• Title/Summary/Keyword: Impact pathway

Search Result 179, Processing Time 0.029 seconds

A Study of Leadership Competencies and Job Embeddedness among Child Group Home Workers : The Double Mediating Effects of Social Capital and Organizational Culture (아동 공동생활가정 종사자의 리더십 역량과 직무착근도 연구: 사회적자본과 조직문화의 이중 매개효과)

  • Goo, Hyeongyu;Kim, Bongwha
    • The Journal of the Convergence on Culture Technology
    • /
    • v.10 no.3
    • /
    • pp.593-604
    • /
    • 2024
  • This study examined the effect of leadership competence on job embeddedness among child co-residence workers to mitigate the negative impact of human resource management on their low job tenure and treatment. The study initially tested the mediating effects of social capital and organizational culture between the two variables, thereby suggesting ways to enhance job attendance among workers in children's shared family homes. The results of the study are as follows. Leadership competencies among child co-residence workers were found to have a positive effect not only on job embeddedness but also on social capital and organizational culture. Social capital and organizational culture were identified as mediators in the relationship between leadership competencies and job commitment The primary significance of this study lies in its identification of the relationship between leadership competence and job attendance - a factor previously overlooked. This finding offers a pathway to increase job attendance. Furthermore, the study expands the scope of relevant variables to include leadership competence, social capital, and organizational culture. Finally, it sheds light on the mediating effects of social capital and organizational culture on the relationship between leadership competence and job embeddedness.

Analysis of Domestic and Overseas Radioactive Waste Maritime Transportation and Dose Assessment for the Public by Sinking Accident (국내·외 방사성폐기물 해상운반 현황 및 침몰사고 시 일반인 선량평가 사례 분석)

  • Ga Eun Oh;Min Woo Kwak;Hyeok Jae Kim;Kwang Pyo Kim
    • Journal of Radiation Industry
    • /
    • v.18 no.1
    • /
    • pp.35-42
    • /
    • 2024
  • Demand for RW transportation is expected to increase due to the continuous generation of RW from nuclear power plants and facilities, decommissioning of plants, and saturation of spent fuel temporary storage facilities. The locational aspect of plants and radiation protection optimization for the public have led to an increasing demand for maritime transportation, necessitating to apprehend the overseas and domestic current status. Given the potential long-term radiological impact on the public in the event of a sinking accident, a pre-transportation exposure assessment is necessary. The objective of this study is to investigate the overseas and domestic RW maritime transportation current status and overseas dose assessment cases for the public in sinking accident. Selected countries, including Japan, UK, Sweden, and Korea, were examined for transport cases, Japan and the U.S were chosen for dose assessment case in sinking accidents. As a result of the maritime transportation case analysis, it was performed between nuclear power plants and reprocessing facilities, from plants to disposal or intermediate storage facilities. HLW and MOX fuel were transported using INF 3 shipments, and all transports were performed low speed of 13 kn or less. As a result of the dose assessment for the public in sinking accident, japan conducted an assessment for the sinking of spent fuel and vitrified HLW, and the U.S conducted for the sinking of spent fuel. Both countries considered external exposure through swimming and working at seashore, and internal exposure through seafood ingestion as exposure pathway. Additionally, Japan considered external exposure through working on board and fishing, and the U.S considered internal exposure through spray inhalation and desalinized water and salt ingestion. Internal exposure through seafood ingestion had the largest dose contribution. The average public exposure dose was 20 years after the sinking, 0.04 mSv yr-1 for spent fuel and 5 years after the sinking, 0.03 mSv yr-1 for vitrified HLW in Japan. In the U.S, it was 1.81 mSv yr-1 5 years after the sinking of spent fuel. The results of this study will be used as fundamental data for maritime transportation of domestic RW in the future.

