• Title, Summary, Keyword: Imaging Process

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Importance of Volumetric Measurement Processes in Oncology Imaging Trials for Screening and Evaluation of Tumors as Per Response Evaluation Criteria in Solid Tumors

  • Vemuri, Ravi Chandra;Jarecha, Rudresh;Hwi, Kim Kah;Gundamaraju, Rohit;MaruthiKanth, Aripaka;Kulkarni, AravindRao;Reddy, Sundeep
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.5
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    • pp.2375-2378
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    • 2014
  • Cancer, like any disease, is a pathologic biological process. Drugs are designed to interfere with the pathologic process and should therefore also be validated using a functional screening method directed at these processes. Screening for cancers at an appropriate time and also evaluating results is also very important. Volumetric measurement helps in better screening and evaluation of tumors. Volumetry is a process of quantification of the tumors by identification (pre-cancerous or target lesion) and measurement. Volumetric image analysis allows an accurate, precise, sensitive, and medically valuable assessment of tumor response. It also helps in identifying possible outcomes such disease progression (PD) or complete response as per Response Evaluation Criteria in Solid Tumors (RECIST).

Image Enhancement Algorithm in Imaging Systems for Electronic Photography (전자사진용 화상시스템의 화상개선 알고리즘)

  • 박용주;김지홍
    • Journal of the Korean Printing Society
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    • v.20 no.1
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    • pp.133-145
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    • 2002
  • A study on electronic imaging system with silver halide photography emulation by a parametric approach will be introduced. The study contains the comparison analysis between silver halide imaging process and electronic imaging process, the characterization of the detailed process in those imaging chains, such as exposure, developing, photographic print and the other photographic and digital process. We investigated the characteristic curve between optical density and the amount of exposure in silver halide and digital photography systems. Under wide range of exposure condition, several sensitometric parameters were obtained via studio and outdoor photographic experiments with conventional photography and a digital camera. whose experimental results will be shown. Finally, the comparison between electronic imaging and conventional photography via silver halide photography emulation and modeling the silver halide process wi13 be discussed.

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Development of Electron Beam Monte Carlo Simulation and Analysis of SEM Imaging Characteristics (전자빔 몬테 카를로 시물레이션 프로그램 개발 및 전자현미경 이미징 특성 분석)

  • Kim, Heung-Bae
    • Journal of the Korean Society for Precision Engineering
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    • v.29 no.5
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    • pp.554-562
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    • 2012
  • Processing of Scanning electron microscope imaging has been analyzed in both secondary electron (SE) imaging and backscattered electron (BSE) image. Because of unique characteristics of both secondary electron and backscattered electron image, mechanism of imaging process and image quality are quite different each other. For the sake of characterize imaging process, Monte Carlo simulation code have been developed. It simulates electron penetration and depth profile in certain material. In addition, secondary electron and backscattered electron generation process as well as their spatial distribution and energy characteristics can be simulated. Geometries that has fundamental feature have been imaged using the developed Monte Carlo code. Two, SE and BSE images generation process will be discussed. BSE imaging process can be readily used to discriminate in both material and geometry by simply changing position and direction of BSE detector. The developed MC code could be useful to design BSE detector and their position. Furthermore, surface reconstruction technique is possibly developed at the further research efforts. Basics of Monte Carlo simulation method will be discussed as well as characteristics of SE and BSE images.

