• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.19 no.4
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• pp.291-298
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• 2007

The purpose of this study is to evaluate the efficacy of multizone simulation that enables to grasp of details about microbial contaminant problem in an multistoried apartment. We used actual indoor test data to figure up microbial contaminant level as initial value for the multizone simulation and estimated the various effects of indoor occupant infected with germs such as bacteria and fungus and the performance of air sterilization by using multizone simulation in substitute for infeasible experimental approach. The results show that natural ventilation make ourselves generally useful for removing indoor microbial contaminants. The results also show that the performance of air sterilization reach the maximum in the case of using mechanical ventilation and UVGI air sterilizer. The conclusion is that this multizone simulation is useful tool for actual design method for immune building systems.

• Journal of the Korean Society for Nondestructive Testing
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• v.26 no.6
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• pp.373-379
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• 2006

Vibration-based structural health monitoring is one of non-destructive evaluation (NDE) techniques for civil infrastructures. This paper presents a novel fiber optic accelerometer system to monitor civil engineering structures and a successful application of the novel sensor system for measuring ambient vibration of a real building structure. This sensor system integrates the Moire fringe phenomenon with fiber optics to achieve accurate and reliable measurements. The sensor system is immune to electromagnetic (EM) interference making it suitable for difficult applications in such environments involving strong EM fields, electrical spark-induced explosion risks, and cabling problems, prohibiting the use of conventional electromagnetic accelerometers. A prototype sensor system has been developed, together with a signal processing software. The experimental studies demonstrated the high-performance of the fiber optic sensor system. Especially, the sensor was successfully used for monitoring a real building on UCI (University of California Irvine, USA).

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.21 no.1
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• pp.63-70
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• 2009

The air sterilization systems are investigated experimentally in this paper. The goal is to reduce bacteria, mold and viruses in office air by using a UV sterilizer installed inside a partition panel and wall-mounted unit. These systems allow occupants to turn the system on/off and to control the incoming air speed and direction. The partition air sterilization system conditions and sterilizes the air, and then delivers the clean air into the personal task area through the partition panels, which are connected to the pressurized under-floor plenum. Room air exits through the return grills mounted on the ceiling. The wall-mounted air sterilization system sterilizes the air, and then delivers the clean air to the personal task area from the wall. In this study a full-size experimental environment is established to investigate the immunization performance of these air sterilization systems. A typical office space scale is used in this study in order to find an optimal system to achieve a sterilized healthy micro-environment. Multiple system parameters, including volume flow rate and velocity of supplied air, were regulated during the experiments. The more air contact these air sterilization systems had, the better disinfection performance. Over 90% of eradication ratios were obtained by these two air sterilization systems. The results indicate that these systems can efficiently disinfect office air contamination.

• Journal of Korean Port Research
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• v.11 no.2
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• pp.273-280
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• 1997

Recently the importance of the cargo handling equipments in a port has been increasing to get strong competition from other ports. Many ports are making efforts to modernize their cargo handling equipments. The kernel technology of such equipments is the speed control of DC motor which is used as an essential part of them. In this paper, we discuss the speed control of a DC motor as a basic work for building cargo handling equipments in a port. DC Motors are still widely used in industrial fields, as driving power motor for electrical fields. DC drives, being easy to control, are widely used in many variable-speed and position control drive system. Traditional analog control circuits used in such applications have many disadvantages. Complex control schemes are difficult to implement with analog components. All these factor and invention of the microprocessor has made it possible to use digital control circuits, using microprocessing system. These digital circuits have been found to be reliable, flexible, and also immune to noise. In this paper it presents the speed control of a SCR DC motor driver which using dual converter by 80c196kc microprocessor. We developed a thyristor power amplifier which does not cause damage thyristor because it is designed to prevent triggering the two SCRs in the same arm simultaneously. And it was analyzed voltage and currents wave at reactive load.

• Structural Engineering and Mechanics
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• v.52 no.2
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• pp.275-290
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• 2014

In this paper, Simple Adaptive Control (SAC) method is used to mitigate the detrimental effects of earthquakes on MR-damper equipped structures. Acceleration Feedback (AF) is utilized since measuring the acceleration response of structures is known to be reliable and inexpensive. The SAC is simple, fast and as an adaptive control scheme, is immune against the effects of plant and environmental uncertainties. In the present study, in order to translate the desired control force into an applicable MR damper command voltage, a neural network inverse model is trained, validated and used through the simulations. The effectiveness of the proposed AF-based SAC control system is compared with optimal H2/LQG controllers through numerical investigation of a three-story model building. The results indicate that the SAC controller is substantially effective and reliable in both undamaged and damaged structural states, specifically in reducing acceleration responses of seismically excited buildings.