A study on the diversification of Interpretation according to the Bible didactics by Horst Klaus Berg (Horst Klaus Berg의 성서교수학에 나타난 해석 다양성에 관한 연구)

  • Jeongdo An
    • Journal of Christian Education in Korea
    • /
    • v.77
    • /
    • pp.127-150
    • /
    • 2024
  • This study seeks to shed light on the contributions of Horst Klaus Berg to German Bible didactics, underscoring the pivotal role of diverse interpretative approaches in the teaching and learning of the Bible. In an era where the complexities and intricacies of the Bible present significant challenges to contemporary readers, the prevalence of one-dimensional interpretations further obstructs the pathway to a profound comprehension of the spiritual depth embedded within its texts. By centering on Horst Klaus Berg's influential theories in the field of German Bible didactics, this research delves into the impact of varied biblical interpretations on Christian education. Berg's work is celebrated for its insightful strategies, notably his advocacy for comprehensive interpretative methods such as "Railway Tracks" and "Free-Learning." These approaches seek to reconcile traditional biblical teachings with individual experiences, thereby facilitating a more expansive understanding of the Bible's applicability to modern life. Through a detailed examination of Berg's theory on biblical interpretation, this paper argues that Christian education must prioritize the cultivation of diverse interpretative skills and their practical integration into Bible study. This educational model encourages learners to become active interpreters, capable of discerning the text's deep-seated meanings by relating it to their personal experiences. The study concludes by affirming Berg's delineation of three critical tasks in biblical interpretation: "reciprocal interpretation," "acknowledgment of the biblical texts' diversity," and "free learning." These elements are portrayed as interrelated and essential, reinforcing Berg's proposition that understanding the Bible's complexity and diversity is crucial for advancing Christian education. This paper offers a novel perspective on the significance of embracing multifaceted interpretations within the domain of biblical studies.

Protective effect of Evodiae Fructus extract in HCl/ethanol-induced gastritis mice (HCl/ethanol로 유도된 위염 마우스 모델에서 오수유 추출물의 보호 효과)

  • IL-Ha Jeong;Mi-Rae Shin;Min Ju Kim;Hui Yeon An;Seong-Soo Roh
    • Journal of Nutrition and Health
    • /
    • v.57 no.4
    • /
    • pp.403-417
    • /
    • 2024
  • Purpose: This study investigated the anti-inflammatory effects of Evodiae Fructus (EF) on hydrochloric acid (HCl)/ethanol-induced gastritis, focusing on its impact on oxidative stress by analyzing inflammatory cytokines and inflammation-related factors. The total polyphenol and flavonoid contents were determined through in vitro experiments, while the radical scavenging activity was confirmed using 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) assays. Methods: In vivo experiments were conducted on rats divided into 5 groups (n = 7/in each group): normal group (Normal), 150 mM HCl/60% ethanol-induced gastritis group (Control), 150 mM HCl/60% ethanol-induced gastritis group administered 10 mg/kg sucralfate (SC), 150 mM HCl/60% ethanol-induced gastritis group administered EF at the doses of 100 mg/kg or 200 mg/kg (EF100 or EF200). The mice were pretreated with the extract (EF) or drug (SC), and after 1 hour, 150 mM HCl/60% ethanol (v/v) mixture was administered orally. Reactive oxygen species (ROS) levels, peroxynitrite (ONOO-), and pro-inflammatory cytokines including tumor necrosis factor-α and interleukin-1 beta were assessed in serum. Additionally, western blotting of the gastric tissues confirmed the expression of inflammation-related proteins. Results: EF alleviated the gastric mucosal damage caused by 150 mM HCl/60% ethanol. The assessment of oxidative stress in the serum showed that EF significantly reduced ROS and ONOO- levels and significantly decreased the levels of pro-inflammatory cytokines. Western blot analysis revealed that EF reduced ROS-generating nicotinamide adenine dinucleotide phosphate oxidase subunits, including gp91phox, p22phox, and p47phox. Additionally, EF mitigated the inflammation by inhibiting the mitogen-activated protein kinase signaling pathway. Conclusion: These results indicate that EF is a potential herbal medicine candidate for the treatment of oxidative stress-induced gastritis.

