• The Journal of Korean Medicine
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• v.17 no.2 s.32
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• pp.88-99
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• 1996

Impotence is defined as a consistent inability to achieve or maintain penile erection that is adequate for completion of sexual intercourse. In oriental midicine, the chief cause of impotence is the decline of the fire from the gate of life, and in western medicine that is psycogenic and organic. Because of the increase aging people and psycologic stress that modern people get, impotence became common. This bibliographic study on impotence in the oriental and western medicine books has come to the following conclusions. 1. The main cause of impotence in the oriental medicine is the decline of the fire from the gate of life(命門火衰), followed by the deficiency of both heart and spleen(心脾兩虛), the depression of Liver energy(肝氣鬱結), and attack of blended wetness and heat to the lower wanner(濕熱下注). 2. The theraphics of impotence in oriental medicine are warming and strenghthening Kidney. softness of Liver energy, tonifying the Kidney to relieve mental strain, clear away the wetness-heat, and infairment of Heart and Spleen. 3. The prescriptions of impotence are Yugyeyum, Gyibitang, Soyosan, Sunjitang, and Yongdamsagantang. 4. In the western medicine, psycotherapy, medical therapy and surgical therapy are the major way to treat impotence.

• Korean Journal of Biological Psychiatry
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• v.5 no.2
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• pp.278-282
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• 1998

Various neurotransmitters have been proposed as possible mediators of penile erection. Especially, norepinephrine and serotonin might have a important role in sexual arousal and penile erection. And it could be hypothesized that the psychogenic impotence is associated with the depletion or imbalance of norepinephrine and serotonin from evidences, such as the symptomatic manifestation of depression and the antidepressantinduced sexual dysfunction. The authors investigates the association of norepienphrine and serotonin with psychogenic impotence. The psychogenic impotent group(PIG) consisted of twenty-three patients with psychogenic impotence and the controlled group(CG) consisted of twenty-seven patients without psychogenic impotence. PIG had no organic cause accounting for their erectile dysfunction. The Beck Depression Inventory(BDI) and the State-Trait Anxiety Inventory(STAI) were applied to each subject to assess mood, state anxiety(SA) and trait anxiety(TA). Plasma norepinephrine level from systemic blood and 5-hydroxyindoleacetic acid(HIAA) levels from 24-hours urine were measured in each subject. The mean score of BDI of PIG was significantly higher than that of CG(p=0.015). PIG had a tendency of higher TA compared with CG(p=0.054). And also SA was higher in PIG, but did not show significant difference(p=0.193). The level of norepinephrine was significantly lower in patient with psychogenic impotence(p=0.000). And the level of 24-hours urine 5-HIAA was lower in PIG but did not show significant difference(p=0.494). Although the authors did not exclude depressive disorders in PIG, the present findings suggest that psychogenic impotence might have higher depressive mood and trait anxiety, and be associated with the depletion of norepinephrine in systemic blood.

• The Korean Journal of Nuclear Medicine
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• v.23 no.2
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• pp.209-214
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• 1989

Yasculogenic impotence is produced by abnormalities of vascular blood supply or drainage, and is the most common cause of various organic impotences. An increasing awareness of vascular causes of impotence has resulted from development of various diagnostic tests, but precise measurement of penile blood flow is difficult. Radionuclide penogram has been introduced recently to diagnose vasculogenic impotence. Forty-one impotent patients and 12 normal men were studied with radionuclide erection penogram using Tc-99m pertechnetate and an intracavernous injection of papaverine. We defined arteriogenic impotence as arterial index less than 0.66, and venogenic impotence as venous index greater than 0.09. By this criteria, the false positive ratio in normal men was 17%, and the false negative ratio in radically cystectomized patients was 0%. Side effects were small purpura of the penile shaft and dull pain during injection of papaverine. The radionuclide erection penogram was noninvasive and gave a dynamic evaluation of the arterial supply, venous drainage, and blood flow in the corporeal bodies. This method should be considered as a valuable adjunct to evaluate patients with vasculogenic impotence.

• The Korean Journal of Pain
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• v.8 no.2
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• pp.336-340
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• 1995

Impairment of erectile function, although normally a benign disorder, has a profound impact on the well-being of many men. Penile erection is produced by a complex series of events involving cognition, peripheral sensory input, central and peripheral autonomic nervous events and hormonal vascular events. The multiplicity of potential determinants identified suggest that impotence does not inexorably accompany age, but it is an arugmented significantly modifiable paraaging phenomena. A 53 year old male patients developed sudden impotence. The patients did not respond to intracavernous injection of papaverine. This patient was successfuly treated with 4 repeated stellate ganglion blocks.

• Journal of Food Hygiene and Safety
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• v.29 no.2
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• pp.92-98
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• 2014

The safety of fake anti-impotence drugs (fake Viagra : 26 samples, fake Cialis : 25 samples) distributed in Gyeonggi province was studied by monitoring the concentrations of anti-impotence pharmaceutical ingredient and their analogues. The concentrations of anti-impotence pharmaceutical ingredient 4 specis and their analogues 17 specis were estimated using by HPLC/PDA, LC-MS/MS. The range of concentration of sildenafil in fake viagra was 40~199 mg/tablet, among them the portion of the concentrations of sildenafil over 150 mg/tablet exceeded 65%. 3 cases in tested samples contained sildenafil and tadalafil. The range of concentration of sildenafil in fake cialis was 102~249 mg/tablet, among them the portion of the concentrations of sildenafil over 150 mg/tablet exceeded 88%. One case in tested samples contained demethylhongdenafil (90 mg/tablet). These results indicate that there were many fake anti-impotence drug contained high level of anti-impotence pharmaceutical ingredients, a sustainable monitoring and the blocked distribution of fake anti-impotence drugs recommended.