In Vivo Visualization of Flow in Xylem Vessels of a Bamboo Using X-ray Micro-imaging Technique (X-ray 미세영상기법을 이용한 식물 목질부 내부 수액 유동의 계측)

  • Kim, Yang-Min;Lee, Sang-Joon
    • Proceedings of the KSME Conference
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    • pp.1693-1696
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    • 2004
  • Synchrotron X-ray micro-imaging technique was employed to monitor non-invasively the refilling process of water inside the xylem vessels in bamboo leaves. The consecutive phase-contrast X-ray images clearly show both plant anatomy and the transport of water inside the xylem vessels. Traces of water-rise, vapor bubbles and variations of contact angle between the water front and the xylem wall were measured in real time. During the refilling process, air bubbles are removed when the rising water front halts at a vessel end for a while. Subsequently, it starts rising again at a higher velocity than the normal refilling speed. Repeated cavitation seems to deteriorate the refilling ability in xylem vessels. In dark environment, the water refilling process in xylem vessels is facilitated more effectively than in bright illuminated conditions. Finally, X-ray micro-imaging was famed to be a powerful, high resolution, real time imaging tool to investigate the water refilling process in xylem vessels.

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Nuclear Medicine Imaging Instrumentations for Molecular Imaging (분자영상 획득을 위한 핵의학 영상기기)

  • Chung, Yong-Hyun;Song, Tae-Yong;Choi, Yong
    • The Korean Journal of Nuclear Medicine
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    • v.38 no.2
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    • pp.131-139
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    • 2004
  • Small animal models are extensively utilized in the study of biomedical sciences. Current animal experiments and analysis are largely restricted to in vitro measurements and need to sacrifice animals to perform tissue or molecular analysis. This prevents researchers from observing in vivo the natural evolution of the process under study. Imaging techniques can provide repeatedly in vivo anatomic and molecular information noninvasively. Small animal imaging systems have been developed to assess biological process in experimental animals and increasingly employed in the field of molecular imaging studies. This review outlines the current developments in nuclear medicine imaging instrumentations including fused multi-modality imaging systems for small animal imaging.

A Study of Simulacre Expression in Fashion Illustrations, Using Lenticular Technique (렌티큘러 기법을 활용한 패션일러스트레이션의 시뮬라크르적 표현 연구)

  • Lee, Jee-Hyun
    • Journal of the Korean Society of Costume
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    • v.59 no.8
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    • pp.152-165
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    • 2009
  • The purpose of this study was to expand the expression of Fashion Illustration using Lenticular imaging process. In the 2-dimensional pictures, Lenticular imaging process can be effective to make multiple, virtual and variable images, which are assumed the main characteristics of modern Fashion Illustration. For this study, the main characteristics of digital based fashion trend and Fashion Illustration were analyzed. The main characteristics of digital based fashion were 'Interaction, Variableness, Virtuality, Multiples and Hyper-text' which were related with Simulacre thinking. The main characteristics of expression in Fashion Illustration were 'Virtuality and Multiples'. The image of 'Variableness' was an important factor in digital based fashion, but it was restricted within Fashion Illustration because of the 2-dimensional picture. Therefore, the Lenticular imaging process was proposed as an effective method to expand 2-dimensional limit, giving an effect of 'Variableness' in Fashion Illustration. Based on this study, 5 illustration works were proposed. The Lenticular imaging process was applied in making the images of 'Virtuality, Multiples and Variableness' in 5 works. The result of this study can be a basic material to understand the characteristics of modern Fashion Illustration as a meaningful sub-culture, and diverse expressions corresponding with the phases of the times.

MicroSPECT and MicroPET Imaging of Small Animals for Drug Development

  • Jang, Beom-Su
    • Toxicological Research
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    • v.29 no.1
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    • pp.1-6
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    • 2013
  • The process of drug discovery and development requires substantial resources and time. The drug industry has tried to reduce costs by conducting appropriate animal studies together with molecular biological and genetic analyses. Basic science research has been limited to in vitro studies of cellular processes and ex vivo tissue examination using suitable animal models of disease. However, in the past two decades new technologies have been developed that permit the imaging of live animals using radiotracer emission, X-rays, magnetic resonance signals, fluorescence, and bioluminescence. The main objective of this review is to provide an overview of small animal molecular imaging, with a focus on nuclear imaging (single photon emission computed tomography and positron emission tomography). These technologies permit visualization of toxicodynamics as well as toxicity to specific organs by directly monitoring drug accumulation and assessing physiological and/or molecular alterations. Nuclear imaging technology has great potential for improving the efficiency of the drug development process.