Comparison of Human Health Risk Assessment of Heavy Metal Contamination from Two Abandoned Metal Mines Using Metal Mine-specific Exposure Parameters (국내 폐금속 광산에 특화된 노출인자를 이용한 두 폐금속 광산 중금속 오염에 대한 인체위해성평가 비교)

  • Lim, Tae-Yong;Lee, Sang-Woo;Cho, Hyen Goo;Kim, Soon-Oh
    • Journal of Environmental Impact Assessment
    • /
    • v.25 no.6
    • /
    • pp.414-431
    • /
    • 2016
  • There are numerous closed and abandoned mines in Korea, from which diverse heavy metals (e.g., As, Cd, Cu, Pb, Zn) are released into the surrounding soil, groundwater, surface water, and crops, potentially resulting in detrimental effects on the health of nearby residents. Therefore, we performed human risk assessments of two abandoned metal mines, Yanggok (YG) and Samsanjeil (SJ). The exposure parameters used in this assessment were specific to residents near mines and the included exposure pathways were relevant to areas around metal mines. The computed total excess carcinogenic risks for both areas exceeded the acceptable carcinogenic risk ($1{\times}10^{-6}$), indicating that these areas are likely unsafe due to a carcinogenic hazard. In contrast, the non-carcinogenic risks of the two areas differed among the studied receptors. The hazard indices were higher than the unit risk (=1.0) for male and female adults in YG and male adults in SJ, suggesting that there are non-carcinogenic risks for these groups in the study areas. However, the hazard indices for children in YG and female adults and children in SJ were lower than the unit risk. Consumption of groundwater and crops grown in the area were identified as major exposure pathways for carcinogenic and non-carcinogenic hazards in both areas. Finally, the dominant metals contributing to carcinogenic and non-carcinogenic risks were As and As, Cu, and Pb, respectively. In addition, the carcinogenic and non-carcinogenic risks of YG were evaluated to be 10 and 4 times higher than those of SJ, respectively, resulted from the relatively higher exposure concentration of As in groundwater within SJ area. Because of lacking of several exposure parameters, some of average daily dose (ADD) could not be computed in this study. Furthermore, it is likely that the ADDs of crop-intake pathway included some errors because they were calculated using soil exposure concentrations and bioconcentration factor (BCF) rather than using crop exposure concentrations.

Exposure and Risk Assessments of Multimedia of Arsenic in the Environment (환경 중 비소의 매체통합 노출평가 및 위해성평가 연구)

  • Sim, Ki-Tae;Kim, Dong-Hoon;Lee, Jaewoo;Lee, Chae-Hong;Park, Soyeon;Seok, Kwang-Seol;Kim, Younghee
    • Journal of Environmental Impact Assessment
    • /
    • v.28 no.2
    • /
    • pp.152-168
    • /
    • 2019
  • The element arsenic, which is abundant in the Earth's crust, is used for various industrial purposes including materials for disease treatment and household goods. Various human activities, such as the disposal of soil waste, metal mining and smelting, and combustion of fossil fuels, have caused the pollution of the environment with arsenic. Recently, guidelines for arsenic in rice have been adopted by the Korean ministry of food and drug safety to prevent health risks based on rice consumption. Because of the exposure to arsenic and its accumulation in the human body through various channels, such as air inhalation, skin contact, ingestion of drinking water, and food consumption, integrated multimedia risk assessment is required to adopt appropriate risk management policies. Therefore, integrated human health risk assessment was carried out in this study using integrated exposure assessment based on multimedia (e.g., air, water, and soil) and multi-route (e.g., oral, inhalation, and dermal) scenarios. The results show that oral uptake via drinking water is the most common pathway of arsenic into the human body, accounting for 57%-96% of the total arsenic exposure. Among various age groups, the highest exposures to arsenic were observed in infants because the body weight of infants is low and the surface areas of infant bodies are large. Based on the results of the exposure assessment, the cancer and non-cancer risks were calculated. The cancer risk for CTE and RME is in the range of 2.3E-05 to 6.7E-05 and thus is negligible because it does not exceed the cancer probability of 1.0E-04 for all age groups. On the other hand, the cancer risk for RME varies from 6.4E-05 to 1.8E-04 and from 1.3E-04 to 1.8E-04 for infants and preschool children, exceeding the excess cancer risk of 1.0E-04. The non-cancer risks range from 5.4E-02 to 1.9E-01 and from 1.5E-01 to 6.8E-01, respectively. They do not exceed the hazard index 1 for all scenarios and all ages.