• Clinical and Experimental Reproductive Medicine
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• v.13 no.2
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• pp.181-185
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• 1986

To estimate the penile blood flow changes during artificial with erection intracorporeal papaverine injection, we injected 99 m Technitium-Human Serum Albumin via antecubital vein simultaneously and calculate the radioisotope activity of the penis using computerized Gamma Camera. We classified the results into 3 groups according to the transit time, erection persistent time and venous index in 67 impotence patients. We defined the arteriogenic impotence with the delayed transit time (more than 600 seconds) in 13 patients and venogenic with the shortened erection persistant time (less than 200 seconds) and decreased venous index (less than 0.8) in 11 patients. The rest of them (43 patients) were regarded as equivocal impotence, probably nonvasculogenic or psychogenic.

• Analytical Science and Technology
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• v.21 no.2
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• pp.65-83
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• 2008

It is noted that illegal hazardous foods containing unauthorized drugs or synthetic drung analogues are increasing. Especially, reported are unknown compounds that have the modified chemical structures of the anti-impotence drugs such as sildenafil, vardenafil, and tatalafil. In addition, it is very reserved, since illegal synthetic compounds having similar chemical structures modified from anti-impotence drug to avoid the government inspection are not proved their safety at all. This review in ulation to food safety, lists the illegal compounds added to foods and describes about the analytical methods to chanacterize 16 anti-impotence drug analogues such as homosildenafil, hongdenafil, pseudovardenafil, aminotadalafil, hydroxyhomosildenafil, hydroxyhongdenafil, dimethylsildenafil, xanthoanthrafil, hydroxyvardenafil, norneosildenafil, demethylhongdenafil, piperidinohongdenafil, carbodenafil, thiosildenafil, dimethylthiosildenafil, and acetylvardenafil.

• The Korean Journal of Nuclear Medicine
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• v.28 no.3
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• pp.371-376
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• 1994

To reevaluate the clinical usefulness of erection penography for diffential diagnosis of impotence, we reviewed retrospectively the data of penography in 56 patients who were diagnosed as impotence by various diagnostic workup. Twelve normal males were studied as control group. Papaverine HCl 30mg was injected into the corpus cavernosum and simultaneously $^{99m}Tc$-HSA 20mCi was injected via an antecubital vein. After injection radioactivities in the penile area were detected for 30 minutes by gamma camera and time activity curve was displayed. We defined that transit time(TT) is the time to reach peak activity and erection persistent time(EPT) is the duration of time to maintain peak activity and venous index(VI) is the ratio of radioactivity($R_{30}/R_{max}$). The results were as follows. The TT of arteriogenic group($10.7{\pm}2.8min$) was significantly increased compared with those of control and venogenic groups(P<0.05, respectively). The EPT of venogenic group ($6.2{\pm}6.8min$) is significantly decreased compared with those of control and arteriogenic groups(P<0.05, respectively). The TT of psychogenic($15.2{\pm}5.5min$) is significantly increased compared with those of control and arteriogenic groups(P<0.05, respectively). In conclusion erection penography was very useful for the diagnosis of vascular and psychogenic impotence and for differentiation between arteriogenic and venogenic but it could not differentiate mixed type or neurogenic from vascular or psychogenic.

• SUVANNABHUMI
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• v.16 no.1
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• pp.147-173
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• 2024

Nguyễn Huy Thiệp is a pillar in Vietnamese cultural life after the Second Indochina War, and the fates of men and women at the beginning of Đổi mới (Renovation) is one of the prominent themes in his short stories. To show off sexual power, seek glory, and maintain his dominant position, Thiệp's heroes engage in a game of oppressing the weak, hunting animals, and harassing women. However, due to the complex changes in social life, moral values, and gender inequality, men in the postwar period quickly experienced the feeling of humiliation, impotence, and failure. In turn, the sophisticated aspects of masculinity demonstrate the cultural and ethical concerns of contemporary Vietnamese society. By exploring the multidimensional nature of masculinity expressed in Thiệp's stories, this study aims to resolve misconceptions about gender and the relationship between men and women in his work.

• Journal of environmental and Sanitary engineering
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• v.22 no.3
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• pp.89-96
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• 2007

To determine 8 anti-impotence drug/drug-like compounds such as sildenafil, vardenafil, tadalafil, homosildenafil, hydroxyhomosildenafil, aminotadalafil, pseudovardenafil and hongdenafil in foods, simultaneously, high performance liquid chromatography(HPLC) and liquid chromatography-mass spectrometry (LC/MS) were used. The HPLC/UV analysis was performed on a column of capcellpak $C_{18}$ with 0.1% sodium-1-hexansulfonate in 0.2M ammonium formate/acetonitrile as a mobile phase. Mass spectra of the compounds by LC/MS were investigated with SCAN mode(Mass range and Fragment voltage) and SIM(Selected Ion Monitoring) mode (Ion target and Fragment voltage). The results follow as; 1. The HPLC/UV analysis was detected from 5 out of 63 samples. The content of sildenafil was in the range of 32.80 ppm ${\sim}$ 60.13 ppm from 4 out of 5 samples. The contents of sildenafil, vardenafil, homosildenafil were in the range 47.14 ppm from 1 out of 5 samples. 2. The conformed result of LC/MS was equal of detected from 5 out of 63 samples in HPLC/UV analysis. An easily available, simultaneous determination of 8 standards in adulterated health related foods was established by using a combination of LC/MS methods.