• BMB Reports
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• v.53 no.1
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• pp.28-34
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• 2020

Sphingolipids are ubiquitous building blocks of eukaryotic cell membranes that function as signaling molecules for regulating a diverse range of cellular processes, including cell proliferation, growth, survival, immune-cell trafficking, vascular and epithelial integrity, and inflammation. Recently, several studies have highlighted the pivotal role of sphingolipids in neuroinflammatory regulation. Sphingolipids have multiple functions, including induction of the expression of various inflammatory mediators and regulation of neuroinflammation by directly effecting the cells of the central nervous system. Accumulating evidence points to sphingolipid engagement in neuroinflammatory disorders, including Alzheimer's and Parkinson's diseases. Abnormal sphingolipid alterations, which involves an increase in ceramide and a decrease in sphingosine kinase, are observed during neuroinflammatory disease. These trends are observed early during disease development, and thus highlight the potential of sphingolipids as a new therapeutic and diagnostic target for neuroinflammatory diseases.

• Smart Structures and Systems
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• v.4 no.2
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• pp.195-208
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• 2008

This paper summarizes the experimental vibration-based structural health monitoring study on a historical monument in Jordan. In this work, and within the framework of the European Commission funded project "wide-Range Non-Intrusive Devices Toward Conservation of Historical Monuments in the Mediterranean Area", a seven and a half century old minaret located in Ajloun (73 km north of the capital Amman) is studied. Because of their cultural value, touristic importance and the desire to preserve them for the future, only non-destructive tests were allowed for the experimental investigation of such heritage structures. Therefore, after dimensional measurements and determination of the current state of damage in the selected monument, ambient vibration tests are conducted to measure the accelerations at strategic locations of the system. Output-only modal identification technique is applied to extract the modal parameters such as natural frequencies and mode shapes. A Non-linear version of SAP 2000 computer program is used to develop a three-dimensional finite element model of the minaret. The developed numerical model is then updated according to the modal parameters obtained experimentally by the ambient-vibration test-results and the measured characteristics of old stone and deteriorated mortar. Moreover, a parametric identification method using the N4Sid state space model is employed to model the dynamic behavior of the minaret and to build up a robust, immune and noise tolerant model.

• Archives of Pharmacal Research
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• v.27 no.1
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• pp.118-126
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• 2004

The aqueous extract of European mistletoe (Viscum album, L.) has been used in cancer therapy. The purified mistletoe lectins, main components of mistletoe, have demonstrated cytotoxic and immune-system-stimulating activities. Korean mistletoe (Viscum album L. coloratum), a subspecies of European mistletoe, has also been reported to possess anticancer and immunological activities. A galactose- and N-acetyl-D-galactosamine-specific lectin (Viscum album L. coloratum agglutinin, VCA) with Mr 60 kDa was isolated from Korean mistletoe. Mistletoe preparations have been given subcutaneously due to the low stability of lectin in the gastrointestinal (GI) tract. In the present study, we investigated the possibility of alginate/chitosan microcapsules as a tool for oral delivery of mistletoe lectin. In addition, our strategy has been to develop a system composed of stabilizing cores (granules), which contain mistletoe lectin, extract or powder, coated by a biodegradable polymer wall. Our results indicated that successful incorporation of VCA into alginate/chitosan microcapsules has been achieved and that the alginate/chitosan microcapsule protected the VCA from degradation at acidic pH values. And coating the VCA with polyacrylic polymers, Eudragit, produced outstanding results with ideal release profiles and only minimal losses of cytotoxicity after manufacturing step. The granules prepared with extract or whole plant produced the best results due to the stability in the extract or whole plant during manufacturing process.

• Journal of Korean Traditional Oncology
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• v.19 no.1
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• pp.1-24
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• 2014

Objectives : The purpose of this study was to present the clinical guidelines for gastric cancer. Methods : The literature on Western and Oriental medical treatment of gastric cancer were collected, analyzed and summarized from the Google Scholar, KIOM OASIS and PUBMED from 1993 to 2014. Results : Gastric cancer is the second most common cancer in Korea. In recent studies, applying integrative oriental and western medicine can suppress the tumor, improve the survival, the immune system, and the quality of life in gastric cancer. But there isn't still a unified protocol for gastric cancer treatment, so we have difficulty in clinical application. This study will be helpful for understanding and building systems for integrative gastric cancer treatment. Conclusion : Further studies on integrative gastric cancer treatment are needed to improve the survival of gastric cancer patients and build the clinical practice guidelines of gastric cancer.

• Earthquakes and Structures
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• v.5 no.3
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• pp.297-319
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• 2013

Two destructive earthquakes occurred on October 23 and November 9, 2011 in Van province of Turkey. The damage in residential units shows significant deviation from the expectation of decreasing damage with increasing distance to epicenter. The most damaged settlement Ercis has the same distance to the epicenter with Muradiye, where no damage occurred while relatively less damage observed in Van having half distance. These three cities seem to have resembling soil conditions. If the damages are evaluated: joint failures and insufficient lap splice lengths are observed to be the main causes of the total collapses in RC buildings. Additionally, low concrete strength, reinforcement detailing mistakes, soft story, heavy overhang, pounding and short columns are among other damage reasons. Examples of damages due to non-structural elements are also given. Remarkable points about seismic damages are: collapsed buildings with shear-walls, heavily damaged buildings despite adequate concrete strength due to detailing mistakes, undamaged two-story adobe buildings close to totally collapsed RC ones and undamaged structural system in buildings with heavily damaged non-structural elements. On the contrary of the common belief that buildings with shear-walls are immune to total collapse among civil engineers, collapse of Gedikbulak primary school is a noteworthy example.