Development Strategy for New Climate Change Scenarios based on RCP (온실가스 시나리오 RCP에 대한 새로운 기후변화 시나리오 개발 전략)

  • Baek, Hee-Jeong;Cho, ChunHo;Kwon, Won-Tae;Kim, Seong-Kyoun;Cho, Joo-Young;Kim, Yeongsin
    • Journal of Climate Change Research
    • /
    • v.2 no.1
    • /
    • pp.55-68
    • /
    • 2011
  • The Intergovernmental Panel on Climate Change(IPCC) has identified the causes of climate change and come up with measures to address it at the global level. Its key component of the work involves developing and assessing future climate change scenarios. The IPCC Expert Meeting in September 2007 identified a new greenhouse gas concentration scenario "Representative Concentration Pathway(RCP)" and established the framework and development schedules for Climate Modeling (CM), Integrated Assessment Modeling(IAM), Impact Adaptation Vulnerability(IAV) community for the fifth IPCC Assessment Reports while 130 researchers and users took part in. The CM community at the IPCC Expert Meeting in September 2008, agreed on a new set of coordinated climate model experiments, the phase five of the Coupled Model Intercomparison Project(CMIP5), which consists of more than 30 standardized experiment protocols for the shortterm and long-term time scales, in order to enhance understanding on climate change for the IPCC AR5 and to develop climate change scenarios and to address major issues raised at the IPCC AR4. Since early 2009, fourteen countries including the Korea have been carrying out CMIP5-related projects. Withe increasing interest on climate change, in 2009 the COdinated Regional Downscaling EXperiment(CORDEX) has been launched to generate regional and local level information on climate change. The National Institute of Meteorological Research(NIMR) under the Korea Meteorological Administration (KMA) has contributed to the IPCC AR4 by developing climate change scenarios based on IPCC SRES using ECHO-G and embarked on crafting national scenarios for climate change as well as RCP-based global ones by engaging in international projects such as CMIP5 and CORDEX. NIMR/KMA will make a contribution to drawing the IPCC AR5 and will develop national climate change scenarios reflecting geographical factors, local climate characteristics and user needs and provide them to national IAV and IAM communites to assess future regional climate impacts and take action.

Validation of Learning Progressions for Earth's Motion and Solar System in Elementary grades: Focusing on Construct Validity and Consequential Validity (초등학생의 지구의 운동과 태양계 학습 발달과정의 타당성 검증: 구인 타당도 및 결과 타당도를 중심으로)

  • Lee, Kiyoung;Maeng, Seungho;Park, Young-Shin;Lee, Jeong-A;Oh, Hyunseok
    • Journal of The Korean Association For Science Education
    • /
    • v.36 no.1
    • /
    • pp.177-190
    • /
    • 2016
  • The purpose of this study is to validate learning progressions for Earth's motion and solar system from two different perspectives of validity. One is construct validity, that is whether a hypothetical pathway derived from our study of LPs is supported by empirical evidence of children's substantive development. The other is consequential validity, which refers to the impact of LP-based adaptive instruction on children's improved learning outcomes. For this purpose, 373 fifth-grade students and 17 teachers from six elementary schools in Seoul, Kangwon province, and Gwangju participated. We designed LP-based adaptive instruction modules delving into the unit of 'Solar system and stars.' We also employed 13 ordered multiple-choice items and analyzed the transitions of children's achievement levels based on the results of pre-test and post-test. For testing construct validity, 64 % of children in the experimental group showed improvement according to the hypothetical pathways. Rasch analysis also supports this results. For testing consequential validity, the analysis of covariance between experimental and control groups revealed that the improvement of experimental group is significantly higher than the control group (F=30.819, p=0.000), and positive transitions of children's achievement level in the experimental group are more dominant than in the control group. In addition, the findings of applying Rasch model reveal that the improvement of students' ability in the experimental group is significantly higher than that of the control group (F=11.632, p=0.001).

