• 대한영상의학회지
• /
• 제83권5호
• /
• pp.1147-1152
• /
• 2022

특발 두개내압상승은 특별한 기질적 원인 없이 두개 내압의 증가가 생기는 증후군으로 이 질환의 약 10%에서 두개내 정맥동의 혈전 형성이 생길 수 있다고 알려져 있다. 체중이 정상 범위이며 응고 장애가 없는 특발 두개내압상승 환자에게서 정맥동의 혈전 형성은 간과될 수 있다. 본 증례 보고에서는 특별한 위험인자가 없던 환자에게서 설하신경관의 신경 원성 종양으로 오인되었던 정맥동 혈전의 케이스를 소개하고, 두개 내압상승의 다양한 영상 소견에 대해 고찰하고자 한다.

• 비만대사연구학술지
• /
• 제3권1호
• /
• pp.43-48
• /
• 2024

Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure without detectable causes. Its main symptoms include headache, vision problems, and pulsatile tinnitus. Obesity is a major risk factor for IIH; therefore, weight reduction is required to ameliorate these symptoms in patients with obesity and IIH. We present four cases of obesity-related IIH whose symptoms improved through weight reduction. In three patients, the dose of IIH medications, such as acetazolamide, decreased. Based on these cases, we report that weight reduction contributes to the improvement of symptoms in patients with IIH as the main part of treatment. Further clinical research is necessary to evaluate the effects of weight reduction on IIH treatment in Korean patients.

• Journal of Yeungnam Medical Science
• /
• 제21권1호
• /
• pp.96-100
• /
• 2004

Behcet's disease is a chronic, relapsing multisystem disorder, that may develop into variable neurological manifestations. They include vascular and parenchymal involvement. Vascular involvement is dominated by cerebral venous sinus thrombosis marked by benign intracranial hypertension. Cerebral venous sinus thrombosis can present with all the classical criteria for idiopathic intracranial hypertension, including normal brain CT findings with normal CSF content. But brain MRI is a useful diagnostic method in this situation to confirm the presence of cerebral venous sinus thrombosis. We experienced a case of raised intracranial pressure in a 21-year-old man, caused by cerebral venous sinus thrombosis. We disclosed his symptoms and signs thus fulfilling the diagnostic criteria for Behcet's disease.

• Korean Journal of Radiology
• /
• 제25권1호
• /
• pp.74-85
• /
• 2024

Objective: Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology associated with venous sinus stenosis. This study aimed to develop a magnetic resonance venography (MRV)-based radiomics model for predicting a high trans-stenotic pressure gradient (TPG) in IIH patients diagnosed with venous sinus stenosis. Materials and Methods: This retrospective study included 105 IIH patients (median age [interquartile range], 35 years [27-42 years]; female:male, 82:23) who underwent MRV and catheter venography complemented by venous manometry. Contrast enhanced-MRV was conducted under 1.5 Tesla system, and the images were reconstructed using a standard algorithm. Shape features were derived from MRV images via the PyRadiomics package and selected by utilizing the least absolute shrinkage and selection operator (LASSO) method. A radiomics score for predicting high TPG (≥ 8 mmHg) in IIH patients was formulated using multivariable logistic regression; its discrimination performance was assessed using the area under the receiver operating characteristic curve (AUROC). A nomogram was constructed by incorporating the radiomics scores and clinical features. Results: Data from 105 patients were randomly divided into two distinct datasets for model training (n = 73; 50 and 23 with and without high TPG, respectively) and testing (n = 32; 22 and 10 with and without high TPG, respectively). Three informative shape features were identified in the training datasets: least axis length, sphericity, and maximum three-dimensional diameter. The radiomics score for predicting high TPG in IIH patients demonstrated an AUROC of 0.906 (95% confidence interval, 0.836-0.976) in the training dataset and 0.877 (95% confidence interval, 0.755-0.999) in the test dataset. The nomogram showed good calibration. Conclusion: Our study presents the feasibility of a novel model for predicting high TPG in IIH patients using radiomics analysis of noninvasive MRV-based shape features. This information may aid clinicians in identifying patients who may benefit from stenting.

• Investigative Magnetic Resonance Imaging
• /
• 제21권3호
• /
• pp.192-194
• /
• 2017

Giant arachnoid granulations have been reported to be associated with headaches, which can be acute or chronic in presentation. In some cases, idiopathic intracranial hypertension, previously called pseudotumor cerebri, may occur. The pathophysiology of these enlarged structures seen as filling defects on imaging is not clearly defined, although they are presumed to cause symptoms such as headache via pressure resulting from secondary venous sinus obstruction. We present a unique presentation of secondary headache in a 39-year-old man with no prior history of headaches found to have giant arachnoid granulations, presenting as migraine with aura.

• 동의생리병리학회지
• /
• 제22권3호
• /
• pp.699-702
• /
• 2008

Oculomotor nerve palsy is a disorder which causes eyeball movement trouble, dipleopia, dizziness and eyelid ptosis. It is caused by aneurysm, mass, truma, intracranial hypertension, diabetes mellitus, infection and so on. But sometimes we can't establish the cause. We report a case of oculomotor nerve palsy associated with spleen energy(脾氣). We treated a patient with herb medicine and acupuncture. This study suggests that oriental medicine theraphy has a good effect on the oculomotor nerve palsy.