direct connecting with the HAO on FPGA.

Intranasal Immunization With Nanoparticles Containing an Orientia tsutsugamushi Protein Vaccine Candidate and a Polysorbitol Transporter Adjuvant Enhances Both Humoral and Cellular Immune Responses

  • Cheol Gyun Kim;Won Kyong Kim;Narae Kim;Young Jin Pyung;Da-Jeong Park;Jeong-Cheol Lee;Chong-Su Cho;Hyuk Chu;Cheol-Heui Yun
    • IMMUNE NETWORK
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    • v.23 no.6
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    • pp.47.1-47.16
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    • 2023
  • Scrub typhus, a mite-borne infectious disease, is caused by Orientia tsutsugamushi. Despite many attempts to develop a protective strategy, an effective preventive vaccine has not been developed. The identification of appropriate Ags that cover diverse antigenic strains and provide long-lasting immunity is a fundamental challenge in the development of a scrub typhus vaccine. We investigated whether this limitation could be overcome by harnessing the nanoparticle-forming polysorbitol transporter (PST) for an O. tsutsugamushi vaccine strategy. Two target proteins, 56-kDa type-specific Ag (TSA56) and surface cell Ag A (ScaA) were used as vaccine candidates. PST formed stable nano-size complexes with TSA56 (TSA56-PST) and ScaA (ScaA-PST); neither exhibited cytotoxicity. The formation of Ag-specific IgG2a, IgG2b, and IgA in mice was enhanced by intranasal vaccination with TSA56-PST or ScaA-PST. The vaccines containing PST induced Ag-specific proliferation of CD8+ and CD4+ T cells. Furthermore, the vaccines containing PST improved the mouse survival against O. tsutsugamushi infection. Collectively, the present study indicated that PST could enhance both Ag-specific humoral immunity and T cell response, which are essential to effectively confer protective immunity against O. tsutsugamushi infection. These findings suggest that PST has potential for use in an intranasal vaccination strategy.

The Clinical Study on Spinocerebellar Ataxia with Cerebellar Atrophy (Cerebellar Atrophy로 인해 유발된 Spinocerebellar Ataria 환아(患兒) 1례(例) 보고(報告))

  • Ha, Kwang-Su;Kim, Sun-Mi;Ha, Su-Yun;Song, In-Sun;Lee, Jeong-Lim
    • The Journal of Pediatrics of Korean Medicine
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    • v.19 no.2
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    • pp.41-50
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    • 2005
  • Objective : The autosomal dominent cerebellar ataxia(ADCA) is an unusal familial herediatary disorder that has been called olivopontoerebellar atrophy. Recently ADCA referred to as spinocerebellar ataxia(SCA) by molecular genetic characteristics. The purpose of this study is to focus on the improvement of clinical symptoms in SCA patient by oriental medical treatment. Materials & Methods : We experienced a case of the 6-year-old female patient with SCA and the MRI showed atrophy of cerebellum. The patient's chief symptoms come within the purview of five kinds of retardation and five kinds of flaccidity. We treated her with herb medicine (Yukmijihwang-tang gamibang), acupuncture, scalp acupuncture. After we measured the progress of general condition by MBI(Modified Bathel Index). Results : After oriental medical treatment, chief symptoms (ataxia, weakness of low extremities, dysarthria, etc.) and general condition were improved. Conclusion : We suggest that oriental medical therapy is effective to the possibility of treatment on SCA, but more clinical study and observation should be needed.

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Estimation of Greenhouse Damaged Area by Heavy Snowfall using GIS and Remote Sensing Technique (논문 - GIS/RS를 이용한 비닐하우스 폭설 피해지역 추출 기법 연구)

  • Kim, Saet-Byul;Shin, Hyung-Jin;Yun, Dong-Koun;Hong, Sung-Wook;Kim, Seong-Joon
    • KCID journal
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    • v.18 no.2
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    • pp.111-121
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    • 2011
  • This study is to estimate the possible damage area of greenhouse by heavy snowfall event using terra MODIS snow cover area (SCA) and the ground measured snowfall data (GMSD). For the 4 heavy snowfall events of January 2001, March 2004, December 2005 and January 2010, the areas exceeding the design criteria of snowfall depth for greenhouse breaking were extracted by coupling the MODIS SCA and GMSD. The main damaged regions were estimated as Gangwon province in 2001, Chungbuk and part of Gyeongbuk province in 2004, Jeonbuk and Jeonnam province in 2005, and Gangwon and part of Gyeonggi province in 2010 respectively. Comparing with the investigated number of greenhouse damaged data, the estimated areas reflected the statistical data except 2001. The 2001 greenhouse damages were caused by the high wind speed (35.7m/sec) together with snowfall. The results of this study can be improved if the design criteria of wind speed is added.

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