Toll-like Receptor 4-mediated Apoptotic Cell Death in Primary Isolated Human Cervical Cancers (부인과질환 특이적 종양의 TLR4 매개성 apoptosis 유발에 관한 연구)

  • Won, Jinyoung;Hong, Yunkyung;Park, Sookyoung;Kim, Joo-Heon;Hong, Yonggeun
    • Journal of Life Science
    • /
    • v.28 no.6
    • /
    • pp.718-725
    • /
    • 2018
  • Toll-like receptor 4 (TLR4) has been implicated in cell proliferation and apoptosis in several types of cancer. In this study, the impact of TLR4 activation on apoptotic cell death in gynecologic cancers induced by lipopolysaccharide (LPS) was investigated. Cervical cancer cell lines were produced from isolated surgical specimens supplied by Paik Hospital. The primary cultures of normal myometrium and gynecologic cancers, including cervical, endometrial, and ovarian cancers, were used to examine the differences in morphological characteristics between normal and cancerous cells. A reverse transcription polymerase chain reaction analysis was used to determine the relative expression levels of TLR4 gene involved in apoptosis-associated signaling in cervical cancer cells. The cancer cell colonies showed a tendency to reach high levels of confluency compared with normal cells. In addition, an enhanced growth rate and loss of contact inhibition were observed in gynecologic cancer cells compared with normal cells (doubling times of 16.6 hr vs. 26 hr, respectively). The expression level of ITGA5, an alpha-5 integrin marker, was upregulated in normal myometrial cells, but this tendency was not exhibited in cervical cancer cells. Furthermore, p53 tumor suppressor gene expression was upregulated, whereas TLR4 and caspase-3 gene expressions were downregulated in cervical cancer cells. Notably, the expression levels of TLR4 and caspase-3 were increased significantly in LPS-treated cancer cells compared with those in non-LPS-treated cells. These results suggest that the TLR4-mediated caspase-dependent apoptotic signaling pathway could be suggested as a therapeutic target for the treatment of gynecologic cancers, including cervical cancers.

Environmental and Ecological Consequences of Submarine Groundwater Discharge in the Coastal Areas of the Korea Peninsula (한반도 연안 해역에서 해저 지하수 유출의 환경 생태학적 중요성)

  • KIM GUEBUEM;HWANG DONG-WOON;RYU JAE-WOONG;LEE YONG-WOO
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
    • /
    • v.10 no.4
    • /
    • pp.204-212
    • /
    • 2005
  • Recognition has emerged that nutrient inputs from the submarine discharge of fresh, brackish, and marine groundwaters into the coastal ocean are comparable to the inputs via river discharge. The coastal areas of the Korea peninsula and adjacent seas exhibit particular importance in the role of submarine groundwater discharge (SGD), in terms of the magnitude of SGD and associated continental material fluxes. For example, in the southern sea of Korea, SGD transports excess nutrients into the coastal regions and thus appears to influence ecosystem changes such as the outbreak of red tides. Around volcanic island, Jeju, which is composed of high permeability rocks, the amount of SGD is higher by orders of magnitude relative to the eastern coast of North America where extensive SGD studies have been conducted. In particular, nutrient discharge through SGD exerts a significant control on coastal ecosystem changes and results in benthic eutrophication in semi-enclosed Bang-du bay, Jeju. In the entire area of the Yellow Sea, tile submarine discharge of brackish groundwater and associated nutrients are found to rival the river discharges into the Yellow Sea, including those through Yangtze River, Han River, etc. In the eastern coast of the Korea peninsula, SGD is significantly higher during summer than winter due to high hydraulic gradients and due to wide distribution of high permeability sandy zones, faults, and fractures. On the other hand, in the estuarine water, downstream construction of the dam in the Nakdong River, SGD was highest when the river discharge was lowest (but water level of the dam was highest). This suggests that even though there is no visible freshwater discharge into this estuary, the discharge of chemical species is significant through SGD. On the basis of the results obtained from the coastal areas of the Korea peninsula, SGD is considered to be an important pathway of continental contaminants influencing tidal-flat ecosystems, red tides, and coral ecology. Thus, future costal management should pay great attention to the impact of SGD on coastal pollution and eutrophication.