Design and Fabrication of a Multi-modal Confocal Endo-Microscope for Biomedical Imaging

  • Kim, Young-Duk;Ahn, Myoung-Ki;Gweon, Dae-Gab
    • Journal of the Optical Society of Korea
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    • v.15 no.3
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    • pp.300-304
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    • 2011
  • Optical microscopes are widely used for medical imaging these days, but biopsy is a lengthy process that causes many problems during the ex-vivo imaging procedure. The endo-microscope has been studied to increase accessibility to the human body and to get in-vivo images to use for medical diagnosis. This research proposes a multi-modal confocal endo-microscope for bio-medical imaging. We introduce the design process for a small endoscopic probe and a coupling mechanism for the probe to make the multi-modal confocal endo-microscope. The endoscopic probe was designed to decrease chromatic and spherical aberrations, which deteriorate the images obtained with the conventional GRIN lens. Fluorescence and reflectance images of various samples were obtained with the proposed endo-microscope. We evaluated the performance of the proposed endo-microscope by analyzing the acquired images, and demonstrate the possibilities of in-vivo medical imaging for early diagnosis.

Initial Study of a Wire Mesh Tomography Sensor for Liquid/Gas Component Investigation

  • Rahiman, M.H.F.;Siow, L.T.;Rahim, R.A.;Zakaria, Z.;Ang, Vernoon
    • Journal of Electrical Engineering and Technology
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    • v.10 no.5
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    • pp.2205-2210
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    • 2015
  • Experimental studies have been carried out to study the principle operation of the conductive type wire-mesh tomography sensor and analyse the wire-mesh tomography sensor for the liquid/gas two-phase flow interface and void fraction distribution in a process column. The measurement of the two-phase flows in the process column is based on the cross-sectional local instantaneous conductivity. The sensor consists of two planes of parallel electrode wires with 16 electrodes each and was placed orthogonally with each plane. The sensor electrode wires were made of tinned copper wire with an outer diameter of 0.91 mm which stretched over the sensor fixture. Therefore, this result in the mesh grid size with 5.53×5.53mm2. The wire-mesh sensor was tested in a horizontal liquid/gas two-phase flows process column with nominal diameter of 95.6 mm and the sampling frequency of 5882.3529 Hz. The tomogram results show that the wire-mesh tomography provides significant results to represent the void fraction distribution in the process column and estimation error was found in the liquid/gas interface level

Coherent Diffraction Imaging at PAL-XFEL

  • Kim, Sangsoo;Nam, Kihyun;Park, Jaehyun;Kim, Kwangoo;Kim, Bongsoo;Ko, Insoo
    • Proceedings of the Korean Vacuum Society Conference
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    • pp.85.2-85.2
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    • 2016
  • With the advent of ultra-short high-intense XFEL (X-ray Free Electron Laser), time-resolved dynamics has become of great importance in exploring femtosecond real-world phenomena of nanoscience and biology. These include studying the response of materials to femtosecond laser excitation and investigating the interaction of XFEL itself with condensed matter. A variety of dynamic phenomena have been investigated such as radiation damage, ultrafast melting process, non-equilibrium phase transitions caused by orbital-lattice-spin couplings. As far as bulk materials are concerned, the sample size has no effect on the following dynamic process. As a result, imaging information is not required by and large. If the sample size is of tens of nanometers, however, sample starts to experience quantum confinement effect which, in turn, affects the following dynamic process. Therefore, to understand the fundamental dynamic phenomena in nano-science, time-resolved imaging information is essential. In this talk, we will briefly introduce scientific highlights achieved in XFEL-based dynamics. In case of bio-imaging, recent scientific topics will be mentioned as well. Finally, we will aim to present feasible topics in ultrafast time-resolved imaging and to discuss the future plan of CXI beamline at PAL-XFEL.

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