• Title/Summary/Keyword: Identify Member

Search Result 319, Processing Time 0.032 seconds

Experimental Study on Stress Evaluation Study on Stress Evaluation of Unbonded Tendon under Ultimate Load (극한하중상태에서 비부착 긴장재의 응력평가에 관한 실험연구)

  • 임재형;문정호;이리형
    • Proceedings of the Korea Concrete Institute Conference
    • /
    • 1998.04b
    • /
    • pp.519-524
    • /
    • 1998
  • The current study is a part of series of research about the evaluation method of the unbonded tendon stress in prestressed concrete member at flexural failure. As the experimental study, a test program with 14 beams and slabs was planed to identify the contribution of each important variable. The variables are (1) the effective prestress, (2) the concrete strength, (3) the amount of tendons (4) the amount of bonded reinforcements, (5) the loading type, (6) the span/depth ratio. It was found that the tendon stress increment decreases as the effective prestress increases. Also, the contributions of concrete strength, amount of tendons, bonded reinforcements, and loading type were observed to affect on tendon stresses. However, the tendon stress increments were minimal at high values of span/depth in contrast with the ACI Code.

  • PDF

High redshift clusters of galaxies

  • Kim, Jae-Woo;Im, Myungshin;Lee, Seong-Kook;Jeon, Yiseul;Hyun, Minhee
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.38 no.2
    • /
    • pp.69.2-69.2
    • /
    • 2013
  • A galaxy cluster is an important laboratory to study the large scale structure in the Universe and the galaxy evolution. In order to identify candidate galaxy clusters at z~1, we have used deep and wide optical-NIR datasets based on IMS, UKIDSS DXS and CFHTLS wide covering ${\sim}20deg^2$ in the SA22 field. We measure the angular two-point correlation function of the candidate clusters and investigate the star formation activity of the member galaxies. Based on bias factor and halo mass function, candidate clusters have the average halo mass of > $10^{14}h^{-1}M_{\odot}$. At z~1, the star formation rate of cluster galaxies is similar to that of field galaxies, which indicates the environmental quenching is not so significant at z~1 as the local Universe.

  • PDF

Cell- and Stage-Specific Expression of the Murine nm23-M5 Gene during Late Spermatogenesis and Spermiogenesis

  • Hwang Gyu-Chan;Ok Do-Won;Lee Mi-Suk;Kim Jin-Hoe
    • Proceedings of the KSAR Conference
    • /
    • 2002.06a
    • /
    • pp.5-5
    • /
    • 2002
  • Nucleoside diphosphate kinases (NDPKs) are conserved through evolution and have been shown to be involved in various biological phenomena. By functional screening in yeast, we identified a new member of the NDPK family, ㎚23-M5, which encodes a 211-amino acid protein with 86% identify to the human homolog, ㎚23-H5. Northern blot analysis reveals that ㎚23-M5 encodes two transcripts of 0.8 and 0.7 kb, which are highly and specifically expressed in adult testis. Reverse transcriptase polymerase chain reaction analysis shows that nm23-M5 first appears in pachytene spermatocytes and increase chain reaction in abundance through subsequent stages. (omitted)

  • PDF

An Examination Performed to Identify the Causative Agent of Crusian Carp (Carassius carassius) Mass Mortality in Jinyangho

  • Shin, Gee-Wook;Lee, Hu-Jang;Jung, Tae-Sung
    • Journal of Environmental Health Sciences
    • /
    • v.29 no.4
    • /
    • pp.1-3
    • /
    • 2003
  • Jinyangho is a natural water supply source of tap water in west Gyeongnam area, but mass mortality of crusian carp occurred during the time of temperature rise in spring. Examinations on diseased fishes were able to isolate four bacteria isolates and then identified the bacteria as a member of Aeromonas sp. Challenge experiment with mirror carp (Gyrinus carpiospecilaris) was proved the virulence, the isolates were in turn believed as the causative agent of mass mortality in Jinyangho.

The regulation of stress induced genes by yeast transcription factor GCN4

  • Seong Kimoon;Lee Jae Yung;Kim Joon
    • Proceedings of the Microbiological Society of Korea Conference
    • /
    • 2002.10a
    • /
    • pp.135-139
    • /
    • 2002
  • Yeast cells respond to condition of amino acid starvation by synthesizing GCN4, a typical eukaryotic transcriptional activator, which regulates the expression of many amino acids biosynthetic genes. By introducing point mutations in the DNA binding domain of GCN4, mutants with normal DNA binding activity but defective in transcriptional activity were isolated to identify unknown proteins that could suppress the mutant phenotype under an amino acid depletion condition. As a result, SSB(Stress-Seventy B) subfamily proteins were identified as suppressors of mutant GCN4. SSB proteins were known as a member of yeast hsp70 family that probably aids passage of nascent chain through ribosomes. Among them, the mechanism of suppression by SSB2 on the defective GCN4 mutant strains is under investigation. Gcn4p directly interacts with Ssb2p through the basic DNA binding domain of GCN4. It suggests the possibility that physical interaction might induce the transcriptional activation of Gcn4p.

  • PDF

A Study on Applying Social Network Centrality Metrics to the Ownership Networks of Large Business Groups (사회네트워크 중심성 지표를 이용한 기업집단 소유네트워크 분석)

  • Park, Chan-Kyoo
    • Korean Management Science Review
    • /
    • v.32 no.2
    • /
    • pp.15-35
    • /
    • 2015
  • Large business groups typically have central firms through which their controlling families establish (or acquire) new firms and maintain control over other member firms. Research on corporate governance has developed metrics to identify those central firms and investigated an impact of the centrality on ownership structure and firm's financial performance. This paper introduces centrality metrics used in social network analysis (SNA) to measure how crucial a role each firm plays in the ownership structure of its business group. Then, the SNA centrality metrics are compared with the metrics developed in corporate governance field. Also, we test the relationship between the SNA centrality metrics and firm's value. Experimental results show that the SNA centrality metrics are closely correlated with the centrality metrics used in corporate governance and are significantly correlated with firm's value.

Fatigue characteristics of the IT girder for railroad (철도교용 IT거더의 피로특성)

  • Choi, Sang-hyun;Lee, Chang-soo
    • Journal of the Society of Disaster Information
    • /
    • v.6 no.2
    • /
    • pp.119-130
    • /
    • 2010
  • In designing a railroad bridge, the fatigue is one of the main factors to be considered for ensuring safe operation. Especially, for a new type of a structural member, which has not been adopted to railroad bridges, the fatigue performance should be checked. In this paper, the fatigue characteristics of an IT girder are examined. The IT girder is a new type of a prestressed concrete girder which has two prestressed H-beams in the top of the girder to give the girder additional sectional capacity. To obtain the fatigue performance, a 10m IT girder specimen is designed, and a repeated load test is performed by applying the load cyclically two million times. The magnitude of the repeated load is determined considering the stress level under the service condition. During the test, static load tests are performed to identify the stiffness degradation. The fatigue performance of the girder is checked according to the Japanese and the CEB-FIB design codes. The fatigue test result shows that the IT girder satisfies both design codes.

Design, Syntheses and Biological Evaluations of Nonpeptidic Caspase 3 Inhibitors

  • Kim, Eun-Sook;Yoo, Sung-Eun;Yi, Kyu-Yang;Lee, Sun-Kyung;Noh, Jae-Sung;Jung, Yong-Sam;Kim, Eun-Hee;Jeong, Nak-Chul
    • Bulletin of the Korean Chemical Society
    • /
    • v.23 no.7
    • /
    • pp.1003-1010
    • /
    • 2002
  • Caspase 3, a member of cysteine protease family, is well known as a major apoptosis effector and is involved in cell death as a result of ischemic diseases such as stroke and myocardial infarction, therefore the inhibition of caspase 3 may protect those apoptotic cell damages. During the high-throughput screening of the compounds from the Korea Chemical Bank, berberine derivatives (A and B), an isoquinoline alkaloid, have been identified as potential inhibitors for caspase 3. Based on this finding we carried out molecular modeling study to identify the pharmacophoric elements of berberine structure which interact with a substrate-recognition binding site of caspase 3 and came up with several novel scaffolds. In this report, we will discuss the molecular modeling, syntheses and the enzyme inhibitory activities of these novel compounds.

A Study on the Relationships between Organizational and Technological Maturity of Korean Enterprise Networks (국내 기업 통신망의 환경 및 기술 성숙도 상관관계 연구)

  • Hong, Ki-Hyang;Juhn, Sung-Hyun;Choi, Heung-Sik
    • Asia pacific journal of information systems
    • /
    • v.10 no.2
    • /
    • pp.97-123
    • /
    • 2000
  • This paper proposes a model for assessing enterprise network maturity. We define maturity in terms of the institutional and member support for the network(organizational maturity) and its technical sophistication(technological maturity), and examine their relationships. We build several hypotheses about the relationships between the maturity types and between the maturity of the network and various organizational factors including industry, size, and performance of the enterprise. We test the hypotheses using data collected from a questionnaire survey with Korean firms. The results show that there is a positive correlation between organizational and technological maturity. It is also found that investment in the network infrastructure has a positive influence on the organizational efficiency. However, it is found that industry type does not affect network utilization, but size does, suggesting that large firms utilize network infrastructure more than small ones do. We also identify various relationships among performance, satisfaction level and the maturity of the enterprise networks. Finally, we provide an overview on the current technological state of the Korean enterprise networks.

  • PDF

A proteomic approach to identify yeast proteins responding to accumulation of misfolded proteins inside the cells

  • Shin, Yong-Seung;Seo, Eun-Joo;Kim, Joon;Yu, Myeong-Hee
    • Proceedings of the Korean Biophysical Society Conference
    • /
    • 2003.06a
    • /
    • pp.57-57
    • /
    • 2003
  • In growing number of diseases it has been shown that aggregation of specific proteins has an important role in pathogenesis of the disorder. This has been demonstrated in structural details with the liver cirrhosis of ${\alpha}$$_1$-antitrypsin deficiency, and it is now believed that similar protein aggregation underlies many neurodegenerative disorders such as autosomal dominant Parkinson disease, prion diseases, Alzheimer disease, and Huntington disease. ${\alpha}$$_1$-Antieypsin, a member of serine pretense inhibitor (serpin) family, functions as an inhibitor of neutrophil elastase.

  • PDF